JP2007504284A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2007504284A5 JP2007504284A5 JP2006533807A JP2006533807A JP2007504284A5 JP 2007504284 A5 JP2007504284 A5 JP 2007504284A5 JP 2006533807 A JP2006533807 A JP 2006533807A JP 2006533807 A JP2006533807 A JP 2006533807A JP 2007504284 A5 JP2007504284 A5 JP 2007504284A5
- Authority
- JP
- Japan
- Prior art keywords
- halo
- compound according
- compound
- alkyl
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47774403P | 2003-06-12 | 2003-06-12 | |
| US60/477,744 | 2003-06-12 | ||
| PCT/US2004/019189 WO2005004866A1 (en) | 2003-06-12 | 2004-06-14 | Therapeutic agents useful for treating pain |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011159464A Division JP2012021000A (ja) | 2003-06-12 | 2011-07-21 | 疼痛を治療するのに有用な治療薬 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007504284A JP2007504284A (ja) | 2007-03-01 |
| JP2007504284A5 true JP2007504284A5 (enExample) | 2011-09-08 |
| JP5269315B2 JP5269315B2 (ja) | 2013-08-21 |
Family
ID=34061917
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006533807A Expired - Fee Related JP5269315B2 (ja) | 2003-06-12 | 2004-06-14 | 疼痛を治療するのに有用な治療薬 |
| JP2011159464A Withdrawn JP2012021000A (ja) | 2003-06-12 | 2011-07-21 | 疼痛を治療するのに有用な治療薬 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011159464A Withdrawn JP2012021000A (ja) | 2003-06-12 | 2011-07-21 | 疼痛を治療するのに有用な治療薬 |
Country Status (28)
| Country | Link |
|---|---|
| US (3) | US7683063B2 (enExample) |
| EP (3) | EP1862458B1 (enExample) |
| JP (2) | JP5269315B2 (enExample) |
| KR (2) | KR20090008439A (enExample) |
| CN (2) | CN101863877A (enExample) |
| AR (1) | AR044688A1 (enExample) |
| AT (2) | ATE369133T1 (enExample) |
| AU (1) | AU2004255169B2 (enExample) |
| BR (1) | BRPI0411241A (enExample) |
| CA (1) | CA2528920C (enExample) |
| CY (1) | CY1108738T1 (enExample) |
| DE (2) | DE602004008069D1 (enExample) |
| DK (1) | DK1862458T3 (enExample) |
| EA (1) | EA009593B1 (enExample) |
| ES (1) | ES2317623T3 (enExample) |
| GE (1) | GEP20084488B (enExample) |
| IL (1) | IL172418A (enExample) |
| IS (1) | IS8142A (enExample) |
| MA (1) | MA27908A1 (enExample) |
| MX (1) | MXPA05013587A (enExample) |
| MY (1) | MY142655A (enExample) |
| NO (1) | NO20060192L (enExample) |
| PL (1) | PL1862458T3 (enExample) |
| PT (1) | PT1862458E (enExample) |
| SI (1) | SI1862458T1 (enExample) |
| TW (1) | TWI287010B (enExample) |
| WO (1) | WO2005004866A1 (enExample) |
| ZA (1) | ZA200508744B (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002060446A1 (fr) | 2001-01-29 | 2002-08-08 | Shionogi & Co., Ltd. | Preparation medicamenteuse contenant du 5-methyle-1-phenyle-2-(1h)-pyridone en tant que principe actif |
| EP1627869B1 (en) | 2003-05-20 | 2012-05-02 | Ajinomoto Co., Inc. | Vanilloid receptor modulators |
| TWI287010B (en) * | 2003-06-12 | 2007-09-21 | Euro Celtique Sa | Therapeutic agents useful for treating pain |
| US20050009841A1 (en) * | 2003-07-11 | 2005-01-13 | Zheng Guo Zhu | Novel amides useful for treating pain |
| GEP20094676B (en) * | 2003-07-24 | 2009-05-10 | Euro Celtique Sa | Piperidine compounds and pharmaceutical compositions containing them |
| DE602004017316D1 (de) | 2003-07-24 | 2008-12-04 | Euro Celtique Sa | Heteroaryl-tetrahydropyridylverbindungen, die sich für die behandlung bzw. die prävention von schmerzen eignen |
| TW200738232A (en) * | 2006-01-31 | 2007-10-16 | Alcon Mfg Ltd | Use of vanilloid receptor-1 antagonists for the prevention and treatment of glaucoma |
| US20080051380A1 (en) | 2006-08-25 | 2008-02-28 | Auerbach Alan H | Methods and compositions for treating cancer |
| KR100801278B1 (ko) * | 2006-08-29 | 2008-02-04 | 삼성전기주식회사 | 하이브리드형 광도파로 센서 |
| US7645767B2 (en) * | 2006-08-31 | 2010-01-12 | Trinity Laboratories, Inc. | Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy |
| US20080153845A1 (en) * | 2006-10-27 | 2008-06-26 | Redpoint Bio Corporation | Trpv1 antagonists and uses thereof |
| MX2009011601A (es) * | 2007-04-27 | 2009-11-10 | Purdue Pharma Lp | Agentes terapeuticos utiles para tratar el dolor. |
| CA2685266C (en) | 2007-04-27 | 2014-01-28 | Purdue Pharma L.P. | Trpv1 antagonists and uses thereof for the treatment of prevention of pain, ui and ulcer, ibd, or ibs in an animal |
| CA2684105C (en) | 2007-05-03 | 2011-09-06 | Pfizer Limited | Pyridine derivatives |
| EP2185538A2 (en) | 2007-08-09 | 2010-05-19 | Abbott Laboratories | Tetrahydropyridine carboxamide derivatives as trpvl antagonists |
| US8084616B2 (en) | 2007-10-24 | 2011-12-27 | Abbott Laboratories | TRPV1 antagonists |
| MX2010014222A (es) * | 2008-06-30 | 2011-03-29 | Novartis Ag Star | Combinaciones que comprenden moduladores de mglur para el tratamiento de enfermedad de parkinson. |
| US8921373B2 (en) | 2010-06-22 | 2014-12-30 | Shionogi & Co., Ltd. | Compounds having TRPV1 antagonistic activity and uses thereof |
| JP6130827B2 (ja) | 2011-05-17 | 2017-05-17 | 塩野義製薬株式会社 | ヘテロ環化合物 |
| PE20141531A1 (es) | 2011-06-22 | 2014-10-23 | Purdue Pharma Lp | Antagonistas de trpv1 que incluyen sustituyentes dihidroxi y sus usos |
| EP2773779B1 (en) * | 2011-11-04 | 2020-10-14 | Population Bio, Inc. | Methods and compositions for diagnosing, prognosing, and treating neurological conditions |
| WO2013146970A1 (ja) * | 2012-03-29 | 2013-10-03 | 第一三共株式会社 | 新規キノリン誘導体 |
| TW201730188A (zh) * | 2015-11-30 | 2017-09-01 | 阿斯特捷利康公司 | 1,3,4-噻二唑化合物及其在治療癌症中之用途 |
| CA2937365C (en) | 2016-03-29 | 2018-09-18 | F. Hoffmann-La Roche Ag | Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| SG11201811023UA (en) | 2016-06-23 | 2019-01-30 | St Jude Childrens Res Hospital | Small molecule modulators of pantothenate kinases |
| UA124972C2 (uk) | 2016-07-29 | 2021-12-22 | Янссен Фармацевтика Нв | Способи лікування раку передміхурової залози |
| GB201709459D0 (en) * | 2017-06-14 | 2017-07-26 | Intrabio Ltd | Treatment for migraine |
| JP6964506B2 (ja) * | 2017-12-19 | 2021-11-10 | ライオン株式会社 | 錠剤及び錠剤の製造方法 |
| WO2019133635A1 (en) | 2017-12-27 | 2019-07-04 | St. Jude Children's Research Hospital | Small molecule modulators of pantothenate kinases |
| JP7527967B2 (ja) | 2017-12-27 | 2024-08-05 | セント ジュード チルドレンズ リサーチ ホスピタル，インコーポレイティド | Ｃａｓｔｏｒに関連する障害を治療する方法 |
| US12460178B2 (en) | 2018-04-12 | 2025-11-04 | Cellresearch Corporation Pte. Ltd. | Method of inducing or improving wound healing properties of mesenchymal stem cells |
| TWI882956B (zh) * | 2018-04-12 | 2025-05-11 | 新加坡商細胞研究私人有限公司 | 一種誘導或改善間質幹細胞傷口癒合特性的方法 |
| WO2020198526A2 (en) | 2019-03-27 | 2020-10-01 | St. Jude Children's Research Hospital | Small molecule modulators of pank |
| RU2744162C1 (ru) * | 2020-03-18 | 2021-03-03 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Пермская государственная фармацевтическая академия" Министерства здравоохранения Российской Федерации (ФГБОУ ВО ПГФА Минздрава России) | Анальгетическое средство на основе 5-(2-аминопропил)-6-оксо-3,4-дифенилпирроло[3,4-c]пиразола |
| KR102885259B1 (ko) | 2020-07-31 | 2025-11-14 | 삼성전자주식회사 | 차폐 및 방열 구조를 포함하는 전자 장치 |
| CN115536648B (zh) * | 2021-06-29 | 2024-09-17 | 深圳开悦生命科技有限公司 | 一类抑制rna解旋酶dhx33的多环化合物及其应用 |
| CN113061593B (zh) * | 2021-04-02 | 2023-11-10 | 洛阳华荣生物技术有限公司 | 一种l-苹果酸脱氢酶突变体及其应用 |
| DE102022104759A1 (de) | 2022-02-28 | 2023-08-31 | SCi Kontor GmbH | Co-Kristall-Screening Verfahren, insbesondere zur Herstellung von Co-Kristallen |
| CN114957214A (zh) * | 2022-06-22 | 2022-08-30 | 九江善水科技股份有限公司 | 一种氯虫苯甲酰胺中间体的制备方法 |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| GB1363215A (en) * | 1973-01-04 | 1974-08-14 | Mullard Ltd | Mechanical-electrical transducer |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| US5053595A (en) * | 1982-12-01 | 1991-10-01 | Metcal, Inc. | Heat shrink sleeve with high mu material |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| JPH0680054B2 (ja) | 1985-06-19 | 1994-10-12 | 吉富製薬株式会社 | ピペリジン誘導体 |
| US5316759A (en) | 1986-03-17 | 1994-05-31 | Robert J. Schaap | Agonist-antagonist combination to reduce the use of nicotine and other drugs |
| US5198459A (en) | 1987-07-11 | 1993-03-30 | Sandoz Ltd. | Use of 5HT-3 antagonists in preventing or reducing dependency on dependency-inducing agents |
| DE3822792C2 (de) | 1987-07-11 | 1997-11-27 | Sandoz Ag | Neue Verwendung von 5HT¶3¶-Antagonisten |
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5075341A (en) | 1989-12-01 | 1991-12-24 | The Mclean Hospital Corporation | Treatment for cocaine abuse |
| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| PT97888B (pt) * | 1990-06-07 | 1998-12-31 | Zeneca Ltd | Processo para a preparacao de compostos heterociclicos derivados de indol e de composicoes farmaceuticas que os contem |
| FR2676734B1 (fr) | 1991-05-23 | 1995-05-19 | Roussel Uclaf | Nouveaux derives de la pyrimidine, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant. |
| US5698155A (en) | 1991-05-31 | 1997-12-16 | Gs Technologies, Inc. | Method for the manufacture of pharmaceutical cellulose capsules |
| US6204284B1 (en) | 1991-12-20 | 2001-03-20 | American Cyanamid Company | Use of 1-(substitutedphenyl)-3-azabicyclo[3.1.0]hexanes for the treatment of chemical dependencies |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| US5232934A (en) | 1992-07-17 | 1993-08-03 | Warner-Lambert Co. | Method for the treatment of psychomotor stimulant addiction |
| DE4234295A1 (de) | 1992-10-12 | 1994-04-14 | Thomae Gmbh Dr K | Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| US5321012A (en) | 1993-01-28 | 1994-06-14 | Virginia Commonwealth University Medical College | Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| US5556837A (en) | 1994-08-01 | 1996-09-17 | Regeneron Pharmaceuticals Inc. | Methods for treating addictive disorders |
| US5762925A (en) | 1994-11-03 | 1998-06-09 | Sagen; Jacqueline | Preventing opiate tolerance by cellular implantation |
| ES2247604T3 (es) | 1995-06-12 | 2006-03-01 | G.D. SEARLE & CO. | Composiciones que comprenden un inhibidor de ciclooxigenasa-2 y un inhibidor de 5-lipoxigenasa. |
| US6063930A (en) | 1996-04-03 | 2000-05-16 | Merck & Co., Inc. | Substituted imidazole compounds useful as farnesyl-protein transferase inhibitors |
| CA2274593A1 (en) | 1996-12-13 | 1998-06-18 | Banyu Pharmaceutical Co., Ltd. | Novel aminopyrazole derivatives |
| US6703362B1 (en) | 1997-05-15 | 2004-03-09 | Cytogen Corporation | Random peptides that bind to gastro-intestinal tract (GIT) transport receptors and related methods |
| WO1999009140A1 (en) | 1997-08-20 | 1999-02-25 | The Regents Of The University Of California | Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof |
| EP0943683A1 (en) | 1998-03-10 | 1999-09-22 | Smithkline Beecham Plc | Human vanilloid receptor homologue Vanilrep1 |
| US6098369A (en) * | 1998-07-17 | 2000-08-08 | Bodolay; William A. | Apparatus for attaching a reclosable fastener to a flexible material |
| AU2055500A (en) | 1998-12-23 | 2000-07-31 | Eli Lilly And Company | Aromatic amides |
| CA2358095A1 (en) * | 1998-12-23 | 2000-07-06 | Eli Lilly And Company | Heteroroaromatic amides as inhibitor of factor xa |
| US6689780B1 (en) | 1998-12-23 | 2004-02-10 | Eli Lilly And Company | Heteroroaromatic amides as inhibitor of factor Xa |
| GB9907097D0 (en) | 1999-03-26 | 1999-05-19 | Novartis Ag | Organic compounds |
| US6632815B2 (en) | 1999-09-17 | 2003-10-14 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
| ATE402704T1 (de) | 2000-03-27 | 2008-08-15 | Abbott Gmbh & Co Kg | Dopamin-d3-rezeptor-liganden zur behandlung von sucht |
| EP1285651B1 (en) | 2000-04-28 | 2010-09-01 | Takeda Pharmaceutical Company Limited | Melanin concentrating hormone antagonists |
| AR028782A1 (es) * | 2000-07-05 | 2003-05-21 | Taisho Pharmaceutical Co Ltd | Derivados heterociclicos tetrahidropiridino o piperidino |
| JP2003142681A (ja) | 2001-10-31 | 2003-05-16 | Sony Corp | 絶縁ゲート型電界効果トランジスタを有する半導体装置 |
| JP2003192673A (ja) | 2001-12-27 | 2003-07-09 | Bayer Ag | ピペラジンカルボキシアミド誘導体 |
| US7071335B2 (en) | 2002-02-01 | 2006-07-04 | Euro-Celtique S.A. | 2-pyridinyl-1-piperazine therapeutic agents useful for treating pain |
| AU2003245773A1 (en) | 2002-02-15 | 2003-09-04 | Glaxo Group Limited | Vanilloid receptor modulators |
| PL377215A1 (pl) | 2002-10-17 | 2006-01-23 | Amgen Inc. | Pochodne benzimidazolu oraz ich zastosowanie w charakterze ligandów receptora waniloidowego |
| US7067509B2 (en) | 2003-03-07 | 2006-06-27 | Neurocrine Biosciences, Inc. | Melanin-concentrating hormone receptor antagonists and compositions and methods related thereto |
| US20050014753A1 (en) | 2003-04-04 | 2005-01-20 | Irm Llc | Novel compounds and compositions as protein kinase inhibitors |
| EP1627869B1 (en) * | 2003-05-20 | 2012-05-02 | Ajinomoto Co., Inc. | Vanilloid receptor modulators |
| TWI287010B (en) | 2003-06-12 | 2007-09-21 | Euro Celtique Sa | Therapeutic agents useful for treating pain |
| US20050009841A1 (en) * | 2003-07-11 | 2005-01-13 | Zheng Guo Zhu | Novel amides useful for treating pain |
| US7129235B2 (en) | 2003-07-11 | 2006-10-31 | Abbott Laboratories | Amides useful for treating pain |
| DE602004017316D1 (de) * | 2003-07-24 | 2008-12-04 | Euro Celtique Sa | Heteroaryl-tetrahydropyridylverbindungen, die sich für die behandlung bzw. die prävention von schmerzen eignen |
| GEP20094676B (en) * | 2003-07-24 | 2009-05-10 | Euro Celtique Sa | Piperidine compounds and pharmaceutical compositions containing them |
| MX2009011601A (es) * | 2007-04-27 | 2009-11-10 | Purdue Pharma Lp | Agentes terapeuticos utiles para tratar el dolor. |
-
2004
- 2004-06-11 TW TW093116961A patent/TWI287010B/zh not_active IP Right Cessation
- 2004-06-11 AR ARP040102043A patent/AR044688A1/es unknown
- 2004-06-11 MY MYPI20042274A patent/MY142655A/en unknown
- 2004-06-14 CA CA2528920A patent/CA2528920C/en not_active Expired - Fee Related
- 2004-06-14 EP EP07113391A patent/EP1862458B1/en not_active Expired - Lifetime
- 2004-06-14 AT AT04776652T patent/ATE369133T1/de active
- 2004-06-14 BR BRPI0411241-5A patent/BRPI0411241A/pt not_active IP Right Cessation
- 2004-06-14 GE GEAP20049166A patent/GEP20084488B/en unknown
- 2004-06-14 DK DK07113391T patent/DK1862458T3/da active
- 2004-06-14 EP EP04776652A patent/EP1631285B1/en not_active Expired - Lifetime
- 2004-06-14 AT AT07113391T patent/ATE413385T1/de active
- 2004-06-14 PL PL07113391T patent/PL1862458T3/pl unknown
- 2004-06-14 AU AU2004255169A patent/AU2004255169B2/en not_active Ceased
- 2004-06-14 WO PCT/US2004/019189 patent/WO2005004866A1/en not_active Ceased
- 2004-06-14 DE DE602004008069T patent/DE602004008069D1/de not_active Expired - Lifetime
- 2004-06-14 JP JP2006533807A patent/JP5269315B2/ja not_active Expired - Fee Related
- 2004-06-14 PT PT07113391T patent/PT1862458E/pt unknown
- 2004-06-14 ES ES07113391T patent/ES2317623T3/es not_active Expired - Lifetime
- 2004-06-14 US US10/867,546 patent/US7683063B2/en not_active Expired - Lifetime
- 2004-06-14 DE DE602004017658T patent/DE602004017658D1/de not_active Expired - Lifetime
- 2004-06-14 MX MXPA05013587A patent/MXPA05013587A/es active IP Right Grant
- 2004-06-14 SI SI200431012T patent/SI1862458T1/sl unknown
- 2004-06-14 EP EP08168291A patent/EP2060260A1/en not_active Withdrawn
- 2004-06-14 KR KR1020087029450A patent/KR20090008439A/ko not_active Withdrawn
- 2004-06-14 CN CN201010168011A patent/CN101863877A/zh active Pending
- 2004-06-14 CN CN200480023060XA patent/CN1835751B/zh not_active Expired - Fee Related
- 2004-06-14 EA EA200501820A patent/EA009593B1/ru not_active IP Right Cessation
- 2004-06-14 KR KR1020057023740A patent/KR100896497B1/ko not_active Expired - Fee Related
-
2005
- 2005-10-28 ZA ZA200508744A patent/ZA200508744B/xx unknown
- 2005-11-23 IS IS8142A patent/IS8142A/is unknown
- 2005-12-06 IL IL172418A patent/IL172418A/en not_active IP Right Cessation
-
2006
- 2006-01-09 MA MA28715A patent/MA27908A1/fr unknown
- 2006-01-12 NO NO20060192A patent/NO20060192L/no not_active Application Discontinuation
-
2009
- 2009-01-30 CY CY20091100110T patent/CY1108738T1/el unknown
-
2010
- 2010-02-16 US US12/706,571 patent/US8227467B2/en not_active Expired - Lifetime
-
2011
- 2011-07-21 JP JP2011159464A patent/JP2012021000A/ja not_active Withdrawn
-
2012
- 2012-06-18 US US13/525,950 patent/US8680118B2/en not_active Expired - Fee Related