JP2014510047A5 - - Google Patents
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- Publication number
- JP2014510047A5 JP2014510047A5 JP2013552879A JP2013552879A JP2014510047A5 JP 2014510047 A5 JP2014510047 A5 JP 2014510047A5 JP 2013552879 A JP2013552879 A JP 2013552879A JP 2013552879 A JP2013552879 A JP 2013552879A JP 2014510047 A5 JP2014510047 A5 JP 2014510047A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- antibody
- treatment
- patient
- variant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11001135 | 2011-02-11 | ||
| EP11001135.0 | 2011-02-11 | ||
| PCT/EP2012/000548 WO2012107211A1 (en) | 2011-02-11 | 2012-02-07 | Anti-alpha-v integrin antibody for the treatment of prostate cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016250652A Division JP6488273B2 (ja) | 2011-02-11 | 2016-12-26 | 前立腺癌治療のための抗アルファ−ｖインテグリン抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014510047A JP2014510047A (ja) | 2014-04-24 |
| JP2014510047A5 true JP2014510047A5 (enExample) | 2015-04-02 |
| JP6320042B2 JP6320042B2 (ja) | 2018-05-09 |
Family
ID=45569571
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013552879A Expired - Fee Related JP6320042B2 (ja) | 2011-02-11 | 2012-02-07 | 前立腺癌治療のための抗アルファ−ｖインテグリン抗体 |
| JP2016250652A Expired - Fee Related JP6488273B2 (ja) | 2011-02-11 | 2016-12-26 | 前立腺癌治療のための抗アルファ−ｖインテグリン抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016250652A Expired - Fee Related JP6488273B2 (ja) | 2011-02-11 | 2016-12-26 | 前立腺癌治療のための抗アルファ−ｖインテグリン抗体 |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US9555110B2 (enExample) |
| EP (2) | EP3415162A1 (enExample) |
| JP (2) | JP6320042B2 (enExample) |
| KR (2) | KR102103701B1 (enExample) |
| CN (1) | CN103347540B (enExample) |
| AU (2) | AU2012216145B2 (enExample) |
| CA (1) | CA2827052C (enExample) |
| DK (1) | DK2672994T3 (enExample) |
| EA (1) | EA032117B1 (enExample) |
| ES (1) | ES2683347T3 (enExample) |
| HR (1) | HRP20181212T1 (enExample) |
| HU (1) | HUE037212T2 (enExample) |
| IL (1) | IL227687B (enExample) |
| LT (1) | LT2672994T (enExample) |
| MX (2) | MX385144B (enExample) |
| PL (1) | PL2672994T3 (enExample) |
| PT (1) | PT2672994T (enExample) |
| RS (1) | RS57524B1 (enExample) |
| SG (1) | SG192667A1 (enExample) |
| SI (1) | SI2672994T1 (enExample) |
| TR (1) | TR201810294T4 (enExample) |
| WO (1) | WO2012107211A1 (enExample) |
| ZA (1) | ZA201306807B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2683347T3 (es) | 2011-02-11 | 2018-09-26 | Merck Patent Gmbh | Anticuerpo anti-integrina alfa-v para el tratamiento de cáncer de próstata |
| JP7372025B2 (ja) | 2014-09-17 | 2023-10-31 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 固形がんおよび／またはその転移を処置する方法、そのための薬剤、ならびに固形がんおよび／またはその転移処置の臨床転帰を予測する方法 |
| KR20170055540A (ko) * | 2014-09-17 | 2017-05-19 | 메르크 파텐트 게엠베하 | 뼈 전이 질환 치료 방법, 그에 따른 약제, 및 뼈 전이 질환 치료의 임상 결과 예측 방법 |
| MX2018006269A (es) * | 2015-11-23 | 2018-09-05 | Merck Patent Gmbh | Anticuerpo anti-alfa-v-integrina para el tratamiento de fibrosis y/o trastornos fibroticos. |
| HK1254295A1 (zh) | 2015-11-23 | 2019-07-19 | 默克专利股份有限公司 | 用於治疗纤维化和/或纤维化病症的抗-αＶ整合素抗体 |
| WO2024137442A1 (en) | 2022-12-21 | 2024-06-27 | Gilead Sciences, Inc. | Combination therapy for treating cancer |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU658396B2 (en) | 1991-03-06 | 1995-04-13 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Humanized and chimeric monoclonal antibodies |
| US5753230A (en) | 1994-03-18 | 1998-05-19 | The Scripps Research Institute | Methods and compositions useful for inhibition of angiogenesis |
| ATE244306T1 (de) | 1994-12-20 | 2003-07-15 | Merck Patent Gmbh | Monoklonaler antikörper gegen das alpha-v- integrin |
| DE19534177A1 (de) | 1995-09-15 | 1997-03-20 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
| EP0983303B1 (en) | 1997-05-21 | 2006-03-08 | Biovation Limited | Method for the production of non-immunogenic proteins |
| DE19842415A1 (de) | 1998-09-16 | 2000-03-23 | Merck Patent Gmbh | Pharmazeutische Zubereitung |
| AU776910B2 (en) | 1998-12-08 | 2004-09-23 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Modifying protein immunogenicity |
| US7163681B2 (en) * | 2000-08-07 | 2007-01-16 | Centocor, Inc. | Anti-integrin antibodies, compositions, methods and uses |
| JP4279554B2 (ja) | 2001-02-19 | 2009-06-17 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｔ細胞エピトープの識別方法および低減された免疫原性を有する分子の製造方法 |
| DE10163459A1 (de) | 2001-12-21 | 2003-07-03 | Merck Patent Gmbh | Lyophilisierte Zubereitung enthaltend Antikörper gegen EGF-Rezeptor |
| MXPA05005558A (es) | 2002-11-26 | 2005-07-26 | Protein Design Labs Inc | Anticuerpos quimericos y humanizados para integrina ( 5 ( 1 que modulan la angiogenesis. |
| US8147832B2 (en) | 2003-08-14 | 2012-04-03 | Merck Patent Gmbh | CD20-binding polypeptide compositions and methods |
| EP1713502A1 (de) | 2004-02-12 | 2006-10-25 | MERCK PATENT GmbH | Hochkonzentrierte, flüssige formulierungen von anti-egfr-antikörpern |
| KR20060002667A (ko) | 2004-07-03 | 2006-01-09 | 삼성전자주식회사 | 디스크 댐퍼와 디스크 프로텍터를 구비한 하드 디스크드라이브 |
| US8202465B2 (en) | 2004-11-03 | 2012-06-19 | Honeywell International Inc. | Preferential curing technique in compression molding of fiber reinforced composites |
| US20070025889A1 (en) | 2005-07-28 | 2007-02-01 | Pcbu Business Services, Inc. | Reactors, reactor assemblies and production processes |
| DE102005062440B4 (de) | 2005-12-27 | 2011-02-24 | Lts Lohmann Therapie-Systeme Ag | Proteinbasiertes Trägersystem zur Resistenzüberwindung von Tumorzellen |
| AU2006332155B2 (en) | 2005-12-30 | 2013-01-10 | Cancer Research Technology Limited | Anti-CD19 antibodies with reduced immunogenicity |
| KR20080089489A (ko) | 2006-01-18 | 2008-10-06 | 메르크 파텐트 게엠베하 | 인테그린 리간드를 사용하는 암치료용 특이적 요법 |
| WO2008008435A2 (en) | 2006-07-14 | 2008-01-17 | Rutgers, The State University | Methods, systems, and compositions for extracellular matrix production |
| CN101687039B (zh) | 2007-07-17 | 2014-04-16 | 默克专利有限公司 | 工程化抗αν-整联蛋白杂合抗体 |
| WO2009026328A2 (en) | 2007-08-21 | 2009-02-26 | Immune Disease Institute, Inc. | Methods of delivery of agents to leukocytes and endothelial cells |
| DK2368118T3 (da) | 2008-12-23 | 2013-11-25 | Merck Patent Gmbh | Biomarkører til inhibitorer med anti-angiogen aktivitet |
| BR112012003686B1 (pt) | 2009-08-19 | 2021-09-21 | Merck Patent Gmbh | Anticorpos monoclonais, seu uso para detecção de complexos de integrina em material ffpe, e polinucleotídeo |
| JP2013510804A (ja) | 2009-11-13 | 2013-03-28 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 化学療法剤を装荷したナノ粒子に結合した抗インテグリン抗体 |
| WO2011162933A1 (en) * | 2010-06-04 | 2011-12-29 | Immunogen, Inc. | Anti-integrin immunoconjugate dosing regimens |
| ES2683347T3 (es) | 2011-02-11 | 2018-09-26 | Merck Patent Gmbh | Anticuerpo anti-integrina alfa-v para el tratamiento de cáncer de próstata |
| JP6035716B2 (ja) | 2011-08-26 | 2016-11-30 | ソニー株式会社 | 情報処理システム及び情報処理方法 |
| WO2014143383A1 (en) | 2013-03-13 | 2014-09-18 | Agilent Technologies, Inc. | Transposome tethered to a gene delivery vehicle |
| EP3712166A1 (en) | 2013-09-05 | 2020-09-23 | Amgen Inc. | Fc-containing molecules exhibiting predictable, consistent, and reproducible glycoform profiles |
-
2012
- 2012-02-07 ES ES12702990.8T patent/ES2683347T3/es active Active
- 2012-02-07 KR KR1020197011392A patent/KR102103701B1/ko not_active Expired - Fee Related
- 2012-02-07 MX MX2017014184A patent/MX385144B/es unknown
- 2012-02-07 PL PL12702990T patent/PL2672994T3/pl unknown
- 2012-02-07 CA CA2827052A patent/CA2827052C/en active Active
- 2012-02-07 WO PCT/EP2012/000548 patent/WO2012107211A1/en not_active Ceased
- 2012-02-07 EA EA201391147A patent/EA032117B1/ru not_active IP Right Cessation
- 2012-02-07 SG SG2013060140A patent/SG192667A1/en unknown
- 2012-02-07 EP EP18170936.1A patent/EP3415162A1/en not_active Withdrawn
- 2012-02-07 MX MX2013009062A patent/MX352025B/es active IP Right Grant
- 2012-02-07 AU AU2012216145A patent/AU2012216145B2/en not_active Ceased
- 2012-02-07 HU HUE12702990A patent/HUE037212T2/hu unknown
- 2012-02-07 LT LTEP12702990.8T patent/LT2672994T/lt unknown
- 2012-02-07 DK DK12702990.8T patent/DK2672994T3/en active
- 2012-02-07 KR KR1020137023946A patent/KR101972533B1/ko not_active Expired - Fee Related
- 2012-02-07 CN CN201280008336.1A patent/CN103347540B/zh not_active Expired - Fee Related
- 2012-02-07 HR HRP20181212TT patent/HRP20181212T1/hr unknown
- 2012-02-07 TR TR2018/10294T patent/TR201810294T4/tr unknown
- 2012-02-07 US US13/984,669 patent/US9555110B2/en active Active
- 2012-02-07 PT PT12702990T patent/PT2672994T/pt unknown
- 2012-02-07 SI SI201231356T patent/SI2672994T1/sl unknown
- 2012-02-07 RS RS20180926A patent/RS57524B1/sr unknown
- 2012-02-07 EP EP12702990.8A patent/EP2672994B1/en active Active
- 2012-02-07 JP JP2013552879A patent/JP6320042B2/ja not_active Expired - Fee Related
-
2013
- 2013-07-29 IL IL227687A patent/IL227687B/en active IP Right Grant
- 2013-09-10 ZA ZA2013/06807A patent/ZA201306807B/en unknown
-
2016
- 2016-12-26 JP JP2016250652A patent/JP6488273B2/ja not_active Expired - Fee Related
-
2017
- 2017-01-09 US US15/401,971 patent/US20170218070A1/en not_active Abandoned
- 2017-02-14 AU AU2017200998A patent/AU2017200998B2/en not_active Ceased
-
2019
- 2019-01-25 US US16/258,289 patent/US20190263913A1/en not_active Abandoned
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