JP2006500949A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006500949A5 JP2006500949A5 JP2004541231A JP2004541231A JP2006500949A5 JP 2006500949 A5 JP2006500949 A5 JP 2006500949A5 JP 2004541231 A JP2004541231 A JP 2004541231A JP 2004541231 A JP2004541231 A JP 2004541231A JP 2006500949 A5 JP2006500949 A5 JP 2006500949A5
- Authority
- JP
- Japan
- Prior art keywords
- nsc
- lung cancer
- small cell
- cell lung
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 18
- 150000001875 compounds Chemical class 0.000 claims 17
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 14
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 12
- 229920001184 polypeptide Polymers 0.000 claims 11
- 102000004196 processed proteins & peptides Human genes 0.000 claims 11
- 108090000765 processed proteins & peptides Proteins 0.000 claims 11
- 210000004027 cell Anatomy 0.000 claims 7
- 230000002265 prevention Effects 0.000 claims 7
- 108091033319 polynucleotide Proteins 0.000 claims 5
- 239000002157 polynucleotide Substances 0.000 claims 5
- 102000040430 polynucleotide Human genes 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 230000004071 biological effect Effects 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 238000012216 screening Methods 0.000 claims 4
- 108700008625 Reporter Genes Proteins 0.000 claims 3
- 108020004459 Small interfering RNA Proteins 0.000 claims 3
- 230000000692 anti-sense effect Effects 0.000 claims 3
- 238000001514 detection method Methods 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 3
- 230000005809 anti-tumor immunity Effects 0.000 claims 2
- 239000012472 biological sample Substances 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 230000001105 regulatory effect Effects 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 230000002103 transcriptional effect Effects 0.000 claims 2
- 206010036790 Productive cough Diseases 0.000 claims 1
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 1
- 230000027455 binding Effects 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 230000004663 cell proliferation Effects 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 230000007423 decrease Effects 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 230000000144 pharmacologic effect Effects 0.000 claims 1
- 210000003802 sputum Anatomy 0.000 claims 1
- 208000024794 sputum Diseases 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41467302P | 2002-09-30 | 2002-09-30 | |
| US45137403P | 2003-02-28 | 2003-02-28 | |
| US46610003P | 2003-04-28 | 2003-04-28 | |
| PCT/JP2003/012072 WO2004031413A2 (en) | 2002-09-30 | 2003-09-22 | Method for diagnosing non-small cell lung cancers |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009138122A Division JP4921522B2 (ja) | 2002-09-30 | 2009-06-09 | 非小細胞肺癌の診断のための方法 |
| JP2009231138A Division JP2010042016A (ja) | 2002-09-30 | 2009-10-05 | 非小細胞肺癌の診断のための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006500949A JP2006500949A (ja) | 2006-01-12 |
| JP2006500949A5 true JP2006500949A5 (enExample) | 2006-11-02 |
| JP4425141B2 JP4425141B2 (ja) | 2010-03-03 |
Family
ID=32074369
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004541231A Expired - Fee Related JP4425141B2 (ja) | 2002-09-30 | 2003-09-22 | 非小細胞肺癌の診断のための方法 |
| JP2009138122A Expired - Fee Related JP4921522B2 (ja) | 2002-09-30 | 2009-06-09 | 非小細胞肺癌の診断のための方法 |
| JP2009231138A Pending JP2010042016A (ja) | 2002-09-30 | 2009-10-05 | 非小細胞肺癌の診断のための方法 |
| JP2012003039A Pending JP2012125247A (ja) | 2002-09-30 | 2012-01-11 | 非小細胞肺癌の診断のための方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009138122A Expired - Fee Related JP4921522B2 (ja) | 2002-09-30 | 2009-06-09 | 非小細胞肺癌の診断のための方法 |
| JP2009231138A Pending JP2010042016A (ja) | 2002-09-30 | 2009-10-05 | 非小細胞肺癌の診断のための方法 |
| JP2012003039A Pending JP2012125247A (ja) | 2002-09-30 | 2012-01-11 | 非小細胞肺癌の診断のための方法 |
Country Status (8)
| Country | Link |
|---|---|
| EP (30) | EP2270224A3 (enExample) |
| JP (4) | JP4425141B2 (enExample) |
| KR (2) | KR101075158B1 (enExample) |
| AT (1) | ATE541053T1 (enExample) |
| AU (1) | AU2003272088A1 (enExample) |
| CA (1) | CA2500151A1 (enExample) |
| TW (1) | TW200413725A (enExample) |
| WO (1) | WO2004031413A2 (enExample) |
Families Citing this family (96)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5300469A (en) * | 1992-12-08 | 1994-04-05 | Engelhard Corporation | Composition for passivating vanadium in catalytic cracking and preparation thereof |
| US8048629B2 (en) * | 1996-03-15 | 2011-11-01 | The Penn State Research Foundation | Detection of extracellular tumor-associated nucleic acid in blood plasma or serum |
| EP1576131A4 (en) * | 2002-08-15 | 2008-08-13 | Genzyme Corp | EXPRESSION PATTERN IN BRAIN DENTHELIC CELLS |
| CA2512337A1 (en) * | 2003-01-03 | 2004-07-29 | Gencia Corporation | Sirna mediated post-transcriptional gene silencing of genes involved in alopecia |
| US20050112622A1 (en) * | 2003-08-11 | 2005-05-26 | Ring Brian Z. | Reagents and methods for use in cancer diagnosis, classification and therapy |
| US20050186577A1 (en) | 2004-02-20 | 2005-08-25 | Yixin Wang | Breast cancer prognostics |
| JP2007530921A (ja) * | 2004-03-24 | 2007-11-01 | オンコセラピー・サイエンス株式会社 | 非小細胞肺癌に対する腫瘍マーカーおよび治療標的としてのａｄａｍ８ |
| JP4658936B2 (ja) * | 2004-03-24 | 2011-03-23 | オンコセラピー・サイエンス株式会社 | 肺癌を治療するための組成物および方法 |
| ATE483979T1 (de) * | 2004-08-10 | 2010-10-15 | Oncotherapy Science Inc | Gen anln in verbindung mit nicht-kleinzelligem lungenkrebs und seine wechselwirkungen mit rhoa |
| DE602005025231D1 (de) * | 2004-08-10 | 2011-01-20 | Oncotherapy Science Inc | Gene und polypeptide in verbindung mit brustkrebserkrankungen |
| DE602005023329D1 (de) * | 2004-09-24 | 2010-10-14 | Oncotherapy Science Inc | VERFAHREN ZUR DIAGNOSE NICHT-KLEINZELLIGER LUNGENKARZINOME ÜBER DIE tRNA-DIHYDROURIDIN-SYNTHASEAKTIVITÄT VON URLC8 |
| EP1812796B1 (en) * | 2004-10-19 | 2009-12-09 | Oncotherapy Science, Inc. | Pkp3 oncogene as a prognostic indicator for lung adenocarcinoma |
| WO2006056080A1 (en) * | 2004-11-29 | 2006-06-01 | Diagnocure Inc. | Gpx2 a specific and sensitive target for lung cancer diagnosis, prognosis and/or theranosis |
| JP2008523816A (ja) * | 2004-12-15 | 2008-07-10 | ベス イスラエル ディーコネス メディカル センター | 妊娠合併症の診断および処置に有用な核酸およびポリペプチド |
| EP2295601A1 (en) | 2005-02-10 | 2011-03-16 | Oncotherapy Science, Inc. | Method of diagnosing bladder cancer |
| EP1853703B1 (en) * | 2005-02-25 | 2011-04-13 | Oncotherapy Science, Inc. | Peptide vaccines for lung cancers expressing ttk polypeptides |
| EP1854473A1 (en) * | 2005-03-03 | 2007-11-14 | Takeda Pharmaceutical Company Limited | Preventive/therapeutic agent for cancer |
| WO2006105642A1 (en) * | 2005-04-05 | 2006-10-12 | British Columbia Cancer Agency | Biomarkers for the detection of lung cancer and uses thereof |
| JP2008539693A (ja) * | 2005-05-12 | 2008-11-20 | オンコセラピー・サイエンス株式会社 | 抗ｄｓｃ２抗体のエフェクター機能を用いて細胞を障害する方法 |
| US8053183B2 (en) | 2005-07-27 | 2011-11-08 | Oncotherapy Science, Inc. | Method of diagnosing esophageal cancer |
| DE102005052384B4 (de) * | 2005-10-31 | 2009-09-24 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur Erkennung, Markierung und Behandlung von epithelialen Lungentumorzellen sowie Mittel zur Durchführung des Verfahrens |
| KR100759288B1 (ko) * | 2005-11-14 | 2007-09-17 | 가톨릭대학교 산학협력단 | 비교유전자보합법을 이용한 폐암 및 폐암의 하부유형 진단방법 |
| US8138167B2 (en) | 2006-02-10 | 2012-03-20 | Oncotherapy Science, Inc. | Methods for treating lung cancers |
| EP2018440A1 (en) * | 2006-04-20 | 2009-01-28 | Oncotherapy Science, Inc. | NMU-GHSR1b/NTSR1 ONCOGENIC SIGNALING PATHWAY AS A THERAPEUTIC TARGET FOR LUNG CANCER |
| WO2008014951A1 (en) * | 2006-08-01 | 2008-02-07 | Roche Diagnostics Gmbh | Use of nnmt as a marker for lung cancer |
| WO2008020653A1 (en) * | 2006-08-18 | 2008-02-21 | Oncotherapy Science, Inc. | Use of holliday junction-recognizing protein related to cancer |
| US7851144B2 (en) | 2006-08-18 | 2010-12-14 | The University Of Washington | Compositions and methods for detecting cancer |
| EP2059610A1 (en) * | 2006-08-18 | 2009-05-20 | Oncotherapy Science, Inc. | Imp-1 oncogene as a therapeutic target and prognostic indicator for lung cancer |
| EP2061900A2 (en) | 2006-08-25 | 2009-05-27 | Oncotherapy Science, Inc. | Prognostic markers and therapeutic targets for lung cancer |
| US20080145313A1 (en) * | 2006-08-30 | 2008-06-19 | Genesis Research & Development Corporation Limited | Compositions and Methods for the Treatment and Prevention of Neoplastic Disorders |
| BRPI0717651A2 (pt) | 2006-10-17 | 2013-12-24 | Oncotherapy Science Inc | Vacinas de peptídeo para cânceres que expressam polipeptídeos mphosph1 ou depdc1 |
| TW200831673A (en) | 2006-12-13 | 2008-08-01 | Oncotherapy Science Inc | TTK as tumor marker and therapeutic target for lung cancer |
| KR100846354B1 (ko) * | 2007-03-21 | 2008-07-15 | (주) 프로탄바이오 | 혈청 당단백질부터 분리한 폐암 진단용 마커 |
| WO2008120812A1 (en) * | 2007-03-30 | 2008-10-09 | Oncotherapy Science, Inc. | Screening and therapeutic method for nsclc targeting the cdca8-aurkb complex |
| WO2008151110A2 (en) * | 2007-06-01 | 2008-12-11 | The University Of North Carolina At Chapel Hill | Molecular diagnosis and typing of lung cancer variants |
| WO2009016691A1 (en) * | 2007-07-30 | 2009-02-05 | Oncotherapy Science, Inc. | Cancer associated gene ly6k |
| JP5555952B2 (ja) | 2007-08-20 | 2014-07-23 | オンコセラピー・サイエンス株式会社 | Ｆｏｘｍ１ペプチドおよびこれを含む薬剤 |
| MX2010002018A (es) | 2007-08-20 | 2010-05-27 | Oncotherapy Science Inc | Peptido de cdh3 y agente medicinal que comprende al mismo. |
| MX2010002001A (es) * | 2007-08-20 | 2010-03-11 | Oncotherapy Science Inc | Peptido cdca1 y agente farmaceutico que comprende elmismo. |
| US8541183B2 (en) | 2007-09-11 | 2013-09-24 | Cancer Prevention And Cure, Ltd. | Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof |
| WO2009063970A1 (ja) | 2007-11-14 | 2009-05-22 | Forerunner Pharma Research Co., Ltd. | 抗gpr49抗体を用いる癌の診断および治療 |
| TWI526219B (zh) | 2008-06-19 | 2016-03-21 | 腫瘤療法 科學股份有限公司 | Ｃｄｃａ１抗原決定位胜肽及含此胜肽的疫苗 |
| JP5593560B2 (ja) | 2008-06-30 | 2014-09-24 | オンコセラピー・サイエンス株式会社 | 放射性同位体標識で標識された抗ｃｄｈ３抗体およびその使用 |
| TWI466680B (zh) | 2008-08-01 | 2015-01-01 | Oncotherapy Science Inc | Ｍｅｌｋ抗原決定位胜肽及含此胜肽的疫苗 |
| TWI580431B (zh) | 2008-08-19 | 2017-05-01 | 腫瘤療法 科學股份有限公司 | Ｈｉｇ２與ｕｒｌｃ１０抗原決定位胜肽以及含此胜肽之疫苗 |
| TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
| WO2010023837A1 (en) * | 2008-08-27 | 2010-03-04 | Oncotherapy Science, Inc. | Breast cancer related gene rqcd1 |
| WO2010023856A1 (en) * | 2008-08-27 | 2010-03-04 | Oncotherapy Science, Inc. | Pancreatic cancer related gene ttll4 |
| BRPI0917350A2 (pt) * | 2008-08-28 | 2015-08-11 | Oncotherapy Science Inc | Oip5 como um gene alvo para terapia e diagnose de câncer |
| KR101064561B1 (ko) * | 2008-09-24 | 2011-09-14 | 고려대학교 산학협력단 | 폐선암 수술 후 초기 재발 예측용 바이오마커 |
| WO2010067487A1 (en) * | 2008-12-12 | 2010-06-17 | Oncotherapy Science, Inc. | Nectin-4 for target genes of cancer therapy and diagnosis |
| TWI469791B (zh) | 2009-02-18 | 2015-01-21 | Oncotherapy Science Inc | Ｆｏｘｍ１胜肽以及含此胜肽之疫苗 |
| ES2703714T3 (es) | 2009-03-12 | 2019-03-12 | Cancer Prevention & Cure Ltd | Métodos de identificación, evaluación, prevención y terapia de enfermedades pulmonares y kits de los mismos, incluida la identificación, evaluación, prevención y terapia de enfermedades en base al género |
| TW201102081A (en) | 2009-05-11 | 2011-01-16 | Oncotherapy Science Inc | TTK peptides and vaccines including the same |
| WO2011027807A1 (ja) * | 2009-09-03 | 2011-03-10 | 東レ株式会社 | 免疫誘導剤 |
| JP5728718B2 (ja) | 2009-12-28 | 2015-06-03 | オンコセラピー・サイエンス株式会社 | 抗ｃｄｈ３抗体およびその使用 |
| TWI485245B (zh) | 2010-01-25 | 2015-05-21 | Oncotherapy Science Inc | 經修飾之ｍｅｌｋ胜肽及含此胜肽之疫苗 |
| KR101872284B1 (ko) | 2010-03-11 | 2018-06-28 | 온코세라피 사이언스 가부시키가이샤 | Ｈｊｕｒｐ 펩티드 및 이를 포함한 백신 |
| WO2011129427A1 (ja) * | 2010-04-16 | 2011-10-20 | 第一三共株式会社 | 癌の診断剤および治療剤 |
| SG187633A1 (en) | 2010-07-30 | 2013-03-28 | Oncotherapy Science Inc | Quinoline derivatives and melk inhibitors containing the same |
| WO2012028899A1 (en) * | 2010-09-02 | 2012-03-08 | Inserm ( Institut National De La Sante Et De La Recherche Medicale) | Methods for the treatment and the diagnosis of cancer |
| EP2702411A4 (en) * | 2011-04-29 | 2015-07-22 | Cancer Prevention & Cure Ltd | METHOD FOR IDENTIFICATION AND DIAGNOSIS OF LUNG DISEASES USING CLASSIFICATION SYSTEMS AND KITS THEREFOR |
| WO2012153492A1 (en) * | 2011-05-06 | 2012-11-15 | Oncotherapy Science, Inc. | Nptx2 as tumor marker and therapeutic target for cancer |
| WO2012157239A1 (en) * | 2011-05-16 | 2012-11-22 | Oncotherapy Science, Inc. | Chodl as tumor marker and therapeutic target for cancer |
| JP5564730B2 (ja) | 2011-08-12 | 2014-08-06 | オンコセラピー・サイエンス株式会社 | Ｍｐｈｏｓｐｈ１ペプチドおよびそれを含むワクチン |
| CN103987861A (zh) | 2011-10-14 | 2014-08-13 | 加州大学评议会 | 皮肤鳞状细胞癌和假性上皮瘤样增生的基于多重pcr的测试及其区分方法 |
| DK2753329T3 (en) | 2012-01-19 | 2017-10-23 | Onco Therapy Science Inc | 1,5-NAPHTHYRIDINE INGREDIENTS AS MILK INHIBITORS |
| KR101308924B1 (ko) * | 2012-02-21 | 2013-09-23 | 차의과학대학교 산학협력단 | 신규한 ｍｉＲＮＡ ｈｃ－ｓｍＲ－Ｓ２－５ 및 이의 용도 |
| WO2013133405A1 (ja) | 2012-03-09 | 2013-09-12 | オンコセラピー・サイエンス株式会社 | ペプチドを含む医薬組成物 |
| JO3623B1 (ar) | 2012-05-18 | 2020-08-27 | Amgen Inc | البروتينات المرتبطة بمولد المستضاد st2 |
| JP6255593B2 (ja) | 2012-07-10 | 2018-01-10 | オンコセラピー・サイエンス株式会社 | Ｔｈ１細胞のＣＤＣＡ１エピトープペプチドおよびこれを含有するワクチン |
| US9644010B2 (en) | 2012-07-10 | 2017-05-09 | Oncotherapy Science, Inc. | LY6K epitope peptides for TH1 cells and vaccines containing the same |
| GB201213229D0 (en) * | 2012-07-25 | 2012-09-05 | Isis Innovation | Assay |
| TWI658049B (zh) | 2013-03-12 | 2019-05-01 | 腫瘤療法 科學股份有限公司 | Ｋｎｔｃ２胜肽及含此胜肽之疫苗 |
| KR101447901B1 (ko) * | 2013-04-16 | 2014-10-16 | 한양대학교 산학협력단 | 지방세포 표적 비바이러스성 유전자 전달체 |
| TWI627182B (zh) | 2013-05-24 | 2018-06-21 | 腫瘤療法 科學股份有限公司 | 對於ｔｈ１細胞之ｉｍｐ－３抗原決定位胜肽及含此之疫苗 |
| JP2017516501A (ja) | 2014-05-30 | 2017-06-22 | ジーンセントリック ダイアグノスティクス， インコーポレイテッド | 肺がんのタイピング法 |
| SG10201900835XA (en) | 2014-08-04 | 2019-03-28 | Oncotherapy Science Inc | Urlc10-derived peptide and vaccine containing same |
| EP3981416B1 (en) | 2014-08-04 | 2024-03-20 | OncoTherapy Science, Inc. | Koc1-derived peptide and vaccine including same |
| WO2016121715A1 (ja) * | 2015-01-26 | 2016-08-04 | 国立大学法人名古屋大学 | 肺がん患者の予後を評価するための情報を提供する方法、肺がん患者の予後予測方法、内部標準、抗体、肺がん患者の予後予測装置、予後予測装置のプログラム及び記録媒体 |
| US20190203296A1 (en) * | 2015-04-14 | 2019-07-04 | Genecentric Therapeutics, Inc. | Methods for typing of lung cancer |
| US20190185851A1 (en) * | 2015-09-09 | 2019-06-20 | Theoria Science Inc. | Exosome secretion inhibitor |
| BR112018005581A2 (pt) | 2015-10-08 | 2018-10-16 | Oncotherapy Science, Inc. | peptídeo derivado de foxm1 e vacina incluindo o mesmo |
| US10793599B2 (en) | 2015-10-08 | 2020-10-06 | Oncotherapy Science, Inc. | MPHOSPH1-derived peptide, and vaccine including same |
| WO2021016946A1 (zh) | 2019-07-31 | 2021-02-04 | 京东方科技集团股份有限公司 | 显示基板及其制备方法、显示面板、显示装置 |
| JP7241352B2 (ja) | 2016-05-17 | 2023-03-17 | ジーンセントリック セラピューティクス， インコーポレイテッド | 肺扁平上皮癌のサブタイピングのための方法 |
| CA3024747A1 (en) | 2016-05-17 | 2017-11-23 | Genecentric Therapeutics, Inc. | Methods for subtyping of lung adenocarcinoma |
| SG10202100683RA (en) | 2016-08-31 | 2021-03-30 | Oncotherapy Science Inc | Monoclonal antibody against melk and utilization thereof |
| TWI762516B (zh) | 2016-10-06 | 2022-05-01 | 日商腫瘤療法 科學股份有限公司 | 針對ｆｚｄ１０之單株抗體及其用途 |
| NL2020004B1 (en) | 2016-12-09 | 2018-07-02 | Ary Flohil Jacob | Treatment of diffuse intrinsic pontine glioma |
| MY192920A (en) * | 2017-03-15 | 2022-09-15 | Cancer Res Malaysia | Immunogenic peptide composition |
| CN110709936A (zh) | 2017-04-04 | 2020-01-17 | 肺癌蛋白质组学有限责任公司 | 用于早期肺癌预后的基于血浆的蛋白质概况分析 |
| TW202023581A (zh) | 2018-08-02 | 2020-07-01 | 日商腫瘤療法 科學股份有限公司 | 來自cdca1的胜肽及含有此的疫苗 |
| KR102540416B1 (ko) * | 2021-04-09 | 2023-06-12 | 주식회사 애티스랩 | 암 진단용 조성물, 키트, 및 이를 이용한 암 진단 방법 |
| KR102732170B1 (ko) | 2021-05-20 | 2024-11-19 | 한국식품연구원 | 구강미생물 정보를 이용한 폐암의 조기진단 및 위험성 예측 방법 또는 이를 위한 조성물 |
| CN113925877B (zh) * | 2021-10-28 | 2022-06-07 | 青岛西凯生物技术有限公司 | 基因增强型免疫细胞在肺癌中的应用 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0239102A3 (en) | 1986-03-28 | 1989-07-12 | Tsuji, Kimiyoshi | Process for the formation of human-human hybridoma |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| ES2108048T3 (es) | 1990-08-29 | 1997-12-16 | Genpharm Int | Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos. |
| GB9114005D0 (en) | 1991-06-28 | 1991-08-14 | Automotive Prod Plc | A clutch control system |
| WO1993002227A1 (en) | 1991-07-15 | 1993-02-04 | Eco-Tec Limited | Process and apparatus for treating fluoride containing acid solutions |
| EP0746609A4 (en) | 1991-12-17 | 1997-12-17 | Genpharm Int | NON-HUMAN TRANSGENIC ANIMALS CAPABLE OF PRODUCING HETEROLOGOUS ANTIBODIES |
| JPH07509137A (ja) | 1992-07-24 | 1995-10-12 | セル ジェネシス，インク． | 異種抗体の生産 |
| JPH08509612A (ja) | 1993-04-26 | 1996-10-15 | ジェンファーム インターナショナル インコーポレイテッド | 異種抗体を産生することができるトランスジェニック非ヒト動物 |
| US5403494A (en) | 1993-07-15 | 1995-04-04 | The Lawrence Paper Company | Method of recovery of single color printing ink wastes |
| EP0822830B1 (en) | 1995-04-27 | 2008-04-02 | Amgen Fremont Inc. | Human anti-IL-8 antibodies, derived from immunized xenomice |
| CA2219486A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| JP2002519000A (ja) * | 1998-01-28 | 2002-07-02 | カイロン コーポレイション | ヒト遺伝子および遺伝子発現産物ｉｉ |
| AU4187499A (en) * | 1998-05-14 | 1999-11-29 | Chiron Corporation | Human genes and gene expression products v |
| US20020103360A1 (en) | 1998-09-01 | 2002-08-01 | Yang Pan | Novel protein related to melanoma-inhibiting protein and uses thereof |
| EP1130094A3 (en) * | 1999-07-08 | 2001-11-21 | Helix Research Institute | Primers for synthesizing full length cDNA clones and their use |
| ATE420175T1 (de) * | 1999-08-12 | 2009-01-15 | Agensys Inc | C-typ lektin transmembranantigen, das in menschlichen prostatkrebs exprimiert wird, und deren verwendungen |
| EP1572987A4 (en) * | 2000-02-03 | 2005-11-30 | Nuvelo Inc | NUCLEIC ACIDS AND POLYPEPTIDES |
| JP2003528630A (ja) * | 2000-03-28 | 2003-09-30 | カイロン コーポレイション | ヒト遺伝子および発現産物 |
| US20020119156A1 (en) * | 2000-03-29 | 2002-08-29 | Sei-Yu Chen | Compositions and methods of diagnosing, monitoring, staging, imaging and treating lung cancer |
| US6436703B1 (en) * | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
| JP2004509612A (ja) * | 2000-06-05 | 2004-04-02 | アバロン ファーマシューティカルズ | ガン遺伝子決定および特徴的な遺伝子群を用いた治療用スクリーニング |
| US6974667B2 (en) * | 2000-06-14 | 2005-12-13 | Gene Logic, Inc. | Gene expression profiles in liver cancer |
| EP1343886A2 (en) * | 2000-07-11 | 2003-09-17 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
| WO2002059271A2 (en) * | 2001-01-25 | 2002-08-01 | Gene Logic, Inc. | Gene expression profiles in breast tissue |
| ATE553112T1 (de) * | 2001-02-21 | 2012-04-15 | Novartis Vaccines & Diagnostic | Ttk in der diagnose und als therapeutisches target bei krebs |
| AU2002258518A1 (en) * | 2001-03-14 | 2002-09-24 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer |
| JP2005527180A (ja) * | 2001-04-18 | 2005-09-15 | プロテイン デザイン ラブス， インコーポレイテッド | 肺がんの診断方法、肺がんの修飾因子の組成及びスクリーニングの方法 |
| JP4658936B2 (ja) * | 2004-03-24 | 2011-03-23 | オンコセラピー・サイエンス株式会社 | 肺癌を治療するための組成物および方法 |
| EP1853703B1 (en) * | 2005-02-25 | 2011-04-13 | Oncotherapy Science, Inc. | Peptide vaccines for lung cancers expressing ttk polypeptides |
| EP2061900A2 (en) * | 2006-08-25 | 2009-05-27 | Oncotherapy Science, Inc. | Prognostic markers and therapeutic targets for lung cancer |
| TW200920406A (en) * | 2007-08-24 | 2009-05-16 | Oncotherapy Science Inc | EBI3, DLX5, NPTX1 and CDKN3 for target genes of lung cancer therapy and diagnosis |
-
2003
- 2003-09-15 TW TW092125317A patent/TW200413725A/zh unknown
- 2003-09-22 EP EP10010332A patent/EP2270224A3/en not_active Withdrawn
- 2003-09-22 WO PCT/JP2003/012072 patent/WO2004031413A2/en not_active Ceased
- 2003-09-22 EP EP10010329A patent/EP2270221A3/en not_active Withdrawn
- 2003-09-22 EP EP10010308A patent/EP2264187A1/en not_active Withdrawn
- 2003-09-22 AT AT06022167T patent/ATE541053T1/de active
- 2003-09-22 EP EP10010316A patent/EP2270502A3/en not_active Withdrawn
- 2003-09-22 EP EP03753941A patent/EP1551998A2/en not_active Withdrawn
- 2003-09-22 EP EP06022167A patent/EP1743947B1/en not_active Expired - Lifetime
- 2003-09-22 EP EP10010314A patent/EP2270500A1/en not_active Withdrawn
- 2003-09-22 EP EP10010322A patent/EP2270214A3/en not_active Withdrawn
- 2003-09-22 EP EP10010312A patent/EP2270498A3/en not_active Withdrawn
- 2003-09-22 EP EP10010328A patent/EP2270220A3/en not_active Withdrawn
- 2003-09-22 EP EP10010311A patent/EP2278028A1/en not_active Withdrawn
- 2003-09-22 EP EP10010310A patent/EP2264457A1/en not_active Withdrawn
- 2003-09-22 CA CA002500151A patent/CA2500151A1/en not_active Abandoned
- 2003-09-22 EP EP10010333A patent/EP2270225A3/en not_active Withdrawn
- 2003-09-22 JP JP2004541231A patent/JP4425141B2/ja not_active Expired - Fee Related
- 2003-09-22 EP EP10010306A patent/EP2264185A1/en not_active Withdrawn
- 2003-09-22 EP EP10010307A patent/EP2264186A1/en not_active Withdrawn
- 2003-09-22 EP EP10010325A patent/EP2270217A3/en not_active Withdrawn
- 2003-09-22 EP EP10010309A patent/EP2264190A1/en not_active Withdrawn
- 2003-09-22 EP EP10010330A patent/EP2270222A2/en not_active Withdrawn
- 2003-09-22 EP EP10010323A patent/EP2270215A3/en not_active Withdrawn
- 2003-09-22 KR KR1020057005561A patent/KR101075158B1/ko not_active Expired - Fee Related
- 2003-09-22 EP EP10010324A patent/EP2270216A3/en not_active Withdrawn
- 2003-09-22 EP EP10010317A patent/EP2270503A3/en not_active Withdrawn
- 2003-09-22 EP EP10010315A patent/EP2270501A3/en not_active Withdrawn
- 2003-09-22 EP EP10010321A patent/EP2270213A3/en not_active Withdrawn
- 2003-09-22 EP EP10010331A patent/EP2270223A2/en not_active Withdrawn
- 2003-09-22 EP EP10010327A patent/EP2270219A3/en not_active Withdrawn
- 2003-09-22 EP EP10010319A patent/EP2270211A3/en not_active Withdrawn
- 2003-09-22 EP EP10010326A patent/EP2270218A2/en not_active Withdrawn
- 2003-09-22 EP EP10010318A patent/EP2270210A3/en not_active Withdrawn
- 2003-09-22 KR KR1020117003536A patent/KR20110020953A/ko not_active Abandoned
- 2003-09-22 AU AU2003272088A patent/AU2003272088A1/en not_active Abandoned
- 2003-09-22 EP EP10010313A patent/EP2270499A1/en not_active Withdrawn
- 2003-09-22 EP EP10010320A patent/EP2270212A3/en not_active Withdrawn
-
2009
- 2009-06-09 JP JP2009138122A patent/JP4921522B2/ja not_active Expired - Fee Related
- 2009-10-05 JP JP2009231138A patent/JP2010042016A/ja active Pending
-
2012
- 2012-01-11 JP JP2012003039A patent/JP2012125247A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006500949A5 (enExample) | ||
| JP2007506426A5 (enExample) | ||
| JP2006500948A5 (enExample) | ||
| JP2009502116A5 (enExample) | ||
| JP2009502115A5 (enExample) | ||
| KR20130115250A (ko) | 암에 대한 분자적 진단 테스트 | |
| KR20160052729A (ko) | 폐암에 대한 분자적 진단 검사 | |
| EP2691538A1 (en) | Markers associated with cyclin-dependent kinase inhibitors | |
| CN111876478B (zh) | 肺结节诊断标志物及应用 | |
| JP2010535014A5 (enExample) | ||
| KR20160057416A (ko) | 식도암에 대한 분자적 진단 검사 | |
| SG190570A1 (en) | Antiviral therapy | |
| US12325880B2 (en) | Identification of PDE3 modulator responsive cancers | |
| WO2009034055A1 (en) | Method for predicting the response of a subject suffering from a viral infection of the liver to an antiviral therapy | |
| JP2005537007A5 (enExample) | ||
| AU2019270404B2 (en) | Blood biomarkers of stroke | |
| KR20190089552A (ko) | 비근침윤성 방광암 진단용 바이오마커 및 이의 용도 | |
| WO2018223867A1 (zh) | 一种前列腺癌的标志物spop及其在指导肿瘤治疗中的应用 | |
| JP2008512984A5 (enExample) | ||
| JP2005537027A5 (enExample) | ||
| JP2003524017A5 (enExample) | ||
| WO2010054379A2 (en) | Gene signature for predicting prognosis of patients with solid tumors | |
| US20110236396A1 (en) | Methods and compositions for diagnosing and treating a colorectal adenocarcinoma | |
| JP2006503575A5 (enExample) | ||
| EP4073510A1 (en) | Materials and methods for inflammatory molecular markers |