DE602004021363D1 - Imidazotriazin verbindungen zur behandlung von krebserkrankungen - Google Patents

Imidazotriazin verbindungen zur behandlung von krebserkrankungen

Info

Publication number
DE602004021363D1
DE602004021363D1 DE602004021363T DE602004021363T DE602004021363D1 DE 602004021363 D1 DE602004021363 D1 DE 602004021363D1 DE 602004021363 T DE602004021363 T DE 602004021363T DE 602004021363 T DE602004021363 T DE 602004021363T DE 602004021363 D1 DE602004021363 D1 DE 602004021363D1
Authority
DE
Germany
Prior art keywords
compounds
imidazotriazin
treatment
cancer diseases
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004021363T
Other languages
English (en)
Inventor
Mui Cheung
Nigel Paul King
Kevin Wayne Kuntz
Robert Anthony Mook Jr
Mark Andrew Pobanz
James Michael Salovich
Brian John Wilson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of DE602004021363D1 publication Critical patent/DE602004021363D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE602004021363T 2003-04-01 2004-03-29 Imidazotriazin verbindungen zur behandlung von krebserkrankungen Expired - Lifetime DE602004021363D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45929303P 2003-04-01 2003-04-01
PCT/US2004/009553 WO2004087652A2 (en) 2003-04-01 2004-03-29 Imidazotriazine compounds

Publications (1)

Publication Number Publication Date
DE602004021363D1 true DE602004021363D1 (de) 2009-07-16

Family

ID=33131876

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004021363T Expired - Lifetime DE602004021363D1 (de) 2003-04-01 2004-03-29 Imidazotriazin verbindungen zur behandlung von krebserkrankungen

Country Status (7)

Country Link
US (1) US7462614B2 (de)
EP (1) EP1608656B1 (de)
JP (1) JP2006522127A (de)
AT (1) ATE432936T1 (de)
DE (1) DE602004021363D1 (de)
ES (1) ES2326808T3 (de)
WO (1) WO2004087652A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8163956B2 (en) * 2005-06-13 2012-04-24 Merck Sharp & Dohme Corp. Inhibitors of GLYT1 transporters
JP5498703B2 (ja) * 2006-01-23 2014-05-21 バーテックス ファーマシューティカルズ インコーポレイテッド プロテインキナーゼのインヒビターとして有用なチオフェン−カルボキサミド
US7504513B2 (en) 2006-02-27 2009-03-17 Hoffman-La Roche Inc. Thiazolyl-benzimidazoles
JP2009533452A (ja) 2006-04-13 2009-09-17 バーテックス ファーマシューティカルズ インコーポレイテッド タンパク質キナーゼの阻害剤として有用なチオフェン−カルボキサミド
CN101484447A (zh) 2006-05-23 2009-07-15 沃泰克斯药物股份有限公司 可用作蛋白激酶抑制剂的噻吩-甲酰胺类
CN101495474A (zh) 2006-05-23 2009-07-29 沃泰克斯药物股份有限公司 可用作蛋白激酶抑制剂的噻吩-甲酰胺类
EP2100894A1 (de) 2008-03-12 2009-09-16 4Sc Ag Pyridopyrimidinone verwendbar als Plk1 (polo-like kinase) Hemmen
SG172229A1 (en) 2008-12-18 2011-07-28 Hoffmann La Roche Thiazolyl-benzimidazoles
CN102552274B (zh) * 2010-11-12 2013-10-23 姚雪彪 动点马达蛋白小分子抑制剂在抑制肿瘤细胞增殖中的应用
CN102827022A (zh) * 2012-09-21 2012-12-19 西华大学 2-乙酰氧基-n-(4-甲氧基苯基)苯甲酰胺及其制备方法和用途
GB202018412D0 (en) * 2020-11-23 2021-01-06 Exscientia Ltd Malt-1 modulators ii

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791025A (fr) 1971-11-19 1973-05-07 Allen & Hanburys Ltd Composes heterocycliques
GB1457873A (en) 1973-01-04 1976-12-08 Allen & Hanburys Ltd Imidazotriazines
DK109578A (da) 1977-03-25 1978-09-26 Allen & Hanburys Ltd Fremgangsmaade til fremstilling af heterocycliske forbindelser
US4308384A (en) 1978-09-18 1981-12-29 Glaxo Group Limited Production of triazinones
JPS59164553A (ja) 1983-03-08 1984-09-17 Fuji Photo Film Co Ltd カラ−写真感光材料
US4838925A (en) 1986-04-25 1989-06-13 E. I. Du Pont De Nemours And Company Heterocyclic acyl sulfonamides
BR9812785A (pt) 1997-11-12 2000-10-10 Bayer Ag "imidazotriazinonas 2-fenil-substituìdas como inibidores de fosfodiesterase"
DE10011530A1 (de) 2000-03-13 2001-09-27 Robert Elez Hochwirksame Antisense-Oligodesoxynucleotide gegen Polio-like Kinasel
DE10230604A1 (de) 2002-07-08 2004-01-29 Bayer Ag Heterocyclisch substituierte Imidazotriazine

Also Published As

Publication number Publication date
US7462614B2 (en) 2008-12-09
WO2004087652A2 (en) 2004-10-14
EP1608656B1 (de) 2009-06-03
ES2326808T3 (es) 2009-10-20
JP2006522127A (ja) 2006-09-28
WO2004087652A3 (en) 2005-02-10
US20060217382A1 (en) 2006-09-28
EP1608656A2 (de) 2005-12-28
ATE432936T1 (de) 2009-06-15

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