|
CN101563324A
(zh)
|
2006-12-22 |
2009-10-21 |
弗·哈夫曼-拉罗切有限公司 |
螺-哌啶衍生物
|
|
AU2013201306B2
(en)
*
|
2007-03-12 |
2015-11-12 |
Glaxosmithkline Llc |
Phenyl Amino Pyrimidine Compounds and Uses Thereof
|
|
HUE029188T2
(en)
|
2007-03-12 |
2017-03-28 |
Ym Biosciences Australia Pty |
Phenylamino-pyrimidine compounds and their use
|
|
AU2016200866B2
(en)
*
|
2007-03-12 |
2017-06-22 |
Glaxosmithkline Llc |
Phenyl amino pyrimidine compounds and uses thereof
|
|
US8507511B2
(en)
*
|
2007-04-24 |
2013-08-13 |
Ingenium Pharmaceuticals Gmbh |
Inhibitors of protein kinases
|
|
EP2200436B1
(en)
|
2007-09-04 |
2015-01-21 |
The Scripps Research Institute |
Substituted pyrimidinyl-amines as protein kinase inhibitors
|
|
ATE535515T1
(de)
|
2008-01-11 |
2011-12-15 |
Hoffmann La Roche |
Modulatoren für amyloid beta
|
|
KR101247840B1
(ko)
*
|
2008-02-22 |
2013-03-26 |
에프. 호프만-라 로슈 아게 |
아밀로이드 베타 조절제
|
|
JP5502089B2
(ja)
|
2008-10-09 |
2014-05-28 |
エフ.ホフマン−ラ ロシュ アーゲー |
アミロイドβのモジュレーター
|
|
CN102209537A
(zh)
|
2008-11-10 |
2011-10-05 |
弗·哈夫曼-拉罗切有限公司 |
杂环γ分泌酶调节剂
|
|
KR20120114224A
(ko)
*
|
2009-10-12 |
2012-10-16 |
마이렉시스 인코포레이티드 |
Ikk 엡실론 및/또는 tbk1의 억제제로서의 아미노-피리미딘 화합물
|
|
EP2512246B1
(en)
|
2009-12-17 |
2015-09-30 |
Merck Sharp & Dohme Corp. |
Aminopyrimidines as syk inhibitors
|
|
AU2010331927B2
(en)
|
2009-12-17 |
2013-10-10 |
Merck Canada Inc. |
Aminopyrimidines as Syk inhibitors
|
|
US8486967B2
(en)
|
2010-02-17 |
2013-07-16 |
Hoffmann-La Roche Inc. |
Heteroaryl substituted piperidines
|
|
EP2593447B1
(de)
|
2010-07-15 |
2016-08-17 |
Bayer Intellectual Property GmbH |
3-pyridyl-heteroarylcarboxamidverbindungen als schädlingsbekämpfungsmittel
|
|
GB201012105D0
(en)
|
2010-07-19 |
2010-09-01 |
Domainex Ltd |
Novel pyrimidine compounds
|
|
US9376709B2
(en)
|
2010-07-26 |
2016-06-28 |
Biomatrica, Inc. |
Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures
|
|
EP2598661B1
(en)
|
2010-07-26 |
2017-09-27 |
Biomatrica, INC. |
Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
|
|
BR112013009823A2
(pt)
|
2010-10-22 |
2016-07-05 |
Bayer Ip Gmbh |
novos compostos heterocíclicos como pesticidas
|
|
WO2012088266A2
(en)
|
2010-12-22 |
2012-06-28 |
Incyte Corporation |
Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
|
|
US9133187B2
(en)
|
2011-02-28 |
2015-09-15 |
Array Biopharma Inc. |
Serine/threonine kinase inhibitors
|
|
EP2694486B1
(en)
|
2011-04-01 |
2018-01-10 |
University of Utah Research Foundation |
Substituted n-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase btk inhibitors
|
|
KR20140048873A
(ko)
*
|
2011-04-12 |
2014-04-24 |
알츠하이머즈 인스티튜트 오브 아메리카, 인크. |
Ikk-관련 키나제 엡실론 및 tank 결합 키나제 1 억제제의 조성물 및 치료학적 용도
|
|
AU2012244745A1
(en)
|
2011-04-19 |
2013-09-19 |
Bayer Intellectual Property Gmbh |
Substituted 4-Aryl-N-phenyl-1,3,5-triazin-2-amines
|
|
AU2012253885A1
(en)
|
2011-05-10 |
2013-10-31 |
Merck Sharp & Dohme Corp. |
Aminopyrimidines as Syk inhibitors
|
|
WO2012154518A1
(en)
|
2011-05-10 |
2012-11-15 |
Merck Sharp & Dohme Corp. |
Bipyridylaminopyridines as syk inhibitors
|
|
CA2834062A1
(en)
|
2011-05-10 |
2012-11-15 |
Merck Sharp & Dohme Corp. |
Pyridyl aminopyridines as syk inhibitors
|
|
TW201636330A
(zh)
|
2011-05-24 |
2016-10-16 |
拜耳知識產權公司 |
含有硫醯亞胺基團之4-芳基-n-苯基-1,3,5-三氮雜苯-2-胺
|
|
ES2729947T3
(es)
*
|
2011-07-12 |
2019-11-07 |
Dow Agrosciences Llc |
Composiciones pesticidas y procedimientos relacionados con las mismas
|
|
ES2552989T3
(es)
|
2011-08-04 |
2015-12-03 |
Array Biopharma, Inc. |
Compuestos de quinazolina como inhibidores de la cinasa de serina / treonina
|
|
DE102011112978A1
(de)
|
2011-09-09 |
2013-03-14 |
Merck Patent Gmbh |
Benzonitrilderivate
|
|
CN103930399B
(zh)
|
2011-09-16 |
2016-03-16 |
拜耳知识产权有限责任公司 |
包含亚氨基亚磺酰基的二取代的5-氟嘧啶衍生物
|
|
CN103917527B
(zh)
|
2011-09-16 |
2017-05-31 |
拜耳知识产权有限责任公司 |
二取代的5‑氟‑嘧啶
|
|
PE20150666A1
(es)
|
2012-03-01 |
2015-05-06 |
Array Biopharma Inc |
Inhibidores de serina/treonina cinasa
|
|
CA2876689C
(en)
|
2012-06-13 |
2022-04-26 |
Incyte Corporation |
Substituted tricyclic compounds as fgfr inhibitors
|
|
US8809359B2
(en)
|
2012-06-29 |
2014-08-19 |
Ym Biosciences Australia Pty Ltd |
Phenyl amino pyrimidine bicyclic compounds and uses thereof
|
|
US9388185B2
(en)
|
2012-08-10 |
2016-07-12 |
Incyte Holdings Corporation |
Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
|
|
CA2882750A1
(en)
|
2012-08-27 |
2014-03-06 |
Jim Blake |
Serine/threonine kinase inhibitors for the treatment of hyperproliferative|diseases
|
|
KR102194611B1
(ko)
*
|
2012-10-04 |
2020-12-23 |
유니버시티 오브 유타 리서치 파운데이션 |
티로신 수용체 키나아제 btk 억제제로서 치환된 n-(3-(피리미딘-4-일)페닐)아크릴아미드 유사체
|
|
JP6313772B2
(ja)
*
|
2012-10-04 |
2018-04-18 |
ユニヴァーシティー オブ ユタ リサーチ ファウンデーション |
チロシン受容体キナーゼbtk阻害剤である置換n−(3−(ピリミジン−4−イル)フェニル)アクリルアミド類似体
|
|
CN105102434A
(zh)
|
2012-10-18 |
2015-11-25 |
拜耳药业股份公司 |
含砜基团的4-(邻)-氟苯基-5-氟嘧啶-2-基胺
|
|
HK1209414A1
(en)
|
2012-10-18 |
2016-04-01 |
Bayer Pharma Aktiengesellschaft |
5-fluoro-n-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfone group
|
|
TW201418243A
(zh)
|
2012-11-15 |
2014-05-16 |
Bayer Pharma AG |
含有磺醯亞胺基團之n-(吡啶-2-基)嘧啶-4-胺衍生物
|
|
US9266892B2
(en)
|
2012-12-19 |
2016-02-23 |
Incyte Holdings Corporation |
Fused pyrazoles as FGFR inhibitors
|
|
US9725703B2
(en)
|
2012-12-20 |
2017-08-08 |
Biomatrica, Inc. |
Formulations and methods for stabilizing PCR reagents
|
|
GB201303109D0
(en)
*
|
2013-02-21 |
2013-04-10 |
Domainex Ltd |
Novel pyrimidine compounds
|
|
PH12015502383B1
(en)
|
2013-04-19 |
2023-02-03 |
Incyte Holdings Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
US20160135446A1
(en)
|
2013-06-13 |
2016-05-19 |
Biomatrica, Inc. |
Cell stabilization
|
|
WO2015191632A1
(en)
|
2014-06-10 |
2015-12-17 |
Biomatrica, Inc. |
Stabilization of thrombocytes at ambient temperatures
|
|
TWI681954B
(zh)
|
2014-06-12 |
2020-01-11 |
美商西爾拉癌症醫學公司 |
N-(氰基甲基)-4-(2-(4-𠰌啉基苯基胺基)嘧啶-4-基)苯甲醯胺
|
|
CA2964683A1
(en)
|
2014-10-16 |
2016-04-21 |
Bayer Pharma Aktiengesellschaft |
Fluorinated benzofuranyl-pyrimidine derivatives containing a sulfone group
|
|
US10851105B2
(en)
|
2014-10-22 |
2020-12-01 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
US9580423B2
(en)
|
2015-02-20 |
2017-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
CA2976790C
(en)
|
2015-02-20 |
2024-02-27 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
JP2018509439A
(ja)
|
2015-03-24 |
2018-04-05 |
バイエル ファーマ アクチエンゲゼルシャフト |
多発性骨髄腫を治療するための4−(4−フルオロ−2−メトキシフェニル)−n−{3−[(s−メチルスルホンイミドイル)メチル]フェニル}−1,3,5−トリアジン−2−アミンの使用
|
|
JP2018509440A
(ja)
|
2015-03-24 |
2018-04-05 |
バイエル ファーマ アクチエンゲゼルシャフト |
リンパ腫の治療のための4−(4−フルオロ−2−メトキシフェニル)−n−{3−[(s−メチルスルホンイミドイル)メチル]フェニル}−1,3,5−トリアジン−2−アミンの使用
|
|
WO2016150902A1
(en)
|
2015-03-24 |
2016-09-29 |
Bayer Pharma Aktiengesellschaft |
Use of 4-(4-fluoro-2-methoxyphenyl)-n-{3-[(s-methylsulfonimidoyl)methyl]phenyl}-1,3,5-triazin-2-amine for treating gastric cancers
|
|
WO2017007755A1
(en)
|
2015-07-06 |
2017-01-12 |
Rodin Therapeutics, Inc. |
Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase
|
|
HUE057041T2
(hu)
|
2015-07-06 |
2022-04-28 |
Alkermes Inc |
Hiszton deacetiláz hetero-halogén gátlói
|
|
JP6847099B2
(ja)
|
2015-09-29 |
2021-03-24 |
バイエル ファーマ アクチエンゲゼルシャフト |
新規な大環状スルホンジイミン化合物
|
|
ES2819869T3
(es)
|
2015-10-08 |
2021-04-19 |
Bayer Pharma AG |
Nuevos compuestos macrocíclicos modificados
|
|
WO2017060322A2
(en)
|
2015-10-10 |
2017-04-13 |
Bayer Pharma Aktiengesellschaft |
Ptefb-inhibitor-adc
|
|
FI3362445T3
(fi)
|
2015-10-12 |
2023-03-21 |
Chong Kun Dang Pharmaceutical Corp |
Oksadiatsoliamiinijohdannaisyhdisteitä histonideasetylaasi 6:n inhibiittoreina ja niitä käsittävä farmaseuttinen koostumus
|
|
ES2946184T3
(es)
|
2015-12-08 |
2023-07-13 |
Biomatrica Inc |
Reducción de la velocidad de eritrosedimentación
|
|
CN110818690B
(zh)
|
2016-07-26 |
2021-08-10 |
深圳市塔吉瑞生物医药有限公司 |
用于抑制蛋白酪氨酸激酶活性的氨基嘧啶类化合物
|
|
US20190231751A1
(en)
*
|
2016-09-12 |
2019-08-01 |
Imago Pharmaceuticals, Inc. |
Treatment of fibrotic disorders with jun n-terminal kinase inhibitors
|
|
HRP20220223T1
(hr)
|
2017-01-11 |
2022-04-29 |
Alkermes, Inc. |
Biciklički inhibitori histon deacetilaze
|
|
US20190381125A1
(en)
*
|
2017-02-15 |
2019-12-19 |
University Of Massachusetts |
Methods of Treating Angiogenesis-Related Disorders Using JNK3 Inhibitors
|
|
GB201702947D0
(en)
|
2017-02-23 |
2017-04-12 |
Domainex Ltd |
Novel compounds
|
|
CA3057891A1
(en)
|
2017-03-28 |
2018-10-04 |
Bayer Aktiengesellschaft |
Novel ptefb inhibiting macrocyclic compounds
|
|
EP3601253B1
(en)
|
2017-03-28 |
2021-09-15 |
Bayer Aktiengesellschaft |
Novel ptefb inhibiting macrocyclic compounds
|
|
GB201705263D0
(en)
*
|
2017-03-31 |
2017-05-17 |
Probiodrug Ag |
Novel inhibitors
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
US11225475B2
(en)
|
2017-08-07 |
2022-01-18 |
Alkermes, Inc. |
Substituted pyridines as inhibitors of histone deacetylase
|
|
US11440899B2
(en)
|
2017-10-17 |
2022-09-13 |
Merck Patent Gmbh |
Pyrimidine TBK/IKKe inhibitor compounds and uses thereof
|
|
SG11202003407VA
(en)
*
|
2017-10-17 |
2020-05-28 |
Merck Patent Gmbh |
PYRIMIDINE TBK/IKKe INHIBITOR COMPOUNDS AND USES THEREOF
|
|
CA3086765A1
(en)
|
2017-12-28 |
2019-07-04 |
Tract Pharmaceuticals, Inc. |
Stem cell culture systems for columnar epithelial stem cells, and uses related thereto
|
|
US11701347B2
(en)
|
2018-02-13 |
2023-07-18 |
Bayer Aktiengesellschaft |
Use of 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl}pyridin-2-amine for treating diffuse large B-cell lymphoma
|
|
RS66310B1
(sr)
|
2018-05-04 |
2025-01-31 |
Incyte Corp |
Čvrsti oblici inhibitora fgfr i procesi za njegovu pripremu
|
|
KR102956194B1
(ko)
|
2018-05-04 |
2026-04-23 |
인사이트 코포레이션 |
Fgfr 억제제의 염
|
|
JP7447098B2
(ja)
*
|
2018-09-25 |
2024-03-11 |
カーデュリオン・ファーマシューティカルズ・インコーポレイテッド |
アミノピリミジン化合物
|
|
WO2020068846A1
(en)
*
|
2018-09-25 |
2020-04-02 |
Heterocyclic Compound |
Heterocyclic compound
|
|
PY19106549A
(es)
*
|
2018-12-21 |
2021-07-13 |
Bayer Ag |
1,3,4-oxadiazoles y derivados de éstos como nuevos agentes fungicidas
|
|
WO2020185532A1
(en)
|
2019-03-08 |
2020-09-17 |
Incyte Corporation |
Methods of treating cancer with an fgfr inhibitor
|
|
WO2021007269A1
(en)
|
2019-07-09 |
2021-01-14 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
US20220348590A1
(en)
*
|
2019-09-13 |
2022-11-03 |
The Board Institute, Inc. |
Cyclooxygenase-2 inhibitors and uses thereof
|
|
US12122767B2
(en)
|
2019-10-01 |
2024-10-22 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
GEP20247679B
(en)
|
2019-10-14 |
2024-10-10 |
Incyte Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
WO2021113479A1
(en)
|
2019-12-04 |
2021-06-10 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
MX2022006691A
(es)
|
2019-12-04 |
2022-09-19 |
Incyte Corp |
Derivados de un inhibidor de receptores del factor de crecimiento de fibroblastos (fgfr).
|
|
US12012409B2
(en)
|
2020-01-15 |
2024-06-18 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
JP7587113B2
(ja)
*
|
2020-09-29 |
2024-11-20 |
日亜化学工業株式会社 |
異方性磁性粉末の製造方法および異方性磁性粉末
|
|
EP4323405A1
(en)
|
2021-04-12 |
2024-02-21 |
Incyte Corporation |
Combination therapy comprising an fgfr inhibitor and a nectin-4 targeting agent
|
|
TW202313610A
(zh)
|
2021-06-09 |
2023-04-01 |
美商英塞特公司 |
作為fgfr抑制劑之三環雜環
|
|
CA3220274A1
(en)
|
2021-06-09 |
2022-12-15 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
TW202329937A
(zh)
|
2021-12-03 |
2023-08-01 |
美商英塞特公司 |
雙環胺ck12抑制劑
|
|
US12084453B2
(en)
|
2021-12-10 |
2024-09-10 |
Incyte Corporation |
Bicyclic amines as CDK12 inhibitors
|
|
CN121487932A
(zh)
*
|
2024-05-13 |
2026-02-06 |
阿诺医药 (新加坡) 有限公司 |
一种内酰胺结构cdk抑制剂化合物
|