JP2007504284A5 - - Google Patents

Download PDF

Info

Publication number
JP2007504284A5
JP2007504284A5 JP2006533807A JP2006533807A JP2007504284A5 JP 2007504284 A5 JP2007504284 A5 JP 2007504284A5 JP 2006533807 A JP2006533807 A JP 2006533807A JP 2006533807 A JP2006533807 A JP 2006533807A JP 2007504284 A5 JP2007504284 A5 JP 2007504284A5
Authority
JP
Japan
Prior art keywords
halo
compound according
compound
alkyl
alkenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006533807A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007504284A (ja
JP5269315B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/019189 external-priority patent/WO2005004866A1/en
Publication of JP2007504284A publication Critical patent/JP2007504284A/ja
Publication of JP2007504284A5 publication Critical patent/JP2007504284A5/ja
Application granted granted Critical
Publication of JP5269315B2 publication Critical patent/JP5269315B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2006533807A 2003-06-12 2004-06-14 疼痛を治療するのに有用な治療薬 Expired - Fee Related JP5269315B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47774403P 2003-06-12 2003-06-12
US60/477,744 2003-06-12
PCT/US2004/019189 WO2005004866A1 (en) 2003-06-12 2004-06-14 Therapeutic agents useful for treating pain

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011159464A Division JP2012021000A (ja) 2003-06-12 2011-07-21 疼痛を治療するのに有用な治療薬

Publications (3)

Publication Number Publication Date
JP2007504284A JP2007504284A (ja) 2007-03-01
JP2007504284A5 true JP2007504284A5 (enExample) 2011-09-08
JP5269315B2 JP5269315B2 (ja) 2013-08-21

Family

ID=34061917

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2006533807A Expired - Fee Related JP5269315B2 (ja) 2003-06-12 2004-06-14 疼痛を治療するのに有用な治療薬
JP2011159464A Withdrawn JP2012021000A (ja) 2003-06-12 2011-07-21 疼痛を治療するのに有用な治療薬

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011159464A Withdrawn JP2012021000A (ja) 2003-06-12 2011-07-21 疼痛を治療するのに有用な治療薬

Country Status (28)

Country Link
US (3) US7683063B2 (enExample)
EP (3) EP2060260A1 (enExample)
JP (2) JP5269315B2 (enExample)
KR (2) KR20090008439A (enExample)
CN (2) CN1835751B (enExample)
AR (1) AR044688A1 (enExample)
AT (2) ATE369133T1 (enExample)
AU (1) AU2004255169B2 (enExample)
BR (1) BRPI0411241A (enExample)
CA (1) CA2528920C (enExample)
CY (1) CY1108738T1 (enExample)
DE (2) DE602004008069D1 (enExample)
DK (1) DK1862458T3 (enExample)
EA (1) EA009593B1 (enExample)
ES (1) ES2317623T3 (enExample)
GE (1) GEP20084488B (enExample)
IL (1) IL172418A (enExample)
IS (1) IS8142A (enExample)
MA (1) MA27908A1 (enExample)
MX (1) MXPA05013587A (enExample)
MY (1) MY142655A (enExample)
NO (1) NO20060192L (enExample)
PL (1) PL1862458T3 (enExample)
PT (1) PT1862458E (enExample)
SI (1) SI1862458T1 (enExample)
TW (1) TWI287010B (enExample)
WO (1) WO2005004866A1 (enExample)
ZA (1) ZA200508744B (enExample)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60234812D1 (de) 2001-01-29 2010-02-04 Shionogi & Co Arzneipräparat, das als wirkstoff 5-methyl-1-phenyl-2-(1h)-pyridon enthält
ATE556067T1 (de) 2003-05-20 2012-05-15 Ajinomoto Kk Modulatoren des vanilloid rezeptors
AR044688A1 (es) 2003-06-12 2005-09-21 Euro Celtique Sa Agentes terapeuticos utiles para el tratamiento del dolor
US20050009841A1 (en) * 2003-07-11 2005-01-13 Zheng Guo Zhu Novel amides useful for treating pain
ES2327684T3 (es) 2003-07-24 2009-11-02 Euro-Celtique S.A. Compuestos heteroaril-tetrahidropiridilo utiles para el tratamiento o la prevencion del dolor.
EP1648878B9 (en) * 2003-07-24 2011-03-16 Euro-Celtique S.A. Piperidine compounds and pharmaceutical compositions containing them
TW200738232A (en) * 2006-01-31 2007-10-16 Alcon Mfg Ltd Use of vanilloid receptor-1 antagonists for the prevention and treatment of glaucoma
US20080051380A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
KR100801278B1 (ko) * 2006-08-29 2008-02-04 삼성전기주식회사 하이브리드형 광도파로 센서
US7645767B2 (en) * 2006-08-31 2010-01-12 Trinity Laboratories, Inc. Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
WO2008057300A2 (en) * 2006-10-27 2008-05-15 Redpoint Bio Corporation Trpvi antagonists and uses thereof
EP2142529B1 (en) 2007-04-27 2013-12-25 Purdue Pharma LP Trpv1 antagonists and uses thereof
CA2685121A1 (en) * 2007-04-27 2008-11-06 Purdue Pharma L.P. Therapeutic agents useful for treating pain
EA015952B1 (ru) 2007-05-03 2011-12-30 Пфайзер Лимитед 2-пиридинкарбоксамидные производные в качестве модуляторов натриевых каналов
MX2010001486A (es) * 2007-08-09 2010-03-01 Abbott Lab Derivados de tetrahidropiridin carboxamida como antagonistas de trpvl.
US8084616B2 (en) 2007-10-24 2011-12-27 Abbott Laboratories TRPV1 antagonists
WO2010000763A2 (en) * 2008-06-30 2010-01-07 Novartis Ag Combination products
US8921373B2 (en) 2010-06-22 2014-12-30 Shionogi & Co., Ltd. Compounds having TRPV1 antagonistic activity and uses thereof
JP6130827B2 (ja) 2011-05-17 2017-05-17 塩野義製薬株式会社 ヘテロ環化合物
RS55701B1 (sr) 2011-06-22 2017-07-31 Purdue Pharma Lp Trpv1 antagonisti koji uključuju dihidroksi supstituent i njihove upotrebe
EP2773779B1 (en) * 2011-11-04 2020-10-14 Population Bio, Inc. Methods and compositions for diagnosing, prognosing, and treating neurological conditions
WO2013146970A1 (ja) * 2012-03-29 2013-10-03 第一三共株式会社 新規キノリン誘導体
US9938265B2 (en) * 2015-11-30 2018-04-10 Astrazeneca Ab 1,3,4-thiadiazole compounds and their use in treating cancer
CA2937365C (en) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Hdac抑制劑與pd-l1抑制劑之組合治療
MX383697B (es) 2016-06-23 2025-03-14 St Jude Childrens Res Hospital Inc Moduladores de moleculas peque?as de pantotenato cinasas
WO2018023017A1 (en) 2016-07-29 2018-02-01 Janssen Pharmaceutica Nv Methods of treating prostate cancer
GB201709459D0 (en) * 2017-06-14 2017-07-26 Intrabio Ltd Treatment for migraine
JP6964506B2 (ja) * 2017-12-19 2021-11-10 ライオン株式会社 錠剤及び錠剤の製造方法
MX2020006754A (es) 2017-12-27 2021-01-29 St Jude Childrens Res Hospital Inc Moduladores de molécula pequeña de pantotenato-cinasas.
WO2019133632A1 (en) 2017-12-27 2019-07-04 St. Jude Children's Research Hospital Methods of treating disorders associated with castor
US12460178B2 (en) 2018-04-12 2025-11-04 Cellresearch Corporation Pte. Ltd. Method of inducing or improving wound healing properties of mesenchymal stem cells
TWI882956B (zh) * 2018-04-12 2025-05-11 新加坡商細胞研究私人有限公司 一種誘導或改善間質幹細胞傷口癒合特性的方法
US12534451B2 (en) 2019-03-27 2026-01-27 St. Jude Children's Research Hospital, Inc. Small molecule modulators of PanK
MD3989962T2 (ro) 2019-06-28 2025-12-31 Intrabio Ltd Gb Terapie combinată cu acetil-leucină și miglustat pentru tratamentul unei boli de depozitare lizozomală
WO2021144720A1 (en) 2020-01-13 2021-07-22 Intrabio Ltd Treatment of late-onset neurodegenerative diseases in heterozygous npc1 gene mutation carriers
RU2744162C1 (ru) * 2020-03-18 2021-03-03 Федеральное государственное бюджетное образовательное учреждение высшего образования "Пермская государственная фармацевтическая академия" Министерства здравоохранения Российской Федерации (ФГБОУ ВО ПГФА Минздрава России) Анальгетическое средство на основе 5-(2-аминопропил)-6-оксо-3,4-дифенилпирроло[3,4-c]пиразола
KR102885259B1 (ko) 2020-07-31 2025-11-14 삼성전자주식회사 차폐 및 방열 구조를 포함하는 전자 장치
CN115536648B (zh) * 2021-06-29 2024-09-17 深圳开悦生命科技有限公司 一类抑制rna解旋酶dhx33的多环化合物及其应用
CN113061593B (zh) * 2021-04-02 2023-11-10 洛阳华荣生物技术有限公司 一种l-苹果酸脱氢酶突变体及其应用
DE102022104759A1 (de) 2022-02-28 2023-08-31 SCi Kontor GmbH Co-Kristall-Screening Verfahren, insbesondere zur Herstellung von Co-Kristallen
CN114957214A (zh) * 2022-06-22 2022-08-30 九江善水科技股份有限公司 一种氯虫苯甲酰胺中间体的制备方法

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3536809A (en) * 1969-02-17 1970-10-27 Alza Corp Medication method
US3598123A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
GB1363215A (en) * 1973-01-04 1974-08-14 Mullard Ltd Mechanical-electrical transducer
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4008719A (en) * 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
US5053595A (en) * 1982-12-01 1991-10-01 Metcal, Inc. Heat shrink sleeve with high mu material
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
JPH0680054B2 (ja) 1985-06-19 1994-10-12 吉富製薬株式会社 ピペリジン誘導体
US5316759A (en) * 1986-03-17 1994-05-31 Robert J. Schaap Agonist-antagonist combination to reduce the use of nicotine and other drugs
US5198459A (en) * 1987-07-11 1993-03-30 Sandoz Ltd. Use of 5HT-3 antagonists in preventing or reducing dependency on dependency-inducing agents
DE3822792C2 (de) * 1987-07-11 1997-11-27 Sandoz Ag Neue Verwendung von 5HT¶3¶-Antagonisten
US5073543A (en) * 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
IT1229203B (it) 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
US5120548A (en) * 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
US5075341A (en) * 1989-12-01 1991-12-24 The Mclean Hospital Corporation Treatment for cocaine abuse
US5733566A (en) * 1990-05-15 1998-03-31 Alkermes Controlled Therapeutics Inc. Ii Controlled release of antiparasitic agents in animals
CZ288351B6 (en) * 1990-06-07 2001-05-16 Astrazeneca Ab Nitrogenous heterocyclic compound, process of its preparation and use as well as a medicament containing thereof
FR2676734B1 (fr) * 1991-05-23 1995-05-19 Roussel Uclaf Nouveaux derives de la pyrimidine, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
US5698155A (en) * 1991-05-31 1997-12-16 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
US6204284B1 (en) * 1991-12-20 2001-03-20 American Cyanamid Company Use of 1-(substitutedphenyl)-3-azabicyclo[3.1.0]hexanes for the treatment of chemical dependencies
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5232934A (en) * 1992-07-17 1993-08-03 Warner-Lambert Co. Method for the treatment of psychomotor stimulant addiction
DE4234295A1 (de) * 1992-10-12 1994-04-14 Thomae Gmbh Dr K Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5591767A (en) * 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac
US5321012A (en) * 1993-01-28 1994-06-14 Virginia Commonwealth University Medical College Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance
IT1270594B (it) * 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
US5556837A (en) * 1994-08-01 1996-09-17 Regeneron Pharmaceuticals Inc. Methods for treating addictive disorders
US5762925A (en) * 1994-11-03 1998-06-09 Sagen; Jacqueline Preventing opiate tolerance by cellular implantation
ATE301457T1 (de) * 1995-06-12 2005-08-15 Searle & Co Mittel, enthaltend einen cyclooxygenase-2 inhibitor und einen 5-lipoxygenase inhibitor
US6063930A (en) * 1996-04-03 2000-05-16 Merck & Co., Inc. Substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
CA2274593A1 (en) * 1996-12-13 1998-06-18 Banyu Pharmaceutical Co., Ltd. Novel aminopyrazole derivatives
US6703362B1 (en) * 1997-05-15 2004-03-09 Cytogen Corporation Random peptides that bind to gastro-intestinal tract (GIT) transport receptors and related methods
JP4444493B2 (ja) * 1997-08-20 2010-03-31 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア カプサイシン受容体およびカプサイシン受容体関連ポリペプチドをコードする核酸配列ならびにその使用
EP0943683A1 (en) * 1998-03-10 1999-09-22 Smithkline Beecham Plc Human vanilloid receptor homologue Vanilrep1
US6098369A (en) * 1998-07-17 2000-08-08 Bodolay; William A. Apparatus for attaching a reclosable fastener to a flexible material
US6689780B1 (en) * 1998-12-23 2004-02-10 Eli Lilly And Company Heteroroaromatic amides as inhibitor of factor Xa
CA2361149A1 (en) * 1998-12-23 2000-07-06 Eli Lilly And Company Aromatic amides
ATE240316T1 (de) * 1998-12-23 2003-05-15 Lilly Co Eli Heteroaromatische amide als inhibitoren von faktor xa
GB9907097D0 (en) * 1999-03-26 1999-05-19 Novartis Ag Organic compounds
US6632815B2 (en) * 1999-09-17 2003-10-14 Millennium Pharmaceuticals, Inc. Inhibitors of factor Xa
EP1272187B1 (de) 2000-03-27 2008-07-30 Abbott GmbH & Co. KG Dopamin-d3-rezeptor-liganden zur behandlung von sucht
PT1285651E (pt) * 2000-04-28 2010-10-21 Takeda Pharmaceutical Antagonistas da hormona concentradora da melanina
AR028782A1 (es) * 2000-07-05 2003-05-21 Taisho Pharmaceutical Co Ltd Derivados heterociclicos tetrahidropiridino o piperidino
JP2003142681A (ja) 2001-10-31 2003-05-16 Sony Corp 絶縁ゲート型電界効果トランジスタを有する半導体装置
JP2003192673A (ja) 2001-12-27 2003-07-09 Bayer Ag ピペラジンカルボキシアミド誘導体
AU2003212882A1 (en) * 2002-02-01 2003-09-02 Euro-Celtique S.A. 2 - piperazine - pyridines useful for treating pain
ATE416168T1 (de) 2002-02-15 2008-12-15 Glaxo Group Ltd Modulatoren des vanilloidrezeptors
JP2006505570A (ja) * 2002-10-17 2006-02-16 アムジエン・インコーポレーテツド ベンズイミダゾール誘導体およびそれのバニロイド受容体リガンドとしての使用
US7067509B2 (en) * 2003-03-07 2006-06-27 Neurocrine Biosciences, Inc. Melanin-concentrating hormone receptor antagonists and compositions and methods related thereto
US20050014753A1 (en) 2003-04-04 2005-01-20 Irm Llc Novel compounds and compositions as protein kinase inhibitors
ATE556067T1 (de) * 2003-05-20 2012-05-15 Ajinomoto Kk Modulatoren des vanilloid rezeptors
AR044688A1 (es) * 2003-06-12 2005-09-21 Euro Celtique Sa Agentes terapeuticos utiles para el tratamiento del dolor
US20050009841A1 (en) * 2003-07-11 2005-01-13 Zheng Guo Zhu Novel amides useful for treating pain
US7129235B2 (en) * 2003-07-11 2006-10-31 Abbott Laboratories Amides useful for treating pain
EP1648878B9 (en) * 2003-07-24 2011-03-16 Euro-Celtique S.A. Piperidine compounds and pharmaceutical compositions containing them
ES2327684T3 (es) * 2003-07-24 2009-11-02 Euro-Celtique S.A. Compuestos heteroaril-tetrahidropiridilo utiles para el tratamiento o la prevencion del dolor.
CA2685121A1 (en) * 2007-04-27 2008-11-06 Purdue Pharma L.P. Therapeutic agents useful for treating pain

Similar Documents

Publication Publication Date Title
JP6506836B2 (ja) B型肝炎ウイルス感染症の処置および予防のための新規ピリダゾンおよびトリアジノン
JP2006513268A5 (ja) アンタゴニスト活性を有するベンゾアゾリルピペラジン誘導体
KR910004430B1 (ko) 5-피리딜-1,3-티아졸 유도체의 제조방법
JP2019510787A5 (enExample)
JP2005535731A5 (enExample)
JP2006528643A5 (enExample)
JP2002529532A5 (enExample)
CN1040324C (zh) 新的噻唑烷二酮及含有这些化合物的药剂
JP2005504789A5 (enExample)
RU96101139A (ru) Новые производные эритромицина, способ их получения и применение в качестве лекарственных средств
JP2022533069A5 (enExample)
JP2003503387A5 (enExample)
JP2003521542A (ja) チアゾリジンカルボン酸誘導体及び癌の治療におけるその利用
JP2002523371A (ja) ウイルス感染および関連疾患を治療または予防するための化合物、組成物および方法
JP2004517813A5 (enExample)
JP2006507355A5 (enExample)
CN105051017A (zh) 用于hbv组装效应剂的替代用途
TW200528097A (en) Novel thiazolidin-4-one derivatives
JP2010540593A5 (enExample)
JPWO2007126043A1 (ja) チアゾール環を含むカルボン酸誘導体の医薬用途
CN1011784B (zh) 制备抗过敏和抗支气管痉挛药n-二苯甲基二氮杂环烷基烷基n-酰苯胺的方法
CA2528920A1 (en) Cyclo(hetero)alkenyl compounds useful for treating pain
JP2009538309A5 (enExample)
JP2020504120A5 (enExample)
JP2006517201A5 (enExample)