JP2006501187A5 - - Google Patents

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Publication number
JP2006501187A5
JP2006501187A5 JP2004520018A JP2004520018A JP2006501187A5 JP 2006501187 A5 JP2006501187 A5 JP 2006501187A5 JP 2004520018 A JP2004520018 A JP 2004520018A JP 2004520018 A JP2004520018 A JP 2004520018A JP 2006501187 A5 JP2006501187 A5 JP 2006501187A5
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JP
Japan
Prior art keywords
compound
inhibitors
agent
alkyl
structural formula
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Application number
JP2004520018A
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English (en)
Japanese (ja)
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JP2006501187A (ja
JP4541883B2 (ja
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Priority claimed from PCT/US2003/021331 external-priority patent/WO2004004655A2/en
Publication of JP2006501187A publication Critical patent/JP2006501187A/ja
Publication of JP2006501187A5 publication Critical patent/JP2006501187A5/ja
Application granted granted Critical
Publication of JP4541883B2 publication Critical patent/JP4541883B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2004520018A 2002-07-09 2003-07-08 抗糖尿病薬および抗肥満症薬として有用な置換へテロ環誘導体、並びに方法 Expired - Fee Related JP4541883B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39455302P 2002-07-09 2002-07-09
PCT/US2003/021331 WO2004004655A2 (en) 2002-07-09 2003-07-08 Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method

Publications (3)

Publication Number Publication Date
JP2006501187A JP2006501187A (ja) 2006-01-12
JP2006501187A5 true JP2006501187A5 (https=) 2006-08-31
JP4541883B2 JP4541883B2 (ja) 2010-09-08

Family

ID=30115733

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004520018A Expired - Fee Related JP4541883B2 (ja) 2002-07-09 2003-07-08 抗糖尿病薬および抗肥満症薬として有用な置換へテロ環誘導体、並びに方法

Country Status (23)

Country Link
US (2) US6875782B2 (https=)
EP (1) EP1531810B1 (https=)
JP (1) JP4541883B2 (https=)
KR (1) KR101120337B1 (https=)
CN (1) CN1665500A (https=)
AT (1) ATE543497T1 (https=)
AU (1) AU2003248861B2 (https=)
BR (1) BR0312503A (https=)
CA (1) CA2490972C (https=)
ES (1) ES2380319T3 (https=)
GE (1) GEP20084475B (https=)
HR (1) HRP20050001A2 (https=)
IL (1) IL165809A (https=)
IS (1) IS7629A (https=)
MX (1) MXPA05000279A (https=)
NO (1) NO329328B1 (https=)
NZ (1) NZ537251A (https=)
PL (1) PL375230A1 (https=)
RS (1) RS20050002A (https=)
RU (1) RU2325381C2 (https=)
UA (1) UA79296C2 (https=)
WO (1) WO2004004655A2 (https=)
ZA (1) ZA200500029B (https=)

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FR2861300B1 (fr) * 2003-10-24 2008-07-11 Sanofi Synthelabo Utilisation d'un derive du pyrazole, pour la preparation de medicaments utiles dans la prevention et le traitement du syndrome metabolique
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WO2006128058A2 (en) 2005-05-26 2006-11-30 Metabasis Therapeutics, Inc. Thyromimetics for the treatment of fatty liver diseases
CN1882327A (zh) * 2003-11-19 2006-12-20 症变治疗公司 含磷的新的拟甲状腺素药
US7932268B2 (en) 2004-03-05 2011-04-26 The Trustees Of The University Of Pennsylvania Methods for treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia while minimizing side effects
US20060014785A1 (en) * 2004-05-25 2006-01-19 Metabolex, Inc. Bicyclic, substituted triazoles as modulators of ppar and methods of their preparation
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WO2006128056A2 (en) * 2005-05-26 2006-11-30 Metabasis Therapeutics, Inc. Novel phosphinic acid-containing thyromimetics
FR2889191A1 (fr) * 2005-07-28 2007-02-02 Cerep Sa Composes derives de 5-benzylidene imidazolidine 2,4-dione et leur utilisation en tant qu'antagonistes de mchr-1
GEP20135838B (en) 2005-09-14 2013-06-10 Takeda Pharmaceutical Dipeptidyl peptidase inhibitors usage at diabetes treatment
CN101360723A (zh) 2005-09-16 2009-02-04 武田药品工业株式会社 制备嘧啶二酮衍生物的方法
EP1951220A2 (en) * 2005-10-18 2008-08-06 Aegerion Pharmaceuticals Compositions for lowering serum cholesterol and/or triglycerides
JP2009538892A (ja) * 2006-05-30 2009-11-12 アストラゼネカ アクチボラグ アセチル補酵素ａジアシルグリセロールアシルトランスフェラーゼの阻害薬としての置換５−フェニルアミノ−１，３，４−オキサジアゾール−２−イルカルボニルアミノ−４−フェノキシ−シクロヘキサンカルボン酸
WO2007138304A1 (en) * 2006-05-30 2007-12-06 Astrazeneca Ab 1, 3, 4 -oxadiazole derivatives as dgat1 inhibitors
US20080009534A1 (en) * 2006-07-07 2008-01-10 Bristol-Myers Squibb Company Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
US8324383B2 (en) 2006-09-13 2012-12-04 Takeda Pharmaceutical Company Limited Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
US8217025B2 (en) * 2006-11-17 2012-07-10 Harbor Therapeutics, Inc. Drug screening and treatment methods
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