|
ES2369542T3
(es)
*
|
2002-07-31 |
2011-12-01 |
Seattle Genetics, Inc. |
Conjugados de auristatina y su uso para tratar cáncer, una enfermedad autoinmune o una enfermedad infecciosa.
|
|
ES2605443T3
(es)
|
2003-11-06 |
2017-03-14 |
Seattle Genetics, Inc. |
Conjugados de auristatina con anticuerpos anti-HER2 o anti-CD22 y su uso en terapia
|
|
ZA200900545B
(en)
*
|
2006-07-18 |
2010-03-31 |
Sanofi Aventis |
Antagonist antibody against EPHA2 for the treatment of cancer
|
|
WO2008151819A2
(en)
|
2007-06-15 |
2008-12-18 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Treatment of tumors using specific anti-l1 antibody
|
|
PE20140625A1
(es)
|
2007-07-16 |
2014-05-29 |
Genentech Inc |
ANTICUERPOS ANTI-CD79b E INMUNOCONJUGADOS HUMANIZADOS
|
|
PT2474557E
(pt)
|
2007-07-16 |
2014-12-03 |
Genentech Inc |
Anticorpos e imunoconjugados anti-cd79b e métodos de utilização
|
|
WO2009028639A1
(ja)
*
|
2007-08-30 |
2009-03-05 |
Daiichi Sankyo Company, Limited |
抗epha2抗体
|
|
WO2009087462A2
(en)
*
|
2007-12-24 |
2009-07-16 |
Oxford Biotherapeutics Ltd. |
Ephrin type-a receptor 10 protein
|
|
DK2657253T3
(en)
|
2008-01-31 |
2017-10-09 |
Genentech Inc |
Anti-CD79b antibodies and immune conjugates and methods of use
|
|
US20100009390A1
(en)
*
|
2008-05-09 |
2010-01-14 |
The Regents Of The University Of California |
Mutant antibodies with high affinity for egfr
|
|
US20100008978A1
(en)
*
|
2008-05-09 |
2010-01-14 |
The Regents Of The University Of California |
Nanoparticles effective for internalization into cells
|
|
UY32914A
(es)
|
2009-10-02 |
2011-04-29 |
Sanofi Aventis |
Anticuerpos que se usan específicamente al receptor epha2
|
|
BR112012019780A2
(pt)
*
|
2010-02-08 |
2020-09-01 |
Agensys, Inc. |
conjugados de fármaco e anticorpo (adc) que ligam a proteínas 161p2f10b
|
|
AU2011223789A1
(en)
|
2010-03-01 |
2012-09-20 |
Caris Life Sciences Switzerland Holdings Gmbh |
Biomarkers for theranostics
|
|
KR20130043104A
(ko)
|
2010-04-06 |
2013-04-29 |
카리스 라이프 사이언스 룩셈부르크 홀딩스 |
질병용 순환 생물학적 지표들
|
|
SG185416A1
(en)
|
2010-05-06 |
2012-12-28 |
Novartis Ag |
Compositions and methods of use for therapeutic low density lipoprotein -related protein 6 (lrp6) antibodies
|
|
NZ603581A
(en)
|
2010-06-19 |
2015-05-29 |
Sloan Kettering Inst Cancer |
Anti-gd2 antibodies
|
|
KR20130048242A
(ko)
|
2010-07-22 |
2013-05-09 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
항-종양 항원 항체 및 이용 방법
|
|
ME02637B
(me)
|
2010-08-20 |
2017-06-20 |
Novartis Ag |
Antitela za receptor 3 faktora rasta epiderma (her3)
|
|
WO2012069466A1
(en)
|
2010-11-24 |
2012-05-31 |
Novartis Ag |
Multispecific molecules
|
|
PT3156420T
(pt)
|
2010-12-06 |
2019-05-27 |
Seattle Genetics Inc |
Anticorpos humanizados a liv-1 e seu uso para tratar o cancro
|
|
PH12013501137A1
(en)
|
2010-12-08 |
2021-06-02 |
Abbvie Stemcentrx Llc |
Novel modulators and methods of use
|
|
SA112330278B1
(ar)
|
2011-02-18 |
2015-10-09 |
ستيم سينتركس، انك. |
مواد ضابطة جديدة وطرق للاستخدام
|
|
SG194567A1
(en)
*
|
2011-04-21 |
2013-12-30 |
Seattle Genetics Inc |
Novel binder-drug conjugates (adcs) and their use
|
|
DK2707031T3
(da)
*
|
2011-05-08 |
2019-10-07 |
Legochem Biosciences Inc |
Protein-active agent conjugates and method for preparing the same
|
|
CN108424456B
(zh)
|
2011-11-23 |
2022-04-26 |
医学免疫有限责任公司 |
特异于her3的结合分子及其用途
|
|
EP2788382A2
(en)
|
2011-12-05 |
2014-10-15 |
Novartis AG |
Antibodies for epidermal growth factor receptor 3 (her3) directed to domain ii of her3
|
|
CN108341873B
(zh)
|
2011-12-05 |
2022-03-25 |
诺华股份有限公司 |
表皮生长因子受体3(her3)的抗体
|
|
SG11201407017WA
(en)
|
2012-06-04 |
2014-12-30 |
Irm Llc |
Site-specific labeling methods and molecules produced thereby
|
|
IN2014DN10889A
(enExample)
*
|
2012-07-13 |
2015-09-11 |
Univ Pennsylvania |
|
|
CN112587671A
(zh)
|
2012-07-18 |
2021-04-02 |
博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
|
DK2839860T3
(da)
|
2012-10-12 |
2019-06-17 |
Medimmune Ltd |
Pyrrolobenzodiazepiner og konjugater deraf
|
|
US9353150B2
(en)
|
2012-12-04 |
2016-05-31 |
Massachusetts Institute Of Technology |
Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment
|
|
WO2014124258A2
(en)
|
2013-02-08 |
2014-08-14 |
Irm Llc |
Specific sites for modifying antibodies to make immunoconjugates
|
|
EA201591465A1
(ru)
|
2013-02-08 |
2015-12-30 |
АйАрЭм ЭлЭлСи |
Специфичные участки для модификации антител для получения иммуноконъюгатов
|
|
US9498532B2
(en)
|
2013-03-13 |
2016-11-22 |
Novartis Ag |
Antibody drug conjugates
|
|
ES2687439T3
(es)
|
2013-03-13 |
2018-10-25 |
Medimmune Limited |
Pirrolobenzodiazepinas y conjugados de las mismas
|
|
WO2014165271A2
(en)
*
|
2013-03-13 |
2014-10-09 |
Neotope Biosciences Limited |
Tau immunotherapy
|
|
WO2014159239A2
(en)
|
2013-03-14 |
2014-10-02 |
Novartis Ag |
Antibodies against notch 3
|
|
AU2014228772B2
(en)
|
2013-03-15 |
2019-02-28 |
Memorial Sloan Kettering Cancer Center |
High affinity anti-GD2 antibodies
|
|
MX366978B
(es)
|
2013-03-15 |
2019-08-01 |
Novartis Ag |
Conjugados de anticuerpo - farmaco.
|
|
US11305012B2
(en)
|
2013-09-24 |
2022-04-19 |
Medimmune, Llc |
Binding molecules specific for HER3 and uses thereof
|
|
RU2016119491A
(ru)
*
|
2013-11-04 |
2017-12-11 |
Пфайзер Инк. |
Конъюгаты антитела к efna4 с лекарственным средством
|
|
EP3092256B1
(en)
|
2014-01-10 |
2022-05-18 |
Birdie Biopharmaceuticals Inc. |
Compounds and compositions for immunotherapy
|
|
BR112016020065A2
(pt)
|
2014-03-12 |
2018-02-20 |
Novartis Ag |
sítios específicos para modificar anticorpos para fazer imunoconjugados
|
|
US10745490B2
(en)
|
2014-04-11 |
2020-08-18 |
Celldex Therapeutics, Inc. |
Anti-ErbB antibodies and methods of use thereof
|
|
SMT202100146T1
(it)
|
2014-04-30 |
2021-05-07 |
Pfizer |
Coniugati di anticorpo anti-ptk7-farmaco
|
|
DK4001311T3
(da)
|
2014-07-09 |
2026-02-02 |
Birdie Biopharmaceuticals Inc |
Anti-pd-l1/pd-1-kombinationer til behandling af tumorer
|
|
AU2015287749B2
(en)
*
|
2014-07-11 |
2021-03-11 |
The Regents Of The University Of California |
Tumor selective macropinocytosis-dependent rapidly internalizing antibodies
|
|
WO2016020791A1
(en)
|
2014-08-05 |
2016-02-11 |
Novartis Ag |
Ckit antibody drug conjugates
|
|
MX2017001946A
(es)
|
2014-08-12 |
2017-06-19 |
Novartis Ag |
Conjugados de farmacos con anticuerpos anti-cdh6.
|
|
CN112546238A
(zh)
*
|
2014-09-01 |
2021-03-26 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-pd-l1结合物
|
|
EP3193940A1
(en)
|
2014-09-10 |
2017-07-26 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
CA2979671C
(en)
|
2014-09-23 |
2020-03-10 |
Genentech, Inc. |
Methods of using anti-cd79b immunoconjugates
|
|
EP3200822B1
(en)
|
2014-09-30 |
2021-04-14 |
Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts |
Binding molecules, especially antibodies, binding to l1cam (cd171)
|
|
EP3549583A1
(en)
*
|
2014-10-10 |
2019-10-09 |
Pfizer Inc |
Synergistic auristatin combinations
|
|
NZ731185A
(en)
|
2014-10-29 |
2024-03-22 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for mt1-mmp
|
|
UY36401A
(es)
|
2014-11-14 |
2016-06-30 |
Novartis Ag |
Conjugados anticuerpos-fármacos
|
|
WO2016081601A1
(en)
*
|
2014-11-19 |
2016-05-26 |
Memorial Sloan-Kettering Cancer Center |
Methods and compositions for cancer treating conditions relating to over expressions of epha2
|
|
US20190194315A1
(en)
|
2015-06-17 |
2019-06-27 |
Novartis Ag |
Antibody drug conjugates
|
|
CN106943596A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技(北京)有限公司 |
用于治疗肿瘤的抗-cd20组合
|
|
CN106943598A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技(北京)有限公司 |
用于治疗肿瘤的抗-her2组合
|
|
CN106943597A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技(北京)有限公司 |
用于治疗肿瘤的抗-egfr组合
|
|
EP3851457A1
(en)
|
2016-01-21 |
2021-07-21 |
Novartis AG |
Multispecific molecules targeting cll-1
|
|
EA201891968A1
(ru)
|
2016-03-15 |
2019-02-28 |
Сиэтл Дженетикс, Инк. |
Комбинированное лечение с использованием liv1-adc и химиотерапевтического средства
|
|
US10918627B2
(en)
|
2016-05-11 |
2021-02-16 |
Massachusetts Institute Of Technology |
Convergent and enantioselective total synthesis of Communesin analogs
|
|
CN109862919A
(zh)
|
2016-10-11 |
2019-06-07 |
免疫医疗有限公司 |
抗体-药物缀合物联合免疫介导的治疗剂
|
|
DK3529269T3
(da)
|
2016-10-19 |
2026-02-23 |
Invenra Inc |
Antistof-konstruktioner
|
|
WO2018115485A1
(en)
|
2016-12-22 |
2018-06-28 |
Pierfrancesco Tassone |
A monoclonal antibody targeting a unique sialoglycosilated cancer-associated epitope of cd43
|
|
JOP20190187A1
(ar)
|
2017-02-03 |
2019-08-01 |
Novartis Ag |
مترافقات عقار جسم مضاد لـ ccr7
|
|
WO2018185618A1
(en)
|
2017-04-03 |
2018-10-11 |
Novartis Ag |
Anti-cdh6 antibody drug conjugates and anti-gitr antibody combinations and methods of treatment
|
|
CN108794467A
(zh)
|
2017-04-27 |
2018-11-13 |
博笛生物科技有限公司 |
2-氨基-喹啉衍生物
|
|
EP3615068A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
US11932650B2
(en)
|
2017-05-11 |
2024-03-19 |
Massachusetts Institute Of Technology |
Potent agelastatin derivatives as modulators for cancer invasion and metastasis
|
|
FI3641771T3
(fi)
|
2017-06-23 |
2026-08-11 |
Birdie Biopharmaceuticals Inc |
Farmaseuttisia koostumuksia
|
|
WO2019002842A1
(en)
|
2017-06-26 |
2019-01-03 |
Bicyclerd Limited |
BICYCLIC PEPTIDE LIGANDS WITH DETECTABLE FRACTIONS AND USES THEREOF
|
|
EP4085919A3
(en)
|
2017-07-21 |
2023-02-08 |
Novartis AG |
Compositions and methods to treat cancer
|
|
JP7670481B2
(ja)
|
2017-08-04 |
2025-04-30 |
バイスクルテクス・リミテッド |
Cd137に対して特異的な二環式ペプチドリガンド
|
|
EP3694545A4
(en)
*
|
2017-10-11 |
2021-12-01 |
Board Of Regents, The University Of Texas System |
HUMAN PD-L1 ANTIBODIES AND METHOD OF USING THEM
|
|
US10640508B2
(en)
|
2017-10-13 |
2020-05-05 |
Massachusetts Institute Of Technology |
Diazene directed modular synthesis of compounds with quaternary carbon centers
|
|
EP3712170A4
(en)
*
|
2017-11-10 |
2022-03-02 |
Jiangsu Hengrui Medicine Co., Ltd. |
CD96 ANTIBODY, ANTIGEN BINDING FRAGMENT AND PHARMACEUTICAL USE THEREOF
|
|
CA3091775A1
(en)
|
2018-02-23 |
2019-08-29 |
Bicycletx Limited |
Multimeric bicyclic peptide ligands
|
|
US11976128B2
(en)
|
2018-03-23 |
2024-05-07 |
Board Of Regents, The University Of Texas System |
Human PD-L2 antibodies and methods of use therefor
|
|
EP3768723A4
(en)
|
2018-03-23 |
2021-12-29 |
Board of Regents, The University of Texas System |
Dual specificity antibodies to human pd-l1 and pd-l2 and methods of use therefor
|
|
EP4501355A3
(en)
|
2018-03-23 |
2025-04-30 |
Board Of Regents, The University Of Texas System |
Dual specificity antibodies to pd-l1 and pd-l2 and methods of use therefor
|
|
CA3098103A1
(en)
|
2018-05-23 |
2019-11-28 |
Adc Therapeutics Sa |
Molecular adjuvant
|
|
CN119405833A
(zh)
|
2018-06-01 |
2025-02-11 |
卫材R&D管理有限公司 |
剪接调节抗体-药物缀合物及其使用方法
|
|
CN113227127A
(zh)
|
2018-06-05 |
2021-08-06 |
伦敦大学国王学院 |
向胃肠系统递送酬载的btnl3/8导引构建体
|
|
JP2021526525A
(ja)
*
|
2018-06-07 |
2021-10-07 |
マジェンタ セラピューティクス インコーポレイテッドMagenta Therapeutics, Inc. |
抗体薬物コンジュゲート(adcs)を用いた治療方法
|
|
US11180531B2
(en)
|
2018-06-22 |
2021-11-23 |
Bicycletx Limited |
Bicyclic peptide ligands specific for Nectin-4
|
|
GB201810316D0
(en)
*
|
2018-06-22 |
2018-08-08 |
Bicyclerd Ltd |
Peptide ligands for binding to EphA2
|
|
EP3863672A4
(en)
|
2018-10-11 |
2022-06-29 |
The Scripps Research Institute |
Antibody compounds with reactive arginine and related antibody drug conjugates
|
|
EP3873532A1
(en)
|
2018-10-31 |
2021-09-08 |
Novartis AG |
Dc-sign antibody drug conjugates
|
|
GB201820325D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for psma
|
|
GB201820295D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for MT1-MMP
|
|
GB201820288D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicycle Tx Ltd |
Bicycle peptide ligaands specific for MT1-MMP
|
|
CN120189526A
(zh)
|
2018-12-13 |
2025-06-24 |
卫材R&D管理有限公司 |
荷伯希二烯抗体-药物缀合物及使用方法
|
|
EP3897849A1
(en)
|
2018-12-21 |
2021-10-27 |
BicycleTx Limited |
Bicyclic peptide ligands specific for pd-l1
|
|
AU2019409132B2
(en)
|
2018-12-21 |
2026-08-06 |
Novartis Ag |
Antibodies to PMEL17 and conjugates thereof
|
|
WO2020128527A1
(en)
|
2018-12-21 |
2020-06-25 |
Bicyclerd Limited |
Bicyclic peptide ligands specific for pd-l1
|
|
GB201900529D0
(en)
|
2019-01-15 |
2019-03-06 |
Bicycletx Ltd |
Bicyclic peptide ligands specific for CD38
|
|
WO2020247054A1
(en)
|
2019-06-05 |
2020-12-10 |
Massachusetts Institute Of Technology |
Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof
|
|
TWI860386B
(zh)
|
2019-07-30 |
2024-11-01 |
英商拜西可泰克斯有限公司 |
異質雙環肽複合物
|
|
CN114846030A
(zh)
|
2019-10-23 |
2022-08-02 |
佛罗里达大学研究基金会公司 |
催化抗体38c2的新型缀合化学
|
|
US20230181756A1
(en)
|
2020-04-30 |
2023-06-15 |
Novartis Ag |
Ccr7 antibody drug conjugates for treating cancer
|
|
CN116348476A
(zh)
|
2020-08-03 |
2023-06-27 |
拜斯科技术开发有限公司 |
基于肽的接头
|
|
EP3970752A1
(en)
|
2020-09-17 |
2022-03-23 |
Merck Patent GmbH |
Molecules with solubility tag and related methods
|
|
US20230372528A1
(en)
|
2020-10-16 |
2023-11-23 |
University Of Georgia Research Foundation, Inc. |
Glycoconjugates
|
|
MX2023006010A
(es)
|
2020-11-24 |
2023-06-08 |
Novartis Ag |
Anticuerpos anti-cd48, conjugados de anticuerpo-farmaco, y usos de los mismos.
|
|
GB202102396D0
(en)
|
2021-02-19 |
2021-04-07 |
Adc Therapeutics Sa |
Molecular adjuvant
|
|
WO2022182415A1
(en)
|
2021-02-24 |
2022-09-01 |
Massachusetts Institute Of Technology |
Himastatin derivatives, and processes of preparation thereof, and uses thereof
|
|
EP4301785A4
(en)
|
2021-03-05 |
2025-04-23 |
Atreca, Inc. |
ANTI-EPHA2 ANTIBODIES
|
|
AU2022258829A1
(en)
|
2021-04-16 |
2023-10-26 |
Novartis Ag |
Antibody drug conjugates and methods for making thereof
|
|
KR102963172B1
(ko)
|
2021-10-22 |
2026-05-18 |
상트네어바이오사이언스 주식회사 |
두개의 Fc 도메인을 포함하는 항원 결합 단백질 및 이의 용도
|
|
CN117980327A
(zh)
|
2021-11-03 |
2024-05-03 |
杭州多禧生物科技有限公司 |
抗体的特异性偶联
|
|
CA3251592A1
(en)
|
2022-02-17 |
2025-07-09 |
Novelty Nobility Inc. |
ANTIBODY-DRUG CONJUGATE
|
|
WO2023192976A1
(en)
|
2022-04-01 |
2023-10-05 |
Board Of Regents, The University Of Texas System |
Dual specificity antibodies to human pd-l1 and pd-l2 and methods of use therefor
|
|
EP4525925A1
(en)
|
2022-05-20 |
2025-03-26 |
Novartis AG |
Epha2 bcl-xl inhibitor antibody-drug conjugates and methods of use thereof
|
|
IL317101A
(en)
|
2022-05-20 |
2025-01-01 |
Novartis Ag |
Antibody-drug conjugates of anticancer compounds and methods of using them
|
|
EP4676540A1
(en)
|
2023-03-10 |
2026-01-14 |
Novartis AG |
Panras inhibitor antibody-drug conjugates and methods of use thereof
|
|
TW202504932A
(zh)
|
2023-04-21 |
2025-02-01 |
南韓商百歲生命科學股份有限公司 |
包含兩個fc區域之抗原結合蛋白及其用途
|
|
AU2024400671A1
(en)
|
2023-12-15 |
2026-07-16 |
Kyowa Kirin Co., Ltd. |
Divalent bet decomposition agent and targeting molecule-drug complex
|
|
WO2026069006A1
(en)
|
2024-09-30 |
2026-04-02 |
Sunrise Oncology (Hong Kong) Limited |
Ras inhibitor antibody-drug conjugates and methods of use thereof
|