JP2006510609A5 - - Google Patents

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Publication number
JP2006510609A5
JP2006510609A5 JP2004546967A JP2004546967A JP2006510609A5 JP 2006510609 A5 JP2006510609 A5 JP 2006510609A5 JP 2004546967 A JP2004546967 A JP 2004546967A JP 2004546967 A JP2004546967 A JP 2004546967A JP 2006510609 A5 JP2006510609 A5 JP 2006510609A5
Authority
JP
Japan
Prior art keywords
methanone
ylmethylphenyl
phenyl
isopropylpiperazin
dihydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2004546967A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006510609A (ja
JP4596918B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/033343 external-priority patent/WO2004037801A1/en
Publication of JP2006510609A publication Critical patent/JP2006510609A/ja
Publication of JP2006510609A5 publication Critical patent/JP2006510609A5/ja
Application granted granted Critical
Publication of JP4596918B2 publication Critical patent/JP4596918B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2004546967A 2002-10-23 2003-10-21 ピペラジニルおよびジアザパニルベンズアミドおよびベンズチオアミド Expired - Fee Related JP4596918B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42049502P 2002-10-23 2002-10-23
PCT/US2003/033343 WO2004037801A1 (en) 2002-10-23 2003-10-21 Piperazinyl and diazapanyl benzamides and benzthioamides

Publications (3)

Publication Number Publication Date
JP2006510609A JP2006510609A (ja) 2006-03-30
JP2006510609A5 true JP2006510609A5 (enExample) 2006-09-21
JP4596918B2 JP4596918B2 (ja) 2010-12-15

Family

ID=32176579

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004546967A Expired - Fee Related JP4596918B2 (ja) 2002-10-23 2003-10-21 ピペラジニルおよびジアザパニルベンズアミドおよびベンズチオアミド

Country Status (32)

Country Link
US (2) US7414047B2 (enExample)
EP (1) EP1558595B1 (enExample)
JP (1) JP4596918B2 (enExample)
KR (1) KR101067732B1 (enExample)
CN (1) CN100558718C (enExample)
AR (1) AR041697A1 (enExample)
AT (1) ATE449766T1 (enExample)
AU (1) AU2003301552B2 (enExample)
BR (1) BRPI0315644B8 (enExample)
CA (1) CA2504269C (enExample)
CR (1) CR7807A (enExample)
CY (1) CY1109924T1 (enExample)
DE (1) DE60330269D1 (enExample)
DK (1) DK1558595T3 (enExample)
EA (1) EA009860B1 (enExample)
EG (1) EG25097A (enExample)
ES (1) ES2335584T3 (enExample)
HR (1) HRP20050352B1 (enExample)
IL (1) IL168207A (enExample)
ME (1) ME00334B (enExample)
MX (2) MX339074B (enExample)
MY (1) MY140886A (enExample)
NO (1) NO330741B1 (enExample)
NZ (2) NZ576432A (enExample)
PL (1) PL215454B1 (enExample)
PT (1) PT1558595E (enExample)
RS (1) RS51681B (enExample)
SI (1) SI1558595T1 (enExample)
TW (1) TWI352594B (enExample)
UA (1) UA80573C2 (enExample)
WO (1) WO2004037801A1 (enExample)
ZA (1) ZA200504067B (enExample)

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ATE449766T1 (de) 2002-10-23 2009-12-15 Janssen Pharmaceutica Nv Piperazinyl- und diazapanylbenzamide und- benzothioamide
GB0324159D0 (en) * 2003-10-15 2003-11-19 Glaxo Group Ltd Novel compounds
JP2007531753A (ja) * 2004-03-31 2007-11-08 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 非イミダゾール系複素環式化合物
MXPA06011410A (es) 2004-03-31 2007-04-20 Johnson & Johnson Compuestos heterociclicos sin imidazol como moduladores de receptor de histamina h3.
KR101336106B1 (ko) * 2005-09-16 2013-12-05 얀센 파마슈티카 엔.브이. 히스타민 ｈ3 수용체의 조절제로서 사이클로프로필 아민
DK1951699T3 (da) * 2005-10-31 2013-01-14 Janssen Pharmaceutica Nv Fremgangsmåder til fremstilling af cyclopropylamidderivater
US7795426B2 (en) * 2005-10-31 2010-09-14 Janssen Pharmaceutica Nv Processes for the preparation of cyclopropyl-amide derivatives
EP2404911A1 (en) * 2005-10-31 2012-01-11 Janssen Pharmaceutica NV Novel processes for the preparation of piperazinyl and diazapanyl benzamide derivatives
RU2428423C2 (ru) * 2005-11-10 2011-09-10 Баниу Фармасьютикал Ко., Лтд. Азазамещенные спиропроизводные
MX339668B (es) * 2006-05-30 2016-06-02 Janssen Pharmaceutica N V * Compuestos de piridil amida sustituidos como moduladores del receptor h3 de la histamina.
CA2655604C (en) 2006-06-23 2016-08-09 Abbott Laboratories Cyclopropyl amine derivatives
US9108948B2 (en) 2006-06-23 2015-08-18 Abbvie Inc. Cyclopropyl amine derivatives
CN101511807A (zh) * 2006-06-29 2009-08-19 詹森药业有限公司 组胺h3受体的取代的苯甲酰胺调节剂
ES2620818T3 (es) * 2006-12-14 2017-06-29 Janssen Pharmaceutica N.V. Procedimiento para la preparación de derivados de piperazinil y diazepanil benzamida
WO2009030716A1 (en) * 2007-09-06 2009-03-12 Glaxo Group Limited Piperazine derivative having affinity for the histamine h3 receptor
AR068509A1 (es) * 2007-09-19 2009-11-18 Jerini Ag Antagosnistas del receptor de bradiquinina b1
CN105712977B (zh) 2007-11-20 2021-06-29 詹森药业有限公司 作为组胺h3受体调节剂的环烷基氧基吡啶化合物和杂环烷基氧基吡啶化合物
US20100130477A1 (en) * 2008-11-25 2010-05-27 Astrazeneca Ab Spirocyclobutyl Piperidine Derivatives
HRP20170776T1 (hr) * 2009-03-18 2017-08-11 Janssen Pharmaceutica N.V. Postupak za pripravu modulatora histaminskog h3 receptora
US9186353B2 (en) 2009-04-27 2015-11-17 Abbvie Inc. Treatment of osteoarthritis pain
US8853390B2 (en) 2010-09-16 2014-10-07 Abbvie Inc. Processes for preparing 1,2-substituted cyclopropyl derivatives
RU2700595C1 (ru) * 2019-07-30 2019-09-18 Общество с ограниченной ответственностью "Кью Эм Фарма" Производное 3,6,9-триазатрициклотетрадекана и его применение для лечения депрессии
EP4251148A1 (en) 2020-11-27 2023-10-04 Richter Gedeon Nyrt. Histamine h3 receptor antagonists/inverse agonists for the treatment of autism spectrum disorder

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ATE449766T1 (de) 2002-10-23 2009-12-15 Janssen Pharmaceutica Nv Piperazinyl- und diazapanylbenzamide und- benzothioamide
WO2005035534A1 (ja) 2003-10-08 2005-04-21 Ono Pharmaceutical Co., Ltd. 複素ビシクロ環および複素トリシクロ環化合物およびその医薬
GB0324159D0 (en) 2003-10-15 2003-11-19 Glaxo Group Ltd Novel compounds

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