ATE541053T1 - Verfahren und zusammensetzungen zur behandlung von nichtkleinzelligem lungenkrebs - Google Patents
Verfahren und zusammensetzungen zur behandlung von nichtkleinzelligem lungenkrebsInfo
- Publication number
- ATE541053T1 ATE541053T1 AT06022167T AT06022167T ATE541053T1 AT E541053 T1 ATE541053 T1 AT E541053T1 AT 06022167 T AT06022167 T AT 06022167T AT 06022167 T AT06022167 T AT 06022167T AT E541053 T1 ATE541053 T1 AT E541053T1
- Authority
- AT
- Austria
- Prior art keywords
- lung cancer
- small cell
- cell lung
- methods
- compositions
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57423—Specifically defined cancers of lung
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41467302P | 2002-09-30 | 2002-09-30 | |
US45137403P | 2003-02-28 | 2003-02-28 | |
US46610003P | 2003-04-28 | 2003-04-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE541053T1 true ATE541053T1 (de) | 2012-01-15 |
Family
ID=32074369
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06022167T ATE541053T1 (de) | 2002-09-30 | 2003-09-22 | Verfahren und zusammensetzungen zur behandlung von nichtkleinzelligem lungenkrebs |
Country Status (8)
Country | Link |
---|---|
EP (30) | EP2270499A1 (de) |
JP (4) | JP4425141B2 (de) |
KR (2) | KR101075158B1 (de) |
AT (1) | ATE541053T1 (de) |
AU (1) | AU2003272088A1 (de) |
CA (1) | CA2500151A1 (de) |
TW (1) | TW200413725A (de) |
WO (1) | WO2004031413A2 (de) |
Families Citing this family (94)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5300469A (en) * | 1992-12-08 | 1994-04-05 | Engelhard Corporation | Composition for passivating vanadium in catalytic cracking and preparation thereof |
US8048629B2 (en) * | 1996-03-15 | 2011-11-01 | The Penn State Research Foundation | Detection of extracellular tumor-associated nucleic acid in blood plasma or serum |
AU2003262717A1 (en) * | 2002-08-15 | 2004-03-03 | Genzyme Corporation | Brain endothelial cell expression patterns |
WO2005090991A1 (en) * | 2004-03-24 | 2005-09-29 | Oncotherapy Science, Inc. | Adam8 as tumor marker and therapeutic target for non-small cell lung cancer |
JP4742023B2 (ja) * | 2003-01-03 | 2011-08-10 | ゲンシア コーポレーション | 脱毛に関与する遺伝子の、siRNA転写後遺伝子サイレンシング |
US20050112622A1 (en) * | 2003-08-11 | 2005-05-26 | Ring Brian Z. | Reagents and methods for use in cancer diagnosis, classification and therapy |
US20050186577A1 (en) | 2004-02-20 | 2005-08-25 | Yixin Wang | Breast cancer prognostics |
JP4658936B2 (ja) * | 2004-03-24 | 2011-03-23 | オンコセラピー・サイエンス株式会社 | 肺癌を治療するための組成物および方法 |
ATE483979T1 (de) * | 2004-08-10 | 2010-10-15 | Oncotherapy Science Inc | Gen anln in verbindung mit nicht-kleinzelligem lungenkrebs und seine wechselwirkungen mit rhoa |
JP5028601B2 (ja) * | 2004-08-10 | 2012-09-19 | オンコセラピー・サイエンス株式会社 | 乳癌に関連する遺伝子およびポリペプチド |
CN101061239B (zh) | 2004-09-24 | 2011-08-17 | 肿瘤疗法科学股份有限公司 | 通过URLC8的tRNA-二氢尿苷合酶活性诊断非小细胞肺癌的方法 |
ATE451619T1 (de) * | 2004-10-19 | 2009-12-15 | Onco Therapy Science Inc | Pkp3-onkogen als prognostischer indikator für lungenadenokarzinom |
WO2006056080A1 (en) * | 2004-11-29 | 2006-06-01 | Diagnocure Inc. | Gpx2 a specific and sensitive target for lung cancer diagnosis, prognosis and/or theranosis |
DE602005023216D1 (de) * | 2004-12-15 | 2010-10-07 | Beth Israel Hospital | Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationen |
WO2006085684A2 (en) * | 2005-02-10 | 2006-08-17 | Oncotherapy Science, Inc. | Method of diagnosing bladder cancer |
DK2325305T3 (en) | 2005-02-25 | 2014-03-03 | Oncotherapy Science Inc | Peptide vaccines for cancers that express TTK-, URLC10- or KOC1 polypeptide |
CA2599875A1 (en) * | 2005-03-03 | 2006-09-08 | Takeda Pharmaceutical Company Limited | Preventive/therapeutic agent for cancer |
WO2006105642A1 (en) * | 2005-04-05 | 2006-10-12 | British Columbia Cancer Agency | Biomarkers for the detection of lung cancer and uses thereof |
EP1888639A1 (de) * | 2005-05-12 | 2008-02-20 | Oncotherapy Science, Inc. | Verfahren zur schädigung von zellen unter verwendung der effektorfunktion eines anti-dsc2-antikörpers |
CN101273144B (zh) | 2005-07-27 | 2011-12-28 | 肿瘤疗法科学股份有限公司 | 诊断食道癌的方法 |
DE102005052384B4 (de) * | 2005-10-31 | 2009-09-24 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur Erkennung, Markierung und Behandlung von epithelialen Lungentumorzellen sowie Mittel zur Durchführung des Verfahrens |
KR100759288B1 (ko) * | 2005-11-14 | 2007-09-17 | 가톨릭대학교 산학협력단 | 비교유전자보합법을 이용한 폐암 및 폐암의 하부유형 진단방법 |
JP5321780B2 (ja) | 2006-02-10 | 2013-10-23 | オンコセラピー・サイエンス株式会社 | 肺癌の治療方法 |
WO2007123247A1 (en) * | 2006-04-20 | 2007-11-01 | Oncotherapy Science, Inc. | NMU-GHSR1b/NTSR1 ONCOGENIC SIGNALING PATHWAY AS A THERAPEUTIC TARGET FOR LUNG CANCER |
WO2008014951A1 (en) * | 2006-08-01 | 2008-02-07 | Roche Diagnostics Gmbh | Use of nnmt as a marker for lung cancer |
US7851144B2 (en) | 2006-08-18 | 2010-12-14 | The University Of Washington | Compositions and methods for detecting cancer |
WO2008020653A1 (en) * | 2006-08-18 | 2008-02-21 | Oncotherapy Science, Inc. | Use of holliday junction-recognizing protein related to cancer |
US20110070245A1 (en) * | 2006-08-18 | 2011-03-24 | Oncotherapy Science Inc. | Imp-1 oncogene as a therapeutic target and prognostic indicator for lung cancer |
EP2423333A1 (de) | 2006-08-25 | 2012-02-29 | Oncotherapy Science, Inc. | Prognosemarker und therapeutische Targets für Lungenkrebs |
WO2008026946A2 (en) * | 2006-08-30 | 2008-03-06 | Genesis Research And Development Corporation Limited | Compositions and methods for the treatment and prevention of neoplastic disorders |
EP2695895A1 (de) | 2006-10-17 | 2014-02-12 | Oncotherapy Science, Inc. | Peptidvakzinen für MPHOSPH1- oder DEPDC1-Polypeptide exprimierenden Krebs |
EP2102360A2 (de) | 2006-12-13 | 2009-09-23 | Oncotherapy Science, Inc. | Ttk als tumormarker und therapeutisches ziel für lungenkrebs |
KR100846354B1 (ko) * | 2007-03-21 | 2008-07-15 | (주) 프로탄바이오 | 혈청 당단백질부터 분리한 폐암 진단용 마커 |
WO2008120812A1 (en) * | 2007-03-30 | 2008-10-09 | Oncotherapy Science, Inc. | Screening and therapeutic method for nsclc targeting the cdca8-aurkb complex |
WO2008151110A2 (en) * | 2007-06-01 | 2008-12-11 | The University Of North Carolina At Chapel Hill | Molecular diagnosis and typing of lung cancer variants |
EP2185732A1 (de) * | 2007-07-30 | 2010-05-19 | Oncotherapy Science, Inc. | Mit krebs assoziiertes gen ly6k |
SG183698A1 (en) * | 2007-08-20 | 2012-09-27 | Oncotherapy Science Inc | Cdca1 peptide and pharmaceutical agent comprising the same |
KR101543624B1 (ko) | 2007-08-20 | 2015-08-11 | 온코세라피 사이언스 가부시키가이샤 | Foxm1 펩티드 및 이를 포함하는 약학적 조성물 |
WO2009025116A1 (ja) | 2007-08-20 | 2009-02-26 | Oncotherapy Science, Inc. | Cdh3ペプチド及びこれを含む薬剤 |
US8541183B2 (en) | 2007-09-11 | 2013-09-24 | Cancer Prevention And Cure, Ltd. | Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof |
CA2705509A1 (en) | 2007-11-14 | 2009-05-22 | Forerunner Pharma Research Co., Ltd. | Diagnosis and treatment of cancer using anti-gpr49 antibody |
TWI526219B (zh) | 2008-06-19 | 2016-03-21 | 腫瘤療法 科學股份有限公司 | Cdca1抗原決定位胜肽及含此胜肽的疫苗 |
KR20110025215A (ko) | 2008-06-30 | 2011-03-09 | 온코세라피 사이언스 가부시키가이샤 | 방사성 동위원소 표지로 표지된 항―cdh3 항체 및 이의 용도 |
TWI466680B (zh) | 2008-08-01 | 2015-01-01 | Oncotherapy Science Inc | Melk抗原決定位胜肽及含此胜肽的疫苗 |
TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
TWI543767B (zh) | 2008-08-19 | 2016-08-01 | 腫瘤療法 科學股份有限公司 | Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗 |
JP2012501166A (ja) * | 2008-08-27 | 2012-01-19 | オンコセラピー・サイエンス株式会社 | 乳癌関連遺伝子rqcd1 |
JP2012501167A (ja) * | 2008-08-27 | 2012-01-19 | オンコセラピー・サイエンス株式会社 | 膵臓癌関連遺伝子ttll4 |
US20110160288A1 (en) * | 2008-08-28 | 2011-06-30 | Oncotherapy Science, Inc. | Oip5 as a target gene for cancer therapy and diagnosis |
KR101064561B1 (ko) * | 2008-09-24 | 2011-09-14 | 고려대학교 산학협력단 | 폐선암 수술 후 초기 재발 예측용 바이오마커 |
JP2012511305A (ja) * | 2008-12-12 | 2012-05-24 | オンコセラピー・サイエンス株式会社 | 癌の治療および診断の標的遺伝子としてのネクチン−4 |
TWI469791B (zh) | 2009-02-18 | 2015-01-21 | Oncotherapy Science Inc | Foxm1胜肽以及含此胜肽之疫苗 |
EP2857522A3 (de) | 2009-03-12 | 2015-10-14 | Cancer Prevention And Cure, Ltd. | Verfahren zur Identifizierung, Beurteilung, Prävention und Behandlung von Lungenerkrankungen sowie Kits dafür mit geschlechtsspezifischer Krankheitsidentifizierung, Beurteilung, Prävention und Behandlung |
TW201102081A (en) | 2009-05-11 | 2011-01-16 | Oncotherapy Science Inc | TTK peptides and vaccines including the same |
US9289465B2 (en) * | 2009-09-03 | 2016-03-22 | Toray Industries, Inc. | Immunity-inducing agent |
EP2519542B1 (de) | 2009-12-28 | 2018-10-10 | OncoTherapy Science, Inc. | Anti-cdh3-antikörper und ihre verwendung |
TWI485245B (zh) | 2010-01-25 | 2015-05-21 | Oncotherapy Science Inc | 經修飾之melk胜肽及含此胜肽之疫苗 |
EP2545171B1 (de) | 2010-03-11 | 2017-12-20 | OncoTherapy Science, Inc. | Hjurp-peptide und diese enthaltende impfstoffe |
WO2011129427A1 (ja) * | 2010-04-16 | 2011-10-20 | 第一三共株式会社 | 癌の診断剤および治療剤 |
CA2806332C (en) | 2010-07-30 | 2017-11-14 | Oncotherapy Science, Inc. | Quinoline derivatives and melk inhibitors containing the same |
US8933050B2 (en) | 2010-09-02 | 2015-01-13 | Institute National De La Sante Et De La Recherche Medicale (Inserm) | Methods for the treatment and the diagnosis of cancer |
CA3120217A1 (en) * | 2011-04-29 | 2012-11-01 | Cancer Prevention And Cure, Ltd. | Methods of identification and diagnosis of lung diseases using classification systems and kits thereof |
WO2012153492A1 (en) * | 2011-05-06 | 2012-11-15 | Oncotherapy Science, Inc. | Nptx2 as tumor marker and therapeutic target for cancer |
WO2012157239A1 (en) * | 2011-05-16 | 2012-11-22 | Oncotherapy Science, Inc. | Chodl as tumor marker and therapeutic target for cancer |
CA2842887C (en) | 2011-08-12 | 2021-01-19 | Oncotherapy Science, Inc. | Mphosph1 peptides and vaccines including the same |
CN103987861A (zh) | 2011-10-14 | 2014-08-13 | 加州大学评议会 | 皮肤鳞状细胞癌和假性上皮瘤样增生的基于多重pcr的测试及其区分方法 |
MX366983B (es) | 2012-01-19 | 2019-08-01 | Oncotherapy Science Inc | Derivados de 1,5-naftiridina e inhibidores de cinasa de cremallallera de leucina embrionica materna que los contienen. |
KR101308924B1 (ko) * | 2012-02-21 | 2013-09-23 | 차의과학대학교 산학협력단 | 신규한 miRNA hc-smR-S2-5 및 이의 용도 |
WO2013133405A1 (ja) | 2012-03-09 | 2013-09-12 | オンコセラピー・サイエンス株式会社 | ペプチドを含む医薬組成物 |
JO3623B1 (ar) | 2012-05-18 | 2020-08-27 | Amgen Inc | البروتينات المرتبطة بمولد المستضاد st2 |
WO2014010229A1 (en) | 2012-07-10 | 2014-01-16 | Oncotherapy Science, Inc. | Cdca1 epitope peptides for th1 cells and vaccines containing the same |
WO2014010232A1 (en) | 2012-07-10 | 2014-01-16 | Oncotherapy Science, Inc. | Ly6k epitope peptides for th1 cells and vaccines containing the same |
GB201213229D0 (en) * | 2012-07-25 | 2012-09-05 | Isis Innovation | Assay |
TWI658049B (zh) | 2013-03-12 | 2019-05-01 | 腫瘤療法 科學股份有限公司 | Kntc2胜肽及含此胜肽之疫苗 |
KR101447901B1 (ko) * | 2013-04-16 | 2014-10-16 | 한양대학교 산학협력단 | 지방세포 표적 비바이러스성 유전자 전달체 |
TWI627182B (zh) | 2013-05-24 | 2018-06-21 | 腫瘤療法 科學股份有限公司 | 對於th1細胞之imp-3抗原決定位胜肽及含此之疫苗 |
WO2015184461A1 (en) | 2014-05-30 | 2015-12-03 | Faruki Hawazin | Methods for typing of lung cancer |
WO2016021506A1 (ja) | 2014-08-04 | 2016-02-11 | オンコセラピー・サイエンス株式会社 | Koc1由来ペプチドおよびそれを含むワクチン |
SG10201900835XA (en) | 2014-08-04 | 2019-03-28 | Oncotherapy Science Inc | Urlc10-derived peptide and vaccine containing same |
WO2016121715A1 (ja) * | 2015-01-26 | 2016-08-04 | 国立大学法人名古屋大学 | 肺がん患者の予後を評価するための情報を提供する方法、肺がん患者の予後予測方法、内部標準、抗体、肺がん患者の予後予測装置、予後予測装置のプログラム及び記録媒体 |
WO2016168446A1 (en) * | 2015-04-14 | 2016-10-20 | Genecentric Diagnostics, Inc. | Methods for typing of lung cancer |
JP6895175B2 (ja) * | 2015-09-09 | 2021-06-30 | テオリアサイエンス株式会社 | エクソソーム分泌阻害剤 |
BR112018005581A2 (pt) | 2015-10-08 | 2018-10-16 | Oncotherapy Science, Inc. | peptídeo derivado de foxm1 e vacina incluindo o mesmo |
SG11201802286PA (en) | 2015-10-08 | 2018-04-27 | Oncotherapy Science Inc | Mphosph1-derived peptide, and vaccine including same |
US11041214B2 (en) | 2016-05-17 | 2021-06-22 | Genecentric Therapeutics, Inc. | Methods for subtyping of lung squamous cell carcinoma |
EP3458612B1 (de) | 2016-05-17 | 2023-11-15 | Genecentric Therapeutics, Inc. | Verfahren zur subtypisierung von lungenadenokarzinomen |
BR112019003408A2 (pt) | 2016-08-31 | 2019-06-25 | Oncotherapy Science Inc | anticorpo monoclonal contra a melk e utilização da mesma |
TWI762516B (zh) | 2016-10-06 | 2022-05-01 | 日商腫瘤療法 科學股份有限公司 | 針對fzd10之單株抗體及其用途 |
NL2020004B1 (en) | 2016-12-09 | 2018-07-02 | Ary Flohil Jacob | Treatment of diffuse intrinsic pontine glioma |
MY192920A (en) * | 2017-03-15 | 2022-09-15 | Cancer Res Malaysia | Immunogenic peptide composition |
CN110709936A (zh) | 2017-04-04 | 2020-01-17 | 肺癌蛋白质组学有限责任公司 | 用于早期肺癌预后的基于血浆的蛋白质概况分析 |
EP4006983A4 (de) | 2019-07-31 | 2022-11-16 | BOE Technology Group Co., Ltd. | Anzeigesubstrat und herstellungsverfahren dafür, anzeigetafel und anzeigevorrichtung |
KR20220157009A (ko) | 2021-05-20 | 2022-11-29 | 한국식품연구원 | 구강미생물 정보를 이용한 폐암의 조기진단 및 위험성 예측 방법 또는 이를 위한 조성물 |
CN113925877B (zh) * | 2021-10-28 | 2022-06-07 | 青岛西凯生物技术有限公司 | 基因增强型免疫细胞在肺癌中的应用 |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0239102A3 (de) | 1986-03-28 | 1989-07-12 | Tsuji, Kimiyoshi | Verfahren zur Herstellung eines Human-Human-Hybridoms |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
CA2089661C (en) | 1990-08-29 | 2007-04-03 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
GB9114005D0 (en) | 1991-06-28 | 1991-08-14 | Automotive Prod Plc | A clutch control system |
WO1993002227A1 (en) | 1991-07-15 | 1993-02-04 | Eco-Tec Limited | Process and apparatus for treating fluoride containing acid solutions |
EP0746609A4 (de) | 1991-12-17 | 1997-12-17 | Genpharm Int | Heterologe antikörper produzierende transgene nicht-humane tiere |
SG48760A1 (en) | 1992-07-24 | 2003-03-18 | Abgenix Inc | Generation of xenogenetic antibodies |
AU6819494A (en) | 1993-04-26 | 1994-11-21 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5403494A (en) | 1993-07-15 | 1995-04-04 | The Lawrence Paper Company | Method of recovery of single color printing ink wastes |
ATE390933T1 (de) | 1995-04-27 | 2008-04-15 | Amgen Fremont Inc | Aus immunisierten xenomäusen stammende menschliche antikörper gegen il-8 |
CA2219486A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
EP1053319A2 (de) * | 1998-01-28 | 2000-11-22 | Chiron Corporation | Menschliche gene und expressionsprodukte ii |
WO1999058675A2 (en) * | 1998-05-14 | 1999-11-18 | Chiron Corporation | Human genes and gene expression products v |
US20020103360A1 (en) | 1998-09-01 | 2002-08-01 | Yang Pan | Novel protein related to melanoma-inhibiting protein and uses thereof |
EP1130094A3 (de) * | 1999-07-08 | 2001-11-21 | Helix Research Institute | Primer zur Synthese von vollständigen cDNA Klonen und ihre Verwendung |
DK1992695T3 (da) * | 1999-08-12 | 2011-02-14 | Agensys Inc | Lectin-transmembran-antigen af type C udtrykt i human prostatacancer og avendelser deraf |
EP1572987A4 (de) * | 2000-02-03 | 2005-11-30 | Nuvelo Inc | Neuartige nukleinsäure und polypeptide |
AU2001287269A1 (en) * | 2000-03-28 | 2001-10-08 | Chiron Corporation | Human genes and expression products |
AU2001251084A1 (en) * | 2000-03-29 | 2001-10-08 | Diadexus, Inc. | Polynucleotides and polypeptides as well as methods for diagnosing and treating lung cancer |
US6436703B1 (en) * | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
EP1358349A2 (de) * | 2000-06-05 | 2003-11-05 | Avalon Pharmaceuticals | Bestimmung von krebsgenen und therapeutisches screeningverfahren das signaturen von gensätzen verwendet |
US6974667B2 (en) * | 2000-06-14 | 2005-12-13 | Gene Logic, Inc. | Gene expression profiles in liver cancer |
JP2004512824A (ja) * | 2000-07-11 | 2004-04-30 | コリクサ コーポレイション | 肺癌の治療および診断のための組成物および方法 |
US20070015148A1 (en) * | 2001-01-25 | 2007-01-18 | Orr Michael S | Gene expression profiles in breast tissue |
CN100578227C (zh) * | 2001-02-21 | 2010-01-06 | 诺华疫苗和诊断公司 | 用于诊断和作为癌症治疗靶标的ttk |
AU2002258518A1 (en) * | 2001-03-14 | 2002-09-24 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer |
CA2444691A1 (en) * | 2001-04-18 | 2002-10-31 | Protein Design Labs, Inc. | Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer |
JP4658936B2 (ja) * | 2004-03-24 | 2011-03-23 | オンコセラピー・サイエンス株式会社 | 肺癌を治療するための組成物および方法 |
DK2325305T3 (en) * | 2005-02-25 | 2014-03-03 | Oncotherapy Science Inc | Peptide vaccines for cancers that express TTK-, URLC10- or KOC1 polypeptide |
EP2423333A1 (de) * | 2006-08-25 | 2012-02-29 | Oncotherapy Science, Inc. | Prognosemarker und therapeutische Targets für Lungenkrebs |
BRPI0815769A2 (pt) * | 2007-08-24 | 2017-08-08 | Oncotherapy Science Inc | Ebi3, dlx5, nptx1 e cdkn3 como genes alvo da terapia e diagnóstico de câncer de pulmão |
-
2003
- 2003-09-15 TW TW092125317A patent/TW200413725A/zh unknown
- 2003-09-22 AT AT06022167T patent/ATE541053T1/de active
- 2003-09-22 EP EP10010313A patent/EP2270499A1/de not_active Withdrawn
- 2003-09-22 EP EP10010309A patent/EP2264190A1/de not_active Withdrawn
- 2003-09-22 EP EP10010330A patent/EP2270222A2/de not_active Withdrawn
- 2003-09-22 EP EP10010310A patent/EP2264457A1/de not_active Withdrawn
- 2003-09-22 KR KR1020057005561A patent/KR101075158B1/ko not_active IP Right Cessation
- 2003-09-22 CA CA002500151A patent/CA2500151A1/en not_active Abandoned
- 2003-09-22 EP EP10010328A patent/EP2270220A3/de not_active Withdrawn
- 2003-09-22 EP EP10010333A patent/EP2270225A3/de not_active Withdrawn
- 2003-09-22 JP JP2004541231A patent/JP4425141B2/ja not_active Expired - Fee Related
- 2003-09-22 EP EP10010314A patent/EP2270500A1/de not_active Withdrawn
- 2003-09-22 EP EP10010307A patent/EP2264186A1/de not_active Withdrawn
- 2003-09-22 EP EP10010329A patent/EP2270221A3/de not_active Withdrawn
- 2003-09-22 EP EP10010332A patent/EP2270224A3/de not_active Withdrawn
- 2003-09-22 EP EP10010311A patent/EP2278028A1/de not_active Withdrawn
- 2003-09-22 EP EP10010306A patent/EP2264185A1/de not_active Withdrawn
- 2003-09-22 EP EP10010318A patent/EP2270210A3/de not_active Withdrawn
- 2003-09-22 EP EP10010316A patent/EP2270502A3/de not_active Withdrawn
- 2003-09-22 EP EP10010320A patent/EP2270212A3/de not_active Withdrawn
- 2003-09-22 EP EP06022167A patent/EP1743947B1/de not_active Expired - Lifetime
- 2003-09-22 EP EP10010312A patent/EP2270498A3/de not_active Withdrawn
- 2003-09-22 EP EP10010322A patent/EP2270214A3/de not_active Withdrawn
- 2003-09-22 EP EP10010327A patent/EP2270219A3/de not_active Withdrawn
- 2003-09-22 EP EP10010321A patent/EP2270213A3/de not_active Withdrawn
- 2003-09-22 AU AU2003272088A patent/AU2003272088A1/en not_active Abandoned
- 2003-09-22 EP EP10010308A patent/EP2264187A1/de not_active Withdrawn
- 2003-09-22 EP EP10010325A patent/EP2270217A3/de not_active Withdrawn
- 2003-09-22 EP EP10010331A patent/EP2270223A2/de not_active Withdrawn
- 2003-09-22 EP EP10010319A patent/EP2270211A3/de not_active Withdrawn
- 2003-09-22 EP EP10010315A patent/EP2270501A3/de not_active Withdrawn
- 2003-09-22 EP EP10010324A patent/EP2270216A3/de not_active Withdrawn
- 2003-09-22 KR KR1020117003536A patent/KR20110020953A/ko active IP Right Grant
- 2003-09-22 EP EP10010317A patent/EP2270503A3/de not_active Withdrawn
- 2003-09-22 WO PCT/JP2003/012072 patent/WO2004031413A2/en not_active Application Discontinuation
- 2003-09-22 EP EP03753941A patent/EP1551998A2/de not_active Withdrawn
- 2003-09-22 EP EP10010323A patent/EP2270215A3/de not_active Withdrawn
- 2003-09-22 EP EP10010326A patent/EP2270218A2/de not_active Withdrawn
-
2009
- 2009-06-09 JP JP2009138122A patent/JP4921522B2/ja not_active Expired - Fee Related
- 2009-10-05 JP JP2009231138A patent/JP2010042016A/ja active Pending
-
2012
- 2012-01-11 JP JP2012003039A patent/JP2012125247A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE541053T1 (de) | Verfahren und zusammensetzungen zur behandlung von nichtkleinzelligem lungenkrebs | |
ATE519862T1 (de) | Zusammensetzungen, kits und verfahren zur identifizierung, beurteilung, vorbeugung und therapie von gebärmutterhalskrebs | |
ATE511503T1 (de) | Aryl- und heteroarylharnstoff-chk1-inhibitoren zur verwendung als radiosensibilisatoren und chemosensibilisatoren | |
DE69921156D1 (de) | Verwendung von 5ht-6 antagonisten zur behandlung adhd | |
WO2003004989A3 (en) | Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer | |
ATE540129T1 (de) | Target zur therapie kognitiver behinderungen | |
DE602004015064D1 (de) | Zusammensetzungen und verfahren zur diagnose und behandlung von kolonkrebs | |
ATE522623T1 (de) | Zusammensetzungen und verfahren zur behandlung und diagnose von lungentumoren | |
WO2003009814A3 (en) | Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer | |
WO2004106495A3 (en) | Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer | |
DE69911210D1 (de) | Verwendung von piperin und derivate davon zur behandlung von hautpigmentierungstörungen und hautkrebs | |
ATE415962T1 (de) | Verwendung von asiatsäure oder asiaticosid zur behandlung von krebs | |
ATE260282T1 (de) | Aromatische ester von camptothecinen und verfahren zur behandlung von krebserkrankungen | |
DE60021381D1 (de) | Chinonverbindungen zur behandlung von krankheiten | |
WO2005000335A3 (en) | Use of genes differentially expressed during aging of liver for treatment and diagnosis | |
MXPA05014220A (es) | Genes regulados en cancer ovarico como objetivos de pronostico y terapeuticos. | |
ATE423780T1 (de) | Makrozyclen zur behandlung von krebserkrankungen | |
DE60334289D1 (de) | Dithiolopyrrolon-derivate zur behandlung von proliferativen störungen | |
DE60020591D1 (de) | Benzenoidderivate von 15-hydroxyeicosatetraensäure und verfahren zur verwendung zur behandlung des trockenen auges | |
ATE397003T1 (de) | Ruthenium(ii)-komplexe zur behandlung von tumoren | |
ATE411313T1 (de) | Neue makrocyclen zur behandlung von krebserkrankungen |