ATE423780T1 - Makrozyclen zur behandlung von krebserkrankungen - Google Patents
Makrozyclen zur behandlung von krebserkrankungenInfo
- Publication number
- ATE423780T1 ATE423780T1 AT03763870T AT03763870T ATE423780T1 AT E423780 T1 ATE423780 T1 AT E423780T1 AT 03763870 T AT03763870 T AT 03763870T AT 03763870 T AT03763870 T AT 03763870T AT E423780 T1 ATE423780 T1 AT E423780T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- macrocycles
- cancer diseases
- cancer
- diseases
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- 150000002678 macrocyclic compounds Chemical class 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/26—Radicals substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/06—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10232094A DE10232094A1 (de) | 2002-07-15 | 2002-07-15 | 5-Thiaepothilone und 15-disubstituierte Epothilone |
| DE10255660A DE10255660A1 (de) | 2002-11-28 | 2002-11-28 | Neue Makrocyclen zur Behandlung von Krebserkrankungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE423780T1 true ATE423780T1 (de) | 2009-03-15 |
Family
ID=30116646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03763870T ATE423780T1 (de) | 2002-07-15 | 2003-07-15 | Makrozyclen zur behandlung von krebserkrankungen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7553859B2 (de) |
| EP (1) | EP1521752B1 (de) |
| JP (1) | JP4597667B2 (de) |
| AT (1) | ATE423780T1 (de) |
| AU (1) | AU2003252540B2 (de) |
| CA (1) | CA2491943C (de) |
| DE (1) | DE60326348D1 (de) |
| DK (1) | DK1521752T3 (de) |
| ES (1) | ES2323956T3 (de) |
| WO (1) | WO2004007492A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1567524T3 (da) * | 2002-11-28 | 2009-11-16 | Wolfgang Richter | Thia-epothilonderivater til behandling af cancer |
| MX2010011209A (es) | 2008-04-24 | 2010-11-12 | Squibb Bristol Myers Co | Uso de epotilona d en el tratamiento de enfermedades asociadas a tau incluyendo enfermedad de alzheimer. |
| EP2394640A1 (de) | 2010-05-21 | 2011-12-14 | MediGene AG | Verbesserte liposomale Formulierungen von lipophilen Verbindungen |
| EP2708243A1 (de) | 2012-09-17 | 2014-03-19 | OntoChem GmbH | Rezeptor-Ligand-verbundene zytotoxische Moleküle |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004500388A (ja) * | 2000-03-01 | 2004-01-08 | スローン−ケッタリング インスティトュート フォア キャンサー リサーチ | エポチロン、その中間体およびその類似体の合成 |
| HRP20030027A2 (en) * | 2000-06-28 | 2004-02-29 | Teva Pharma | Carvedilol |
| DK1567524T3 (da) * | 2002-11-28 | 2009-11-16 | Wolfgang Richter | Thia-epothilonderivater til behandling af cancer |
-
2003
- 2003-07-15 EP EP03763870A patent/EP1521752B1/de not_active Expired - Lifetime
- 2003-07-15 DE DE60326348T patent/DE60326348D1/de not_active Expired - Lifetime
- 2003-07-15 AU AU2003252540A patent/AU2003252540B2/en not_active Ceased
- 2003-07-15 ES ES03763870T patent/ES2323956T3/es not_active Expired - Lifetime
- 2003-07-15 WO PCT/EP2003/007664 patent/WO2004007492A1/de not_active Ceased
- 2003-07-15 US US10/520,769 patent/US7553859B2/en not_active Expired - Fee Related
- 2003-07-15 JP JP2004520647A patent/JP4597667B2/ja not_active Expired - Fee Related
- 2003-07-15 DK DK03763870T patent/DK1521752T3/da active
- 2003-07-15 AT AT03763870T patent/ATE423780T1/de not_active IP Right Cessation
- 2003-07-15 CA CA2491943A patent/CA2491943C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE60326348D1 (de) | 2009-04-09 |
| JP2005537263A (ja) | 2005-12-08 |
| DK1521752T3 (da) | 2009-06-22 |
| AU2003252540B2 (en) | 2008-11-20 |
| AU2003252540A1 (en) | 2004-02-02 |
| EP1521752B1 (de) | 2009-02-25 |
| CA2491943C (en) | 2012-06-19 |
| US7553859B2 (en) | 2009-06-30 |
| US20060004065A1 (en) | 2006-01-05 |
| ES2323956T3 (es) | 2009-07-28 |
| WO2004007492A1 (de) | 2004-01-22 |
| JP4597667B2 (ja) | 2010-12-15 |
| EP1521752A1 (de) | 2005-04-13 |
| CA2491943A1 (en) | 2004-01-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE50310516D1 (de) | Fredericamycin-derivate | |
| ATE442142T1 (de) | Fredericamycin-derivate als arzneimittel zur tumorbehandlung | |
| EA200802213A1 (ru) | Способы лечения заболеваний крови | |
| EA200900802A1 (ru) | Способы и композиции для лечения амилоидных заболеваний | |
| EA200600078A1 (ru) | Способы и композиции для лечения амилоидных заболеваний | |
| ATE414089T1 (de) | Verwendung von rapamycin und dessen derivaten zur behandlung von knochenverlust | |
| BRPI0418251A (pt) | fosfonatos, monofosfonamidatos, bisfosfonamidatos para o tratamento de doenças virais | |
| TW200510325A (en) | 2-acylamino-4-phenylthiazole derivatives, preparation thereof and therapeutic application thereof | |
| ATE453653T1 (de) | Platinkomplexe zur behandlung von tumoren | |
| TW200509892A (en) | Novel aminobenzophenone compounds | |
| ATE448232T1 (de) | Substituierte heterozyklen | |
| DE60021381D1 (de) | Chinonverbindungen zur behandlung von krankheiten | |
| ATE443704T1 (de) | Pyridopyrimidinone zur behandlung von krebserkrankungen | |
| NO20055741D0 (no) | Nye kjemiske forbindelser | |
| SE0302304D0 (sv) | Novel compounds | |
| DE602004021363D1 (de) | Imidazotriazin verbindungen zur behandlung von krebserkrankungen | |
| DE60131968D1 (de) | PYRANOÄ2,3-cÜIMIDAZOÄ1,2-aÜPYRIDIN-DERIVATE ZUR BEHANDLUNG VON GASTROINTESTINALEN ERKRANKUNGEN | |
| DE602004019541D1 (de) | Cycloalkyläbü kondensierte indole | |
| BRPI0415355A (pt) | triarilimidazóis | |
| ATE423780T1 (de) | Makrozyclen zur behandlung von krebserkrankungen | |
| DK1596879T3 (da) | Anvendelse af kahalalidforbindelser til fremstilling af et medikament til behandling af psoriasis | |
| EA200600115A1 (ru) | Производные 2-аминобензойной кислоты | |
| ATE536874T1 (de) | Dreifache monoamin-wiederaufnahmehemmer zur behandlung von chronischen schmerzen | |
| EA200501259A1 (ru) | Комбинированное применение фибрата и орлистата для лечения ожирения | |
| ATE431348T1 (de) | Thiaepothilone zur behandlung von krebserkrankungen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEFA | Change of the company name | ||
| UEP | Publication of translation of european patent specification |
Ref document number: 1521752 Country of ref document: EP |
|
| UEP | Publication of translation of european patent specification |
Ref document number: 1521752 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |