TW200413725A - Method for diagnosing non-small cell lung cancers - Google Patents

Info

Publication number

TW200413725A

TW200413725A TW092125317A TW92125317A TW200413725A TW 200413725 A TW200413725 A TW 200413725A TW 092125317 A TW092125317 A TW 092125317A TW 92125317 A TW92125317 A TW 92125317A TW 200413725 A TW200413725 A TW 200413725A

Authority

TW

Taiwan

Prior art keywords

nsc

protein

lung cancer

small cell

gene

Prior art date

2002-09-30

Links

• Espacenet
• Global Dossier
• Discuss

• 208000002154 non-small cell lung carcinoma Diseases 0.000 title claims abstract description 152
• 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 title claims abstract description 149
• 238000000034 method Methods 0.000 title claims abstract description 141
• 108090000623 proteins and genes Proteins 0.000 claims abstract description 466
• 150000001875 compounds Chemical class 0.000 claims abstract description 104
• 230000014509 gene expression Effects 0.000 claims abstract description 78
• 102000004169 proteins and genes Human genes 0.000 claims description 232
• 210000004027 cell Anatomy 0.000 claims description 184
• 108090000765 processed proteins & peptides Proteins 0.000 claims description 168
• 102000004196 processed proteins & peptides Human genes 0.000 claims description 140
• 229920001184 polypeptide Polymers 0.000 claims description 123
• 238000012360 testing method Methods 0.000 claims description 86
• 206010028980 Neoplasm Diseases 0.000 claims description 63
• 102000040430 polynucleotide Human genes 0.000 claims description 50
• 108091033319 polynucleotide Proteins 0.000 claims description 50
• 201000011510 cancer Diseases 0.000 claims description 48
• 108020004414 DNA Proteins 0.000 claims description 43
• 239000002157 polynucleotide Substances 0.000 claims description 42
• 230000000694 effects Effects 0.000 claims description 39
• 208000020816 lung neoplasm Diseases 0.000 claims description 37
• 206010058467 Lung neoplasm malignant Diseases 0.000 claims description 36
• 201000005202 lung cancer Diseases 0.000 claims description 36
• 238000011282 treatment Methods 0.000 claims description 36
• 239000002253 acid Substances 0.000 claims description 35
• 239000000203 mixture Substances 0.000 claims description 35
• 239000012634 fragment Substances 0.000 claims description 34
• 230000027455 binding Effects 0.000 claims description 30
• 230000000295 complement effect Effects 0.000 claims description 27
• 238000012216 screening Methods 0.000 claims description 27
• 239000012472 biological sample Substances 0.000 claims description 26
• 239000002773 nucleotide Substances 0.000 claims description 24
• 125000003729 nucleotide group Chemical group 0.000 claims description 24
• 239000003550 marker Substances 0.000 claims description 23
• 230000004071 biological effect Effects 0.000 claims description 19
• 210000000612 antigen-presenting cell Anatomy 0.000 claims description 17
• 150000001413 amino acids Chemical class 0.000 claims description 16
• 229960005486 vaccine Drugs 0.000 claims description 16
• 125000003275 alpha amino acid group Chemical group 0.000 claims description 15
• 230000000692 anti-sense effect Effects 0.000 claims description 14
• 238000001514 detection method Methods 0.000 claims description 14
• 239000013598 vector Substances 0.000 claims description 14
• 108091028043 Nucleic acid sequence Proteins 0.000 claims description 13
• 108700008625 Reporter Genes Proteins 0.000 claims description 13
• 239000003814 drug Substances 0.000 claims description 13
• 230000005809 anti-tumor immunity Effects 0.000 claims description 12
• 230000002265 prevention Effects 0.000 claims description 12
• 239000003112 inhibitor Substances 0.000 claims description 11
• 239000004480 active ingredient Substances 0.000 claims description 10
• 230000007423 decrease Effects 0.000 claims description 10
• 108020004459 Small interfering RNA Proteins 0.000 claims description 9
• 238000011161 development Methods 0.000 claims description 9
• 229940079593 drug Drugs 0.000 claims description 9
• 230000001939 inductive effect Effects 0.000 claims description 9
• 210000004072 lung Anatomy 0.000 claims description 9
• 230000004663 cell proliferation Effects 0.000 claims description 8
• 230000001225 therapeutic effect Effects 0.000 claims description 8
• 239000003153 chemical reaction reagent Substances 0.000 claims description 7
• 238000009396 hybridization Methods 0.000 claims description 7
• 230000001965 increasing effect Effects 0.000 claims description 7
• 239000008194 pharmaceutical composition Substances 0.000 claims description 7
• 210000004369 blood Anatomy 0.000 claims description 6
• 239000008280 blood Substances 0.000 claims description 6
• 239000003623 enhancer Substances 0.000 claims description 6
• 238000001727 in vivo Methods 0.000 claims description 6
• 210000003205 muscle Anatomy 0.000 claims description 6
• 230000028327 secretion Effects 0.000 claims description 6
• GOJUJUVQIVIZAV-UHFFFAOYSA-N 2-amino-4,6-dichloropyrimidine-5-carbaldehyde Chemical group NC1=NC(Cl)=C(C=O)C(Cl)=N1 GOJUJUVQIVIZAV-UHFFFAOYSA-N 0.000 claims description 4
• XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 4
• 241000282320 Panthera leo Species 0.000 claims description 4
• 206010041067 Small cell lung cancer Diseases 0.000 claims description 4
• 230000003993 interaction Effects 0.000 claims description 4
• 208000000587 small cell lung carcinoma Diseases 0.000 claims description 4
• 239000000126 substance Substances 0.000 claims description 4
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 3
• 238000012258 culturing Methods 0.000 claims description 3
• 239000003937 drug carrier Substances 0.000 claims description 2
• 229910052742 iron Inorganic materials 0.000 claims description 2
• 102000054765 polymorphisms of proteins Human genes 0.000 claims description 2
• 230000009467 reduction Effects 0.000 claims description 2
• ITUYMTWJWYTELW-UHFFFAOYSA-N 4-chloroiminocyclohexa-2,5-dien-1-one Chemical compound ClN=C1C=CC(=O)C=C1 ITUYMTWJWYTELW-UHFFFAOYSA-N 0.000 claims 1
• 108091026890 Coding region Proteins 0.000 claims 1
• 101000883798 Homo sapiens Probable ATP-dependent RNA helicase DDX53 Proteins 0.000 claims 1
• 101100545275 Mus musculus Znf106 gene Proteins 0.000 claims 1
• 102100038236 Probable ATP-dependent RNA helicase DDX53 Human genes 0.000 claims 1
• 206010036790 Productive cough Diseases 0.000 claims 1
• 229920000642 polymer Polymers 0.000 claims 1
• 238000009958 sewing Methods 0.000 claims 1
• 210000003802 sputum Anatomy 0.000 claims 1
• 208000024794 sputum Diseases 0.000 claims 1
• 241000282414 Homo sapiens Species 0.000 abstract description 197
• 235000018102 proteins Nutrition 0.000 description 225
• 108020004635 Complementary DNA Proteins 0.000 description 93
• 239000002299 complementary DNA Substances 0.000 description 82
• 238000010804 cDNA synthesis Methods 0.000 description 79
• 102000039446 nucleic acids Human genes 0.000 description 55
• 108020004707 nucleic acids Proteins 0.000 description 55
• 150000007523 nucleic acids Chemical class 0.000 description 52
• 229940088598 enzyme Drugs 0.000 description 41
• 102000004190 Enzymes Human genes 0.000 description 40
• 108090000790 Enzymes Proteins 0.000 description 40
• 229920002477 rna polymer Polymers 0.000 description 40
• 108020004999 messenger RNA Proteins 0.000 description 32
• 239000000047 product Substances 0.000 description 32
• 102000005962 receptors Human genes 0.000 description 30
• 108020003175 receptors Proteins 0.000 description 30
• 239000000523 sample Substances 0.000 description 29
• 230000001105 regulatory effect Effects 0.000 description 24
• 235000013601 eggs Nutrition 0.000 description 23
• 108091032973 (ribonucleotides)n+m Proteins 0.000 description 22
• 102000036639 antigens Human genes 0.000 description 21
• 239000000427 antigen Substances 0.000 description 20
• 108091007433 antigens Proteins 0.000 description 20
• 239000003795 chemical substances by application Substances 0.000 description 20
• 102000014914 Carrier Proteins Human genes 0.000 description 18
• 230000006870 function Effects 0.000 description 18
• 210000001519 tissue Anatomy 0.000 description 17
• 235000001014 amino acid Nutrition 0.000 description 16
• 108091008324 binding proteins Proteins 0.000 description 16
• 230000002401 inhibitory effect Effects 0.000 description 16
• 229940024606 amino acid Drugs 0.000 description 15
• 230000033228 biological regulation Effects 0.000 description 14
• 238000011109 contamination Methods 0.000 description 13
• 210000000349 chromosome Anatomy 0.000 description 12
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 12
• 210000004443 dendritic cell Anatomy 0.000 description 11
• 201000010099 disease Diseases 0.000 description 11
• 238000013518 transcription Methods 0.000 description 11
• 240000004808 Saccharomyces cerevisiae Species 0.000 description 10
• 210000001151 cytotoxic T lymphocyte Anatomy 0.000 description 10
• 108020001507 fusion proteins Proteins 0.000 description 10
• 102000037865 fusion proteins Human genes 0.000 description 10
• 101710088194 Dehydrogenase Proteins 0.000 description 9
• 102000001253 Protein Kinase Human genes 0.000 description 9
• 239000000074 antisense oligonucleotide Substances 0.000 description 9
• 238000012230 antisense oligonucleotides Methods 0.000 description 9
• 210000003819 peripheral blood mononuclear cell Anatomy 0.000 description 9
• 239000002243 precursor Substances 0.000 description 9
• 108060006633 protein kinase Proteins 0.000 description 9
• 230000035897 transcription Effects 0.000 description 9
• 210000004881 tumor cell Anatomy 0.000 description 9
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
• UYTPUPDQBNUYGX-UHFFFAOYSA-N Guanine Natural products O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 description 8
• 108091034117 Oligonucleotide Proteins 0.000 description 8
• 108700020796 Oncogene Proteins 0.000 description 8
• 230000018109 developmental process Effects 0.000 description 8
• -1 guanine Nucleic acid Chemical class 0.000 description 8
• 230000036961 partial effect Effects 0.000 description 8
• 239000013074 reference sample Substances 0.000 description 8
• 102000053602 DNA Human genes 0.000 description 7
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 7
• 108060003951 Immunoglobulin Proteins 0.000 description 7
• 230000004913 activation Effects 0.000 description 7
• 230000015572 biosynthetic process Effects 0.000 description 7
• 230000001419 dependent effect Effects 0.000 description 7
• 102000018358 immunoglobulin Human genes 0.000 description 7
• 239000007924 injection Substances 0.000 description 7
• 238000002347 injection Methods 0.000 description 7
• 210000002540 macrophage Anatomy 0.000 description 7
• 239000011159 matrix material Substances 0.000 description 7
• 239000012528 membrane Substances 0.000 description 7
• 210000004940 nucleus Anatomy 0.000 description 7
• 239000012071 phase Substances 0.000 description 7
• 238000000018 DNA microarray Methods 0.000 description 6
• QTBSBXVTEAMEQO-UHFFFAOYSA-N acetic acid Substances CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
• 230000008859 change Effects 0.000 description 6
• 238000005516 engineering process Methods 0.000 description 6
• RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 description 6
• 239000005556 hormone Substances 0.000 description 6
• 229940088597 hormone Drugs 0.000 description 6
• 238000009169 immunotherapy Methods 0.000 description 6
• 238000000338 in vitro Methods 0.000 description 6
• 210000005265 lung cell Anatomy 0.000 description 6
• 210000004698 lymphocyte Anatomy 0.000 description 6
• 238000004519 manufacturing process Methods 0.000 description 6
• 230000004048 modification Effects 0.000 description 6
• 238000012986 modification Methods 0.000 description 6
• 238000004393 prognosis Methods 0.000 description 6
• 239000007787 solid Substances 0.000 description 6
• 239000000243 solution Substances 0.000 description 6
• 239000000758 substrate Substances 0.000 description 6
• 230000004083 survival effect Effects 0.000 description 6
• 235000012431 wafers Nutrition 0.000 description 6
• 241000255581 Drosophila <fruit fly, genus> Species 0.000 description 5
• 102000030782 GTP binding Human genes 0.000 description 5
• 108091000058 GTP-Binding Proteins 0.000 description 5
• 102000004157 Hydrolases Human genes 0.000 description 5
• 108090000604 Hydrolases Proteins 0.000 description 5
• 102000004316 Oxidoreductases Human genes 0.000 description 5
• 108090000854 Oxidoreductases Proteins 0.000 description 5
• 108091000080 Phosphotransferase Proteins 0.000 description 5
• 108010029485 Protein Isoforms Proteins 0.000 description 5
• 102000001708 Protein Isoforms Human genes 0.000 description 5
• 210000001744 T-lymphocyte Anatomy 0.000 description 5
• 241000700605 Viruses Species 0.000 description 5
• 230000000259 anti-tumor effect Effects 0.000 description 5
• 238000004891 communication Methods 0.000 description 5
• 235000018417 cysteine Nutrition 0.000 description 5
• XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 description 5
• 238000012217 deletion Methods 0.000 description 5
• 230000037430 deletion Effects 0.000 description 5
• 239000000284 extract Substances 0.000 description 5
• 208000032839 leukemia Diseases 0.000 description 5
• 230000035772 mutation Effects 0.000 description 5
• 230000002018 overexpression Effects 0.000 description 5
• 102000020233 phosphotransferase Human genes 0.000 description 5
• 239000000843 powder Substances 0.000 description 5
• 230000011664 signaling Effects 0.000 description 5
• 102000040650 (ribonucleotides)n+m Human genes 0.000 description 4
• ASJSAQIRZKANQN-CRCLSJGQSA-N 2-deoxy-D-ribose Chemical compound OC[C@@H](O)[C@@H](O)CC=O ASJSAQIRZKANQN-CRCLSJGQSA-N 0.000 description 4
• 108010078791 Carrier Proteins Proteins 0.000 description 4
• 102000004127 Cytokines Human genes 0.000 description 4
• 108090000695 Cytokines Proteins 0.000 description 4
• HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 description 4
• LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 4
• 108091006027 G proteins Proteins 0.000 description 4
• 102000006395 Globulins Human genes 0.000 description 4
• 108010044091 Globulins Proteins 0.000 description 4
• 102000003886 Glycoproteins Human genes 0.000 description 4
• 108090000288 Glycoproteins Proteins 0.000 description 4
• 241000282412 Homo Species 0.000 description 4
• 101001012157 Homo sapiens Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 description 4
• 108010021625 Immunoglobulin Fragments Proteins 0.000 description 4
• 102000008394 Immunoglobulin Fragments Human genes 0.000 description 4
• ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 description 4
• 102000018697 Membrane Proteins Human genes 0.000 description 4
• 108010052285 Membrane Proteins Proteins 0.000 description 4
• 102000005741 Metalloproteases Human genes 0.000 description 4
• 108010006035 Metalloproteases Proteins 0.000 description 4
• 102000007999 Nuclear Proteins Human genes 0.000 description 4
• 108010089610 Nuclear Proteins Proteins 0.000 description 4
• ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 description 4
• 241000700159 Rattus Species 0.000 description 4
• 102100030086 Receptor tyrosine-protein kinase erbB-2 Human genes 0.000 description 4
• 108700005075 Regulator Genes Proteins 0.000 description 4
• 102100027609 Rho-related GTP-binding protein RhoD Human genes 0.000 description 4
• PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 description 4
• MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 description 4
• 238000001042 affinity chromatography Methods 0.000 description 4
• HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 description 4
• 239000011575 calcium Substances 0.000 description 4
• 230000001413 cellular effect Effects 0.000 description 4
• 238000006356 dehydrogenation reaction Methods 0.000 description 4
• 238000003745 diagnosis Methods 0.000 description 4
• 238000010494 dissociation reaction Methods 0.000 description 4
• 230000005593 dissociations Effects 0.000 description 4
• 238000011156 evaluation Methods 0.000 description 4
• 239000013604 expression vector Substances 0.000 description 4
• 239000008187 granular material Substances 0.000 description 4
• 230000012010 growth Effects 0.000 description 4
• 239000004615 ingredient Substances 0.000 description 4
• 210000000265 leukocyte Anatomy 0.000 description 4
• 201000001441 melanoma Diseases 0.000 description 4
• 210000002569 neuron Anatomy 0.000 description 4
• 238000003752 polymerase chain reaction Methods 0.000 description 4
• 238000002360 preparation method Methods 0.000 description 4
• 210000002460 smooth muscle Anatomy 0.000 description 4
• 230000004936 stimulating effect Effects 0.000 description 4
• 238000003786 synthesis reaction Methods 0.000 description 4
• 230000002103 transcriptional effect Effects 0.000 description 4
• 238000010396 two-hybrid screening Methods 0.000 description 4
• 102100024092 Aldo-keto reductase family 1 member C4 Human genes 0.000 description 3
• 208000005623 Carcinogenesis Diseases 0.000 description 3
• 108090000994 Catalytic RNA Proteins 0.000 description 3
• 102000053642 Catalytic RNA Human genes 0.000 description 3
• 108010012236 Chemokines Proteins 0.000 description 3
• 102000019034 Chemokines Human genes 0.000 description 3
• 108090000197 Clusterin Proteins 0.000 description 3
• 102000003780 Clusterin Human genes 0.000 description 3
• 102000008186 Collagen Human genes 0.000 description 3
• 108010035532 Collagen Proteins 0.000 description 3
• 102100035218 Epidermal growth factor receptor kinase substrate 8-like protein 2 Human genes 0.000 description 3
• 108010024636 Glutathione Proteins 0.000 description 3
• 102100034294 Glutathione synthetase Human genes 0.000 description 3
• 101000924727 Homo sapiens Alternative prion protein Proteins 0.000 description 3
• 101000876686 Homo sapiens Epidermal growth factor receptor kinase substrate 8-like protein 2 Proteins 0.000 description 3
• 101001069973 Homo sapiens Glutathione synthetase Proteins 0.000 description 3
• 101000573901 Homo sapiens Major prion protein Proteins 0.000 description 3
• 101000958041 Homo sapiens Musculin Proteins 0.000 description 3
• 101150080778 INPP5D gene Proteins 0.000 description 3
• 108700018351 Major Histocompatibility Complex Proteins 0.000 description 3
• 241000124008 Mammalia Species 0.000 description 3
• 241001465754 Metazoa Species 0.000 description 3
• 241000699670 Mus sp. Species 0.000 description 3
• 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 description 3
• 241000283973 Oryctolagus cuniculus Species 0.000 description 3
• 102000035195 Peptidases Human genes 0.000 description 3
• 108091005804 Peptidases Proteins 0.000 description 3
• 108090000708 Proteasome Endopeptidase Complex Proteins 0.000 description 3
• 102000004245 Proteasome Endopeptidase Complex Human genes 0.000 description 3
• 102000004022 Protein-Tyrosine Kinases Human genes 0.000 description 3
• 108090000412 Protein-Tyrosine Kinases Proteins 0.000 description 3
• 108010083644 Ribonucleases Proteins 0.000 description 3
• 102000006382 Ribonucleases Human genes 0.000 description 3
• 102000004389 Ribonucleoproteins Human genes 0.000 description 3
• 108010081734 Ribonucleoproteins Proteins 0.000 description 3
• 102100037942 Suppressor of tumorigenicity 14 protein Human genes 0.000 description 3
• 208000009956 adenocarcinoma Diseases 0.000 description 3
• SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 description 3
• 150000001412 amines Chemical class 0.000 description 3
• 210000004102 animal cell Anatomy 0.000 description 3
• 238000010171 animal model Methods 0.000 description 3
• 239000005557 antagonist Substances 0.000 description 3
• 239000002246 antineoplastic agent Substances 0.000 description 3
• 238000003491 array Methods 0.000 description 3
• 210000000988 bone and bone Anatomy 0.000 description 3
• 230000036952 cancer formation Effects 0.000 description 3
• 231100000504 carcinogenesis Toxicity 0.000 description 3
• 108010007169 creatine transporter Proteins 0.000 description 3
• 231100000135 cytotoxicity Toxicity 0.000 description 3
• 230000003013 cytotoxicity Effects 0.000 description 3
• 238000006392 deoxygenation reaction Methods 0.000 description 3
• 210000002919 epithelial cell Anatomy 0.000 description 3
• 238000001125 extrusion Methods 0.000 description 3
• 230000004927 fusion Effects 0.000 description 3
• 210000004907 gland Anatomy 0.000 description 3
• 230000000762 glandular Effects 0.000 description 3
• 229960003180 glutathione Drugs 0.000 description 3
• 150000003278 haem Chemical class 0.000 description 3
• 102000046949 human MSC Human genes 0.000 description 3
• 230000028993 immune response Effects 0.000 description 3
• 230000036039 immunity Effects 0.000 description 3
• 238000001114 immunoprecipitation Methods 0.000 description 3
• 239000003446 ligand Substances 0.000 description 3
• 150000002632 lipids Chemical class 0.000 description 3
• 239000000137 peptide hydrolase inhibitor Substances 0.000 description 3
• 230000000865 phosphorylative effect Effects 0.000 description 3
• 210000002307 prostate Anatomy 0.000 description 3
• 230000006798 recombination Effects 0.000 description 3
• 238000011160 research Methods 0.000 description 3
• 229930002330 retinoic acid Natural products 0.000 description 3
• 108091092562 ribozyme Proteins 0.000 description 3
• 150000003839 salts Chemical class 0.000 description 3
• 238000002416 scanning tunnelling spectroscopy Methods 0.000 description 3
• 230000003248 secreting effect Effects 0.000 description 3
• 230000035939 shock Effects 0.000 description 3
• 208000000649 small cell carcinoma Diseases 0.000 description 3
• 238000006467 substitution reaction Methods 0.000 description 3
• 230000020382 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Effects 0.000 description 3
• 239000004094 surface-active agent Substances 0.000 description 3
• 239000000725 suspension Substances 0.000 description 3
• 208000011317 telomere syndrome Diseases 0.000 description 3
• 238000012546 transfer Methods 0.000 description 3
• 230000032258 transport Effects 0.000 description 3
• YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
• KVGZZAHHUNAVKZ-UHFFFAOYSA-N 1,4-Dioxin Chemical compound O1C=COC=C1 KVGZZAHHUNAVKZ-UHFFFAOYSA-N 0.000 description 2
• HVAUUPRFYPCOCA-AREMUKBSSA-N 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCOC[C@@H](OC(C)=O)COP([O-])(=O)OCC[N+](C)(C)C HVAUUPRFYPCOCA-AREMUKBSSA-N 0.000 description 2
• 102100025425 2-oxoglutarate and iron-dependent oxygenase JMJD4 Human genes 0.000 description 2
• 101150033839 4 gene Proteins 0.000 description 2
• 102100031928 40S ribosomal protein S29 Human genes 0.000 description 2
• 101150096316 5 gene Proteins 0.000 description 2
• 102100035988 60S ribosomal protein L39 Human genes 0.000 description 2
• 102100032787 ATPase family AAA domain-containing protein 3A Human genes 0.000 description 2
• 108091006112 ATPases Proteins 0.000 description 2
• IKHGUXGNUITLKF-UHFFFAOYSA-N Acetaldehyde Chemical compound CC=O IKHGUXGNUITLKF-UHFFFAOYSA-N 0.000 description 2
• 102000057290 Adenosine Triphosphatases Human genes 0.000 description 2
• 102100036775 Afadin Human genes 0.000 description 2
• 101710186708 Agglutinin Proteins 0.000 description 2
• 102100036439 Amyloid beta precursor protein binding family B member 1 Human genes 0.000 description 2
• PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 description 2
• 102100033393 Anillin Human genes 0.000 description 2
• 102100034615 Ankyrin repeat domain-containing protein 10 Human genes 0.000 description 2
• 101710145634 Antigen 1 Proteins 0.000 description 2
• 108020000948 Antisense Oligonucleotides Proteins 0.000 description 2
• 101710081722 Antitrypsin Proteins 0.000 description 2
• 102100034605 Atrial natriuretic peptide receptor 3 Human genes 0.000 description 2
• 241000271566 Aves Species 0.000 description 2
• 102100027321 Beta-1,4-galactosyltransferase 7 Human genes 0.000 description 2
• 241000283690 Bos taurus Species 0.000 description 2
• 102100029893 Bromodomain-containing protein 9 Human genes 0.000 description 2
• 102100025250 C-X-C motif chemokine 14 Human genes 0.000 description 2
• OBMZMSLWNNWEJA-XNCRXQDQSA-N C1=CC=2C(C[C@@H]3NC(=O)[C@@H](NC(=O)[C@H](NC(=O)N(CC#CCN(CCCC[C@H](NC(=O)[C@@H](CC4=CC=CC=C4)NC3=O)C(=O)N)CC=C)NC(=O)[C@@H](N)C)CC3=CNC4=C3C=CC=C4)C)=CNC=2C=C1 Chemical compound C1=CC=2C(C[C@@H]3NC(=O)[C@@H](NC(=O)[C@H](NC(=O)N(CC#CCN(CCCC[C@H](NC(=O)[C@@H](CC4=CC=CC=C4)NC3=O)C(=O)N)CC=C)NC(=O)[C@@H](N)C)CC3=CNC4=C3C=CC=C4)C)=CNC=2C=C1 OBMZMSLWNNWEJA-XNCRXQDQSA-N 0.000 description 2
• OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
• 102000004663 Calcium-Calmodulin-Dependent Protein Kinase Type 1 Human genes 0.000 description 2
• 108010003764 Calcium-Calmodulin-Dependent Protein Kinase Type 1 Proteins 0.000 description 2
• 108010052500 Calgranulin A Proteins 0.000 description 2
• 241000282472 Canis lupus familiaris Species 0.000 description 2
• 102100026772 Cell cycle control protein 50A Human genes 0.000 description 2
• 102100038099 Cell division cycle protein 20 homolog Human genes 0.000 description 2
• 102100031219 Centrosomal protein of 55 kDa Human genes 0.000 description 2
• 206010008027 Cerebellar atrophy Diseases 0.000 description 2
• 108091006146 Channels Proteins 0.000 description 2
• 108010077544 Chromatin Proteins 0.000 description 2
• 102100031045 Coiled-coil domain-containing protein 14 Human genes 0.000 description 2
• 102100026766 Coiled-coil domain-containing protein 74B Human genes 0.000 description 2
• 108010047041 Complementarity Determining Regions Proteins 0.000 description 2
• 208000008448 Congenital adrenal hyperplasia Diseases 0.000 description 2
• 108091029523 CpG island Proteins 0.000 description 2
• 102100031565 Cytidine and dCMP deaminase domain-containing protein 1 Human genes 0.000 description 2
• SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 2
• 102100037985 Dickkopf-related protein 3 Human genes 0.000 description 2
• 101001031598 Dictyostelium discoideum Probable serine/threonine-protein kinase fhkC Proteins 0.000 description 2
• 102100034583 Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 1 Human genes 0.000 description 2
• 102100021160 Dual specificity protein phosphatase 9 Human genes 0.000 description 2
• 206010058314 Dysplasia Diseases 0.000 description 2
• 102100036448 Endothelial PAS domain-containing protein 1 Human genes 0.000 description 2
• 102100021579 Enhancer of filamentation 1 Human genes 0.000 description 2
• 241000283086 Equidae Species 0.000 description 2
• 102100038984 Exosome complex component RRP4 Human genes 0.000 description 2
• 108010014172 Factor V Proteins 0.000 description 2
• 241000282326 Felis catus Species 0.000 description 2
• 102100037362 Fibronectin Human genes 0.000 description 2
• 102100024520 Ficolin-3 Human genes 0.000 description 2
• 102100036963 Filamin A-interacting protein 1-like Human genes 0.000 description 2
• 102100037260 Gap junction beta-1 protein Human genes 0.000 description 2
• 102100037156 Gap junction beta-2 protein Human genes 0.000 description 2
• BPDVTFBJZNBHEU-HGNGGELXSA-N Glu-Ala-His Chemical compound OC(=O)CC[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@H](C(O)=O)CC1=CN=CN1 BPDVTFBJZNBHEU-HGNGGELXSA-N 0.000 description 2
• 108010000445 Glycerate dehydrogenase Proteins 0.000 description 2
• PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
• 102100039619 Granulocyte colony-stimulating factor Human genes 0.000 description 2
• 102000004144 Green Fluorescent Proteins Human genes 0.000 description 2
• 108010043121 Green Fluorescent Proteins Proteins 0.000 description 2
• ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 description 2
• 102100028972 HLA class I histocompatibility antigen, A alpha chain Human genes 0.000 description 2
• 108010013476 HLA-A24 Antigen Proteins 0.000 description 2
• 102100022057 Hepatocyte nuclear factor 1-alpha Human genes 0.000 description 2
• 102100038147 Histone chaperone ASF1B Human genes 0.000 description 2
• 108010033040 Histones Proteins 0.000 description 2
• 101000934666 Homo sapiens 2-oxoglutarate and iron-dependent oxygenase JMJD4 Proteins 0.000 description 2
• 101000923360 Homo sapiens ATPase family AAA domain-containing protein 3A Proteins 0.000 description 2
• 101000928246 Homo sapiens Afadin Proteins 0.000 description 2
• 101000928670 Homo sapiens Amyloid beta precursor protein binding family B member 1 Proteins 0.000 description 2
• 101000732632 Homo sapiens Anillin Proteins 0.000 description 2
• 101000924478 Homo sapiens Ankyrin repeat domain-containing protein 10 Proteins 0.000 description 2
• 101000924488 Homo sapiens Atrial natriuretic peptide receptor 3 Proteins 0.000 description 2
• 101000794032 Homo sapiens Bromodomain-containing protein 9 Proteins 0.000 description 2
• 101000858068 Homo sapiens C-X-C motif chemokine 14 Proteins 0.000 description 2
• 101000740685 Homo sapiens C4b-binding protein alpha chain Proteins 0.000 description 2
• 101000910814 Homo sapiens Cell cycle control protein 50A Proteins 0.000 description 2
• 101000776447 Homo sapiens Centrosomal protein of 55 kDa Proteins 0.000 description 2
• 101000777340 Homo sapiens Coiled-coil domain-containing protein 14 Proteins 0.000 description 2
• 101000910812 Homo sapiens Coiled-coil domain-containing protein 74B Proteins 0.000 description 2
• 101000777693 Homo sapiens Cytidine and dCMP deaminase domain-containing protein 1 Proteins 0.000 description 2
• 101000951342 Homo sapiens Dickkopf-related protein 3 Proteins 0.000 description 2
• 101000927648 Homo sapiens Dolichyldiphosphatase 1 Proteins 0.000 description 2
• 101000968556 Homo sapiens Dual specificity protein phosphatase 9 Proteins 0.000 description 2
• 101001052749 Homo sapiens Ficolin-3 Proteins 0.000 description 2
• 101000608772 Homo sapiens Galectin-7 Proteins 0.000 description 2
• 101000746367 Homo sapiens Granulocyte colony-stimulating factor Proteins 0.000 description 2
• 101000884473 Homo sapiens Histone chaperone ASF1B Proteins 0.000 description 2
• 101000935040 Homo sapiens Integrin beta-2 Proteins 0.000 description 2
• 101001008989 Homo sapiens KICSTOR subunit 2 Proteins 0.000 description 2
• 101000941071 Homo sapiens Lysosomal cobalamin transport escort protein LMBD1 Proteins 0.000 description 2
• 101000636206 Homo sapiens Matrix remodeling-associated protein 8 Proteins 0.000 description 2
• 101000582631 Homo sapiens Menin Proteins 0.000 description 2
• 101000669513 Homo sapiens Metalloproteinase inhibitor 1 Proteins 0.000 description 2
• 101000601616 Homo sapiens NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 Proteins 0.000 description 2
• 101001128634 Homo sapiens NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial Proteins 0.000 description 2
• 101000995204 Homo sapiens Neurabin-1 Proteins 0.000 description 2
• 101000582002 Homo sapiens Neuron navigator 2 Proteins 0.000 description 2
• 101000604027 Homo sapiens Nuclear protein localization protein 4 homolog Proteins 0.000 description 2
• 101001038567 Homo sapiens Nucleolar protein 4-like Proteins 0.000 description 2
• 101001109602 Homo sapiens Nucleolar protein 8 Proteins 0.000 description 2
• 101000598495 Homo sapiens Nucleoporin Nup37 Proteins 0.000 description 2
• 101000735223 Homo sapiens Palmdelphin Proteins 0.000 description 2
• 101001135199 Homo sapiens Partitioning defective 3 homolog Proteins 0.000 description 2
• 101000801640 Homo sapiens Phospholipid-transporting ATPase ABCA3 Proteins 0.000 description 2
• 101001049829 Homo sapiens Potassium channel subfamily K member 5 Proteins 0.000 description 2
• 101000901928 Homo sapiens Probable ATP-dependent RNA helicase DHX35 Proteins 0.000 description 2
• 101000728245 Homo sapiens Protein Aster-C Proteins 0.000 description 2
• 101000823451 Homo sapiens Protein FAM174C Proteins 0.000 description 2
• 101000768466 Homo sapiens Protein unc-13 homolog B Proteins 0.000 description 2
• 101001098557 Homo sapiens Proteinase-activated receptor 3 Proteins 0.000 description 2
• 101000591312 Homo sapiens Putative MORF4 family-associated protein 1-like protein UPP Proteins 0.000 description 2
• 101000822032 Homo sapiens Putative sodium-coupled neutral amino acid transporter 7 Proteins 0.000 description 2
• 101000626165 Homo sapiens Putative tenascin-XA Proteins 0.000 description 2
• 101000734537 Homo sapiens Pyridoxal-dependent decarboxylase domain-containing protein 1 Proteins 0.000 description 2
• 101000630197 Homo sapiens Rho GTPase-activating protein SYDE1 Proteins 0.000 description 2
• 101000886098 Homo sapiens Rho guanine nucleotide exchange factor 40 Proteins 0.000 description 2
• 101000752245 Homo sapiens Rho guanine nucleotide exchange factor 5 Proteins 0.000 description 2
• 101000588007 Homo sapiens SPARC-like protein 1 Proteins 0.000 description 2
• 101000706557 Homo sapiens SUN domain-containing protein 1 Proteins 0.000 description 2
• 101000661807 Homo sapiens Suppressor of tumorigenicity 14 protein Proteins 0.000 description 2
• 101001067250 Homo sapiens Transcription cofactor HES-6 Proteins 0.000 description 2
• 101000834926 Homo sapiens Transmembrane protein 106B Proteins 0.000 description 2
• 101000666063 Homo sapiens WD repeat-containing protein 74 Proteins 0.000 description 2
• 101000784545 Homo sapiens Zinc finger and SCAN domain-containing protein 18 Proteins 0.000 description 2
• 101000976608 Homo sapiens Zinc finger protein 408 Proteins 0.000 description 2
• 101001052394 Homo sapiens [F-actin]-monooxygenase MICAL1 Proteins 0.000 description 2
• 101710146024 Horcolin Proteins 0.000 description 2
• 102100027735 Hyaluronan mediated motility receptor Human genes 0.000 description 2
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 2
• 108010007666 IMP cyclohydrolase Proteins 0.000 description 2
• DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
• 102100020796 Inosine 5'-monophosphate cyclohydrolase Human genes 0.000 description 2
• 102000048143 Insulin-Like Growth Factor II Human genes 0.000 description 2
• 108090001117 Insulin-Like Growth Factor II Proteins 0.000 description 2
• 102100025390 Integrin beta-2 Human genes 0.000 description 2
• 102100021593 Interleukin-7 receptor subunit alpha Human genes 0.000 description 2
• 102100027622 KICSTOR subunit 2 Human genes 0.000 description 2
• 102100037691 Kinesin-like protein KIF20B Human genes 0.000 description 2
• AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 description 2
• GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
• 108010085895 Laminin Proteins 0.000 description 2
• 102000007547 Laminin Human genes 0.000 description 2
• 101710189395 Lectin Proteins 0.000 description 2
• 102000004856 Lectins Human genes 0.000 description 2
• 108090001090 Lectins Proteins 0.000 description 2
• 108090000364 Ligases Proteins 0.000 description 2
• 102100031335 Lysosomal cobalamin transport escort protein LMBD1 Human genes 0.000 description 2
• 208000002720 Malnutrition Diseases 0.000 description 2
• 101710179758 Mannose-specific lectin Proteins 0.000 description 2
• 101710150763 Mannose-specific lectin 1 Proteins 0.000 description 2
• 101710150745 Mannose-specific lectin 2 Proteins 0.000 description 2
• 102100030777 Matrix remodeling-associated protein 8 Human genes 0.000 description 2
• 102000000440 Melanoma-associated antigen Human genes 0.000 description 2
• 108050008953 Melanoma-associated antigen Proteins 0.000 description 2
• 206010027476 Metastases Diseases 0.000 description 2
• 102000002151 Microfilament Proteins Human genes 0.000 description 2
• 108010040897 Microfilament Proteins Proteins 0.000 description 2
• 102100026632 Mimecan Human genes 0.000 description 2
• 108010063954 Mucins Proteins 0.000 description 2
• 102000015728 Mucins Human genes 0.000 description 2
• 241000699666 Mus <mouse, genus> Species 0.000 description 2
• 241000699660 Mus musculus Species 0.000 description 2
• 108010083674 Myelin Proteins Proteins 0.000 description 2
• 102000006386 Myelin Proteins Human genes 0.000 description 2
• MBLBDJOUHNCFQT-UHFFFAOYSA-N N-acetyl-D-galactosamine Natural products CC(=O)NC(C=O)C(O)C(O)C(O)CO MBLBDJOUHNCFQT-UHFFFAOYSA-N 0.000 description 2
• 102100037508 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 Human genes 0.000 description 2
• 102100032194 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial Human genes 0.000 description 2
• 241000244206 Nematoda Species 0.000 description 2
• 102100024014 Nestin Human genes 0.000 description 2
• 102100034438 Neurabin-1 Human genes 0.000 description 2
• 102100030465 Neuron navigator 2 Human genes 0.000 description 2
• 102000005665 Neurotransmitter Transport Proteins Human genes 0.000 description 2
• 108010084810 Neurotransmitter Transport Proteins Proteins 0.000 description 2
• 102100038438 Nuclear protein localization protein 4 homolog Human genes 0.000 description 2
• 102100040313 Nucleolar protein 4-like Human genes 0.000 description 2
• 102100022740 Nucleolar protein 8 Human genes 0.000 description 2
• 102100022678 Nucleophosmin Human genes 0.000 description 2
• 108010025568 Nucleophosmin Proteins 0.000 description 2
• 102100037837 Nucleoporin Nup37 Human genes 0.000 description 2
• 102100023258 Nucleoside diphosphate kinase B Human genes 0.000 description 2
• 102000043276 Oncogene Human genes 0.000 description 2
• 108700026244 Open Reading Frames Proteins 0.000 description 2
• 102100035005 Palmdelphin Human genes 0.000 description 2
• 102100033496 Partitioning defective 3 homolog Human genes 0.000 description 2
• 101710176384 Peptide 1 Proteins 0.000 description 2
• 102100033623 Phospholipid-transporting ATPase ABCA3 Human genes 0.000 description 2
• 108010003541 Platelet Activating Factor Proteins 0.000 description 2
• 239000002202 Polyethylene glycol Substances 0.000 description 2
• 102100022424 Probable ATP-dependent RNA helicase DHX35 Human genes 0.000 description 2
• 102100020864 Prostaglandin F2 receptor negative regulator Human genes 0.000 description 2
• 239000004365 Protease Substances 0.000 description 2
• 102100029804 Protein Aster-C Human genes 0.000 description 2
• 102100022628 Protein FAM174C Human genes 0.000 description 2
• 102100029811 Protein S100-A11 Human genes 0.000 description 2
• 102100032442 Protein S100-A8 Human genes 0.000 description 2
• 102100027897 Protein unc-13 homolog B Human genes 0.000 description 2
• 102100034096 Putative MORF4 family-associated protein 1-like protein UPP Human genes 0.000 description 2
• 102100021471 Putative sodium-coupled neutral amino acid transporter 7 Human genes 0.000 description 2
• 102100024653 Putative tenascin-XA Human genes 0.000 description 2
• 102100034759 Pyridoxal-dependent decarboxylase domain-containing protein 1 Human genes 0.000 description 2
• LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 description 2
• 230000004570 RNA-binding Effects 0.000 description 2
• 102100027660 Rho GTPase-activating protein 15 Human genes 0.000 description 2
• 102100026203 Rho GTPase-activating protein SYDE1 Human genes 0.000 description 2
• 102100039653 Rho guanine nucleotide exchange factor 40 Human genes 0.000 description 2
• 102100021688 Rho guanine nucleotide exchange factor 5 Human genes 0.000 description 2
• 101710108887 Rhomboid-related protein 4 Proteins 0.000 description 2
• AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 2
• 102000002278 Ribosomal Proteins Human genes 0.000 description 2
• 108010000605 Ribosomal Proteins Proteins 0.000 description 2
• 108091006601 SLC16A3 Proteins 0.000 description 2
• 102100031581 SPARC-like protein 1 Human genes 0.000 description 2
• 102100031130 SUN domain-containing protein 1 Human genes 0.000 description 2
• 229920002684 Sepharose Polymers 0.000 description 2
• 102100029938 Serine/threonine-protein kinase SMG1 Human genes 0.000 description 2
• 102100023501 Signal peptide peptidase-like 3 Human genes 0.000 description 2
• FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 description 2
• 102100023153 Sodium- and chloride-dependent creatine transporter 1 Human genes 0.000 description 2
• 108091081024 Start codon Proteins 0.000 description 2
• 102100021685 Stomatin Human genes 0.000 description 2
• 102100032723 Structural maintenance of chromosomes protein 3 Human genes 0.000 description 2
• 108091008874 T cell receptors Proteins 0.000 description 2
• 102000016266 T-Cell Antigen Receptors Human genes 0.000 description 2
• MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 description 2
• 102000002932 Thiolase Human genes 0.000 description 2
• 108060008225 Thiolase Proteins 0.000 description 2
• 102100034424 Transcription cofactor HES-6 Human genes 0.000 description 2
• 102100026232 Transmembrane protein 106B Human genes 0.000 description 2
• 108060008683 Tumor Necrosis Factor Receptor Proteins 0.000 description 2
• 102100033178 Vascular endothelial growth factor receptor 1 Human genes 0.000 description 2
• 102100038091 WD repeat-containing protein 74 Human genes 0.000 description 2
• 101710087237 Whey acidic protein Proteins 0.000 description 2
• HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 2
• 102100020915 Zinc finger and SCAN domain-containing protein 18 Human genes 0.000 description 2
• 101710185494 Zinc finger protein Proteins 0.000 description 2
• 102100023597 Zinc finger protein 816 Human genes 0.000 description 2
• 102100023634 Zona pellucida sperm-binding protein 3 Human genes 0.000 description 2
• 102100024306 [F-actin]-monooxygenase MICAL1 Human genes 0.000 description 2
• 230000005856 abnormality Effects 0.000 description 2
• ZSLZBFCDCINBPY-ZSJPKINUSA-N acetyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 ZSLZBFCDCINBPY-ZSJPKINUSA-N 0.000 description 2
• 239000000910 agglutinin Substances 0.000 description 2
• FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 2
• 125000000539 amino acid group Chemical group 0.000 description 2
• 238000004458 analytical method Methods 0.000 description 2
• 230000033115 angiogenesis Effects 0.000 description 2
• 230000001475 anti-trypsic effect Effects 0.000 description 2
• 230000000890 antigenic effect Effects 0.000 description 2
• 125000003118 aryl group Chemical group 0.000 description 2
• 210000003719 b-lymphocyte Anatomy 0.000 description 2
• 230000008901 benefit Effects 0.000 description 2
• 210000004204 blood vessel Anatomy 0.000 description 2
• 239000000872 buffer Substances 0.000 description 2
• 229910052791 calcium Inorganic materials 0.000 description 2
• 238000004422 calculation algorithm Methods 0.000 description 2
• 239000002775 capsule Substances 0.000 description 2
• 230000022131 cell cycle Effects 0.000 description 2
• HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
• 210000003483 chromatin Anatomy 0.000 description 2
• RTIXKCRFFJGDFG-UHFFFAOYSA-N chrysin Chemical compound C=1C(O)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=CC=C1 RTIXKCRFFJGDFG-UHFFFAOYSA-N 0.000 description 2
• 238000003776 cleavage reaction Methods 0.000 description 2
• 238000004590 computer program Methods 0.000 description 2
• 238000007796 conventional method Methods 0.000 description 2
• 238000010168 coupling process Methods 0.000 description 2
• 238000005859 coupling reaction Methods 0.000 description 2
• CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 description 2
• 210000004748 cultured cell Anatomy 0.000 description 2
• 229940104302 cytosine Drugs 0.000 description 2
• 230000006378 damage Effects 0.000 description 2
• 238000013461 design Methods 0.000 description 2
• 239000001177 diphosphate Substances 0.000 description 2
• XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 description 2
• 235000011180 diphosphates Nutrition 0.000 description 2
• 230000009977 dual effect Effects 0.000 description 2
• 230000003028 elevating effect Effects 0.000 description 2
• 210000003743 erythrocyte Anatomy 0.000 description 2
• 230000000763 evoking effect Effects 0.000 description 2
• 230000002349 favourable effect Effects 0.000 description 2
• 238000011049 filling Methods 0.000 description 2
• 230000004992 fission Effects 0.000 description 2
• 230000002496 gastric effect Effects 0.000 description 2
• XGALLCVXEZPNRQ-UHFFFAOYSA-N gefitinib Chemical compound C=12C=C(OCCCN3CCOCC3)C(OC)=CC2=NC=NC=1NC1=CC=C(F)C(Cl)=C1 XGALLCVXEZPNRQ-UHFFFAOYSA-N 0.000 description 2
• 230000002068 genetic effect Effects 0.000 description 2
• 150000004676 glycans Chemical class 0.000 description 2
• 239000005090 green fluorescent protein Substances 0.000 description 2
• 230000002440 hepatic effect Effects 0.000 description 2
• 102000047681 human MEN1 Human genes 0.000 description 2
• 229920002674 hyaluronan Polymers 0.000 description 2
• 229910052739 hydrogen Inorganic materials 0.000 description 2
• 239000001257 hydrogen Substances 0.000 description 2
• WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 2
• 210000002865 immune cell Anatomy 0.000 description 2
• 210000000987 immune system Anatomy 0.000 description 2
• 230000003053 immunization Effects 0.000 description 2
• 230000001976 improved effect Effects 0.000 description 2
• 230000006698 induction Effects 0.000 description 2
• 238000003780 insertion Methods 0.000 description 2
• 230000037431 insertion Effects 0.000 description 2
• 238000007689 inspection Methods 0.000 description 2
• 102000006495 integrins Human genes 0.000 description 2
• 108010044426 integrins Proteins 0.000 description 2
• 230000003834 intracellular effect Effects 0.000 description 2
• AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 description 2
• 229960000310 isoleucine Drugs 0.000 description 2
• 238000002372 labelling Methods 0.000 description 2
• 239000008101 lactose Substances 0.000 description 2
• 239000002523 lectin Substances 0.000 description 2
• 239000007791 liquid phase Substances 0.000 description 2
• 210000004185 liver Anatomy 0.000 description 2
• 238000012423 maintenance Methods 0.000 description 2
• 230000003211 malignant effect Effects 0.000 description 2
• 230000001071 malnutrition Effects 0.000 description 2
• 235000000824 malnutrition Nutrition 0.000 description 2
• 230000007246 mechanism Effects 0.000 description 2
• 206010061289 metastatic neoplasm Diseases 0.000 description 2
• 238000002493 microarray Methods 0.000 description 2
• 235000013336 milk Nutrition 0.000 description 2
• 210000004080 milk Anatomy 0.000 description 2
• 239000008267 milk Substances 0.000 description 2
• 230000002438 mitochondrial effect Effects 0.000 description 2
• 238000002156 mixing Methods 0.000 description 2
• 238000010369 molecular cloning Methods 0.000 description 2
• 210000005012 myelin Anatomy 0.000 description 2
• 108010076457 nonmuscle myosin type IIB heavy chain Proteins 0.000 description 2
• 208000015380 nutritional deficiency disease Diseases 0.000 description 2
• 210000000056 organ Anatomy 0.000 description 2
• 230000008520 organization Effects 0.000 description 2
• 210000000496 pancreas Anatomy 0.000 description 2
• 230000037361 pathway Effects 0.000 description 2
• 229910052698 phosphorus Inorganic materials 0.000 description 2
• 229920002401 polyacrylamide Polymers 0.000 description 2
• 229920001223 polyethylene glycol Polymers 0.000 description 2
• 229920001282 polysaccharide Polymers 0.000 description 2
• 239000005017 polysaccharide Substances 0.000 description 2
• 230000002062 proliferating effect Effects 0.000 description 2
• 230000035755 proliferation Effects 0.000 description 2
• 230000001737 promoting effect Effects 0.000 description 2
• 235000019419 proteases Nutrition 0.000 description 2
• 108010078587 pseudouridylate synthetase Proteins 0.000 description 2
• 238000005215 recombination Methods 0.000 description 2
• 230000004044 response Effects 0.000 description 2
• 102000025704 ribonucleotide binding proteins Human genes 0.000 description 2
• 108091014734 ribonucleotide binding proteins Proteins 0.000 description 2
• 210000003491 skin Anatomy 0.000 description 2
• 150000003384 small molecules Chemical class 0.000 description 2
• 239000011734 sodium Substances 0.000 description 2
• 229910052708 sodium Inorganic materials 0.000 description 2
• 229910001415 sodium ion Inorganic materials 0.000 description 2
• PFNFFQXMRSDOHW-UHFFFAOYSA-N spermine Chemical compound NCCCNCCCCNCCCN PFNFFQXMRSDOHW-UHFFFAOYSA-N 0.000 description 2
• 108010088201 squamous cell carcinoma-related antigen Proteins 0.000 description 2
• 239000003381 stabilizer Substances 0.000 description 2
• 150000003431 steroids Chemical class 0.000 description 2
• 230000000638 stimulation Effects 0.000 description 2
• 229910052717 sulfur Inorganic materials 0.000 description 2
• 102100029783 tRNA pseudouridine synthase A Human genes 0.000 description 2
• 210000001550 testis Anatomy 0.000 description 2
• 229940124597 therapeutic agent Drugs 0.000 description 2
• 229940126585 therapeutic drug Drugs 0.000 description 2
• 238000002560 therapeutic procedure Methods 0.000 description 2
• 210000002105 tongue Anatomy 0.000 description 2
• 239000003053 toxin Substances 0.000 description 2
• 231100000765 toxin Toxicity 0.000 description 2
• 238000010361 transduction Methods 0.000 description 2
• 230000026683 transduction Effects 0.000 description 2
• 238000013519 translation Methods 0.000 description 2
• 230000014621 translational initiation Effects 0.000 description 2
• 230000005945 translocation Effects 0.000 description 2
• 102000035160 transmembrane proteins Human genes 0.000 description 2
• 108091005703 transmembrane proteins Proteins 0.000 description 2
• 239000002753 trypsin inhibitor Substances 0.000 description 2
• 102000003298 tumor necrosis factor receptor Human genes 0.000 description 2
• 238000007039 two-step reaction Methods 0.000 description 2
• DZGWFCGJZKJUFP-UHFFFAOYSA-N tyramine Chemical compound NCCC1=CC=C(O)C=C1 DZGWFCGJZKJUFP-UHFFFAOYSA-N 0.000 description 2
• 229940121358 tyrosine kinase inhibitor Drugs 0.000 description 2
• 239000005483 tyrosine kinase inhibitor Substances 0.000 description 2
• 210000002700 urine Anatomy 0.000 description 2
• 230000002792 vascular Effects 0.000 description 2
• 210000004885 white matter Anatomy 0.000 description 2
• 210000005253 yeast cell Anatomy 0.000 description 2
• 229910052725 zinc Inorganic materials 0.000 description 2
• 239000011701 zinc Substances 0.000 description 2
• WWUZIQQURGPMPG-UHFFFAOYSA-N (-)-D-erythro-Sphingosine Natural products CCCCCCCCCCCCCC=CC(O)C(N)CO WWUZIQQURGPMPG-UHFFFAOYSA-N 0.000 description 1
• KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
• NPOCDVAOUKODSQ-ZDUSSCGKSA-N (2s)-2-amino-6-[6-(2-methoxyethoxy)hexanoylamino]hexanoic acid Chemical compound COCCOCCCCCC(=O)NCCCC[C@H](N)C(O)=O NPOCDVAOUKODSQ-ZDUSSCGKSA-N 0.000 description 1
• IXRAQYMAEVFORF-UTLNTRLCSA-N (3S,8S,9S,10R,13S,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,16-diol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC(O)[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 IXRAQYMAEVFORF-UTLNTRLCSA-N 0.000 description 1
• HVYWMOMLDIMFJA-VEIPTCAHSA-N (3r,8s,9s,10r,13r,14s,17r)-10,13-dimethyl-17-[(2r)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-ol Chemical compound C1C=C2C[C@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-VEIPTCAHSA-N 0.000 description 1
• FQVLRGLGWNWPSS-BXBUPLCLSA-N (4r,7s,10s,13s,16r)-16-acetamido-13-(1h-imidazol-5-ylmethyl)-10-methyl-6,9,12,15-tetraoxo-7-propan-2-yl-1,2-dithia-5,8,11,14-tetrazacycloheptadecane-4-carboxamide Chemical compound N1C(=O)[C@@H](NC(C)=O)CSSC[C@@H](C(N)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@@H]1CC1=CN=CN1 FQVLRGLGWNWPSS-BXBUPLCLSA-N 0.000 description 1
• KJTLQQUUPVSXIM-ZCFIWIBFSA-M (R)-mevalonate Chemical compound OCC[C@](O)(C)CC([O-])=O KJTLQQUUPVSXIM-ZCFIWIBFSA-M 0.000 description 1
• SSAYTINUCCRGDR-OWOJBTEDSA-N (e)-3-pyridin-4-ylprop-2-enoic acid Chemical compound OC(=O)\C=C\C1=CC=NC=C1 SSAYTINUCCRGDR-OWOJBTEDSA-N 0.000 description 1
• NILQLFBWTXNUOE-UHFFFAOYSA-N 1-aminocyclopentanecarboxylic acid Chemical compound OC(=O)C1(N)CCCC1 NILQLFBWTXNUOE-UHFFFAOYSA-N 0.000 description 1
• GZCWLCBFPRFLKL-UHFFFAOYSA-N 1-prop-2-ynoxypropan-2-ol Chemical compound CC(O)COCC#C GZCWLCBFPRFLKL-UHFFFAOYSA-N 0.000 description 1
• OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
• 102100036506 11-beta-hydroxysteroid dehydrogenase 1 Human genes 0.000 description 1
• 102100031236 11-beta-hydroxysteroid dehydrogenase type 2 Human genes 0.000 description 1
• FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
• 102100027833 14-3-3 protein sigma Human genes 0.000 description 1
• 108050008974 14-3-3 protein sigma Proteins 0.000 description 1
• 102100030489 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Human genes 0.000 description 1
• 102100038794 17-beta-hydroxysteroid dehydrogenase type 6 Human genes 0.000 description 1
• BFSVOASYOCHEOV-UHFFFAOYSA-N 2-diethylaminoethanol Chemical compound CCN(CC)CCO BFSVOASYOCHEOV-UHFFFAOYSA-N 0.000 description 1
• 101710197207 2-iminoacetate synthase Proteins 0.000 description 1
• 102100034682 26S proteasome regulatory subunit 7 Human genes 0.000 description 1
• MSYGAHOHLUJIKV-UHFFFAOYSA-N 3,5-dimethyl-1-(3-nitrophenyl)-1h-pyrazole-4-carboxylic acid ethyl ester Chemical compound CC1=C(C(=O)OCC)C(C)=NN1C1=CC=CC([N+]([O-])=O)=C1 MSYGAHOHLUJIKV-UHFFFAOYSA-N 0.000 description 1
• AMQVHASIFJZFOS-UHFFFAOYSA-N 3-[(4-chlorophenyl)-(4-hydroxy-2-oxochromen-3-yl)methyl]-4-hydroxychromen-2-one Chemical compound O=C1OC=2C=CC=CC=2C(O)=C1C(C=1C(OC2=CC=CC=C2C=1O)=O)C1=CC=C(Cl)C=C1 AMQVHASIFJZFOS-UHFFFAOYSA-N 0.000 description 1
• 102100034767 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Human genes 0.000 description 1
• 102100026105 3-ketoacyl-CoA thiolase, mitochondrial Human genes 0.000 description 1
• 102100034254 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Human genes 0.000 description 1
• 102100026163 39S ribosomal protein L12, mitochondrial Human genes 0.000 description 1
• 102100022031 39S ribosomal protein L23, mitochondrial Human genes 0.000 description 1
• 101710198769 40S ribosomal protein S15a Proteins 0.000 description 1
• 102100037710 40S ribosomal protein S21 Human genes 0.000 description 1
• 102100033449 40S ribosomal protein S24 Human genes 0.000 description 1
• 102100027271 40S ribosomal protein SA Human genes 0.000 description 1
• QCVGEOXPDFCNHA-UHFFFAOYSA-N 5,5-dimethyl-2,4-dioxo-1,3-oxazolidine-3-carboxamide Chemical compound CC1(C)OC(=O)N(C(N)=O)C1=O QCVGEOXPDFCNHA-UHFFFAOYSA-N 0.000 description 1
• NYCXYKOXLNBYID-UHFFFAOYSA-N 5,7-Dihydroxychromone Natural products O1C=CC(=O)C=2C1=CC(O)=CC=2O NYCXYKOXLNBYID-UHFFFAOYSA-N 0.000 description 1
• SUCPTJIDWIPYDE-UHFFFAOYSA-N 5-(2,2-dimethylpropyl)nonan-5-ol Chemical compound CCCCC(O)(CC(C)(C)C)CCCC SUCPTJIDWIPYDE-UHFFFAOYSA-N 0.000 description 1
• DVNYTAVYBRSTGK-UHFFFAOYSA-N 5-aminoimidazole-4-carboxamide Chemical class NC(=O)C=1N=CNC=1N DVNYTAVYBRSTGK-UHFFFAOYSA-N 0.000 description 1
• 102100021324 5-azacytidine-induced protein 2 Human genes 0.000 description 1
• SUEOMVYNPBJIDY-UHFFFAOYSA-N 5-methyl-4-oxo-1h-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid Chemical compound N1=CN=C(O)C2=C(C)C(C(O)=O)=CN21 SUEOMVYNPBJIDY-UHFFFAOYSA-N 0.000 description 1
• 102100026112 60S acidic ribosomal protein P2 Human genes 0.000 description 1
• 102100021690 60S ribosomal protein L18a Human genes 0.000 description 1
• 102100021927 60S ribosomal protein L27a Human genes 0.000 description 1
• 102100040540 60S ribosomal protein L3 Human genes 0.000 description 1
• 101710117444 60S ribosomal protein L3 Proteins 0.000 description 1
• 102100022048 60S ribosomal protein L36 Human genes 0.000 description 1
• 101710187872 60S ribosomal protein L36 Proteins 0.000 description 1
• 102100027398 A disintegrin and metalloproteinase with thrombospondin motifs 1 Human genes 0.000 description 1
• 102100033824 A-kinase anchor protein 12 Human genes 0.000 description 1
• 102100031901 A-kinase anchor protein 2 Human genes 0.000 description 1
• 108091005660 ADAMTS1 Proteins 0.000 description 1
• 102100022861 ADP-ribosylation factor-like protein 5A Human genes 0.000 description 1
• 102100024379 AF4/FMR2 family member 1 Human genes 0.000 description 1
• 102100034531 AP-1 complex subunit mu-2 Human genes 0.000 description 1
• 102100028780 AP-1 complex subunit sigma-2 Human genes 0.000 description 1
• 102100034481 AP-1 complex-associated regulatory protein Human genes 0.000 description 1
• 102100033347 AP-2 complex subunit beta Human genes 0.000 description 1
• 108091008803 APLNR Proteins 0.000 description 1
• 102100023568 ATP synthase F(0) complex subunit C1, mitochondrial Human genes 0.000 description 1
• 102100027573 ATP synthase subunit alpha, mitochondrial Human genes 0.000 description 1
• 102100023388 ATP-dependent RNA helicase DHX15 Human genes 0.000 description 1
• 102100024825 ATPase MORC2 Human genes 0.000 description 1
• QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
• 108010051457 Acid Phosphatase Proteins 0.000 description 1
• 102000013563 Acid Phosphatase Human genes 0.000 description 1
• 102100024005 Acid ceramidase Human genes 0.000 description 1
• 102100036732 Actin, aortic smooth muscle Human genes 0.000 description 1
• 101710197633 Actin-1 Proteins 0.000 description 1
• 102100020961 Actin-binding LIM protein 3 Human genes 0.000 description 1
• 102100033888 Actin-related protein 2/3 complex subunit 4 Human genes 0.000 description 1
• 241000251468 Actinopterygii Species 0.000 description 1
• 108010059616 Activins Proteins 0.000 description 1
• 208000010507 Adenocarcinoma of Lung Diseases 0.000 description 1
• 102100035990 Adenosine receptor A2a Human genes 0.000 description 1
• 206010068873 Adenosquamous cell carcinoma Diseases 0.000 description 1
• 102100020925 Adenosylhomocysteinase Human genes 0.000 description 1
• 102100031933 Adhesion G protein-coupled receptor F5 Human genes 0.000 description 1
• 102100036791 Adhesion G protein-coupled receptor L2 Human genes 0.000 description 1
• 102100024394 Adipocyte enhancer-binding protein 1 Human genes 0.000 description 1
• 206010067484 Adverse reaction Diseases 0.000 description 1
• 102100036457 Akirin-1 Human genes 0.000 description 1
• 102100034035 Alcohol dehydrogenase 1A Human genes 0.000 description 1
• 102100034042 Alcohol dehydrogenase 1C Human genes 0.000 description 1
• 101710187571 Alcohol dehydrogenase 3 Proteins 0.000 description 1
• 102100040069 Aldehyde dehydrogenase 1A1 Human genes 0.000 description 1
• 102100026605 Aldehyde dehydrogenase, dimeric NADP-preferring Human genes 0.000 description 1
• 101710150756 Aldehyde dehydrogenase, mitochondrial Proteins 0.000 description 1
• 108010053754 Aldehyde reductase Proteins 0.000 description 1
• 102000003677 Aldehyde-Lyases Human genes 0.000 description 1
• 108090000072 Aldehyde-Lyases Proteins 0.000 description 1
• 102100027265 Aldo-keto reductase family 1 member B1 Human genes 0.000 description 1
• 102100026451 Aldo-keto reductase family 1 member B10 Human genes 0.000 description 1
• 102100024090 Aldo-keto reductase family 1 member C3 Human genes 0.000 description 1
• 101710117290 Aldo-keto reductase family 1 member C4 Proteins 0.000 description 1
• 102100034044 All-trans-retinol dehydrogenase [NAD(+)] ADH1B Human genes 0.000 description 1
• 101710193111 All-trans-retinol dehydrogenase [NAD(+)] ADH4 Proteins 0.000 description 1
• 102000040717 Alpha family Human genes 0.000 description 1
• 108091071248 Alpha family Proteins 0.000 description 1
• 102100022712 Alpha-1-antitrypsin Human genes 0.000 description 1
• 102100033879 Alpha-amylase 1A Human genes 0.000 description 1
• 102100040743 Alpha-crystallin B chain Human genes 0.000 description 1
• 102100021763 Alpha-mannosidase 2x Human genes 0.000 description 1
• 244000144730 Amygdalus persica Species 0.000 description 1
• 102100040038 Amyloid beta precursor like protein 2 Human genes 0.000 description 1
• 102100022704 Amyloid-beta precursor protein Human genes 0.000 description 1
• 101710151993 Amyloid-beta precursor protein Proteins 0.000 description 1
• 102100022987 Angiogenin Human genes 0.000 description 1
• 102100034594 Angiopoietin-1 Human genes 0.000 description 1
• 102100025672 Angiopoietin-related protein 2 Human genes 0.000 description 1
• 108090001067 Angiotensinogen Proteins 0.000 description 1
• 102000004881 Angiotensinogen Human genes 0.000 description 1
• 102100027139 Ankyrin repeat and SAM domain-containing protein 1A Human genes 0.000 description 1
• 102100040006 Annexin A1 Human genes 0.000 description 1
• 102100034283 Annexin A5 Human genes 0.000 description 1
• 102100034278 Annexin A6 Human genes 0.000 description 1
• 102100031936 Anterior gradient protein 2 homolog Human genes 0.000 description 1
• 102100030343 Antigen peptide transporter 2 Human genes 0.000 description 1
• 108050001544 Antigen peptide transporter 2 Proteins 0.000 description 1
• 102100030949 Apelin receptor Human genes 0.000 description 1
• 102100022954 Apolipoprotein D Human genes 0.000 description 1
• 102100021569 Apoptosis regulator Bcl-2 Human genes 0.000 description 1
• 102000012002 Aquaporin 4 Human genes 0.000 description 1
• 108010036280 Aquaporin 4 Proteins 0.000 description 1
• 101100107608 Arabidopsis thaliana ABCC4 gene Proteins 0.000 description 1
• 101000693933 Arabidopsis thaliana Fructose-bisphosphate aldolase 8, cytosolic Proteins 0.000 description 1
• 101000895097 Arabidopsis thaliana Histone-lysine N-methyltransferase ATX4 Proteins 0.000 description 1
• 102100024003 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 Human genes 0.000 description 1
• 208000002109 Argyria Diseases 0.000 description 1
• 241000796533 Arna Species 0.000 description 1
• 102100029361 Aromatase Human genes 0.000 description 1
• 108010078554 Aromatase Proteins 0.000 description 1
• 102100026424 Arrestin domain-containing protein 3 Human genes 0.000 description 1
• 102100039339 Atrial natriuretic peptide receptor 1 Human genes 0.000 description 1
• 102100035553 Autism susceptibility gene 2 protein Human genes 0.000 description 1
• 108090001008 Avidin Proteins 0.000 description 1
• 102100035682 Axin-1 Human genes 0.000 description 1
• 102100028046 BAG family molecular chaperone regulator 5 Human genes 0.000 description 1
• 108091012583 BCL2 Proteins 0.000 description 1
• 102100035080 BDNF/NT-3 growth factors receptor Human genes 0.000 description 1
• 108091007065 BIRCs Proteins 0.000 description 1
• 241000894006 Bacteria Species 0.000 description 1
• 102100021663 Baculoviral IAP repeat-containing protein 5 Human genes 0.000 description 1
• 102100023046 Band 4.1-like protein 3 Human genes 0.000 description 1
• 102100032423 Bcl-2-associated transcription factor 1 Human genes 0.000 description 1
• 102100039848 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 Human genes 0.000 description 1
• 102100026044 Biotinidase Human genes 0.000 description 1
• 241000255789 Bombyx mori Species 0.000 description 1
• 102100022525 Bone morphogenetic protein 6 Human genes 0.000 description 1
• 101000645291 Bos taurus Metalloproteinase inhibitor 2 Proteins 0.000 description 1
• WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 1
• 102100021743 Bromodomain and PHD finger-containing protein 3 Human genes 0.000 description 1
• 102100021714 Bystin Human genes 0.000 description 1
• 102100031172 C-C chemokine receptor type 1 Human genes 0.000 description 1
• 101710149814 C-C chemokine receptor type 1 Proteins 0.000 description 1
• 102100031102 C-C motif chemokine 4 Human genes 0.000 description 1
• 102100025248 C-X-C motif chemokine 10 Human genes 0.000 description 1
• 102100026194 C-type lectin domain family 2 member B Human genes 0.000 description 1
• 102100025351 C-type mannose receptor 2 Human genes 0.000 description 1
• SMHKSONAHYPWPN-VSGGKJORSA-N C1(=CC=CC=2C3=CC=CC=C3CC12)N[C@@H](CO)[C@H](O)\C=C\CCCCCCCCCCCCC Chemical compound C1(=CC=CC=2C3=CC=CC=C3CC12)N[C@@H](CO)[C@H](O)\C=C\CCCCCCCCCCCCC SMHKSONAHYPWPN-VSGGKJORSA-N 0.000 description 1
• 102100037084 C4b-binding protein alpha chain Human genes 0.000 description 1
• 102100033611 CB1 cannabinoid receptor-interacting protein 1 Human genes 0.000 description 1
• 108010032389 CBFA2T2 myeloid-transforming gene-related protein Proteins 0.000 description 1
• 108010026988 CCAAT-Binding Factor Proteins 0.000 description 1
• 102100037676 CCAAT/enhancer-binding protein zeta Human genes 0.000 description 1
• 102100032982 CCR4-NOT transcription complex subunit 9 Human genes 0.000 description 1
• 102100035793 CD83 antigen Human genes 0.000 description 1
• 108700020472 CDC20 Proteins 0.000 description 1
• 102100031198 CGG triplet repeat-binding protein 1 Human genes 0.000 description 1
• 102100022620 COMM domain-containing protein 5 Human genes 0.000 description 1
• 102100028228 COUP transcription factor 1 Human genes 0.000 description 1
• 102100028226 COUP transcription factor 2 Human genes 0.000 description 1
• 108091011896 CSF1 Proteins 0.000 description 1
• 102100027674 CTD small phosphatase-like protein Human genes 0.000 description 1
• 101150099461 CTL2 gene Proteins 0.000 description 1
• 102000000905 Cadherin Human genes 0.000 description 1
• 108050007957 Cadherin Proteins 0.000 description 1
• 102100024154 Cadherin-13 Human genes 0.000 description 1
• 102100024153 Cadherin-15 Human genes 0.000 description 1
• 102100029761 Cadherin-5 Human genes 0.000 description 1
• 101100456610 Caenorhabditis elegans mdt-6 gene Proteins 0.000 description 1
• 102100027557 Calcipressin-1 Human genes 0.000 description 1
• 102100029171 Calcipressin-2 Human genes 0.000 description 1
• 108060001064 Calcitonin Proteins 0.000 description 1
• 102000055006 Calcitonin Human genes 0.000 description 1
• 102100033349 Calcium homeostasis endoplasmic reticulum protein Human genes 0.000 description 1
• 102000005701 Calcium-Binding Proteins Human genes 0.000 description 1
• 108010045403 Calcium-Binding Proteins Proteins 0.000 description 1
• 102100036362 Calcium-binding and coiled-coil domain-containing protein 1 Human genes 0.000 description 1
• 102100025338 Calcium-binding tyrosine phosphorylation-regulated protein Human genes 0.000 description 1
• 101710155556 Calcium-dependent protease Proteins 0.000 description 1
• 102100035632 Calcyphosin Human genes 0.000 description 1
• 101710085913 Calcyphosin Proteins 0.000 description 1
• 102100024436 Caldesmon Human genes 0.000 description 1
• 102100033561 Calmodulin-binding transcription activator 1 Human genes 0.000 description 1
• 102100029383 Calpain small subunit 2 Human genes 0.000 description 1
• 102100033620 Calponin-1 Human genes 0.000 description 1
• 102100025570 Cancer/testis antigen 1 Human genes 0.000 description 1
• 101001024441 Candida albicans (strain SC5314 / ATCC MYA-2876) Major facilitator superfamily multidrug transporter NAG3 Proteins 0.000 description 1
• 244000025254 Cannabis sativa Species 0.000 description 1
• 235000012766 Cannabis sativa ssp. sativa var. sativa Nutrition 0.000 description 1
• 235000012765 Cannabis sativa ssp. sativa var. spontanea Nutrition 0.000 description 1
• 101710132601 Capsid protein Proteins 0.000 description 1
• UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 description 1
• 102100033040 Carbonic anhydrase 12 Human genes 0.000 description 1
• 102000003846 Carbonic anhydrases Human genes 0.000 description 1
• 108090000209 Carbonic anhydrases Proteins 0.000 description 1
• 201000009030 Carcinoma Diseases 0.000 description 1
• 102100040751 Casein kinase II subunit alpha Human genes 0.000 description 1
• 102100024974 Caspase recruitment domain-containing protein 8 Human genes 0.000 description 1
• 102100025953 Cathepsin F Human genes 0.000 description 1
• 102100026540 Cathepsin L2 Human genes 0.000 description 1
• 102100035654 Cathepsin S Human genes 0.000 description 1
• 102100038909 Caveolin-2 Human genes 0.000 description 1
• 241000700198 Cavia Species 0.000 description 1
• 101150023302 Cdc20 gene Proteins 0.000 description 1
• 102000011068 Cdc42 Human genes 0.000 description 1
• 108050001278 Cdc42 Proteins 0.000 description 1
• 102100032346 Cell cycle progression protein 1 Human genes 0.000 description 1
• 102100038503 Cellular retinoic acid-binding protein 1 Human genes 0.000 description 1
• 102100038504 Cellular retinoic acid-binding protein 2 Human genes 0.000 description 1
• 241000282693 Cercopithecidae Species 0.000 description 1
• 206010008479 Chest Pain Diseases 0.000 description 1
• 108010083195 Chlordecone reductase Proteins 0.000 description 1
• 102100023508 Chloride intracellular channel protein 4 Human genes 0.000 description 1
• 102000009016 Cholera Toxin Human genes 0.000 description 1
• 108010049048 Cholera Toxin Proteins 0.000 description 1
• 102100035954 Choline transporter-like protein 2 Human genes 0.000 description 1
• 229920002567 Chondroitin Polymers 0.000 description 1
• 102100037327 Chondrolectin Human genes 0.000 description 1
• 208000010126 Chondromatosis Diseases 0.000 description 1
• 102100038602 Chromatin assembly factor 1 subunit A Human genes 0.000 description 1
• 102100040836 Claudin-1 Human genes 0.000 description 1
• 102100038445 Claudin-2 Human genes 0.000 description 1
• 102100038446 Claudin-5 Human genes 0.000 description 1
• 102100029057 Coagulation factor XIII A chain Human genes 0.000 description 1
• 102000005870 Coenzyme A Ligases Human genes 0.000 description 1
• 102100034963 Coiled-coil domain-containing protein 167 Human genes 0.000 description 1
• 102100030501 Coiled-coil domain-containing protein 180 Human genes 0.000 description 1
• 102100026782 Coiled-coil domain-containing protein 85A Human genes 0.000 description 1
• 102000000503 Collagen Type II Human genes 0.000 description 1
• 108010041390 Collagen Type II Proteins 0.000 description 1
• 102100031611 Collagen alpha-1(III) chain Human genes 0.000 description 1
• 102100022145 Collagen alpha-1(IV) chain Human genes 0.000 description 1
• 102100024335 Collagen alpha-1(VII) chain Human genes 0.000 description 1
• 102100036213 Collagen alpha-2(I) chain Human genes 0.000 description 1
• 102100031518 Collagen alpha-2(VI) chain Human genes 0.000 description 1
• 108060005980 Collagenase Proteins 0.000 description 1
• 102000029816 Collagenase Human genes 0.000 description 1
• 229940122097 Collagenase inhibitor Drugs 0.000 description 1
• 102100024330 Collectin-12 Human genes 0.000 description 1
• 206010009944 Colon cancer Diseases 0.000 description 1
• 208000001333 Colorectal Neoplasms Diseases 0.000 description 1
• 108010028774 Complement C1 Proteins 0.000 description 1
• 102000016917 Complement C1 Human genes 0.000 description 1
• 108010078043 Complement C1q Proteins 0.000 description 1
• 102000014447 Complement C1q Human genes 0.000 description 1
• 102100030135 Complement C1q tumor necrosis factor-related protein 5 Human genes 0.000 description 1
• 108090000955 Complement C2 Proteins 0.000 description 1
• 102000004381 Complement C2 Human genes 0.000 description 1
• 102100033772 Complement C4-A Human genes 0.000 description 1
• 108010077773 Complement C4a Proteins 0.000 description 1
• 206010010356 Congenital anomaly Diseases 0.000 description 1
• 102000010970 Connexin Human genes 0.000 description 1
• 108050001175 Connexin Proteins 0.000 description 1
• 108010069156 Connexin 26 Proteins 0.000 description 1
• 206010010774 Constipation Diseases 0.000 description 1
• 108091004554 Copper Transport Proteins Proteins 0.000 description 1
• 102000037773 Copper transporters Human genes 0.000 description 1
• 108091006566 Copper transporters Proteins 0.000 description 1
• 108010072732 Core Binding Factors Proteins 0.000 description 1
• 102000006990 Core Binding Factors Human genes 0.000 description 1
• 102100031673 Corneodesmosin Human genes 0.000 description 1
• 101710139375 Corneodesmosin Proteins 0.000 description 1
• 101710156796 Cornifin Proteins 0.000 description 1
• 102100030291 Cornifin-B Human genes 0.000 description 1
• 101000796894 Coturnix japonica Alcohol dehydrogenase 1 Proteins 0.000 description 1
• 235000019750 Crude protein Nutrition 0.000 description 1
• 244000241257 Cucumis melo Species 0.000 description 1
• 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
• 101710095468 Cyclase Proteins 0.000 description 1
• 102100023578 Cyclic AMP-dependent transcription factor ATF-7 Human genes 0.000 description 1
• 101710093674 Cyclic nucleotide-gated cation channel beta-1 Proteins 0.000 description 1
• 108010024986 Cyclin-Dependent Kinase 2 Proteins 0.000 description 1
• 102100033245 Cyclin-dependent kinase 16 Human genes 0.000 description 1
• 102100036239 Cyclin-dependent kinase 2 Human genes 0.000 description 1
• 102100034770 Cyclin-dependent kinase inhibitor 3 Human genes 0.000 description 1
• 102100034501 Cyclin-dependent kinases regulatory subunit 1 Human genes 0.000 description 1
• 102100031237 Cystatin-A Human genes 0.000 description 1
• 108010005843 Cysteine Proteases Proteins 0.000 description 1
• 102000005927 Cysteine Proteases Human genes 0.000 description 1
• 102100031051 Cysteine and glycine-rich protein 1 Human genes 0.000 description 1
• 102000005889 Cysteine-Rich Protein 61 Human genes 0.000 description 1
• 108010019961 Cysteine-Rich Protein 61 Proteins 0.000 description 1
• 102100031127 Cysteine/serine-rich nuclear protein 1 Human genes 0.000 description 1
• 108010074918 Cytochrome P-450 CYP1A1 Proteins 0.000 description 1
• 108010081668 Cytochrome P-450 CYP3A Proteins 0.000 description 1
• 102100031476 Cytochrome P450 1A1 Human genes 0.000 description 1
• 102100027417 Cytochrome P450 1B1 Human genes 0.000 description 1
• 102100039208 Cytochrome P450 3A5 Human genes 0.000 description 1
• 102100025287 Cytochrome b Human genes 0.000 description 1
• 102100039924 Cytochrome b-c1 complex subunit 1, mitochondrial Human genes 0.000 description 1
• 101800000778 Cytochrome b-c1 complex subunit 9 Proteins 0.000 description 1
• 102400000011 Cytochrome b-c1 complex subunit 9 Human genes 0.000 description 1
• 102100031655 Cytochrome b5 Human genes 0.000 description 1
• 102100030497 Cytochrome c Human genes 0.000 description 1
• 102100036035 Cytochrome c oxidase copper chaperone Human genes 0.000 description 1
• 102100031649 Cytochrome c oxidase subunit 6B1 Human genes 0.000 description 1
• 102100028202 Cytochrome c oxidase subunit 6C Human genes 0.000 description 1
• 102000000634 Cytochrome c oxidase subunit IV Human genes 0.000 description 1
• 108090000365 Cytochrome-c oxidases Proteins 0.000 description 1
• 108010075028 Cytochromes b Proteins 0.000 description 1
• 108010075031 Cytochromes c Proteins 0.000 description 1
• 102100028183 Cytohesin-interacting protein Human genes 0.000 description 1
• 102100039061 Cytokine receptor common subunit beta Human genes 0.000 description 1
• 102100021999 Cytosolic Fe-S cluster assembly factor NUBP2 Human genes 0.000 description 1
• 102100035027 Cytosolic carboxypeptidase 1 Human genes 0.000 description 1
• 102100035149 Cytosolic endo-beta-N-acetylglucosaminidase Human genes 0.000 description 1
• 102100037579 D-3-phosphoglycerate dehydrogenase Human genes 0.000 description 1
• WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 1
• 102100029816 DEP domain-containing mTOR-interacting protein Human genes 0.000 description 1
• KJTLQQUUPVSXIM-UHFFFAOYSA-N DL-mevalonic acid Natural products OCCC(O)(C)CC(O)=O KJTLQQUUPVSXIM-UHFFFAOYSA-N 0.000 description 1
• 102100024810 DNA (cytosine-5)-methyltransferase 3B Human genes 0.000 description 1
• 101710123222 DNA (cytosine-5)-methyltransferase 3B Proteins 0.000 description 1
• 230000004544 DNA amplification Effects 0.000 description 1
• 230000005778 DNA damage Effects 0.000 description 1
• 231100000277 DNA damage Toxicity 0.000 description 1
• 102100036674 DNA damage-binding protein 1 Human genes 0.000 description 1
• 102100038826 DNA helicase MCM8 Human genes 0.000 description 1
• 102100034001 DNA replication licensing factor MCM5 Human genes 0.000 description 1
• 102100033720 DNA replication licensing factor MCM6 Human genes 0.000 description 1
• 102000052510 DNA-Binding Proteins Human genes 0.000 description 1
• 101710096438 DNA-binding protein Proteins 0.000 description 1
• 108090000626 DNA-directed RNA polymerases Proteins 0.000 description 1
• 102000004163 DNA-directed RNA polymerases Human genes 0.000 description 1
• 102100023348 DNA-directed RNA polymerases I, II, and III subunit RPABC2 Human genes 0.000 description 1
• OAUWKHSGCCPXOD-UHFFFAOYSA-N DOC1 Natural products C1=CC(O)=C2C(CC(=O)NCCCCCNCCCNCCCNCCCN)=CNC2=C1 OAUWKHSGCCPXOD-UHFFFAOYSA-N 0.000 description 1
• 102100038587 Death-associated protein kinase 1 Human genes 0.000 description 1
• 102100024354 Dedicator of cytokinesis protein 6 Human genes 0.000 description 1
• 102100024353 Dedicator of cytokinesis protein 9 Human genes 0.000 description 1
• 102100037840 Dehydrogenase/reductase SDR family member 2, mitochondrial Human genes 0.000 description 1
• 108010053770 Deoxyribonucleases Proteins 0.000 description 1
• 102000016911 Deoxyribonucleases Human genes 0.000 description 1
• 102100037458 Dephospho-CoA kinase Human genes 0.000 description 1
• 102100038199 Desmoplakin Human genes 0.000 description 1
• 229920002307 Dextran Polymers 0.000 description 1
• 102100028572 Disabled homolog 2 Human genes 0.000 description 1
• 102100022818 Disintegrin and metalloproteinase domain-containing protein 23 Human genes 0.000 description 1
• 102100024364 Disintegrin and metalloproteinase domain-containing protein 8 Human genes 0.000 description 1
• 102100024361 Disintegrin and metalloproteinase domain-containing protein 9 Human genes 0.000 description 1
• 101710116121 Disintegrin and metalloproteinase domain-containing protein 9 Proteins 0.000 description 1
• 102100029721 DnaJ homolog subfamily B member 1 Human genes 0.000 description 1
• 102100037830 Docking protein 2 Human genes 0.000 description 1
• 102100033140 Dolichyldiphosphatase 1 Human genes 0.000 description 1
• 102100038191 Double-stranded RNA-specific editase 1 Human genes 0.000 description 1
• 201000010374 Down Syndrome Diseases 0.000 description 1
• 101100262461 Drosophila melanogaster vih gene Proteins 0.000 description 1
• 102100036109 Dual specificity protein kinase TTK Human genes 0.000 description 1
• 102100037569 Dual specificity protein phosphatase 10 Human genes 0.000 description 1
• 102100028987 Dual specificity protein phosphatase 2 Human genes 0.000 description 1
• 102100025699 Dual specificity protein phosphatase CDC14B Human genes 0.000 description 1
• 102100033209 Dysbindin domain-containing protein 2 Human genes 0.000 description 1
• 102100032249 Dystonin Human genes 0.000 description 1
• 102100038913 E1A-binding protein p400 Human genes 0.000 description 1
• 102100023877 E3 ubiquitin-protein ligase RBX1 Human genes 0.000 description 1
• 101710095156 E3 ubiquitin-protein ligase RBX1 Proteins 0.000 description 1
• 102100026245 E3 ubiquitin-protein ligase RNF43 Human genes 0.000 description 1
• 102100032058 EARP and GARP complex-interacting protein 1 Human genes 0.000 description 1
• 102100040976 EF-hand and coiled-coil domain-containing protein 1 Human genes 0.000 description 1
• 102100031414 EF-hand domain-containing protein D1 Human genes 0.000 description 1
• 102100032036 EH domain-containing protein 1 Human genes 0.000 description 1
• 102100020865 EKC/KEOPS complex subunit LAGE3 Human genes 0.000 description 1
• 101150001406 EST3 gene Proteins 0.000 description 1
• 239000004278 EU approved seasoning Substances 0.000 description 1
• 102100025137 Early activation antigen CD69 Human genes 0.000 description 1
• 102100021717 Early growth response protein 3 Human genes 0.000 description 1
• 102100035087 Ectoderm-neural cortex protein 1 Human genes 0.000 description 1
• 108010000912 Egg Proteins Proteins 0.000 description 1
• 102000002322 Egg Proteins Human genes 0.000 description 1
• 102100023795 Elafin Human genes 0.000 description 1
• 241000196324 Embryophyta Species 0.000 description 1
• 102100027259 Ena/VASP-like protein Human genes 0.000 description 1
• 102100037241 Endoglin Human genes 0.000 description 1
• 101710180995 Endonuclease 1 Proteins 0.000 description 1
• 102100028773 Endonuclease 8-like 3 Human genes 0.000 description 1
• 102100021771 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase Human genes 0.000 description 1
• 102100031862 Endoplasmic reticulum-Golgi intermediate compartment protein 1 Human genes 0.000 description 1
• 108010041308 Endothelial Growth Factors Proteins 0.000 description 1
• 101710088235 Envelope glycoprotein C homolog Proteins 0.000 description 1
• 108010062466 Enzyme Precursors Proteins 0.000 description 1
• 102000010911 Enzyme Precursors Human genes 0.000 description 1
• 102100030751 Eomesodermin homolog Human genes 0.000 description 1
• 102100024848 Epidermal retinol dehydrogenase 2 Human genes 0.000 description 1
• 101710138625 Epidermal retinol dehydrogenase 2 Proteins 0.000 description 1
• 206010053177 Epidermolysis Diseases 0.000 description 1
• 102100033183 Epithelial membrane protein 1 Human genes 0.000 description 1
• 102100033176 Epithelial membrane protein 2 Human genes 0.000 description 1
• 241000283074 Equus asinus Species 0.000 description 1
• 241000588724 Escherichia coli Species 0.000 description 1
• 102100040002 Eukaryotic translation initiation factor 6 Human genes 0.000 description 1
• 102100038985 Exosome complex component RRP41 Human genes 0.000 description 1
• 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 1
• 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 1
• 101710205374 Extracellular elastase Proteins 0.000 description 1
• 102100022354 FAS-associated factor 2 Human genes 0.000 description 1
• 102100040936 FXYD domain-containing ion transport regulator 6 Human genes 0.000 description 1
• 102100023637 FYVE, RhoGEF and PH domain-containing protein 6 Human genes 0.000 description 1
• 108010071289 Factor XIII Proteins 0.000 description 1
• 108010074860 Factor Xa Proteins 0.000 description 1
• 102100038523 Fascin-3 Human genes 0.000 description 1
• 102100031106 Fatty acid hydroxylase domain-containing protein 2 Human genes 0.000 description 1
• 102100030431 Fatty acid-binding protein, adipocyte Human genes 0.000 description 1
• 102100040683 Fermitin family homolog 1 Human genes 0.000 description 1
• 102100040684 Fermitin family homolog 2 Human genes 0.000 description 1
• 102100031510 Fibrillin-2 Human genes 0.000 description 1
• 108010049003 Fibrinogen Proteins 0.000 description 1
• 102000008946 Fibrinogen Human genes 0.000 description 1
• 102100024785 Fibroblast growth factor 2 Human genes 0.000 description 1
• 108090000379 Fibroblast growth factor 2 Proteins 0.000 description 1
• 108010022355 Fibroins Proteins 0.000 description 1
• 102100038647 Fibroleukin Human genes 0.000 description 1
• 102000017177 Fibromodulin Human genes 0.000 description 1
• 108010013996 Fibromodulin Proteins 0.000 description 1
• 108010067306 Fibronectins Proteins 0.000 description 1
• 102100028065 Fibulin-5 Human genes 0.000 description 1
• 101710195101 Flagellar filament outer layer protein Proteins 0.000 description 1
• 102000004150 Flap endonucleases Human genes 0.000 description 1
• 108090000652 Flap endonucleases Proteins 0.000 description 1
• 101000888214 Flaveria pringlei Serine hydroxymethyltransferase 1, mitochondrial Proteins 0.000 description 1
• 108010091824 Focal Adhesion Kinase 1 Proteins 0.000 description 1
• 102100037813 Focal adhesion kinase 1 Human genes 0.000 description 1
• 102100035139 Folate receptor alpha Human genes 0.000 description 1
• 102100029379 Follistatin-related protein 3 Human genes 0.000 description 1
• 108010008599 Forkhead Box Protein M1 Proteins 0.000 description 1
• 102100020848 Forkhead box protein F2 Human genes 0.000 description 1
• 102100040680 Formin-binding protein 1 Human genes 0.000 description 1
• 102100021261 Frizzled-10 Human genes 0.000 description 1
• 229930091371 Fructose Natural products 0.000 description 1
• 239000005715 Fructose Substances 0.000 description 1
• RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
• 102100037181 Fructose-1,6-bisphosphatase 1 Human genes 0.000 description 1
• 102100022633 Fructose-2,6-bisphosphatase Human genes 0.000 description 1
• 102100027269 Fructose-bisphosphate aldolase C Human genes 0.000 description 1
• 241000233866 Fungi Species 0.000 description 1
• 102100023685 G protein-coupled receptor kinase 5 Human genes 0.000 description 1
• 102100032524 G-protein coupled receptor family C group 5 member C Human genes 0.000 description 1
• 102100036001 G-protein coupled receptor-associated sorting protein 1 Human genes 0.000 description 1
• 102100040861 G0/G1 switch protein 2 Human genes 0.000 description 1
• 102100032340 G2/mitotic-specific cyclin-B1 Human genes 0.000 description 1
• 102100024515 GDP-L-fucose synthase Human genes 0.000 description 1
• 102000009596 GDP-dissociation inhibitor activity proteins Human genes 0.000 description 1
• 108040001987 GDP-dissociation inhibitor activity proteins Proteins 0.000 description 1
• 102100037740 GRB2-associated-binding protein 1 Human genes 0.000 description 1
• 102100036483 GTP-binding protein 8 Human genes 0.000 description 1
• 102100033512 GTP:AMP phosphotransferase AK3, mitochondrial Human genes 0.000 description 1
• 102100024412 GTPase IMAP family member 4 Human genes 0.000 description 1
• 102100024421 GTPase IMAP family member 6 Human genes 0.000 description 1
• 102000002464 Galactosidases Human genes 0.000 description 1
• 108010093031 Galactosidases Proteins 0.000 description 1
• 102100039556 Galectin-4 Human genes 0.000 description 1
• 102000044465 Galectin-7 Human genes 0.000 description 1
• 241000287828 Gallus gallus Species 0.000 description 1
• 102100030916 Gamma-soluble NSF attachment protein Human genes 0.000 description 1
• 102100021337 Gap junction alpha-1 protein Human genes 0.000 description 1
• 102100030525 Gap junction alpha-4 protein Human genes 0.000 description 1
• 102100039417 Gap junction beta-5 protein Human genes 0.000 description 1
• 208000015872 Gaucher disease Diseases 0.000 description 1
• 108010010803 Gelatin Proteins 0.000 description 1
• 108010026132 Gelatinases Proteins 0.000 description 1
• 102000013382 Gelatinases Human genes 0.000 description 1
• 101710112780 Gene 1 protein Proteins 0.000 description 1
• 101000892220 Geobacillus thermodenitrificans (strain NG80-2) Long-chain-alcohol dehydrogenase 1 Proteins 0.000 description 1
• 208000010412 Glaucoma Diseases 0.000 description 1
• 208000032612 Glial tumor Diseases 0.000 description 1
• 206010018338 Glioma Diseases 0.000 description 1
• 102000058062 Glucose Transporter Type 3 Human genes 0.000 description 1
• 102000042092 Glucose transporter family Human genes 0.000 description 1
• 108091052347 Glucose transporter family Proteins 0.000 description 1
• 108010070600 Glucose-6-phosphate isomerase Proteins 0.000 description 1
• 108010055629 Glucosyltransferases Proteins 0.000 description 1
• 102000000340 Glucosyltransferases Human genes 0.000 description 1
• WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 1
• 108010073324 Glutaminase Proteins 0.000 description 1
• 102000009127 Glutaminase Human genes 0.000 description 1
• 102100025945 Glutaredoxin-1 Human genes 0.000 description 1
• 102100028603 Glutaryl-CoA dehydrogenase, mitochondrial Human genes 0.000 description 1
• 102100023523 Glutathione S-transferase Mu 4 Human genes 0.000 description 1
• 102100033044 Glutathione peroxidase 2 Human genes 0.000 description 1
• 102100033053 Glutathione peroxidase 3 Human genes 0.000 description 1
• 102000005720 Glutathione transferase Human genes 0.000 description 1
• 108010070675 Glutathione transferase Proteins 0.000 description 1
• 102100022556 Glycerol-3-phosphate dehydrogenase 1-like protein Human genes 0.000 description 1
• 102100021192 Glycerophosphocholine phosphodiesterase GPCPD1 Human genes 0.000 description 1
• 101710115777 Glycine-rich cell wall structural protein 2 Proteins 0.000 description 1
• 101710168683 Glycine-rich protein 1 Proteins 0.000 description 1
• 102100023849 Glycophorin-C Human genes 0.000 description 1
• 102000028180 Glycophorins Human genes 0.000 description 1
• 108091005250 Glycophorins Proteins 0.000 description 1
• 102100034227 Grainyhead-like protein 2 homolog Human genes 0.000 description 1
• 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 description 1
• 102100039620 Granulocyte-macrophage colony-stimulating factor Human genes 0.000 description 1
• 102100031153 Growth arrest and DNA damage-inducible protein GADD45 beta Human genes 0.000 description 1
• 102100031487 Growth arrest-specific protein 6 Human genes 0.000 description 1
• 102100033067 Growth factor receptor-bound protein 2 Human genes 0.000 description 1
• 102100040896 Growth/differentiation factor 15 Human genes 0.000 description 1
• 102100033321 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Human genes 0.000 description 1
• 102100032611 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Human genes 0.000 description 1
• NYHBQMYGNKIUIF-UUOKFMHZSA-N Guanosine Chemical compound C1=NC=2C(=O)NC(N)=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O NYHBQMYGNKIUIF-UUOKFMHZSA-N 0.000 description 1
• 102100028963 Guanylate cyclase soluble subunit beta-2 Human genes 0.000 description 1
• 102100028541 Guanylate-binding protein 2 Human genes 0.000 description 1
• 102100028490 HEAT repeat-containing protein 5A Human genes 0.000 description 1
• 101150009006 HIS3 gene Proteins 0.000 description 1
• 102100030595 HLA class II histocompatibility antigen gamma chain Human genes 0.000 description 1
• 102100033079 HLA class II histocompatibility antigen, DM alpha chain Human genes 0.000 description 1
• 102100031547 HLA class II histocompatibility antigen, DO alpha chain Human genes 0.000 description 1
• 102100036242 HLA class II histocompatibility antigen, DQ alpha 2 chain Human genes 0.000 description 1
• 102100036241 HLA class II histocompatibility antigen, DQ beta 1 chain Human genes 0.000 description 1
• 102100040505 HLA class II histocompatibility antigen, DR alpha chain Human genes 0.000 description 1
• 102100040485 HLA class II histocompatibility antigen, DRB1 beta chain Human genes 0.000 description 1
• 108010088729 HLA-A*02:01 antigen Proteins 0.000 description 1
• 108010050568 HLA-DM antigens Proteins 0.000 description 1
• 108010086786 HLA-DQA1 antigen Proteins 0.000 description 1
• 108010065026 HLA-DQB1 antigen Proteins 0.000 description 1
• 108010067802 HLA-DR alpha-Chains Proteins 0.000 description 1
• 108010039343 HLA-DRB1 Chains Proteins 0.000 description 1
• 101150006108 HSPB7 gene Proteins 0.000 description 1
• 102100032489 Heat shock 70 kDa protein 13 Human genes 0.000 description 1
• 102100028789 Heat shock protein HSP 90-alpha A2 Human genes 0.000 description 1
• 102100023036 Heat shock protein beta-7 Human genes 0.000 description 1
• 101800000791 Hemagglutinin-esterase-fusion glycoprotein chain 1 Proteins 0.000 description 1
• 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 description 1
• 102100028006 Heme oxygenase 1 Human genes 0.000 description 1
• 102100027685 Hemoglobin subunit alpha Human genes 0.000 description 1
• 108010054147 Hemoglobins Proteins 0.000 description 1
• 102000001554 Hemoglobins Human genes 0.000 description 1
• 229920002971 Heparan sulfate Polymers 0.000 description 1
• 102100030500 Heparin cofactor 2 Human genes 0.000 description 1
• 108010020382 Hepatocyte Nuclear Factor 1-alpha Proteins 0.000 description 1
• 102100022123 Hepatocyte nuclear factor 1-beta Human genes 0.000 description 1
• 102100028818 Heterogeneous nuclear ribonucleoprotein L Human genes 0.000 description 1
• 102100033998 Heterogeneous nuclear ribonucleoprotein U-like protein 1 Human genes 0.000 description 1
• 102100029217 High affinity cationic amino acid transporter 1 Human genes 0.000 description 1
• 102100022132 High affinity immunoglobulin epsilon receptor subunit gamma Human genes 0.000 description 1
• 102100022130 High mobility group protein B3 Human genes 0.000 description 1
• 102100028999 High mobility group protein HMGI-C Human genes 0.000 description 1
• 102100028993 Hippocalcin-like protein 1 Human genes 0.000 description 1
• 102100039265 Histone H2A type 1-C Human genes 0.000 description 1
• 102100023919 Histone H2A.Z Human genes 0.000 description 1
• 102100030689 Histone H2B type 1-D Human genes 0.000 description 1
• 102100022846 Histone acetyltransferase KAT2B Human genes 0.000 description 1
• 101710135007 Histone-like protein p6 Proteins 0.000 description 1
• 102100027755 Histone-lysine N-methyltransferase 2C Human genes 0.000 description 1
• 102100022107 Holliday junction recognition protein Human genes 0.000 description 1
• 102100023604 Homeobox and leucine zipper protein Homez Human genes 0.000 description 1
• 102100022373 Homeobox protein DLX-5 Human genes 0.000 description 1
• 102100025061 Homeobox protein Hox-B7 Human genes 0.000 description 1
• 102100022597 Homeobox protein Hox-C9 Human genes 0.000 description 1
• 102100039545 Homeobox protein Hox-D11 Human genes 0.000 description 1
• 102100037102 Homeobox protein MOX-2 Human genes 0.000 description 1
• 102100027893 Homeobox protein Nkx-2.1 Human genes 0.000 description 1
• 101000928753 Homo sapiens 11-beta-hydroxysteroid dehydrogenase 1 Proteins 0.000 description 1
• 101000845090 Homo sapiens 11-beta-hydroxysteroid dehydrogenase type 2 Proteins 0.000 description 1
• 101001126430 Homo sapiens 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Proteins 0.000 description 1
• 101001031333 Homo sapiens 17-beta-hydroxysteroid dehydrogenase type 6 Proteins 0.000 description 1
• 101000590272 Homo sapiens 26S proteasome non-ATPase regulatory subunit 2 Proteins 0.000 description 1
• 101001090865 Homo sapiens 26S proteasome regulatory subunit 7 Proteins 0.000 description 1
• 101000872461 Homo sapiens 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Proteins 0.000 description 1
• 101000835276 Homo sapiens 3-ketoacyl-CoA thiolase, mitochondrial Proteins 0.000 description 1
• 101000640855 Homo sapiens 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Proteins 0.000 description 1
• 101000691538 Homo sapiens 39S ribosomal protein L12, mitochondrial Proteins 0.000 description 1
• 101001107433 Homo sapiens 39S ribosomal protein L23, mitochondrial Proteins 0.000 description 1
• 101000704060 Homo sapiens 40S ribosomal protein S29 Proteins 0.000 description 1
• 101000694288 Homo sapiens 40S ribosomal protein SA Proteins 0.000 description 1
• 101000895045 Homo sapiens 5-azacytidine-induced protein 2 Proteins 0.000 description 1
• 101000691878 Homo sapiens 60S acidic ribosomal protein P2 Proteins 0.000 description 1
• 101000753696 Homo sapiens 60S ribosomal protein L27a Proteins 0.000 description 1
• 101000716179 Homo sapiens 60S ribosomal protein L39 Proteins 0.000 description 1
• 101000627872 Homo sapiens 72 kDa type IV collagenase Proteins 0.000 description 1
• 101000779382 Homo sapiens A-kinase anchor protein 12 Proteins 0.000 description 1
• 101000774738 Homo sapiens A-kinase anchor protein 2 Proteins 0.000 description 1
• 101000890594 Homo sapiens A-kinase anchor protein 8 Proteins 0.000 description 1
• 101000974441 Homo sapiens ADP-ribosylation factor-like protein 5A Proteins 0.000 description 1
• 101000833180 Homo sapiens AF4/FMR2 family member 1 Proteins 0.000 description 1
• 101000924636 Homo sapiens AP-1 complex subunit mu-2 Proteins 0.000 description 1
• 101000768016 Homo sapiens AP-1 complex subunit sigma-2 Proteins 0.000 description 1
• 101000779216 Homo sapiens AP-1 complex-associated regulatory protein Proteins 0.000 description 1
• 101000732341 Homo sapiens AP-2 complex subunit beta Proteins 0.000 description 1
• 101000905799 Homo sapiens ATP synthase F(0) complex subunit C1, mitochondrial Proteins 0.000 description 1
• 101000936262 Homo sapiens ATP synthase subunit alpha, mitochondrial Proteins 0.000 description 1
• 101000730838 Homo sapiens ATP-dependent 6-phosphofructokinase, muscle type Proteins 0.000 description 1
• 101000907886 Homo sapiens ATP-dependent RNA helicase DHX15 Proteins 0.000 description 1
• 101001051808 Homo sapiens ATPase MORC2 Proteins 0.000 description 1
• 101000975753 Homo sapiens Acid ceramidase Proteins 0.000 description 1
• 101000959247 Homo sapiens Actin, alpha cardiac muscle 1 Proteins 0.000 description 1
• 101000929319 Homo sapiens Actin, aortic smooth muscle Proteins 0.000 description 1
• 101000678433 Homo sapiens Actin, gamma-enteric smooth muscle Proteins 0.000 description 1
• 101000783819 Homo sapiens Actin-binding LIM protein 3 Proteins 0.000 description 1
• 101000925566 Homo sapiens Actin-related protein 2/3 complex subunit 4 Proteins 0.000 description 1
• 101000783751 Homo sapiens Adenosine receptor A2a Proteins 0.000 description 1
• 101000716952 Homo sapiens Adenosylhomocysteinase Proteins 0.000 description 1
• 101000775045 Homo sapiens Adhesion G protein-coupled receptor F5 Proteins 0.000 description 1
• 101000928189 Homo sapiens Adhesion G protein-coupled receptor L2 Proteins 0.000 description 1
• 101000833122 Homo sapiens Adipocyte enhancer-binding protein 1 Proteins 0.000 description 1
• 101000928511 Homo sapiens Akirin-1 Proteins 0.000 description 1
• 101000780443 Homo sapiens Alcohol dehydrogenase 1A Proteins 0.000 description 1
• 101000780463 Homo sapiens Alcohol dehydrogenase 1C Proteins 0.000 description 1
• 101000718041 Homo sapiens Aldo-keto reductase family 1 member B10 Proteins 0.000 description 1
• 101000690301 Homo sapiens Aldo-keto reductase family 1 member C4 Proteins 0.000 description 1
• 101000823116 Homo sapiens Alpha-1-antitrypsin Proteins 0.000 description 1
• 101000779871 Homo sapiens Alpha-amylase 1A Proteins 0.000 description 1
• 101000891982 Homo sapiens Alpha-crystallin B chain Proteins 0.000 description 1
• 101000615966 Homo sapiens Alpha-mannosidase 2x Proteins 0.000 description 1
• 101000890401 Homo sapiens Amyloid beta precursor like protein 2 Proteins 0.000 description 1
• 101000779315 Homo sapiens Anaphase-promoting complex subunit 10 Proteins 0.000 description 1
• 101000924552 Homo sapiens Angiopoietin-1 Proteins 0.000 description 1
• 101000693081 Homo sapiens Angiopoietin-related protein 2 Proteins 0.000 description 1
• 101000694621 Homo sapiens Ankyrin repeat and SAM domain-containing protein 1A Proteins 0.000 description 1
• 101000959738 Homo sapiens Annexin A1 Proteins 0.000 description 1
• 101000780122 Homo sapiens Annexin A5 Proteins 0.000 description 1
• 101000780137 Homo sapiens Annexin A6 Proteins 0.000 description 1
• 101000775021 Homo sapiens Anterior gradient protein 2 homolog Proteins 0.000 description 1
• 101000975752 Homo sapiens Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 Proteins 0.000 description 1
• 101000785775 Homo sapiens Arrestin domain-containing protein 3 Proteins 0.000 description 1
• 101000961044 Homo sapiens Atrial natriuretic peptide receptor 1 Proteins 0.000 description 1
• 101000874361 Homo sapiens Autism susceptibility gene 2 protein Proteins 0.000 description 1
• 101000874566 Homo sapiens Axin-1 Proteins 0.000 description 1
• 101000697498 Homo sapiens BAG family molecular chaperone regulator 5 Proteins 0.000 description 1
• 101000596896 Homo sapiens BDNF/NT-3 growth factors receptor Proteins 0.000 description 1
• 101001049975 Homo sapiens Band 4.1-like protein 3 Proteins 0.000 description 1
• 101000798490 Homo sapiens Bcl-2-associated transcription factor 1 Proteins 0.000 description 1
• 101000887635 Homo sapiens Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 Proteins 0.000 description 1
• 101000937508 Homo sapiens Beta-1,4-galactosyltransferase 7 Proteins 0.000 description 1
• 101000899390 Homo sapiens Bone morphogenetic protein 6 Proteins 0.000 description 1
• 101000896771 Homo sapiens Bromodomain and PHD finger-containing protein 3 Proteins 0.000 description 1
• 101000896419 Homo sapiens Bystin Proteins 0.000 description 1
• 101000777471 Homo sapiens C-C motif chemokine 4 Proteins 0.000 description 1
• 101000858088 Homo sapiens C-X-C motif chemokine 10 Proteins 0.000 description 1
• 101000912618 Homo sapiens C-type lectin domain family 2 member B Proteins 0.000 description 1
• 101000576898 Homo sapiens C-type mannose receptor 2 Proteins 0.000 description 1
• 101000740689 Homo sapiens C4b-binding protein beta chain Proteins 0.000 description 1
• 101000945426 Homo sapiens CB1 cannabinoid receptor-interacting protein 1 Proteins 0.000 description 1
• 101100438661 Homo sapiens CCDC167 gene Proteins 0.000 description 1
• 101000942590 Homo sapiens CCR4-NOT transcription complex subunit 9 Proteins 0.000 description 1
• 101000946856 Homo sapiens CD83 antigen Proteins 0.000 description 1
• 101000776617 Homo sapiens CGG triplet repeat-binding protein 1 Proteins 0.000 description 1
• 101000899994 Homo sapiens COMM domain-containing protein 5 Proteins 0.000 description 1
• 101000860854 Homo sapiens COUP transcription factor 1 Proteins 0.000 description 1
• 101000860860 Homo sapiens COUP transcription factor 2 Proteins 0.000 description 1
• 101000725950 Homo sapiens CTD small phosphatase-like protein Proteins 0.000 description 1
• 101000762243 Homo sapiens Cadherin-13 Proteins 0.000 description 1
• 101000762242 Homo sapiens Cadherin-15 Proteins 0.000 description 1
• 101000714553 Homo sapiens Cadherin-3 Proteins 0.000 description 1
• 101000794587 Homo sapiens Cadherin-5 Proteins 0.000 description 1
• 101000580357 Homo sapiens Calcipressin-1 Proteins 0.000 description 1
• 101000943642 Homo sapiens Calcium homeostasis endoplasmic reticulum protein Proteins 0.000 description 1
• 101000714589 Homo sapiens Calcium-binding and coiled-coil domain-containing protein 1 Proteins 0.000 description 1
• 101000935132 Homo sapiens Calcium-binding tyrosine phosphorylation-regulated protein Proteins 0.000 description 1
• 101000910297 Homo sapiens Caldesmon Proteins 0.000 description 1
• 101000945309 Homo sapiens Calmodulin-binding transcription activator 1 Proteins 0.000 description 1
• 101000919200 Homo sapiens Calpain small subunit 2 Proteins 0.000 description 1
• 101000945318 Homo sapiens Calponin-1 Proteins 0.000 description 1
• 101000856237 Homo sapiens Cancer/testis antigen 1 Proteins 0.000 description 1
• 101000882994 Homo sapiens Carbohydrate sulfotransferase 5 Proteins 0.000 description 1
• 101000867855 Homo sapiens Carbonic anhydrase 12 Proteins 0.000 description 1
• 101000892026 Homo sapiens Casein kinase II subunit alpha Proteins 0.000 description 1
• 101000892015 Homo sapiens Casein kinase II subunit alpha' Proteins 0.000 description 1
• 101000761247 Homo sapiens Caspase recruitment domain-containing protein 8 Proteins 0.000 description 1
• 101000933218 Homo sapiens Cathepsin F Proteins 0.000 description 1
• 101000983577 Homo sapiens Cathepsin L2 Proteins 0.000 description 1
• 101000715467 Homo sapiens Caveolin-1 Proteins 0.000 description 1
• 101000740981 Homo sapiens Caveolin-2 Proteins 0.000 description 1
• 101000868629 Homo sapiens Cell cycle progression protein 1 Proteins 0.000 description 1
• 101000884317 Homo sapiens Cell division cycle protein 20 homolog Proteins 0.000 description 1
• 101001099865 Homo sapiens Cellular retinoic acid-binding protein 1 Proteins 0.000 description 1
• 101001099851 Homo sapiens Cellular retinoic acid-binding protein 2 Proteins 0.000 description 1
• 101000883325 Homo sapiens Chitinase-3-like protein 2 Proteins 0.000 description 1
• 101000906636 Homo sapiens Chloride intracellular channel protein 4 Proteins 0.000 description 1
• 101000948115 Homo sapiens Choline transporter-like protein 2 Proteins 0.000 description 1
• 101000879734 Homo sapiens Chondrolectin Proteins 0.000 description 1
• 101000741348 Homo sapiens Chromatin assembly factor 1 subunit A Proteins 0.000 description 1
• 101000749331 Homo sapiens Claudin-1 Proteins 0.000 description 1
• 101000882901 Homo sapiens Claudin-2 Proteins 0.000 description 1
• 101000882896 Homo sapiens Claudin-5 Proteins 0.000 description 1
• 101000772631 Homo sapiens Coiled-coil domain-containing protein 180 Proteins 0.000 description 1
• 101000910797 Homo sapiens Coiled-coil domain-containing protein 85A Proteins 0.000 description 1
• 101000993285 Homo sapiens Collagen alpha-1(III) chain Proteins 0.000 description 1
• 101000901150 Homo sapiens Collagen alpha-1(IV) chain Proteins 0.000 description 1
• 101000941581 Homo sapiens Collagen alpha-1(VI) chain Proteins 0.000 description 1
• 101000909498 Homo sapiens Collagen alpha-1(VII) chain Proteins 0.000 description 1
• 101000875067 Homo sapiens Collagen alpha-2(I) chain Proteins 0.000 description 1
• 101000710876 Homo sapiens Collagen alpha-2(IV) chain Proteins 0.000 description 1
• 101000941585 Homo sapiens Collagen alpha-2(VI) chain Proteins 0.000 description 1
• 101000909528 Homo sapiens Collectin-12 Proteins 0.000 description 1
• 101000740726 Homo sapiens Complement C1q subcomponent subunit A Proteins 0.000 description 1
• 101000794265 Homo sapiens Complement C1q tumor necrosis factor-related protein 5 Proteins 0.000 description 1
• 101000702152 Homo sapiens Cornifin-B Proteins 0.000 description 1
• 101000905723 Homo sapiens Cyclic AMP-dependent transcription factor ATF-7 Proteins 0.000 description 1
• 101000944357 Homo sapiens Cyclin-dependent kinase 16 Proteins 0.000 description 1
• 101000737813 Homo sapiens Cyclin-dependent kinase 2-associated protein 1 Proteins 0.000 description 1
• 101000944365 Homo sapiens Cyclin-dependent kinase inhibitor 1C Proteins 0.000 description 1
• 101000945639 Homo sapiens Cyclin-dependent kinase inhibitor 3 Proteins 0.000 description 1
• 101000710200 Homo sapiens Cyclin-dependent kinases regulatory subunit 1 Proteins 0.000 description 1
• 101000921786 Homo sapiens Cystatin-A Proteins 0.000 description 1
• 101000922020 Homo sapiens Cysteine and glycine-rich protein 1 Proteins 0.000 description 1
• 101000922196 Homo sapiens Cysteine/serine-rich nuclear protein 1 Proteins 0.000 description 1
• 101000725164 Homo sapiens Cytochrome P450 1B1 Proteins 0.000 description 1
• 101000855328 Homo sapiens Cytochrome P450 2S1 Proteins 0.000 description 1
• 101000607486 Homo sapiens Cytochrome b-c1 complex subunit 1, mitochondrial Proteins 0.000 description 1
• 101000922386 Homo sapiens Cytochrome b5 Proteins 0.000 description 1
• 101000875933 Homo sapiens Cytochrome c oxidase copper chaperone Proteins 0.000 description 1
• 101000922367 Homo sapiens Cytochrome c oxidase subunit 6B1 Proteins 0.000 description 1
• 101000861049 Homo sapiens Cytochrome c oxidase subunit 6C Proteins 0.000 description 1
• 101000916686 Homo sapiens Cytohesin-interacting protein Proteins 0.000 description 1
• 101001033280 Homo sapiens Cytokine receptor common subunit beta Proteins 0.000 description 1
• 101001107795 Homo sapiens Cytosolic Fe-S cluster assembly factor NUBP2 Proteins 0.000 description 1
• 101000946505 Homo sapiens Cytosolic carboxypeptidase 1 Proteins 0.000 description 1
• 101000877468 Homo sapiens Cytosolic endo-beta-N-acetylglucosaminidase Proteins 0.000 description 1
• 101000739890 Homo sapiens D-3-phosphoglycerate dehydrogenase Proteins 0.000 description 1
• 101000865183 Homo sapiens DEP domain-containing mTOR-interacting protein Proteins 0.000 description 1
• 101000957174 Homo sapiens DNA helicase MCM8 Proteins 0.000 description 1
• 101001017545 Homo sapiens DNA replication licensing factor MCM5 Proteins 0.000 description 1
• 101001018484 Homo sapiens DNA replication licensing factor MCM6 Proteins 0.000 description 1
• 101000686009 Homo sapiens DNA-directed RNA polymerases I, II, and III subunit RPABC2 Proteins 0.000 description 1
• 101000956145 Homo sapiens Death-associated protein kinase 1 Proteins 0.000 description 1
• 101001052950 Homo sapiens Dedicator of cytokinesis protein 6 Proteins 0.000 description 1
• 101001052948 Homo sapiens Dedicator of cytokinesis protein 9 Proteins 0.000 description 1
• 101001053992 Homo sapiens Deleted in lung and esophageal cancer protein 1 Proteins 0.000 description 1
• 101000915391 Homo sapiens Disabled homolog 2 Proteins 0.000 description 1
• 101000756727 Homo sapiens Disintegrin and metalloproteinase domain-containing protein 23 Proteins 0.000 description 1
• 101000756756 Homo sapiens Disintegrin and metalloproteinase domain-containing protein 28 Proteins 0.000 description 1
• 101000832767 Homo sapiens Disintegrin and metalloproteinase domain-containing protein 8 Proteins 0.000 description 1
• 101000866018 Homo sapiens DnaJ homolog subfamily B member 1 Proteins 0.000 description 1
• 101000805166 Homo sapiens Docking protein 2 Proteins 0.000 description 1
• 101000848781 Homo sapiens Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 1 Proteins 0.000 description 1
• 101000742223 Homo sapiens Double-stranded RNA-specific editase 1 Proteins 0.000 description 1
• 101000659223 Homo sapiens Dual specificity protein kinase TTK Proteins 0.000 description 1
• 101000881127 Homo sapiens Dual specificity protein phosphatase 10 Proteins 0.000 description 1
• 101000838335 Homo sapiens Dual specificity protein phosphatase 2 Proteins 0.000 description 1
• 101000932592 Homo sapiens Dual specificity protein phosphatase CDC14B Proteins 0.000 description 1
• 101000966403 Homo sapiens Dynein light chain 1, cytoplasmic Proteins 0.000 description 1
• 101000871249 Homo sapiens Dysbindin domain-containing protein 2 Proteins 0.000 description 1
• 101001016186 Homo sapiens Dystonin Proteins 0.000 description 1
• 101000882371 Homo sapiens E1A-binding protein p400 Proteins 0.000 description 1
• 101000620132 Homo sapiens E3 ubiquitin-protein ligase LNX Proteins 0.000 description 1
• 101000692702 Homo sapiens E3 ubiquitin-protein ligase RNF43 Proteins 0.000 description 1
• 101000921326 Homo sapiens EARP and GARP complex-interacting protein 1 Proteins 0.000 description 1
• 101000815518 Homo sapiens EF-hand and coiled-coil domain-containing protein 1 Proteins 0.000 description 1
• 101000866909 Homo sapiens EF-hand domain-containing protein D1 Proteins 0.000 description 1
• 101000921221 Homo sapiens EH domain-containing protein 1 Proteins 0.000 description 1
• 101001137983 Homo sapiens EKC/KEOPS complex subunit LAGE3 Proteins 0.000 description 1
• 101000934374 Homo sapiens Early activation antigen CD69 Proteins 0.000 description 1
• 101000896450 Homo sapiens Early growth response protein 3 Proteins 0.000 description 1
• 101000877456 Homo sapiens Ectoderm-neural cortex protein 1 Proteins 0.000 description 1
• 101001048718 Homo sapiens Elafin Proteins 0.000 description 1
• 101001057143 Homo sapiens Ena/VASP-like protein Proteins 0.000 description 1
• 101001123819 Homo sapiens Endonuclease 8-like 3 Proteins 0.000 description 1
• 101000615944 Homo sapiens Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase Proteins 0.000 description 1
• 101000920804 Homo sapiens Endoplasmic reticulum-Golgi intermediate compartment protein 1 Proteins 0.000 description 1
• 101000851937 Homo sapiens Endothelial PAS domain-containing protein 1 Proteins 0.000 description 1
• 101000898310 Homo sapiens Enhancer of filamentation 1 Proteins 0.000 description 1
• 101001064167 Homo sapiens Eomesodermin homolog Proteins 0.000 description 1
• 101000850989 Homo sapiens Epithelial membrane protein 1 Proteins 0.000 description 1
• 101000851002 Homo sapiens Epithelial membrane protein 2 Proteins 0.000 description 1
• 101000959746 Homo sapiens Eukaryotic translation initiation factor 6 Proteins 0.000 description 1
• 101000882162 Homo sapiens Exosome complex component RRP41 Proteins 0.000 description 1
• 101000824586 Homo sapiens FAS-associated factor 2 Proteins 0.000 description 1
• 101100012856 Homo sapiens FGD6 gene Proteins 0.000 description 1
• 101000893722 Homo sapiens FXYD domain-containing ion transport regulator 6 Proteins 0.000 description 1
• 101001030532 Homo sapiens Fascin-3 Proteins 0.000 description 1
• 101001066086 Homo sapiens Fatty acid hydroxylase domain-containing protein 2 Proteins 0.000 description 1
• 101001062864 Homo sapiens Fatty acid-binding protein, adipocyte Proteins 0.000 description 1
• 101000892670 Homo sapiens Fermitin family homolog 1 Proteins 0.000 description 1
• 101000846890 Homo sapiens Fibrillin-2 Proteins 0.000 description 1
• 101001031613 Homo sapiens Fibroleukin Proteins 0.000 description 1
• 101001060252 Homo sapiens Fibulin-5 Proteins 0.000 description 1
• 101000878301 Homo sapiens Filamin A-interacting protein 1-like Proteins 0.000 description 1
• 101001023230 Homo sapiens Folate receptor alpha Proteins 0.000 description 1
• 101001062529 Homo sapiens Follistatin-related protein 3 Proteins 0.000 description 1
• 101000931494 Homo sapiens Forkhead box protein F1 Proteins 0.000 description 1
• 101000931482 Homo sapiens Forkhead box protein F2 Proteins 0.000 description 1
• 101000892722 Homo sapiens Formin-binding protein 1 Proteins 0.000 description 1
• 101000819451 Homo sapiens Frizzled-10 Proteins 0.000 description 1
• 101001028852 Homo sapiens Fructose-1,6-bisphosphatase 1 Proteins 0.000 description 1
• 101000823467 Homo sapiens Fructose-2,6-bisphosphatase Proteins 0.000 description 1
• 101000836545 Homo sapiens Fructose-bisphosphate aldolase C Proteins 0.000 description 1
• 101000829476 Homo sapiens G protein-coupled receptor kinase 5 Proteins 0.000 description 1
• 101001014685 Homo sapiens G-protein coupled receptor family C group 5 member C Proteins 0.000 description 1
• 101000893656 Homo sapiens G0/G1 switch protein 2 Proteins 0.000 description 1
• 101000868643 Homo sapiens G2/mitotic-specific cyclin-B1 Proteins 0.000 description 1
• 101001052793 Homo sapiens GDP-L-fucose synthase Proteins 0.000 description 1
• 101100503886 Homo sapiens GPRASP1 gene Proteins 0.000 description 1
• 101001024897 Homo sapiens GRB2-associated-binding protein 1 Proteins 0.000 description 1
• 101001071663 Homo sapiens GTP-binding protein 8 Proteins 0.000 description 1
• 101000833375 Homo sapiens GTPase IMAP family member 4 Proteins 0.000 description 1
• 101000833389 Homo sapiens GTPase IMAP family member 6 Proteins 0.000 description 1
• 101000608765 Homo sapiens Galectin-4 Proteins 0.000 description 1
• 101000702693 Homo sapiens Gamma-soluble NSF attachment protein Proteins 0.000 description 1
• 101000894966 Homo sapiens Gap junction alpha-1 protein Proteins 0.000 description 1
• 101000726582 Homo sapiens Gap junction alpha-4 protein Proteins 0.000 description 1
• 101000954104 Homo sapiens Gap junction beta-1 protein Proteins 0.000 description 1
• 101000954092 Homo sapiens Gap junction beta-2 protein Proteins 0.000 description 1
• 101000889145 Homo sapiens Gap junction beta-5 protein Proteins 0.000 description 1
• 101000856983 Homo sapiens Glutaredoxin-1 Proteins 0.000 description 1
• 101001058943 Homo sapiens Glutaryl-CoA dehydrogenase, mitochondrial Proteins 0.000 description 1
• 101000906399 Homo sapiens Glutathione S-transferase Mu 4 Proteins 0.000 description 1
• 101000871129 Homo sapiens Glutathione peroxidase 2 Proteins 0.000 description 1
• 101000871067 Homo sapiens Glutathione peroxidase 3 Proteins 0.000 description 1
• 101000900194 Homo sapiens Glycerol-3-phosphate dehydrogenase 1-like protein Proteins 0.000 description 1
• 101001040698 Homo sapiens Glycerophosphocholine phosphodiesterase GPCPD1 Proteins 0.000 description 1
• 101000905336 Homo sapiens Glycophorin-C Proteins 0.000 description 1
• 101001069929 Homo sapiens Grainyhead-like protein 2 homolog Proteins 0.000 description 1
• 101001066164 Homo sapiens Growth arrest and DNA damage-inducible protein GADD45 beta Proteins 0.000 description 1
• 101000923005 Homo sapiens Growth arrest-specific protein 6 Proteins 0.000 description 1
• 101000871017 Homo sapiens Growth factor receptor-bound protein 2 Proteins 0.000 description 1
• 101000893549 Homo sapiens Growth/differentiation factor 15 Proteins 0.000 description 1
• 101000926795 Homo sapiens Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Proteins 0.000 description 1
• 101001070508 Homo sapiens Guanine nucleotide-binding protein G(i) subunit alpha-2 Proteins 0.000 description 1
• 101001014590 Homo sapiens Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Proteins 0.000 description 1
• 101001014594 Homo sapiens Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Proteins 0.000 description 1
• 101001059095 Homo sapiens Guanylate cyclase soluble subunit beta-2 Proteins 0.000 description 1
• 101001058858 Homo sapiens Guanylate-binding protein 2 Proteins 0.000 description 1
• 101000839976 Homo sapiens HEAT repeat-containing protein 5A Proteins 0.000 description 1
• 101001082627 Homo sapiens HLA class II histocompatibility antigen gamma chain Proteins 0.000 description 1
• 101000866278 Homo sapiens HLA class II histocompatibility antigen, DO alpha chain Proteins 0.000 description 1
• 101001016638 Homo sapiens Heat shock 70 kDa protein 13 Proteins 0.000 description 1
• 101001016865 Homo sapiens Heat shock protein HSP 90-alpha Proteins 0.000 description 1
• 101001078626 Homo sapiens Heat shock protein HSP 90-alpha A2 Proteins 0.000 description 1
• 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 description 1
• 101001079623 Homo sapiens Heme oxygenase 1 Proteins 0.000 description 1
• 101001009007 Homo sapiens Hemoglobin subunit alpha Proteins 0.000 description 1
• 101001082432 Homo sapiens Heparin cofactor 2 Proteins 0.000 description 1
• 101001045751 Homo sapiens Hepatocyte nuclear factor 1-alpha Proteins 0.000 description 1
• 101001045758 Homo sapiens Hepatocyte nuclear factor 1-beta Proteins 0.000 description 1
• 101000839078 Homo sapiens Heterogeneous nuclear ribonucleoprotein L Proteins 0.000 description 1
• 101001017567 Homo sapiens Heterogeneous nuclear ribonucleoprotein U-like protein 1 Proteins 0.000 description 1
• 101000824104 Homo sapiens High affinity immunoglobulin epsilon receptor subunit gamma Proteins 0.000 description 1
• 101001045794 Homo sapiens High mobility group protein B3 Proteins 0.000 description 1
• 101000986379 Homo sapiens High mobility group protein HMGI-C Proteins 0.000 description 1
• 101000838883 Homo sapiens Hippocalcin-like protein 1 Proteins 0.000 description 1
• 101001036109 Homo sapiens Histone H2A type 1-C Proteins 0.000 description 1
• 101000905054 Homo sapiens Histone H2A.Z Proteins 0.000 description 1
• 101001084684 Homo sapiens Histone H2B type 1-D Proteins 0.000 description 1
• 101001047006 Homo sapiens Histone acetyltransferase KAT2B Proteins 0.000 description 1
• 101001008892 Homo sapiens Histone-lysine N-methyltransferase 2C Proteins 0.000 description 1
• 101001045907 Homo sapiens Holliday junction recognition protein Proteins 0.000 description 1
• 101001048457 Homo sapiens Homeobox and leucine zipper protein Homez Proteins 0.000 description 1
• 101000901627 Homo sapiens Homeobox protein DLX-5 Proteins 0.000 description 1
• 101001077539 Homo sapiens Homeobox protein Hox-B7 Proteins 0.000 description 1
• 101001045140 Homo sapiens Homeobox protein Hox-C9 Proteins 0.000 description 1
• 101000962591 Homo sapiens Homeobox protein Hox-D11 Proteins 0.000 description 1
• 101000955037 Homo sapiens Homeobox protein MOX-2 Proteins 0.000 description 1
• 101001081176 Homo sapiens Hyaluronan mediated motility receptor Proteins 0.000 description 1
• 101001035951 Homo sapiens Hyaluronan-binding protein 2 Proteins 0.000 description 1
• 101000962526 Homo sapiens Hyaluronidase-2 Proteins 0.000 description 1
• 101001035752 Homo sapiens Hydroxycarboxylic acid receptor 3 Proteins 0.000 description 1
• 101001082574 Homo sapiens Hypoxia-inducible factor 1-alpha inhibitor Proteins 0.000 description 1
• 101100452137 Homo sapiens IGF2BP3 gene Proteins 0.000 description 1
• 101100018617 Homo sapiens IGLL1 gene Proteins 0.000 description 1
• 101000961145 Homo sapiens Immunoglobulin heavy constant gamma 3 Proteins 0.000 description 1
• 101000840257 Homo sapiens Immunoglobulin kappa constant Proteins 0.000 description 1
• 101001001473 Homo sapiens Importin subunit alpha-4 Proteins 0.000 description 1
• 101000691610 Homo sapiens Inactive phospholipase C-like protein 2 Proteins 0.000 description 1
• 101001103039 Homo sapiens Inactive tyrosine-protein kinase transmembrane receptor ROR1 Proteins 0.000 description 1
• 101000852852 Homo sapiens Innate immunity activator protein Proteins 0.000 description 1
• 101000993959 Homo sapiens Inositol 1,4,5-trisphosphate receptor-interacting protein Proteins 0.000 description 1
• 101000993973 Homo sapiens Inositol-pentakisphosphate 2-kinase Proteins 0.000 description 1
• 101001044940 Homo sapiens Insulin-like growth factor-binding protein 2 Proteins 0.000 description 1
• 101001044927 Homo sapiens Insulin-like growth factor-binding protein 3 Proteins 0.000 description 1
• 101000840582 Homo sapiens Insulin-like growth factor-binding protein 6 Proteins 0.000 description 1
• 101001050468 Homo sapiens Integral membrane protein 2B Proteins 0.000 description 1
• 101001035232 Homo sapiens Integrin alpha-9 Proteins 0.000 description 1
• 101001015006 Homo sapiens Integrin beta-4 Proteins 0.000 description 1
• 101001015064 Homo sapiens Integrin beta-6 Proteins 0.000 description 1
• 101001015037 Homo sapiens Integrin beta-7 Proteins 0.000 description 1
• 101001050473 Homo sapiens Intelectin-1 Proteins 0.000 description 1
• 101000976697 Homo sapiens Inter-alpha-trypsin inhibitor heavy chain H1 Proteins 0.000 description 1
• 101001054334 Homo sapiens Interferon beta Proteins 0.000 description 1
• 101000598002 Homo sapiens Interferon regulatory factor 1 Proteins 0.000 description 1
• 101001032345 Homo sapiens Interferon regulatory factor 8 Proteins 0.000 description 1
• 101001076418 Homo sapiens Interleukin-1 receptor type 1 Proteins 0.000 description 1
• 101001076422 Homo sapiens Interleukin-1 receptor type 2 Proteins 0.000 description 1
• 101000599056 Homo sapiens Interleukin-6 receptor subunit beta Proteins 0.000 description 1
• 101001043809 Homo sapiens Interleukin-7 receptor subunit alpha Proteins 0.000 description 1
• 101001053438 Homo sapiens Iroquois-class homeodomain protein IRX-2 Proteins 0.000 description 1
• 101000971351 Homo sapiens KRR1 small subunit processome component homolog Proteins 0.000 description 1
• 101001047041 Homo sapiens Kelch repeat and BTB domain-containing protein 7 Proteins 0.000 description 1
• 101000614627 Homo sapiens Keratin, type I cytoskeletal 13 Proteins 0.000 description 1
• 101000614439 Homo sapiens Keratin, type I cytoskeletal 15 Proteins 0.000 description 1
• 101000998011 Homo sapiens Keratin, type I cytoskeletal 19 Proteins 0.000 description 1
• 101001050274 Homo sapiens Keratin, type I cytoskeletal 9 Proteins 0.000 description 1
• 101001007027 Homo sapiens Keratin, type II cuticular Hb1 Proteins 0.000 description 1
• 101001026977 Homo sapiens Keratin, type II cuticular Hb6 Proteins 0.000 description 1
• 101001056473 Homo sapiens Keratin, type II cytoskeletal 5 Proteins 0.000 description 1
• 101001056452 Homo sapiens Keratin, type II cytoskeletal 6A Proteins 0.000 description 1
• 101001027631 Homo sapiens Kinesin-like protein KIF20B Proteins 0.000 description 1
• 101001050567 Homo sapiens Kinesin-like protein KIF2C Proteins 0.000 description 1
• 101000971521 Homo sapiens Kinetochore scaffold 1 Proteins 0.000 description 1
• 101001139134 Homo sapiens Krueppel-like factor 4 Proteins 0.000 description 1
• 101001139112 Homo sapiens Krueppel-like factor 9 Proteins 0.000 description 1
• 101001003569 Homo sapiens LIM domain only protein 3 Proteins 0.000 description 1
• 101001022948 Homo sapiens LIM domain-binding protein 2 Proteins 0.000 description 1
• 101001047511 Homo sapiens LLGL scribble cell polarity complex component 2 Proteins 0.000 description 1
• 101001047746 Homo sapiens Lamina-associated polypeptide 2, isoform alpha Proteins 0.000 description 1
• 101001047731 Homo sapiens Lamina-associated polypeptide 2, isoforms beta/gamma Proteins 0.000 description 1
• 101000972491 Homo sapiens Laminin subunit alpha-2 Proteins 0.000 description 1
• 101000972488 Homo sapiens Laminin subunit alpha-4 Proteins 0.000 description 1
• 101001008558 Homo sapiens Laminin subunit beta-2 Proteins 0.000 description 1
• 101000946306 Homo sapiens Laminin subunit gamma-1 Proteins 0.000 description 1
• 101001054649 Homo sapiens Latent-transforming growth factor beta-binding protein 2 Proteins 0.000 description 1
• 101001054646 Homo sapiens Latent-transforming growth factor beta-binding protein 3 Proteins 0.000 description 1
• 101001063456 Homo sapiens Leucine-rich repeat-containing G-protein coupled receptor 5 Proteins 0.000 description 1
• 101001042362 Homo sapiens Leukemia inhibitory factor receptor Proteins 0.000 description 1
• 101000984185 Homo sapiens Leukocyte immunoglobulin-like receptor subfamily B member 5 Proteins 0.000 description 1
• 101000980823 Homo sapiens Leukocyte surface antigen CD53 Proteins 0.000 description 1
• 101001138062 Homo sapiens Leukocyte-associated immunoglobulin-like receptor 1 Proteins 0.000 description 1
• 101000942133 Homo sapiens Leupaxin Proteins 0.000 description 1
• 101000780205 Homo sapiens Long-chain-fatty-acid-CoA ligase 5 Proteins 0.000 description 1
• 101001039199 Homo sapiens Low-density lipoprotein receptor-related protein 6 Proteins 0.000 description 1
• 101001090688 Homo sapiens Lymphocyte cytosolic protein 2 Proteins 0.000 description 1
• 101000984710 Homo sapiens Lymphocyte-specific protein 1 Proteins 0.000 description 1
• 101001018100 Homo sapiens Lysozyme C Proteins 0.000 description 1
• 101001005708 Homo sapiens MARVEL domain-containing protein 1 Proteins 0.000 description 1
• 101000972918 Homo sapiens MAX gene-associated protein Proteins 0.000 description 1
• 101000916644 Homo sapiens Macrophage colony-stimulating factor 1 receptor Proteins 0.000 description 1
• 101001056015 Homo sapiens Mannan-binding lectin serine protease 2 Proteins 0.000 description 1
• 101000980026 Homo sapiens Maternal embryonic leucine zipper kinase Proteins 0.000 description 1
• 101000636209 Homo sapiens Matrix-remodeling-associated protein 5 Proteins 0.000 description 1
• 101001055354 Homo sapiens Mediator of RNA polymerase II transcription subunit 6 Proteins 0.000 description 1
• 101001005720 Homo sapiens Melanoma-associated antigen 4 Proteins 0.000 description 1
• 101001005722 Homo sapiens Melanoma-associated antigen 6 Proteins 0.000 description 1
• 101000956335 Homo sapiens Membrane-spanning 4-domains subfamily A member 14 Proteins 0.000 description 1
• 101001014567 Homo sapiens Membrane-spanning 4-domains subfamily A member 7 Proteins 0.000 description 1
• 101000956307 Homo sapiens Membrane-spanning 4-domains subfamily A member 8 Proteins 0.000 description 1
• 101000645296 Homo sapiens Metalloproteinase inhibitor 2 Proteins 0.000 description 1
• 101000947699 Homo sapiens Microfibril-associated glycoprotein 4 Proteins 0.000 description 1
• 101001013999 Homo sapiens Microtubule cross-linking factor 1 Proteins 0.000 description 1
• 101001038443 Homo sapiens Mitochondrial glutamate carrier 1 Proteins 0.000 description 1
• 101000764216 Homo sapiens Mitochondrial import receptor subunit TOM40 homolog Proteins 0.000 description 1
• 101001013832 Homo sapiens Mitochondrial peptide methionine sulfoxide reductase Proteins 0.000 description 1
• 101000882884 Homo sapiens Mitochondrial tRNA methylthiotransferase CDK5RAP1 Proteins 0.000 description 1
• 101000950687 Homo sapiens Mitogen-activated protein kinase 7 Proteins 0.000 description 1
• 101000794228 Homo sapiens Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Proteins 0.000 description 1
• 101000946889 Homo sapiens Monocyte differentiation antigen CD14 Proteins 0.000 description 1
• 101001133056 Homo sapiens Mucin-1 Proteins 0.000 description 1
• 101001133091 Homo sapiens Mucin-20 Proteins 0.000 description 1
• 101000969697 Homo sapiens Multiple PDZ domain protein Proteins 0.000 description 1
• 101000593405 Homo sapiens Myb-related protein B Proteins 0.000 description 1
• 101001030211 Homo sapiens Myc proto-oncogene protein Proteins 0.000 description 1
• 101000589016 Homo sapiens Myomegalin Proteins 0.000 description 1
• 101001128456 Homo sapiens Myosin regulatory light polypeptide 9 Proteins 0.000 description 1
• 101000874528 Homo sapiens N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 Proteins 0.000 description 1
• 101000958771 Homo sapiens N-acylethanolamine-hydrolyzing acid amidase Proteins 0.000 description 1
• 101000906927 Homo sapiens N-chimaerin Proteins 0.000 description 1
• 101000928259 Homo sapiens NADPH:adrenodoxin oxidoreductase, mitochondrial Proteins 0.000 description 1
• 101100294188 Homo sapiens NIN gene Proteins 0.000 description 1
• 101001125322 Homo sapiens Na(+)/H(+) exchange regulatory cofactor NHE-RF2 Proteins 0.000 description 1
• 101001023705 Homo sapiens Nectin-4 Proteins 0.000 description 1
• 101001111320 Homo sapiens Nestin Proteins 0.000 description 1
• 101001014610 Homo sapiens Neuroendocrine secretory protein 55 Proteins 0.000 description 1
• 101001128969 Homo sapiens Neuron navigator 1 Proteins 0.000 description 1
• 101001108364 Homo sapiens Neuronal cell adhesion molecule Proteins 0.000 description 1
• 101000604058 Homo sapiens Neuronal pentraxin-1 Proteins 0.000 description 1
• 101001108246 Homo sapiens Neuronal pentraxin-2 Proteins 0.000 description 1
• 101000603202 Homo sapiens Nicotinamide N-methyltransferase Proteins 0.000 description 1
• 101000996058 Homo sapiens Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 Proteins 0.000 description 1
• 101000632159 Homo sapiens Ninjurin-2 Proteins 0.000 description 1
• 101000597426 Homo sapiens Nuclear RNA export factor 3 Proteins 0.000 description 1
• 101001023768 Homo sapiens Nuclear factor related to kappa-B-binding protein Proteins 0.000 description 1
• 101001103036 Homo sapiens Nuclear receptor ROR-alpha Proteins 0.000 description 1
• 101001109700 Homo sapiens Nuclear receptor subfamily 4 group A member 1 Proteins 0.000 description 1
• 101001109698 Homo sapiens Nuclear receptor subfamily 4 group A member 2 Proteins 0.000 description 1
• 101000991410 Homo sapiens Nucleolar and spindle-associated protein 1 Proteins 0.000 description 1
• 101001109719 Homo sapiens Nucleophosmin Proteins 0.000 description 1
• 101000979629 Homo sapiens Nucleoside diphosphate kinase A Proteins 0.000 description 1
• 101000979623 Homo sapiens Nucleoside diphosphate kinase B Proteins 0.000 description 1
• 101000973997 Homo sapiens Nucleosome assembly protein 1-like 4 Proteins 0.000 description 1
• 101000873418 Homo sapiens P-selectin glycoprotein ligand 1 Proteins 0.000 description 1
• 101000910674 Homo sapiens PAT complex subunit CCDC47 Proteins 0.000 description 1
• 101000585555 Homo sapiens PCNA-associated factor Proteins 0.000 description 1
• 101000735213 Homo sapiens Palladin Proteins 0.000 description 1
• 101000904196 Homo sapiens Pancreatic secretory granule membrane major glycoprotein GP2 Proteins 0.000 description 1
• 101000854774 Homo sapiens Pantetheine hydrolase VNN2 Proteins 0.000 description 1
• 101001096050 Homo sapiens Perilipin-2 Proteins 0.000 description 1
• 101001000631 Homo sapiens Peripheral myelin protein 22 Proteins 0.000 description 1
• 101001131990 Homo sapiens Peroxidasin homolog Proteins 0.000 description 1
• 101001041673 Homo sapiens Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Proteins 0.000 description 1
• 101001082860 Homo sapiens Peroxisomal membrane protein 2 Proteins 0.000 description 1
• 101000987493 Homo sapiens Phosphatidylethanolamine-binding protein 1 Proteins 0.000 description 1
• 101000741974 Homo sapiens Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Proteins 0.000 description 1
• 101000604565 Homo sapiens Phosphatidylinositol glycan anchor biosynthesis class U protein Proteins 0.000 description 1
• 101000869517 Homo sapiens Phosphatidylinositol-3-phosphatase SAC1 Proteins 0.000 description 1
• 101000582989 Homo sapiens Phospholipid phosphatase-related protein type 4 Proteins 0.000 description 1
• 101000583156 Homo sapiens Pituitary homeobox 1 Proteins 0.000 description 1
• 101000596046 Homo sapiens Plastin-2 Proteins 0.000 description 1
• 101000596119 Homo sapiens Plastin-3 Proteins 0.000 description 1
• 101001097889 Homo sapiens Platelet-activating factor acetylhydrolase Proteins 0.000 description 1
• 101000609363 Homo sapiens Platelet-activating factor acetylhydrolase IB subunit alpha1 Proteins 0.000 description 1
• 101001096179 Homo sapiens Pleckstrin homology domain-containing family A member 6 Proteins 0.000 description 1
• 101000730611 Homo sapiens Pleckstrin homology domain-containing family G member 5 Proteins 0.000 description 1
• 101000583702 Homo sapiens Pleckstrin homology-like domain family A member 2 Proteins 0.000 description 1
• 101000597240 Homo sapiens Pleckstrin homology-like domain family B member 1 Proteins 0.000 description 1
• 101001126466 Homo sapiens Pleckstrin-2 Proteins 0.000 description 1
• 101000595198 Homo sapiens Podocalyxin Proteins 0.000 description 1
• 101001002235 Homo sapiens Polypeptide N-acetylgalactosaminyltransferase 2 Proteins 0.000 description 1
• 101001049841 Homo sapiens Potassium channel subfamily K member 1 Proteins 0.000 description 1
• 101000610110 Homo sapiens Pre-B-cell leukemia transcription factor 2 Proteins 0.000 description 1
• 101000933173 Homo sapiens Pro-cathepsin H Proteins 0.000 description 1
• 101000901938 Homo sapiens Probable ATP-dependent RNA helicase DHX34 Proteins 0.000 description 1
• 101000864678 Homo sapiens Probable ATP-dependent RNA helicase DHX37 Proteins 0.000 description 1
• 101000983583 Homo sapiens Procathepsin L Proteins 0.000 description 1
• 101000611663 Homo sapiens Prolargin Proteins 0.000 description 1
• 101000931590 Homo sapiens Prostaglandin F2 receptor negative regulator Proteins 0.000 description 1
• 101001135402 Homo sapiens Prostaglandin-H2 D-isomerase Proteins 0.000 description 1
• 101001136954 Homo sapiens Proteasome subunit beta type-7 Proteins 0.000 description 1
• 101000797903 Homo sapiens Protein ALEX Proteins 0.000 description 1
• 101000892061 Homo sapiens Protein CCSMST1 Proteins 0.000 description 1
• 101001048811 Homo sapiens Protein FAM162A Proteins 0.000 description 1
• 101000911541 Homo sapiens Protein FAM214A Proteins 0.000 description 1
• 101000891848 Homo sapiens Protein FAM3D Proteins 0.000 description 1
• 101000911386 Homo sapiens Protein FAM8A1 Proteins 0.000 description 1
• 101001021281 Homo sapiens Protein HEXIM1 Proteins 0.000 description 1
• 101000979599 Homo sapiens Protein NKG7 Proteins 0.000 description 1
• 101000600900 Homo sapiens Protein Njmu-R1 Proteins 0.000 description 1
• 101001074602 Homo sapiens Protein PIMREG Proteins 0.000 description 1
• 101001068628 Homo sapiens Protein PRRC2C Proteins 0.000 description 1
• 101000653788 Homo sapiens Protein S100-A11 Proteins 0.000 description 1
• 101000780643 Homo sapiens Protein argonaute-2 Proteins 0.000 description 1
• 101000971400 Homo sapiens Protein kinase C eta type Proteins 0.000 description 1
• 101001122742 Homo sapiens Protein phosphatase 1 regulatory inhibitor subunit 16B Proteins 0.000 description 1
• 101001122747 Homo sapiens Protein phosphatase 1 regulatory subunit 16A Proteins 0.000 description 1
• 101001122995 Homo sapiens Protein phosphatase 1 regulatory subunit 3C Proteins 0.000 description 1
• 101000831286 Homo sapiens Protein timeless homolog Proteins 0.000 description 1
• 101000822478 Homo sapiens Protein transport protein Sec31B Proteins 0.000 description 1
• 101000630088 Homo sapiens Protein-L-histidine N-pros-methyltransferase Proteins 0.000 description 1
• 101000666171 Homo sapiens Protein-glutamine gamma-glutamyltransferase 2 Proteins 0.000 description 1
• 101000601993 Homo sapiens Protocadherin gamma-C3 Proteins 0.000 description 1
• 101001072245 Homo sapiens Protocadherin-12 Proteins 0.000 description 1
• 101001072227 Homo sapiens Protocadherin-18 Proteins 0.000 description 1
• 101001125901 Homo sapiens Pterin-4-alpha-carbinolamine dehydratase Proteins 0.000 description 1
• 101001086862 Homo sapiens Pulmonary surfactant-associated protein B Proteins 0.000 description 1
• 101000632467 Homo sapiens Pulmonary surfactant-associated protein D Proteins 0.000 description 1
• 101000984932 Homo sapiens Putative butyrophilin subfamily 2 member A3 Proteins 0.000 description 1
• 101001019136 Homo sapiens Putative methyltransferase-like protein 7A Proteins 0.000 description 1
• 101000609335 Homo sapiens Pyrroline-5-carboxylate reductase 1, mitochondrial Proteins 0.000 description 1
• 101000609349 Homo sapiens Pyrroline-5-carboxylate reductase 3 Proteins 0.000 description 1
• 101000743771 Homo sapiens R3H domain-containing protein 2 Proteins 0.000 description 1
• 101001130243 Homo sapiens RAD51-associated protein 1 Proteins 0.000 description 1
• 101100140242 Homo sapiens RDH11 gene Proteins 0.000 description 1
• 101000727821 Homo sapiens RING1 and YY1-binding protein Proteins 0.000 description 1
• 101000743272 Homo sapiens RNA-binding protein 5 Proteins 0.000 description 1
• 101000668140 Homo sapiens RNA-binding protein 8A Proteins 0.000 description 1
• 101001106816 Homo sapiens Rab11 family-interacting protein 2 Proteins 0.000 description 1
• 101000579758 Homo sapiens Raftlin Proteins 0.000 description 1
• 101000712958 Homo sapiens Ras association domain-containing protein 1 Proteins 0.000 description 1
• 101001130298 Homo sapiens Ras-related protein Rab-25 Proteins 0.000 description 1
• 101000584583 Homo sapiens Receptor activity-modifying protein 1 Proteins 0.000 description 1
• 101000584590 Homo sapiens Receptor activity-modifying protein 2 Proteins 0.000 description 1
• 101000584593 Homo sapiens Receptor activity-modifying protein 3 Proteins 0.000 description 1
• 101000606537 Homo sapiens Receptor-type tyrosine-protein phosphatase delta Proteins 0.000 description 1
• 101000591205 Homo sapiens Receptor-type tyrosine-protein phosphatase mu Proteins 0.000 description 1
• 101001092185 Homo sapiens Regulator of cell cycle RGCC Proteins 0.000 description 1
• 101000823237 Homo sapiens Reticulon-1 Proteins 0.000 description 1
• 101000801643 Homo sapiens Retinal-specific phospholipid-transporting ATPase ABCA4 Proteins 0.000 description 1
• 101001100103 Homo sapiens Retinoic acid-induced protein 2 Proteins 0.000 description 1
• 101001100101 Homo sapiens Retinoic acid-induced protein 3 Proteins 0.000 description 1
• 101000665882 Homo sapiens Retinol-binding protein 4 Proteins 0.000 description 1
• 101000856696 Homo sapiens Rho GDP-dissociation inhibitor 2 Proteins 0.000 description 1
• 101000581176 Homo sapiens Rho GTPase-activating protein 18 Proteins 0.000 description 1
• 101001106322 Homo sapiens Rho GTPase-activating protein 7 Proteins 0.000 description 1
• 101000927774 Homo sapiens Rho guanine nucleotide exchange factor 12 Proteins 0.000 description 1
• 101000752249 Homo sapiens Rho guanine nucleotide exchange factor 3 Proteins 0.000 description 1
• 101000927773 Homo sapiens Rho guanine nucleotide exchange factor 9 Proteins 0.000 description 1
• 101000669917 Homo sapiens Rho-associated protein kinase 1 Proteins 0.000 description 1
• 101000709025 Homo sapiens Rho-related BTB domain-containing protein 2 Proteins 0.000 description 1
• 101000581122 Homo sapiens Rho-related GTP-binding protein RhoD Proteins 0.000 description 1
• 101000667821 Homo sapiens Rho-related GTP-binding protein RhoE Proteins 0.000 description 1
• 101000707599 Homo sapiens Rhophilin-1 Proteins 0.000 description 1
• 101000650694 Homo sapiens Roundabout homolog 1 Proteins 0.000 description 1
• 101000650590 Homo sapiens Roundabout homolog 4 Proteins 0.000 description 1
• 101000693728 Homo sapiens S-acyl fatty acid synthase thioesterase, medium chain Proteins 0.000 description 1
• 101000693722 Homo sapiens SAM and SH3 domain-containing protein 3 Proteins 0.000 description 1
• 101000651709 Homo sapiens SCO-spondin Proteins 0.000 description 1
• 101100477442 Homo sapiens SFRP2 gene Proteins 0.000 description 1
• 101000707215 Homo sapiens SH2 domain-containing protein 2A Proteins 0.000 description 1
• 101000688579 Homo sapiens SH3 domain-binding glutamic acid-rich-like protein Proteins 0.000 description 1
• 101000633782 Homo sapiens SLAM family member 8 Proteins 0.000 description 1
• 101100532486 Homo sapiens SLC38A9 gene Proteins 0.000 description 1
• 101100478337 Homo sapiens SRGAP3 gene Proteins 0.000 description 1
• 101000687718 Homo sapiens SWI/SNF complex subunit SMARCC1 Proteins 0.000 description 1
• 101000936917 Homo sapiens Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Proteins 0.000 description 1
• 101000740382 Homo sapiens Sciellin Proteins 0.000 description 1
• 101000864793 Homo sapiens Secreted frizzled-related protein 4 Proteins 0.000 description 1
• 101000873629 Homo sapiens Secretory carrier-associated membrane protein 5 Proteins 0.000 description 1
• 101000685293 Homo sapiens Seizure 6-like protein 2 Proteins 0.000 description 1
• 101000632270 Homo sapiens Semaphorin-3B Proteins 0.000 description 1
• 101001040808 Homo sapiens Serine hydroxymethyltransferase, cytosolic Proteins 0.000 description 1
• 101001041393 Homo sapiens Serine protease HTRA1 Proteins 0.000 description 1
• 101000868090 Homo sapiens Serine-rich coiled-coil domain-containing protein 2 Proteins 0.000 description 1
• 101000674040 Homo sapiens Serine-tRNA ligase, mitochondrial Proteins 0.000 description 1
• 101000987310 Homo sapiens Serine/threonine-protein kinase PAK 2 Proteins 0.000 description 1
• 101000983111 Homo sapiens Serine/threonine-protein kinase PAK 6 Proteins 0.000 description 1
• 101000605835 Homo sapiens Serine/threonine-protein kinase PINK1, mitochondrial Proteins 0.000 description 1
• 101000864057 Homo sapiens Serine/threonine-protein kinase SMG1 Proteins 0.000 description 1
• 101000838578 Homo sapiens Serine/threonine-protein kinase TAO2 Proteins 0.000 description 1
• 101000836394 Homo sapiens Sestrin-1 Proteins 0.000 description 1
• 101000828788 Homo sapiens Signal peptide peptidase-like 3 Proteins 0.000 description 1
• 101000629643 Homo sapiens Signal recognition particle receptor subunit beta Proteins 0.000 description 1
• 101000587455 Homo sapiens Single-stranded DNA-binding protein, mitochondrial Proteins 0.000 description 1
• 101000651890 Homo sapiens Slit homolog 2 protein Proteins 0.000 description 1
• 101000651893 Homo sapiens Slit homolog 3 protein Proteins 0.000 description 1
• 101000713494 Homo sapiens Small nuclear ribonucleoprotein F Proteins 0.000 description 1
• 101000713459 Homo sapiens Small nuclear ribonucleoprotein G Proteins 0.000 description 1
• 101000639972 Homo sapiens Sodium-dependent dopamine transporter Proteins 0.000 description 1
• 101000637813 Homo sapiens Solute carrier family 40 member 1 Proteins 0.000 description 1
• 101000836226 Homo sapiens Solute carrier organic anion transporter family member 2B1 Proteins 0.000 description 1
• 101000618139 Homo sapiens Sperm-associated antigen 6 Proteins 0.000 description 1
• 101000693265 Homo sapiens Sphingosine 1-phosphate receptor 1 Proteins 0.000 description 1
• 101000813777 Homo sapiens Splicing factor ESS-2 homolog Proteins 0.000 description 1
• 101000651299 Homo sapiens Sprouty-related, EVH1 domain-containing protein 2 Proteins 0.000 description 1
• 101000628584 Homo sapiens StAR-related lipid transfer protein 9 Proteins 0.000 description 1
• 101000701446 Homo sapiens Stanniocalcin-2 Proteins 0.000 description 1
• 101000861263 Homo sapiens Steroid 21-hydroxylase Proteins 0.000 description 1
• 101000820460 Homo sapiens Stomatin Proteins 0.000 description 1
• 101000617130 Homo sapiens Stromal cell-derived factor 1 Proteins 0.000 description 1
• 101000708766 Homo sapiens Structural maintenance of chromosomes protein 3 Proteins 0.000 description 1
• 101000630748 Homo sapiens Surfeit locus protein 6 Proteins 0.000 description 1
• 101000648549 Homo sapiens Sushi domain-containing protein 4 Proteins 0.000 description 1
• 101000880098 Homo sapiens Sushi repeat-containing protein SRPX Proteins 0.000 description 1
• 101000820700 Homo sapiens Switch-associated protein 70 Proteins 0.000 description 1
• 101000658851 Homo sapiens Synaptojanin-2-binding protein Proteins 0.000 description 1
• 101000659054 Homo sapiens Synaptopodin Proteins 0.000 description 1
• 101000658110 Homo sapiens Synaptotagmin-like protein 2 Proteins 0.000 description 1
• 101000658114 Homo sapiens Synaptotagmin-like protein 4 Proteins 0.000 description 1
• 101000874179 Homo sapiens Syndecan-1 Proteins 0.000 description 1
• 101000692109 Homo sapiens Syndecan-2 Proteins 0.000 description 1
• 101000706156 Homo sapiens Syntaxin-11 Proteins 0.000 description 1
• 101000648077 Homo sapiens Syntaxin-binding protein 1 Proteins 0.000 description 1
• 101000740523 Homo sapiens Syntenin-1 Proteins 0.000 description 1
• 101000891399 Homo sapiens T-complex protein 11 homolog Proteins 0.000 description 1
• 101000652713 Homo sapiens TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L Proteins 0.000 description 1
• 101000648624 Homo sapiens TATA element modulatory factor Proteins 0.000 description 1
• 101000625818 Homo sapiens TBC1 domain family member 2B Proteins 0.000 description 1
• 101000652484 Homo sapiens TBC1 domain family member 9 Proteins 0.000 description 1
• 101000762938 Homo sapiens TOX high mobility group box family member 4 Proteins 0.000 description 1
• 101000596277 Homo sapiens TSC22 domain family protein 3 Proteins 0.000 description 1
• 101000809875 Homo sapiens TYRO protein tyrosine kinase-binding protein Proteins 0.000 description 1
• 101000798942 Homo sapiens Target of Myb protein 1 Proteins 0.000 description 1
• 101000835541 Homo sapiens Target of Nesh-SH3 Proteins 0.000 description 1
• 101000665590 Homo sapiens Tax1-binding protein 1 Proteins 0.000 description 1
• 101000633632 Homo sapiens Teashirt homolog 3 Proteins 0.000 description 1
• 101000851396 Homo sapiens Tensin-2 Proteins 0.000 description 1
• 101000626153 Homo sapiens Tensin-3 Proteins 0.000 description 1
• 101000800047 Homo sapiens Testican-2 Proteins 0.000 description 1
• 101000772239 Homo sapiens Testis-specific serine/threonine-protein kinase 2 Proteins 0.000 description 1
• 101000759892 Homo sapiens Tetraspanin-13 Proteins 0.000 description 1
• 101000612994 Homo sapiens Tetraspanin-4 Proteins 0.000 description 1
• 101000613001 Homo sapiens Tetraspanin-6 Proteins 0.000 description 1
• 101000612838 Homo sapiens Tetraspanin-7 Proteins 0.000 description 1
• 101000659171 Homo sapiens Tetratricopeptide repeat protein 39A Proteins 0.000 description 1
• 101000763314 Homo sapiens Thrombomodulin Proteins 0.000 description 1
• 101000659879 Homo sapiens Thrombospondin-1 Proteins 0.000 description 1
• 101000831009 Homo sapiens Tigger transposable element-derived protein 5 Proteins 0.000 description 1
• 101000669460 Homo sapiens Toll-like receptor 5 Proteins 0.000 description 1
• 101000662690 Homo sapiens Trafficking protein particle complex subunit 10 Proteins 0.000 description 1
• 101000679485 Homo sapiens Trafficking protein particle complex subunit 6A Proteins 0.000 description 1
• 101000702545 Homo sapiens Transcription activator BRG1 Proteins 0.000 description 1
• 101000800580 Homo sapiens Transcription factor 19 Proteins 0.000 description 1
• 101000800583 Homo sapiens Transcription factor 20 Proteins 0.000 description 1
• 101000800546 Homo sapiens Transcription factor 21 Proteins 0.000 description 1
• 101000732336 Homo sapiens Transcription factor AP-2 gamma Proteins 0.000 description 1
• 101000866336 Homo sapiens Transcription factor E2F5 Proteins 0.000 description 1
• 101000652707 Homo sapiens Transcription initiation factor TFIID subunit 4 Proteins 0.000 description 1
• 101000698001 Homo sapiens Transcription initiation protein SPT3 homolog Proteins 0.000 description 1
• 101000629921 Homo sapiens Translocon-associated protein subunit delta Proteins 0.000 description 1
• 101000938391 Homo sapiens Transmembrane protein Proteins 0.000 description 1
• 101000645402 Homo sapiens Transmembrane protein 163 Proteins 0.000 description 1
• 101000645447 Homo sapiens Transmembrane protein 168 Proteins 0.000 description 1
• 101000714762 Homo sapiens Transmembrane protein 176A Proteins 0.000 description 1
• 101000763433 Homo sapiens Transmembrane protein 204 Proteins 0.000 description 1
• 101000831834 Homo sapiens Transmembrane protein 231 Proteins 0.000 description 1
• 101000662969 Homo sapiens Transmembrane protein 8B Proteins 0.000 description 1
• 101000801742 Homo sapiens Triosephosphate isomerase Proteins 0.000 description 1
• 101000680652 Homo sapiens Tripartite motif-containing protein 14 Proteins 0.000 description 1
• 101000597770 Homo sapiens Tropomodulin-1 Proteins 0.000 description 1
• 101000851357 Homo sapiens Troponin T, slow skeletal muscle Proteins 0.000 description 1
• 101000658481 Homo sapiens Tubulin monoglutamylase TTLL4 Proteins 0.000 description 1
• 101000610794 Homo sapiens Tumor protein D53 Proteins 0.000 description 1
• 101000690425 Homo sapiens Type-1 angiotensin II receptor Proteins 0.000 description 1
• 101000997835 Homo sapiens Tyrosine-protein kinase JAK1 Proteins 0.000 description 1
• 101000997832 Homo sapiens Tyrosine-protein kinase JAK2 Proteins 0.000 description 1
• 101001087418 Homo sapiens Tyrosine-protein phosphatase non-receptor type 12 Proteins 0.000 description 1
• 101000617289 Homo sapiens Tyrosine-protein phosphatase non-receptor type 9 Proteins 0.000 description 1
• 101000760764 Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Proteins 0.000 description 1
• 101000894586 Homo sapiens UPF0687 protein C20orf27 Proteins 0.000 description 1
• 101000868018 Homo sapiens UPF0739 protein C1orf74 Proteins 0.000 description 1
• 101000760229 Homo sapiens Ubiquitin carboxyl-terminal hydrolase 13 Proteins 0.000 description 1
• 101000837581 Homo sapiens Ubiquitin-conjugating enzyme E2 T Proteins 0.000 description 1
• 101000662026 Homo sapiens Ubiquitin-like modifier-activating enzyme 7 Proteins 0.000 description 1
• 101000662278 Homo sapiens Ubiquitin-like protein 3 Proteins 0.000 description 1
• 101001057508 Homo sapiens Ubiquitin-like protein ISG15 Proteins 0.000 description 1
• 101000932776 Homo sapiens Uncharacterized protein C1orf115 Proteins 0.000 description 1
• 101001000122 Homo sapiens Unconventional myosin-Ie Proteins 0.000 description 1
• 101000608672 Homo sapiens Uveal autoantigen with coiled-coil domains and ankyrin repeats Proteins 0.000 description 1
• 101000742596 Homo sapiens Vascular endothelial growth factor C Proteins 0.000 description 1
• 101000851018 Homo sapiens Vascular endothelial growth factor receptor 1 Proteins 0.000 description 1
• 101000860430 Homo sapiens Versican core protein Proteins 0.000 description 1
• 101000631914 Homo sapiens Vesicle-trafficking protein SEC22c Proteins 0.000 description 1
• 101000708573 Homo sapiens Y+L amino acid transporter 2 Proteins 0.000 description 1
• 101100107085 Homo sapiens ZCCHC14 gene Proteins 0.000 description 1
• 101000781866 Homo sapiens Zinc finger CCCH domain-containing protein 7A Proteins 0.000 description 1
• 101000964478 Homo sapiens Zinc finger and BTB domain-containing protein 17 Proteins 0.000 description 1
• 101000976585 Homo sapiens Zinc finger protein 106 Proteins 0.000 description 1
• 101000964725 Homo sapiens Zinc finger protein 184 Proteins 0.000 description 1
• 101000785648 Homo sapiens Zinc finger protein 266 Proteins 0.000 description 1
• 101000915742 Homo sapiens Zinc finger protein ZPR1 Proteins 0.000 description 1
• 101000818867 Homo sapiens Zinc transporter 9 Proteins 0.000 description 1
• 101001094056 Homo sapiens Zinc transporter ZIP11 Proteins 0.000 description 1
• 101000976442 Homo sapiens Zona pellucida sperm-binding protein 3 Proteins 0.000 description 1
• 101000734339 Homo sapiens [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial Proteins 0.000 description 1
• 101000978004 Homo sapiens cAMP-dependent protein kinase inhibitor gamma Proteins 0.000 description 1
• 101000614806 Homo sapiens cAMP-dependent protein kinase type II-beta regulatory subunit Proteins 0.000 description 1
• 101000795753 Homo sapiens mRNA decay activator protein ZFP36 Proteins 0.000 description 1
• 101000838340 Homo sapiens tRNA-dihydrouridine(20) synthase [NAD(P)+]-like Proteins 0.000 description 1
• 102000003839 Human Proteins Human genes 0.000 description 1
• 108090000144 Human Proteins Proteins 0.000 description 1
• 108010013214 Hyaluronan Receptors Proteins 0.000 description 1
• 102000018866 Hyaluronan Receptors Human genes 0.000 description 1
• 102000003918 Hyaluronan Synthases Human genes 0.000 description 1
• 108090000320 Hyaluronan Synthases Proteins 0.000 description 1
• 102100039238 Hyaluronan-binding protein 2 Human genes 0.000 description 1
• 102100039285 Hyaluronidase-2 Human genes 0.000 description 1
• 108090001042 Hydro-Lyases Proteins 0.000 description 1
• 102000004867 Hydro-Lyases Human genes 0.000 description 1
• 102100039356 Hydroxycarboxylic acid receptor 3 Human genes 0.000 description 1
• 206010021143 Hypoxia Diseases 0.000 description 1
• 102100030481 Hypoxia-inducible factor 1-alpha inhibitor Human genes 0.000 description 1
• 108010042653 IgA receptor Proteins 0.000 description 1
• 108010058683 Immobilized Proteins Proteins 0.000 description 1
• 102000009786 Immunoglobulin Constant Regions Human genes 0.000 description 1
• 108010009817 Immunoglobulin Constant Regions Proteins 0.000 description 1
• 108010067060 Immunoglobulin Variable Region Proteins 0.000 description 1
• 102000017727 Immunoglobulin Variable Region Human genes 0.000 description 1
• 102100039348 Immunoglobulin heavy constant gamma 3 Human genes 0.000 description 1
• 102100029572 Immunoglobulin kappa constant Human genes 0.000 description 1
• 102100029616 Immunoglobulin lambda-like polypeptide 1 Human genes 0.000 description 1
• 102100037963 Importin-7 Human genes 0.000 description 1
• 102100026208 Inactive phospholipase C-like protein 2 Human genes 0.000 description 1
• 102100039615 Inactive tyrosine-protein kinase transmembrane receptor ROR1 Human genes 0.000 description 1
• 101000668058 Infectious salmon anemia virus (isolate Atlantic salmon/Norway/810/9/99) RNA-directed RNA polymerase catalytic subunit Proteins 0.000 description 1
• 206010061218 Inflammation Diseases 0.000 description 1
• 102100026818 Inhibin beta E chain Human genes 0.000 description 1
• 102100036724 Innate immunity activator protein Human genes 0.000 description 1
• 102100031533 Inositol 1,4,5-trisphosphate receptor-interacting protein Human genes 0.000 description 1
• 101710150707 Inositol monophosphatase 2 Proteins 0.000 description 1
• 102100031525 Inositol-pentakisphosphate 2-kinase Human genes 0.000 description 1
• 101710126176 Insulin-like growth factor 2 mRNA-binding protein 2 Proteins 0.000 description 1
• 102100037920 Insulin-like growth factor 2 mRNA-binding protein 3 Human genes 0.000 description 1
• 102100022710 Insulin-like growth factor-binding protein 2 Human genes 0.000 description 1
• 102100022708 Insulin-like growth factor-binding protein 3 Human genes 0.000 description 1
• 102100029180 Insulin-like growth factor-binding protein 6 Human genes 0.000 description 1
• 102100023350 Integral membrane protein 2B Human genes 0.000 description 1
• 102100039903 Integrin alpha-9 Human genes 0.000 description 1
• 102100033011 Integrin beta-6 Human genes 0.000 description 1
• 102100033016 Integrin beta-7 Human genes 0.000 description 1
• 108020005210 Integrons Proteins 0.000 description 1
• 101710126866 Intelectin Proteins 0.000 description 1
• 102100023353 Intelectin-1 Human genes 0.000 description 1
• 102100023490 Inter-alpha-trypsin inhibitor heavy chain H1 Human genes 0.000 description 1
• 108010064600 Intercellular Adhesion Molecule-3 Proteins 0.000 description 1
• 102100037871 Intercellular adhesion molecule 3 Human genes 0.000 description 1
• 102100026720 Interferon beta Human genes 0.000 description 1
• 102100036981 Interferon regulatory factor 1 Human genes 0.000 description 1
• 102100038069 Interferon regulatory factor 8 Human genes 0.000 description 1
• 102000000589 Interleukin-1 Human genes 0.000 description 1
• 108010002352 Interleukin-1 Proteins 0.000 description 1
• 108700003107 Interleukin-1 Receptor-Like 1 Proteins 0.000 description 1
• 102100026016 Interleukin-1 receptor type 1 Human genes 0.000 description 1
• 102100026017 Interleukin-1 receptor type 2 Human genes 0.000 description 1
• 102100036706 Interleukin-1 receptor-like 1 Human genes 0.000 description 1
• 102100037795 Interleukin-6 receptor subunit beta Human genes 0.000 description 1
• 102100021592 Interleukin-7 Human genes 0.000 description 1
• 108010002586 Interleukin-7 Proteins 0.000 description 1
• 108010038498 Interleukin-7 Receptors Proteins 0.000 description 1
• 108091092195 Intron Proteins 0.000 description 1
• 102100024434 Iroquois-class homeodomain protein IRX-2 Human genes 0.000 description 1
• 108010044467 Isoenzymes Proteins 0.000 description 1
• 102000004195 Isomerases Human genes 0.000 description 1
• 108090000769 Isomerases Proteins 0.000 description 1
• 102000008986 Janus Human genes 0.000 description 1
• 108050000950 Janus Proteins 0.000 description 1
• 108010040149 Junctional Adhesion Molecule B Proteins 0.000 description 1
• 102100023430 Junctional adhesion molecule B Human genes 0.000 description 1
• 102000017714 KCNJ8 Human genes 0.000 description 1
• 101710024993 KIAA1109 Proteins 0.000 description 1
• 102100021559 KRR1 small subunit processome component homolog Human genes 0.000 description 1
• 108010062228 Karyopherins Proteins 0.000 description 1
• 102000011781 Karyopherins Human genes 0.000 description 1
• 102100022835 Kelch repeat and BTB domain-containing protein 7 Human genes 0.000 description 1
• 102100040487 Keratin, type I cytoskeletal 13 Human genes 0.000 description 1
• 102100040443 Keratin, type I cytoskeletal 15 Human genes 0.000 description 1
• 102100033420 Keratin, type I cytoskeletal 19 Human genes 0.000 description 1
• 102100023129 Keratin, type I cytoskeletal 9 Human genes 0.000 description 1
• 102100028340 Keratin, type II cuticular Hb1 Human genes 0.000 description 1
• 102100037382 Keratin, type II cuticular Hb6 Human genes 0.000 description 1
• 102100025756 Keratin, type II cytoskeletal 5 Human genes 0.000 description 1
• 102100025656 Keratin, type II cytoskeletal 6A Human genes 0.000 description 1
• 108010070557 Keratin-6 Proteins 0.000 description 1
• 102000005706 Keratin-6 Human genes 0.000 description 1
• 108010076876 Keratins Proteins 0.000 description 1
• 102000011782 Keratins Human genes 0.000 description 1
• 102000010638 Kinesin Human genes 0.000 description 1
• 108010063296 Kinesin Proteins 0.000 description 1
• 108050007394 Kinesin-like protein KIF20B Proteins 0.000 description 1
• 102100023424 Kinesin-like protein KIF2C Human genes 0.000 description 1
• 102100021464 Kinetochore scaffold 1 Human genes 0.000 description 1
• 102100020677 Krueppel-like factor 4 Human genes 0.000 description 1
• 102100020684 Krueppel-like factor 9 Human genes 0.000 description 1
• YGJWDZHQJBXRDU-QWRGUYRKSA-N L-4-Hydroxyphenylglycyl-L-arginine Chemical compound N[C@H](C(=O)N[C@@H](CCCN=C(N)N)C(O)=O)c1ccc(O)cc1 YGJWDZHQJBXRDU-QWRGUYRKSA-N 0.000 description 1
• ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 description 1
• KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 1
• 239000005411 L01XE02 - Gefitinib Substances 0.000 description 1
• 102100026460 LIM domain only protein 3 Human genes 0.000 description 1
• 102100035113 LIM domain-binding protein 2 Human genes 0.000 description 1
• 102100022957 LLGL scribble cell polarity complex component 2 Human genes 0.000 description 1
• 241000186660 Lactobacillus Species 0.000 description 1
• 102100030931 Ladinin-1 Human genes 0.000 description 1
• 102100023981 Lamina-associated polypeptide 2, isoform alpha Human genes 0.000 description 1
• 102100022745 Laminin subunit alpha-2 Human genes 0.000 description 1
• 102100022743 Laminin subunit alpha-4 Human genes 0.000 description 1
• 102100027454 Laminin subunit beta-2 Human genes 0.000 description 1
• 102100038204 Large neutral amino acids transporter small subunit 1 Human genes 0.000 description 1
• 102100027017 Latent-transforming growth factor beta-binding protein 2 Human genes 0.000 description 1
• ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 description 1
• 108010006444 Leucine-Rich Repeat Proteins Proteins 0.000 description 1
• 102100031036 Leucine-rich repeat-containing G-protein coupled receptor 5 Human genes 0.000 description 1
• 102100021747 Leukemia inhibitory factor receptor Human genes 0.000 description 1
• 102100025577 Leukocyte immunoglobulin-like receptor subfamily B member 5 Human genes 0.000 description 1
• 102100024221 Leukocyte surface antigen CD53 Human genes 0.000 description 1
• 102100020943 Leukocyte-associated immunoglobulin-like receptor 1 Human genes 0.000 description 1
• 102100032755 Leupaxin Human genes 0.000 description 1
• 102000003960 Ligases Human genes 0.000 description 1
• 102000004895 Lipoproteins Human genes 0.000 description 1
• 108090001030 Lipoproteins Proteins 0.000 description 1
• 108010011449 Long-chain-fatty-acid-CoA ligase Proteins 0.000 description 1
• 102100034318 Long-chain-fatty-acid-CoA ligase 5 Human genes 0.000 description 1
• 108060001084 Luciferase Proteins 0.000 description 1
• 102100032114 Lumican Human genes 0.000 description 1
• 102100034709 Lymphocyte cytosolic protein 2 Human genes 0.000 description 1
• 102100027105 Lymphocyte-specific protein 1 Human genes 0.000 description 1
• KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
• 102100033468 Lysozyme C Human genes 0.000 description 1
• 102100025069 MARVEL domain-containing protein 1 Human genes 0.000 description 1
• 102100022621 MAX gene-associated protein Human genes 0.000 description 1
• 108010018650 MEF2 Transcription Factors Proteins 0.000 description 1
• 102100028123 Macrophage colony-stimulating factor 1 Human genes 0.000 description 1
• 102100028198 Macrophage colony-stimulating factor 1 receptor Human genes 0.000 description 1
• 102100025354 Macrophage mannose receptor 1 Human genes 0.000 description 1
• 102100037791 Macrophage migration inhibitory factor Human genes 0.000 description 1
• 101710167885 Major outer membrane protein P.IB Proteins 0.000 description 1
• GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
• 229920000057 Mannan Polymers 0.000 description 1
• 102100026046 Mannan-binding lectin serine protease 2 Human genes 0.000 description 1
• 102100030612 Mast cell carboxypeptidase A Human genes 0.000 description 1
• 102100024299 Maternal embryonic leucine zipper kinase Human genes 0.000 description 1
• 102000004318 Matrilysin Human genes 0.000 description 1
• 108090000855 Matrilysin Proteins 0.000 description 1
• 108010091175 Matriptase Proteins 0.000 description 1
• 108010016165 Matrix Metalloproteinase 2 Proteins 0.000 description 1
• 102000000424 Matrix Metalloproteinase 2 Human genes 0.000 description 1
• 102100030776 Matrix-remodeling-associated protein 5 Human genes 0.000 description 1
• 102100026174 Mediator of RNA polymerase II transcription subunit 6 Human genes 0.000 description 1
• 102100025077 Melanoma-associated antigen 4 Human genes 0.000 description 1
• 102100025075 Melanoma-associated antigen 6 Human genes 0.000 description 1
• 102100026158 Melanophilin Human genes 0.000 description 1
• 101710158003 Melanophilin Proteins 0.000 description 1
• 102100038465 Membrane-spanning 4-domains subfamily A member 14 Human genes 0.000 description 1
• 102100032512 Membrane-spanning 4-domains subfamily A member 7 Human genes 0.000 description 1
• 102100038557 Membrane-spanning 4-domains subfamily A member 8 Human genes 0.000 description 1
• 101710170181 Metalloproteinase inhibitor Proteins 0.000 description 1
• 102100039364 Metalloproteinase inhibitor 1 Human genes 0.000 description 1
• 102100026262 Metalloproteinase inhibitor 2 Human genes 0.000 description 1
• 102100031603 Metaxin-1 Human genes 0.000 description 1
• 101710101647 Metaxin-1 Proteins 0.000 description 1
• 229920001410 Microfiber Polymers 0.000 description 1
• 102100036103 Microfibril-associated glycoprotein 4 Human genes 0.000 description 1
• 102100031339 Microtubule cross-linking factor 1 Human genes 0.000 description 1
• 102000009664 Microtubule-Associated Proteins Human genes 0.000 description 1
• 108010020004 Microtubule-Associated Proteins Proteins 0.000 description 1
• 208000019695 Migraine disease Diseases 0.000 description 1
• 108091013859 Mimecan Proteins 0.000 description 1
• 102100040273 Mitochondrial glutamate carrier 1 Human genes 0.000 description 1
• 102100026905 Mitochondrial import receptor subunit TOM40 homolog Human genes 0.000 description 1
• 102100031767 Mitochondrial peptide methionine sulfoxide reductase Human genes 0.000 description 1
• 102100038450 Mitochondrial tRNA methylthiotransferase CDK5RAP1 Human genes 0.000 description 1
• 102100037805 Mitogen-activated protein kinase 7 Human genes 0.000 description 1
• 102100030144 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Human genes 0.000 description 1
• 102100027869 Moesin Human genes 0.000 description 1
• 102100025276 Monocarboxylate transporter 4 Human genes 0.000 description 1
• 102000000562 Monocarboxylic Acid Transporters Human genes 0.000 description 1
• 101710204259 Monocarboxylic acid transporter Proteins 0.000 description 1
• 102100035877 Monocyte differentiation antigen CD14 Human genes 0.000 description 1
• 102100034256 Mucin-1 Human genes 0.000 description 1
• 102100034242 Mucin-20 Human genes 0.000 description 1
• 102100021286 Multiple PDZ domain protein Human genes 0.000 description 1
• 101000752700 Mus musculus Abnormal spindle-like microcephaly-associated protein homolog Proteins 0.000 description 1
• 101100042271 Mus musculus Sema3b gene Proteins 0.000 description 1
• 101000661808 Mus musculus Suppressor of tumorigenicity 14 protein homolog Proteins 0.000 description 1
• 101000658113 Mus musculus Synaptotagmin-like protein 4 Proteins 0.000 description 1
• 108010021466 Mutant Proteins Proteins 0.000 description 1
• 102000008300 Mutant Proteins Human genes 0.000 description 1
• 102100034670 Myb-related protein B Human genes 0.000 description 1
• 101710135898 Myc proto-oncogene protein Proteins 0.000 description 1
• 102100038895 Myc proto-oncogene protein Human genes 0.000 description 1
• 102100039229 Myocyte-specific enhancer factor 2C Human genes 0.000 description 1
• 108091005975 Myofilaments Proteins 0.000 description 1
• 102100031787 Myosin regulatory light polypeptide 9 Human genes 0.000 description 1
• OVRNDRQMDRJTHS-KEWYIRBNSA-N N-acetyl-D-galactosamine Chemical compound CC(=O)N[C@H]1C(O)O[C@H](CO)[C@H](O)[C@@H]1O OVRNDRQMDRJTHS-KEWYIRBNSA-N 0.000 description 1
• 102100035629 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 Human genes 0.000 description 1
• 102100038360 N-acylethanolamine-hydrolyzing acid amidase Human genes 0.000 description 1
• 102100023648 N-chimaerin Human genes 0.000 description 1
• ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 description 1
• CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 description 1
• HZNOAQPAYUWRGU-UHFFFAOYSA-N N.N.[Ca+2].[Ca+2] Chemical compound N.N.[Ca+2].[Ca+2] HZNOAQPAYUWRGU-UHFFFAOYSA-N 0.000 description 1
• 102100036777 NADPH:adrenodoxin oxidoreductase, mitochondrial Human genes 0.000 description 1
• 108010018525 NFATC Transcription Factors Proteins 0.000 description 1
• 102000002673 NFATC Transcription Factors Human genes 0.000 description 1
• 101150065592 NME2 gene Proteins 0.000 description 1
• 102000002452 NPR3 Human genes 0.000 description 1
• 101150066297 NPR3 gene Proteins 0.000 description 1
• 108091008758 NR0A5 Proteins 0.000 description 1
• 108020002076 NR2 subfamily Proteins 0.000 description 1
• 102000038100 NR2 subfamily Human genes 0.000 description 1
• 108020002144 NR4 subfamily Proteins 0.000 description 1
• 102100029448 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 Human genes 0.000 description 1
• 102100035486 Nectin-4 Human genes 0.000 description 1
• 102000048850 Neoplasm Genes Human genes 0.000 description 1
• 108700019961 Neoplasm Genes Proteins 0.000 description 1
• 108010088225 Nestin Proteins 0.000 description 1
• 102100028749 Neuritin Human genes 0.000 description 1
• 101710189685 Neuritin Proteins 0.000 description 1
• 206010029260 Neuroblastoma Diseases 0.000 description 1
• 102100038819 Neuromedin-B Human genes 0.000 description 1
• 102100038813 Neuromedin-U Human genes 0.000 description 1
• 102100031225 Neuron navigator 1 Human genes 0.000 description 1
• 102100021852 Neuronal cell adhesion molecule Human genes 0.000 description 1
• 102100033800 Neuronal membrane glycoprotein M6-b Human genes 0.000 description 1
• 102100038436 Neuronal pentraxin-1 Human genes 0.000 description 1
• 102100021878 Neuronal pentraxin-2 Human genes 0.000 description 1
• 101100344969 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) med-6 gene Proteins 0.000 description 1
• 108010064862 Nicotinamide phosphoribosyltransferase Proteins 0.000 description 1
• 102100033223 Nicotinamide phosphoribosyltransferase Human genes 0.000 description 1
• 102100034450 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 Human genes 0.000 description 1
• 102100023121 Ninein Human genes 0.000 description 1
• 102100027889 Ninjurin-2 Human genes 0.000 description 1
• 239000000020 Nitrocellulose Substances 0.000 description 1
• 108010015847 Non-Receptor Type 1 Protein Tyrosine Phosphatase Proteins 0.000 description 1
• 102000002072 Non-Receptor Type 1 Protein Tyrosine Phosphatase Human genes 0.000 description 1
• 102100035404 Nuclear RNA export factor 3 Human genes 0.000 description 1
• 102100035397 Nuclear factor related to kappa-B-binding protein Human genes 0.000 description 1
• 108020005497 Nuclear hormone receptor Proteins 0.000 description 1
• 102100022679 Nuclear receptor subfamily 4 group A member 1 Human genes 0.000 description 1
• 102100022676 Nuclear receptor subfamily 4 group A member 2 Human genes 0.000 description 1
• 101710163270 Nuclease Proteins 0.000 description 1
• 102100030991 Nucleolar and spindle-associated protein 1 Human genes 0.000 description 1
• 102100023252 Nucleoside diphosphate kinase A Human genes 0.000 description 1
• 102100022396 Nucleosome assembly protein 1-like 4 Human genes 0.000 description 1
• 108010047956 Nucleosomes Proteins 0.000 description 1
• BZQFBWGGLXLEPQ-UWTATZPHSA-N O-phospho-D-serine Chemical compound OC(=O)[C@H](N)COP(O)(O)=O BZQFBWGGLXLEPQ-UWTATZPHSA-N 0.000 description 1
• 241000207836 Olea <angiosperm> Species 0.000 description 1
• 108010020361 Oncogene Protein gp140(v-fms) Proteins 0.000 description 1
• 108010054076 Oncogene Proteins v-myb Proteins 0.000 description 1
• 102000016978 Orphan receptors Human genes 0.000 description 1
• 108070000031 Orphan receptors Proteins 0.000 description 1
• 108010081689 Osteopontin Proteins 0.000 description 1
• 102000004264 Osteopontin Human genes 0.000 description 1
• 206010033128 Ovarian cancer Diseases 0.000 description 1
• 206010061535 Ovarian neoplasm Diseases 0.000 description 1
• 102100034925 P-selectin glycoprotein ligand 1 Human genes 0.000 description 1
• 102100024093 PAT complex subunit CCDC47 Human genes 0.000 description 1
• 229910019142 PO4 Inorganic materials 0.000 description 1
• 108060006580 PRAME Proteins 0.000 description 1
• 102000036673 PRAME Human genes 0.000 description 1
• 108010011536 PTEN Phosphohydrolase Proteins 0.000 description 1
• 102100035031 Palladin Human genes 0.000 description 1
• 241000282579 Pan Species 0.000 description 1
• 244000131316 Panax pseudoginseng Species 0.000 description 1
• 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
• 235000003140 Panax quinquefolius Nutrition 0.000 description 1
• 206010061902 Pancreatic neoplasm Diseases 0.000 description 1
• 102100024019 Pancreatic secretory granule membrane major glycoprotein GP2 Human genes 0.000 description 1
• 102100020748 Pantetheine hydrolase VNN2 Human genes 0.000 description 1
• 241000282520 Papio Species 0.000 description 1
• 241001494479 Pecora Species 0.000 description 1
• 108010044843 Peptide Initiation Factors Proteins 0.000 description 1
• 102000005877 Peptide Initiation Factors Human genes 0.000 description 1
• 108010067902 Peptide Library Proteins 0.000 description 1
• 102100037026 Peptidyl-prolyl cis-trans isomerase FKBP5 Human genes 0.000 description 1
• 102100037896 Perilipin-2 Human genes 0.000 description 1
• 102100034601 Peroxidasin homolog Human genes 0.000 description 1
• 102100021404 Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Human genes 0.000 description 1
• 102100030564 Peroxisomal membrane protein 2 Human genes 0.000 description 1
• 102100028489 Phosphatidylethanolamine-binding protein 1 Human genes 0.000 description 1
• 102100032543 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Human genes 0.000 description 1
• 102100038634 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Human genes 0.000 description 1
• 108090000430 Phosphatidylinositol 3-kinases Proteins 0.000 description 1
• 102000003993 Phosphatidylinositol 3-kinases Human genes 0.000 description 1
• 102100032286 Phosphatidylinositol-3-phosphatase SAC1 Human genes 0.000 description 1
• 108010010677 Phosphodiesterase I Proteins 0.000 description 1
• 102000009097 Phosphorylases Human genes 0.000 description 1
• 108010073135 Phosphorylases Proteins 0.000 description 1
• 102100021768 Phosphoserine aminotransferase Human genes 0.000 description 1
• 102100030345 Pituitary homeobox 1 Human genes 0.000 description 1
• 102000016249 Plakophilin-3 Human genes 0.000 description 1
• 108010057275 Plakophilins Proteins 0.000 description 1
• 102100029743 Plasma membrane calcium-transporting ATPase 4 Human genes 0.000 description 1
• 108050003586 Plasma membrane calcium-transporting ATPase 4 Proteins 0.000 description 1
• 102100035220 Plastin-3 Human genes 0.000 description 1
• 102100037518 Platelet-activating factor acetylhydrolase Human genes 0.000 description 1
• 102100039446 Platelet-activating factor acetylhydrolase IB subunit alpha1 Human genes 0.000 description 1
• 102100030264 Pleckstrin Human genes 0.000 description 1
• 102100037869 Pleckstrin homology domain-containing family A member 6 Human genes 0.000 description 1
• 102100032589 Pleckstrin homology domain-containing family G member 5 Human genes 0.000 description 1
• 102100030926 Pleckstrin homology-like domain family A member 2 Human genes 0.000 description 1
• 102100035150 Pleckstrin homology-like domain family B member 1 Human genes 0.000 description 1
• 102100030470 Pleckstrin-2 Human genes 0.000 description 1
• 206010035664 Pneumonia Diseases 0.000 description 1
• 102100036031 Podocalyxin Human genes 0.000 description 1
• 108010000598 Polycomb Repressive Complex 1 Proteins 0.000 description 1
• 102100020950 Polypeptide N-acetylgalactosaminyltransferase 2 Human genes 0.000 description 1
• 102100023242 Potassium channel subfamily K member 1 Human genes 0.000 description 1
• 102100023202 Potassium channel subfamily K member 5 Human genes 0.000 description 1
• 102100040168 Pre-B-cell leukemia transcription factor 2 Human genes 0.000 description 1
• 241000288906 Primates Species 0.000 description 1
• 102100025974 Pro-cathepsin H Human genes 0.000 description 1
• 102100030093 Probable ATP-dependent RNA helicase DHX37 Human genes 0.000 description 1
• 102100031145 Probable low affinity copper uptake protein 2 Human genes 0.000 description 1
• 102100026534 Procathepsin L Human genes 0.000 description 1
• 208000028872 Progressive muscular dystrophy Diseases 0.000 description 1
• 102100040659 Prolargin Human genes 0.000 description 1
• 102100021923 Prolow-density lipoprotein receptor-related protein 1 Human genes 0.000 description 1
• 102100034014 Prolyl 3-hydroxylase 3 Human genes 0.000 description 1
• 102100036197 Prosaposin Human genes 0.000 description 1
• 101710116300 Prostaglandin F2 receptor negative regulator Proteins 0.000 description 1
• 108010065942 Prostaglandin-F synthase Proteins 0.000 description 1
• 102100033279 Prostaglandin-H2 D-isomerase Human genes 0.000 description 1
• 229940124158 Protease/peptidase inhibitor Drugs 0.000 description 1
• 101800004937 Protein C Proteins 0.000 description 1
• 102100024949 Protein CBFA2T2 Human genes 0.000 description 1
• 102100040781 Protein CCSMST1 Human genes 0.000 description 1
• 101710188053 Protein D Proteins 0.000 description 1
• 102100023788 Protein FAM162A Human genes 0.000 description 1
• 102100026957 Protein FAM214A Human genes 0.000 description 1
• 102100040821 Protein FAM3D Human genes 0.000 description 1
• 102100026751 Protein FAM8A1 Human genes 0.000 description 1
• 102100023370 Protein NKG7 Human genes 0.000 description 1
• 102100037347 Protein Njmu-R1 Human genes 0.000 description 1
• 102100036258 Protein PIMREG Human genes 0.000 description 1
• 102100033952 Protein PRRC2C Human genes 0.000 description 1
• 101710110945 Protein S100-A11 Proteins 0.000 description 1
• 102100034207 Protein argonaute-2 Human genes 0.000 description 1
• 101710093047 Protein grainyhead Proteins 0.000 description 1
• 102100021556 Protein kinase C eta type Human genes 0.000 description 1
• 102100028740 Protein phosphatase 1 regulatory inhibitor subunit 16B Human genes 0.000 description 1
• 102100028722 Protein phosphatase 1 regulatory subunit 16A Human genes 0.000 description 1
• 102100028506 Protein phosphatase 1 regulatory subunit 3C Human genes 0.000 description 1
• 102100033947 Protein regulator of cytokinesis 1 Human genes 0.000 description 1
• 102100022485 Protein transport protein Sec31B Human genes 0.000 description 1
• 102100026221 Protein-L-histidine N-pros-methyltransferase Human genes 0.000 description 1
• 102100038095 Protein-glutamine gamma-glutamyltransferase 2 Human genes 0.000 description 1
• 102000016611 Proteoglycans Human genes 0.000 description 1
• 108010067787 Proteoglycans Proteins 0.000 description 1
• 102100037560 Protocadherin gamma-C3 Human genes 0.000 description 1
• 102100036385 Protocadherin-12 Human genes 0.000 description 1
• 102100036397 Protocadherin-18 Human genes 0.000 description 1
• 235000006040 Prunus persica var persica Nutrition 0.000 description 1
• 102100029333 Pterin-4-alpha-carbinolamine dehydratase Human genes 0.000 description 1
• 102100032617 Pulmonary surfactant-associated protein B Human genes 0.000 description 1
• 102100027845 Pulmonary surfactant-associated protein D Human genes 0.000 description 1
• 241000382353 Pupa Species 0.000 description 1
• 101710180958 Putative aminoacrylate hydrolase RutD Proteins 0.000 description 1
• 102100027141 Putative butyrophilin subfamily 2 member A3 Human genes 0.000 description 1
• 102100034758 Putative methyltransferase-like protein 7A Human genes 0.000 description 1
• 102100039407 Pyrroline-5-carboxylate reductase 1, mitochondrial Human genes 0.000 description 1
• 102100039448 Pyrroline-5-carboxylate reductase 3 Human genes 0.000 description 1
• 102100038384 R3H domain-containing protein 2 Human genes 0.000 description 1
• 102100031535 RAD51-associated protein 1 Human genes 0.000 description 1
• 101150022282 RCAN2 gene Proteins 0.000 description 1
• 101710178916 RING-box protein 1 Proteins 0.000 description 1
• 102100029760 RING1 and YY1-binding protein Human genes 0.000 description 1
• 102100025902 RNA-binding protein 3 Human genes 0.000 description 1
• 101710133263 RNA-binding protein 3 Proteins 0.000 description 1
• 102100038152 RNA-binding protein 5 Human genes 0.000 description 1
• 102100039691 RNA-binding protein 8A Human genes 0.000 description 1
• 102100021314 Rab11 family-interacting protein 2 Human genes 0.000 description 1
• 102000002490 Rad51 Recombinase Human genes 0.000 description 1
• 108010068097 Rad51 Recombinase Proteins 0.000 description 1
• 102100023320 Ral guanine nucleotide dissociation stimulator Human genes 0.000 description 1
• 108050008437 Ral guanine nucleotide dissociation stimulator Proteins 0.000 description 1
• 102100033975 Ran-binding protein 3 Human genes 0.000 description 1
• 101150020444 Ranbp3 gene Proteins 0.000 description 1
• 102100033243 Ras association domain-containing protein 1 Human genes 0.000 description 1
• 102100031528 Ras-related protein Rab-25 Human genes 0.000 description 1
• 241000700157 Rattus norvegicus Species 0.000 description 1
• 101100454869 Rattus norvegicus Lhx5 gene Proteins 0.000 description 1
• 102000001218 Rec A Recombinases Human genes 0.000 description 1
• 108010055016 Rec A Recombinases Proteins 0.000 description 1
• 102100030697 Receptor activity-modifying protein 1 Human genes 0.000 description 1
• 102100030696 Receptor activity-modifying protein 2 Human genes 0.000 description 1
• 102100030711 Receptor activity-modifying protein 3 Human genes 0.000 description 1
• 102100039666 Receptor-type tyrosine-protein phosphatase delta Human genes 0.000 description 1
• 102100034090 Receptor-type tyrosine-protein phosphatase mu Human genes 0.000 description 1
• 208000015634 Rectal Neoplasms Diseases 0.000 description 1
• 102100033796 Regulation of nuclear pre-mRNA domain-containing protein 1B Human genes 0.000 description 1
• 102100021269 Regulator of G-protein signaling 1 Human genes 0.000 description 1
• 101710140408 Regulator of G-protein signaling 1 Proteins 0.000 description 1
• 102100037421 Regulator of G-protein signaling 5 Human genes 0.000 description 1
• 101710140403 Regulator of G-protein signaling 5 Proteins 0.000 description 1
• 102100035542 Regulator of cell cycle RGCC Human genes 0.000 description 1
• 101710132893 Resolvase Proteins 0.000 description 1
• 102100022647 Reticulon-1 Human genes 0.000 description 1
• 201000007737 Retinal degeneration Diseases 0.000 description 1
• 102100033617 Retinal-specific phospholipid-transporting ATPase ABCA4 Human genes 0.000 description 1
• 102100038452 Retinoic acid-induced protein 2 Human genes 0.000 description 1
• 102100038453 Retinoic acid-induced protein 3 Human genes 0.000 description 1
• 102100023916 Retinol dehydrogenase 11 Human genes 0.000 description 1
• 102100038246 Retinol-binding protein 4 Human genes 0.000 description 1
• 241000271570 Rhea americana Species 0.000 description 1
• 102100025622 Rho GDP-dissociation inhibitor 2 Human genes 0.000 description 1
• 102100027655 Rho GTPase-activating protein 18 Human genes 0.000 description 1
• 102100021446 Rho GTPase-activating protein 7 Human genes 0.000 description 1
• 102100033193 Rho guanine nucleotide exchange factor 12 Human genes 0.000 description 1
• 102100021689 Rho guanine nucleotide exchange factor 3 Human genes 0.000 description 1
• 102100033221 Rho guanine nucleotide exchange factor 9 Human genes 0.000 description 1
• 102100039313 Rho-associated protein kinase 1 Human genes 0.000 description 1
• 102100032658 Rho-related BTB domain-containing protein 2 Human genes 0.000 description 1
• 102100039640 Rho-related GTP-binding protein RhoE Human genes 0.000 description 1
• 102100031363 Rhophilin-1 Human genes 0.000 description 1
• 102100027702 Roundabout homolog 1 Human genes 0.000 description 1
• 102100027701 Roundabout homolog 4 Human genes 0.000 description 1
• 102100025541 S-acyl fatty acid synthase thioesterase, medium chain Human genes 0.000 description 1
• 102100025544 SAM and SH3 domain-containing protein 3 Human genes 0.000 description 1
• 102100031779 SH2 domain-containing protein 2A Human genes 0.000 description 1
• 102100024243 SH3 domain-binding glutamic acid-rich-like protein Human genes 0.000 description 1
• 102100029214 SLAM family member 8 Human genes 0.000 description 1
• 108091006410 SLC25A10 Proteins 0.000 description 1
• 108091006529 SLC28A2 Proteins 0.000 description 1
• 108091006296 SLC2A1 Proteins 0.000 description 1
• 108091006298 SLC2A3 Proteins 0.000 description 1
• 108091006567 SLC31A2 Proteins 0.000 description 1
• 102000005038 SLC6A4 Human genes 0.000 description 1
• 102000005041 SLC6A8 Human genes 0.000 description 1
• 108091006248 SLC7 Cationic Amino Acid Transporter Proteins 0.000 description 1
• 108091006229 SLC7A1 Proteins 0.000 description 1
• 108091006232 SLC7A5 Proteins 0.000 description 1
• 102100037375 SLIT-ROBO Rho GTPase-activating protein 3 Human genes 0.000 description 1
• 108700022176 SOS1 Proteins 0.000 description 1
• 102100024793 SWI/SNF complex subunit SMARCC1 Human genes 0.000 description 1
• 101000741943 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) Serine/threonine-protein phosphatase 2B catalytic subunit A1 Proteins 0.000 description 1
• 102100036546 Salivary acidic proline-rich phosphoprotein 1/2 Human genes 0.000 description 1
• 241000607142 Salmonella Species 0.000 description 1
• 101800001700 Saposin-D Proteins 0.000 description 1
• 206010039491 Sarcoma Diseases 0.000 description 1
• 102100027733 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Human genes 0.000 description 1
• 241000235347 Schizosaccharomyces pombe Species 0.000 description 1
• 101100010298 Schizosaccharomyces pombe (strain 972 / ATCC 24843) pol2 gene Proteins 0.000 description 1
• 102100037235 Sciellin Human genes 0.000 description 1
• 240000004534 Scutellaria baicalensis Species 0.000 description 1
• 235000017089 Scutellaria baicalensis Nutrition 0.000 description 1
• 102100030054 Secreted frizzled-related protein 2 Human genes 0.000 description 1
• 102100030052 Secreted frizzled-related protein 4 Human genes 0.000 description 1
• 102100035894 Secretory carrier-associated membrane protein 5 Human genes 0.000 description 1
• 108090000184 Selectins Proteins 0.000 description 1
• 102000003800 Selectins Human genes 0.000 description 1
• 102100023843 Selenoprotein P Human genes 0.000 description 1
• 102100027979 Semaphorin-3B Human genes 0.000 description 1
• 206010040007 Sense of oppression Diseases 0.000 description 1
• 102100021225 Serine hydroxymethyltransferase, cytosolic Human genes 0.000 description 1
• 102100034606 Serine hydroxymethyltransferase, mitochondrial Human genes 0.000 description 1
• 102100032895 Serine-rich coiled-coil domain-containing protein 2 Human genes 0.000 description 1
• 102100040597 Serine-tRNA ligase, mitochondrial Human genes 0.000 description 1
• 102100026840 Serine/threonine-protein kinase PAK 6 Human genes 0.000 description 1
• 102100038376 Serine/threonine-protein kinase PINK1, mitochondrial Human genes 0.000 description 1
• 101710085356 Serine/threonine-protein kinase SMG1 Proteins 0.000 description 1
• 102100028949 Serine/threonine-protein kinase TAO2 Human genes 0.000 description 1
• 108010012996 Serotonin Plasma Membrane Transport Proteins Proteins 0.000 description 1
• 102100022056 Serum response factor Human genes 0.000 description 1
• 102100027288 Sestrin-1 Human genes 0.000 description 1
• 102100037576 Sestrin-2 Human genes 0.000 description 1
• 101710142587 Short-chain dehydrogenase/reductase Proteins 0.000 description 1
• 101710111748 Signal peptide peptidase-like 3 Proteins 0.000 description 1
• 102100026904 Signal recognition particle receptor subunit beta Human genes 0.000 description 1
• 241000700584 Simplexvirus Species 0.000 description 1
• 102100029719 Single-stranded DNA-binding protein, mitochondrial Human genes 0.000 description 1
• 102100027339 Slit homolog 3 protein Human genes 0.000 description 1
• 102100036768 Small nuclear ribonucleoprotein G Human genes 0.000 description 1
• FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
• 102100021479 Sodium-coupled neutral amino acid transporter 9 Human genes 0.000 description 1
• 102100021541 Sodium/nucleoside cotransporter 2 Human genes 0.000 description 1
• 102100023536 Solute carrier family 2, facilitated glucose transporter member 1 Human genes 0.000 description 1
• 102100032008 Solute carrier family 40 member 1 Human genes 0.000 description 1
• 102100027264 Solute carrier organic anion transporter family member 2B1 Human genes 0.000 description 1
• 102100021909 Sperm-associated antigen 6 Human genes 0.000 description 1
• 102100025750 Sphingosine 1-phosphate receptor 1 Human genes 0.000 description 1
• 241000251131 Sphyrna Species 0.000 description 1
• 102100039575 Splicing factor ESS-2 homolog Human genes 0.000 description 1
• 102100027650 Sprouty-related, EVH1 domain-containing protein 2 Human genes 0.000 description 1
• 102100026756 StAR-related lipid transfer protein 9 Human genes 0.000 description 1
• 102100030510 Stanniocalcin-2 Human genes 0.000 description 1
• 102100038035 Starch-binding domain-containing protein 1 Human genes 0.000 description 1
• 102100027545 Steroid 21-hydroxylase Human genes 0.000 description 1
• 101000720079 Stichodactyla helianthus DELTA-stichotoxin-She4a Proteins 0.000 description 1
• 108700037714 Stomatin Proteins 0.000 description 1
• 102100021669 Stromal cell-derived factor 1 Human genes 0.000 description 1
• 101710117918 Structural maintenance of chromosomes protein 3 Proteins 0.000 description 1
• 229930006000 Sucrose Natural products 0.000 description 1
• CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
• 241000282887 Suidae Species 0.000 description 1
• NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
• UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 description 1
• 102100026318 Surfeit locus protein 6 Human genes 0.000 description 1
• 108010002687 Survivin Proteins 0.000 description 1
• 102100028860 Sushi domain-containing protein 4 Human genes 0.000 description 1
• 102100021701 Switch-associated protein 70 Human genes 0.000 description 1
• 102100035581 Synaptojanin-2-binding protein Human genes 0.000 description 1
• 102100035604 Synaptopodin Human genes 0.000 description 1
• 102100035007 Synaptotagmin-like protein 2 Human genes 0.000 description 1
• 102100035002 Synaptotagmin-like protein 4 Human genes 0.000 description 1
• 102100035721 Syndecan-1 Human genes 0.000 description 1
• 108090000054 Syndecan-2 Proteins 0.000 description 1
• 102000003711 Syndecan-2 Human genes 0.000 description 1
• 102100026087 Syndecan-2 Human genes 0.000 description 1
• 102100031115 Syntaxin-11 Human genes 0.000 description 1
• 102100024174 Syntaxin-7 Human genes 0.000 description 1
• 102100025293 Syntaxin-binding protein 1 Human genes 0.000 description 1
• 102100037219 Syntenin-1 Human genes 0.000 description 1
• 108010088184 T Cell Transcription Factor 1 Proteins 0.000 description 1
• 230000006044 T cell activation Effects 0.000 description 1
• 230000024932 T cell mediated immunity Effects 0.000 description 1
• 108700042075 T-Cell Receptor Genes Proteins 0.000 description 1
• 208000000389 T-cell leukemia Diseases 0.000 description 1
• 208000028530 T-cell lymphoblastic leukemia/lymphoma Diseases 0.000 description 1
• 102100030838 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L Human genes 0.000 description 1
• 102100028866 TATA element modulatory factor Human genes 0.000 description 1
• 102100024766 TBC1 domain family member 2B Human genes 0.000 description 1
• 102100030306 TBC1 domain family member 9 Human genes 0.000 description 1
• 108090000925 TNF receptor-associated factor 2 Proteins 0.000 description 1
• 102100026749 TOX high mobility group box family member 4 Human genes 0.000 description 1
• 102100034779 TRAF family member-associated NF-kappa-B activator Human genes 0.000 description 1
• 102100035260 TSC22 domain family protein 3 Human genes 0.000 description 1
• 101150116444 TST gene Proteins 0.000 description 1
• 102100038717 TYRO protein tyrosine kinase-binding protein Human genes 0.000 description 1
• 102100034024 Target of Myb protein 1 Human genes 0.000 description 1
• 102100026544 Target of Nesh-SH3 Human genes 0.000 description 1
• 102100038193 Tax1-binding protein 1 Human genes 0.000 description 1
• 102100029222 Teashirt homolog 3 Human genes 0.000 description 1
• 102100036852 Tensin-2 Human genes 0.000 description 1
• 102100024548 Tensin-3 Human genes 0.000 description 1
• 102100033371 Testican-2 Human genes 0.000 description 1
• 102100029355 Testis-specific serine/threonine-protein kinase 2 Human genes 0.000 description 1
• 241000270708 Testudinidae Species 0.000 description 1
• 102100024554 Tetranectin Human genes 0.000 description 1
• 102100024996 Tetraspanin-13 Human genes 0.000 description 1
• 102100040871 Tetraspanin-4 Human genes 0.000 description 1
• 102100040869 Tetraspanin-6 Human genes 0.000 description 1
• 102100040952 Tetraspanin-7 Human genes 0.000 description 1
• 102100036124 Tetratricopeptide repeat protein 39A Human genes 0.000 description 1
• JZRWCGZRTZMZEH-UHFFFAOYSA-N Thiamine Natural products CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 description 1
• 102100036407 Thioredoxin Human genes 0.000 description 1
• 108090000190 Thrombin Proteins 0.000 description 1
• 102000002938 Thrombospondin Human genes 0.000 description 1
• 108060008245 Thrombospondin Proteins 0.000 description 1
• 102100036034 Thrombospondin-1 Human genes 0.000 description 1
• 108010057966 Thyroid Nuclear Factor 1 Proteins 0.000 description 1
• 102100024831 Tigger transposable element-derived protein 5 Human genes 0.000 description 1
• 102000005406 Tissue Inhibitor of Metalloproteinase-3 Human genes 0.000 description 1
• 108010031429 Tissue Inhibitor of Metalloproteinase-3 Proteins 0.000 description 1
• 102000019346 Tob2 Human genes 0.000 description 1
• 108050006879 Tob2 Proteins 0.000 description 1
• 101710183280 Topoisomerase Proteins 0.000 description 1
• 101710120037 Toxin CcdB Proteins 0.000 description 1
• 102100037456 Trafficking protein particle complex subunit 10 Human genes 0.000 description 1
• 102100022607 Trafficking protein particle complex subunit 6A Human genes 0.000 description 1
• 102100031027 Transcription activator BRG1 Human genes 0.000 description 1
• 102000040945 Transcription factor Human genes 0.000 description 1
• 108091023040 Transcription factor Proteins 0.000 description 1
• 102100033159 Transcription factor 19 Human genes 0.000 description 1
• 102100033142 Transcription factor 20 Human genes 0.000 description 1
• 102100033121 Transcription factor 21 Human genes 0.000 description 1
• 102100030627 Transcription factor 7 Human genes 0.000 description 1
• 102000004893 Transcription factor AP-2 Human genes 0.000 description 1
• 108090001039 Transcription factor AP-2 Proteins 0.000 description 1
• 102100033345 Transcription factor AP-2 gamma Human genes 0.000 description 1
• 102100030833 Transcription initiation factor TFIID subunit 4 Human genes 0.000 description 1
• 102100027912 Transcription initiation protein SPT3 homolog Human genes 0.000 description 1
• 101710150448 Transcriptional regulator Myc Proteins 0.000 description 1
• 102000004357 Transferases Human genes 0.000 description 1
• 108090000992 Transferases Proteins 0.000 description 1
• 108010082684 Transforming Growth Factor-beta Type II Receptor Proteins 0.000 description 1
• 102000004060 Transforming Growth Factor-beta Type II Receptor Human genes 0.000 description 1
• 102100025946 Transforming growth factor beta activator LRRC32 Human genes 0.000 description 1
• 101710169732 Transforming growth factor beta activator LRRC32 Proteins 0.000 description 1
• 102100026226 Translocon-associated protein subunit delta Human genes 0.000 description 1
• 102100025764 Transmembrane protein 163 Human genes 0.000 description 1
• 102100025712 Transmembrane protein 168 Human genes 0.000 description 1
• 102100036380 Transmembrane protein 176A Human genes 0.000 description 1
• 102100027027 Transmembrane protein 204 Human genes 0.000 description 1
• 102100024183 Transmembrane protein 231 Human genes 0.000 description 1
• 102100028842 Transmembrane protein 72 Human genes 0.000 description 1
• 102100037634 Transmembrane protein 8B Human genes 0.000 description 1
• 102100025378 Transmembrane protein KIAA1109 Human genes 0.000 description 1
• 108010078184 Trefoil Factor-3 Proteins 0.000 description 1
• 102100039145 Trefoil factor 3 Human genes 0.000 description 1
• 101710085765 Tricarboxylate transport protein Proteins 0.000 description 1
• 102100033598 Triosephosphate isomerase Human genes 0.000 description 1
• 102100022350 Tripartite motif-containing protein 14 Human genes 0.000 description 1
• 235000021307 Triticum Nutrition 0.000 description 1
• 244000098338 Triticum aestivum Species 0.000 description 1
• YZCKVEUIGOORGS-NJFSPNSNSA-N Tritium Chemical group [3H] YZCKVEUIGOORGS-NJFSPNSNSA-N 0.000 description 1
• 102100035291 Tropomodulin-1 Human genes 0.000 description 1
• 102000013394 Troponin I Human genes 0.000 description 1
• 108010065729 Troponin I Proteins 0.000 description 1
• 102100036860 Troponin T, slow skeletal muscle Human genes 0.000 description 1
• 102000009322 Tudor domains Human genes 0.000 description 1
• 108050000178 Tudor domains Proteins 0.000 description 1
• 108010040002 Tumor Suppressor Proteins Proteins 0.000 description 1
• 102000001742 Tumor Suppressor Proteins Human genes 0.000 description 1
• 102100027881 Tumor protein 63 Human genes 0.000 description 1
• 101710140697 Tumor protein 63 Proteins 0.000 description 1
• 102100040362 Tumor protein D53 Human genes 0.000 description 1
• 102000011017 Type 4 Cyclic Nucleotide Phosphodiesterases Human genes 0.000 description 1
• 108010037584 Type 4 Cyclic Nucleotide Phosphodiesterases Proteins 0.000 description 1
• 102100026803 Type-1 angiotensin II receptor Human genes 0.000 description 1
• 102100033438 Tyrosine-protein kinase JAK1 Human genes 0.000 description 1
• 102100033444 Tyrosine-protein kinase JAK2 Human genes 0.000 description 1
• 102100033020 Tyrosine-protein phosphatase non-receptor type 12 Human genes 0.000 description 1
• 102100021722 Tyrosine-protein phosphatase non-receptor type 9 Human genes 0.000 description 1
• 102100024579 Tyrosyl-DNA phosphodiesterase 1 Human genes 0.000 description 1
• 108091026822 U6 spliceosomal RNA Proteins 0.000 description 1
• 101150027514 UBE2C gene Proteins 0.000 description 1
• HSCJRCZFDFQWRP-JZMIEXBBSA-N UDP-alpha-D-glucose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OP(O)(=O)OP(O)(=O)OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(NC(=O)C=C2)=O)O1 HSCJRCZFDFQWRP-JZMIEXBBSA-N 0.000 description 1
• 102100029152 UDP-glucuronosyltransferase 1A1 Human genes 0.000 description 1
• 101710205316 UDP-glucuronosyltransferase 1A1 Proteins 0.000 description 1
• 102100021441 UPF0687 protein C20orf27 Human genes 0.000 description 1
• 102100032993 UPF0739 protein C1orf74 Human genes 0.000 description 1
• 108090000848 Ubiquitin Proteins 0.000 description 1
• 102000044159 Ubiquitin Human genes 0.000 description 1
• 108010005656 Ubiquitin Thiolesterase Proteins 0.000 description 1
• 102100024720 Ubiquitin carboxyl-terminal hydrolase 13 Human genes 0.000 description 1
• 102100025038 Ubiquitin carboxyl-terminal hydrolase isozyme L1 Human genes 0.000 description 1
• 102100037256 Ubiquitin-conjugating enzyme E2 C Human genes 0.000 description 1
• 102100028705 Ubiquitin-conjugating enzyme E2 T Human genes 0.000 description 1
• 102100037938 Ubiquitin-like modifier-activating enzyme 7 Human genes 0.000 description 1
• 102100027266 Ubiquitin-like protein ISG15 Human genes 0.000 description 1
• 102100025480 Uncharacterized protein C1orf115 Human genes 0.000 description 1
• 102100035820 Unconventional myosin-Ie Human genes 0.000 description 1
• 108091023045 Untranslated Region Proteins 0.000 description 1
• 229910052770 Uranium Inorganic materials 0.000 description 1
• HSCJRCZFDFQWRP-UHFFFAOYSA-N Uridindiphosphoglukose Natural products OC1C(O)C(O)C(CO)OC1OP(O)(=O)OP(O)(=O)OCC1C(O)C(O)C(N2C(NC(=O)C=C2)=O)O1 HSCJRCZFDFQWRP-UHFFFAOYSA-N 0.000 description 1
• 102100039543 Uveal autoantigen with coiled-coil domains and ankyrin repeats Human genes 0.000 description 1
• 102000008790 VE-cadherin Human genes 0.000 description 1
• 108010034265 Vascular Endothelial Growth Factor Receptors Proteins 0.000 description 1
• 102100038232 Vascular endothelial growth factor C Human genes 0.000 description 1
• 102100038388 Vasoactive intestinal polypeptide receptor 1 Human genes 0.000 description 1
• 101710137655 Vasoactive intestinal polypeptide receptor 1 Proteins 0.000 description 1
• 102100028437 Versican core protein Human genes 0.000 description 1
• 102100028759 Vesicle-trafficking protein SEC22c Human genes 0.000 description 1
• 241000711975 Vesicular stomatitis virus Species 0.000 description 1
• 235000009754 Vitis X bourquina Nutrition 0.000 description 1
• 235000012333 Vitis X labruscana Nutrition 0.000 description 1
• 240000006365 Vitis vinifera Species 0.000 description 1
• 235000014787 Vitis vinifera Nutrition 0.000 description 1
• 102000021095 WAP Four-Disulfide Core Domain Protein 2 Human genes 0.000 description 1
• 108091002660 WAP Four-Disulfide Core Domain Protein 2 Proteins 0.000 description 1
• 102100038965 WAP four-disulfide core domain protein 2 Human genes 0.000 description 1
• 208000013058 Weber syndrome Diseases 0.000 description 1
• 108010062653 Wiskott-Aldrich Syndrome Protein Family Proteins 0.000 description 1
• 102000011104 Wiskott-Aldrich Syndrome Protein Family Human genes 0.000 description 1
• 206010048215 Xanthomatosis Diseases 0.000 description 1
• 241000269368 Xenopus laevis Species 0.000 description 1
• 101000690559 Xenopus laevis Anterior gradient protein 2 Proteins 0.000 description 1
• 108010063641 Xylosylprotein 4-beta-galactosyltransferase Proteins 0.000 description 1
• 210000002593 Y chromosome Anatomy 0.000 description 1
• 102100032803 Y+L amino acid transporter 2 Human genes 0.000 description 1
• 102100036644 Zinc finger CCCH domain-containing protein 7A Human genes 0.000 description 1
• 102100028477 Zinc finger CCHC domain-containing protein 14 Human genes 0.000 description 1
• 102100040761 Zinc finger and BTB domain-containing protein 17 Human genes 0.000 description 1
• 102100023577 Zinc finger protein 106 Human genes 0.000 description 1
• 102100026521 Zinc finger protein 266 Human genes 0.000 description 1
• 102100023554 Zinc finger protein 408 Human genes 0.000 description 1
• 102100026487 Zinc finger protein 862 Human genes 0.000 description 1
• 102100028959 Zinc finger protein ZPR1 Human genes 0.000 description 1
• 102100021421 Zinc transporter 9 Human genes 0.000 description 1
• 102100035247 Zinc transporter ZIP11 Human genes 0.000 description 1
• 244000273928 Zingiber officinale Species 0.000 description 1
• 235000006886 Zingiber officinale Nutrition 0.000 description 1
• HMNZFMSWFCAGGW-XPWSMXQVSA-N [3-[hydroxy(2-hydroxyethoxy)phosphoryl]oxy-2-[(e)-octadec-9-enoyl]oxypropyl] (e)-octadec-9-enoate Chemical compound CCCCCCCC\C=C\CCCCCCCC(=O)OCC(COP(O)(=O)OCCO)OC(=O)CCCCCCC\C=C\CCCCCCCC HMNZFMSWFCAGGW-XPWSMXQVSA-N 0.000 description 1
• FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
• 102100034825 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial Human genes 0.000 description 1
• 230000002159 abnormal effect Effects 0.000 description 1
• 229940100228 acetyl coenzyme a Drugs 0.000 description 1
• 230000002378 acidificating effect Effects 0.000 description 1
• 230000009471 action Effects 0.000 description 1
• 239000012190 activator Substances 0.000 description 1
• 239000000488 activin Substances 0.000 description 1
• 108010023082 activin A Proteins 0.000 description 1
• 201000008395 adenosquamous carcinoma Diseases 0.000 description 1
• 239000000853 adhesive Substances 0.000 description 1
• 230000001070 adhesive effect Effects 0.000 description 1
• 210000001789 adipocyte Anatomy 0.000 description 1
• 230000009815 adipogenic differentiation Effects 0.000 description 1
• 239000002671 adjuvant Substances 0.000 description 1
• 230000006838 adverse reaction Effects 0.000 description 1
• 230000004520 agglutination Effects 0.000 description 1
• 125000001931 aliphatic group Chemical group 0.000 description 1
• 102000009120 alpha Subunit Hypoxia-Inducible Factor 1 Human genes 0.000 description 1
• 108010048418 alpha Subunit Hypoxia-Inducible Factor 1 Proteins 0.000 description 1
• 108010075843 alpha-2-HS-Glycoprotein Proteins 0.000 description 1
• 102000012005 alpha-2-HS-Glycoprotein Human genes 0.000 description 1
• 150000001409 amidines Chemical class 0.000 description 1
• 125000003277 amino group Chemical group 0.000 description 1
• 229940035676 analgesics Drugs 0.000 description 1
• 108010072788 angiogenin Proteins 0.000 description 1
• 230000008485 antagonism Effects 0.000 description 1
• 239000000730 antalgic agent Substances 0.000 description 1
• 230000003141 anti-fusion Effects 0.000 description 1
• 230000005904 anticancer immunity Effects 0.000 description 1
• 239000004599 antimicrobial Substances 0.000 description 1
• 229940041181 antineoplastic drug Drugs 0.000 description 1
• 239000003963 antioxidant agent Substances 0.000 description 1
• 230000003078 antioxidant effect Effects 0.000 description 1
• 235000006708 antioxidants Nutrition 0.000 description 1
• 230000005975 antitumor immune response Effects 0.000 description 1
• 210000000709 aorta Anatomy 0.000 description 1
• 230000006907 apoptotic process Effects 0.000 description 1
• PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 1
• 150000001491 aromatic compounds Chemical class 0.000 description 1
• 238000005899 aromatization reaction Methods 0.000 description 1
• 208000006673 asthma Diseases 0.000 description 1
• QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
• 230000002358 autolytic effect Effects 0.000 description 1
• 230000002567 autonomic effect Effects 0.000 description 1
• 239000000022 bacteriostatic agent Substances 0.000 description 1
• 210000000227 basophil cell of anterior lobe of hypophysis Anatomy 0.000 description 1
• 239000011324 bead Substances 0.000 description 1
• SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 1
• 239000011230 binding agent Substances 0.000 description 1
• 239000012620 biological material Substances 0.000 description 1
• 229960002685 biotin Drugs 0.000 description 1
• 235000020958 biotin Nutrition 0.000 description 1
• 239000011616 biotin Substances 0.000 description 1
• 230000000903 blocking effect Effects 0.000 description 1
• 230000037396 body weight Effects 0.000 description 1
• 210000001185 bone marrow Anatomy 0.000 description 1
• 108010047153 bovine corneal protein 54 Proteins 0.000 description 1
• 210000004556 brain Anatomy 0.000 description 1
• 201000007293 brain stem infarction Diseases 0.000 description 1
• 238000009395 breeding Methods 0.000 description 1
• 230000001488 breeding effect Effects 0.000 description 1
• GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 1
• 229910052794 bromium Inorganic materials 0.000 description 1
• 210000004899 c-terminal region Anatomy 0.000 description 1
• 102100023514 cAMP-dependent protein kinase inhibitor gamma Human genes 0.000 description 1
• 108010018828 cadherin 5 Proteins 0.000 description 1
• BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 description 1
• 229960004015 calcitonin Drugs 0.000 description 1
• 238000004364 calculation method Methods 0.000 description 1
• 235000009120 camo Nutrition 0.000 description 1
• 230000005907 cancer growth Effects 0.000 description 1
• 150000001720 carbohydrates Chemical class 0.000 description 1
• 235000014633 carbohydrates Nutrition 0.000 description 1
• 229910052799 carbon Inorganic materials 0.000 description 1
• 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 1
• 239000003183 carcinogenic agent Substances 0.000 description 1
• 210000004413 cardiac myocyte Anatomy 0.000 description 1
• 239000000969 carrier Substances 0.000 description 1
• 101150055766 cat gene Proteins 0.000 description 1
• 230000003197 catalytic effect Effects 0.000 description 1
• 238000004113 cell culture Methods 0.000 description 1
• 230000005779 cell damage Effects 0.000 description 1
• 230000024245 cell differentiation Effects 0.000 description 1
• 230000032823 cell division Effects 0.000 description 1
• 208000037887 cell injury Diseases 0.000 description 1
• 239000013592 cell lysate Substances 0.000 description 1
• 210000000170 cell membrane Anatomy 0.000 description 1
• 230000005859 cell recognition Effects 0.000 description 1
• 230000010307 cell transformation Effects 0.000 description 1
• 230000003833 cell viability Effects 0.000 description 1
• 239000001913 cellulose Substances 0.000 description 1
• 229920002678 cellulose Polymers 0.000 description 1
• 238000005119 centrifugation Methods 0.000 description 1
• 235000013339 cereals Nutrition 0.000 description 1
• 230000002490 cerebral effect Effects 0.000 description 1
• 235000005607 chanvre indien Nutrition 0.000 description 1
• 238000001311 chemical methods and process Methods 0.000 description 1
• 238000006243 chemical reaction Methods 0.000 description 1
• 239000007795 chemical reaction product Substances 0.000 description 1
• 238000002512 chemotherapy Methods 0.000 description 1
• 235000012000 cholesterol Nutrition 0.000 description 1
• 108010023417 cholesterol dehydrogenase Proteins 0.000 description 1
• DLGJWSVWTWEWBJ-HGGSSLSASA-N chondroitin Chemical compound CC(O)=N[C@@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1OC1[C@H](O)[C@H](O)C=C(C(O)=O)O1 DLGJWSVWTWEWBJ-HGGSSLSASA-N 0.000 description 1
• 238000004587 chromatography analysis Methods 0.000 description 1
• 230000002759 chromosomal effect Effects 0.000 description 1
• 208000024207 chronic leukemia Diseases 0.000 description 1
• 229940043370 chrysin Drugs 0.000 description 1
• 235000015838 chrysin Nutrition 0.000 description 1
• 210000000078 claw Anatomy 0.000 description 1
• 238000003759 clinical diagnosis Methods 0.000 description 1
• 229920001436 collagen Polymers 0.000 description 1
• 229960002424 collagenase Drugs 0.000 description 1
• 239000002442 collagenase inhibitor Substances 0.000 description 1
• 108010057108 condensin complexes Proteins 0.000 description 1
• 208000018697 congenital contractures Diseases 0.000 description 1
• 210000002808 connective tissue Anatomy 0.000 description 1
• 108010015416 connexin 32 Proteins 0.000 description 1
• 238000013270 controlled release Methods 0.000 description 1
• 239000006071 cream Substances 0.000 description 1
• 229960003624 creatine Drugs 0.000 description 1
• 239000006046 creatine Substances 0.000 description 1
• 238000009402 cross-breeding Methods 0.000 description 1
• 239000013078 crystal Substances 0.000 description 1
• 239000012228 culture supernatant Substances 0.000 description 1
• 230000009089 cytolysis Effects 0.000 description 1
• OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Natural products NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 description 1
• 230000001086 cytosolic effect Effects 0.000 description 1
• 231100000433 cytotoxic Toxicity 0.000 description 1
• 239000002254 cytotoxic agent Substances 0.000 description 1
• 229940127089 cytotoxic agent Drugs 0.000 description 1
• 231100000599 cytotoxic agent Toxicity 0.000 description 1
• 230000001472 cytotoxic effect Effects 0.000 description 1
• 230000034994 death Effects 0.000 description 1
• 230000003247 decreasing effect Effects 0.000 description 1
• 230000007547 defect Effects 0.000 description 1
• 230000007850 degeneration Effects 0.000 description 1
• 108700023159 delta Opioid Receptors Proteins 0.000 description 1
• 102000048124 delta Opioid Receptors Human genes 0.000 description 1
• 239000005547 deoxyribonucleotide Substances 0.000 description 1
• 125000002637 deoxyribonucleotide group Chemical group 0.000 description 1
• 108010049285 dephospho-CoA kinase Proteins 0.000 description 1
• 239000003599 detergent Substances 0.000 description 1
• 238000000502 dialysis Methods 0.000 description 1
• RAABOESOVLLHRU-UHFFFAOYSA-N diazene Chemical compound N=N RAABOESOVLLHRU-UHFFFAOYSA-N 0.000 description 1
• 229910000071 diazene Inorganic materials 0.000 description 1
• 235000014113 dietary fatty acids Nutrition 0.000 description 1
• 230000004069 differentiation Effects 0.000 description 1
• WQOXQRCZOLPYPM-UHFFFAOYSA-N dimethyl disulfide Chemical compound CSSC WQOXQRCZOLPYPM-UHFFFAOYSA-N 0.000 description 1
• SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 description 1
• 230000006806 disease prevention Effects 0.000 description 1
• 208000035475 disorder Diseases 0.000 description 1
• 239000002934 diuretic Substances 0.000 description 1
• 229960003668 docetaxel Drugs 0.000 description 1
• 230000002222 downregulating effect Effects 0.000 description 1
• 239000006196 drop Substances 0.000 description 1
• 229940000406 drug candidate Drugs 0.000 description 1
• 238000012377 drug delivery Methods 0.000 description 1
• 230000004064 dysfunction Effects 0.000 description 1
• 235000013399 edible fruits Nutrition 0.000 description 1
• 108010043837 egg surface sperm receptor Proteins 0.000 description 1
• 235000014103 egg white Nutrition 0.000 description 1
• 210000000969 egg white Anatomy 0.000 description 1
• 238000004520 electroporation Methods 0.000 description 1
• 239000005712 elicitor Substances 0.000 description 1
• 239000000839 emulsion Substances 0.000 description 1
• 210000002472 endoplasmic reticulum Anatomy 0.000 description 1
• 108010018033 endothelial PAS domain-containing protein 1 Proteins 0.000 description 1
• 230000003511 endothelial effect Effects 0.000 description 1
• 230000002708 enhancing effect Effects 0.000 description 1
• 238000006911 enzymatic reaction Methods 0.000 description 1
• 210000003979 eosinophil Anatomy 0.000 description 1
• 230000001973 epigenetic effect Effects 0.000 description 1
• 210000000981 epithelium Anatomy 0.000 description 1
• 108010002591 epsilon receptor Proteins 0.000 description 1
• 230000032050 esterification Effects 0.000 description 1
• 238000005886 esterification reaction Methods 0.000 description 1
• 230000002964 excitative effect Effects 0.000 description 1
• 210000002744 extracellular matrix Anatomy 0.000 description 1
• 238000000605 extraction Methods 0.000 description 1
• 229940012444 factor xiii Drugs 0.000 description 1
• 230000006126 farnesylation Effects 0.000 description 1
• 229930195729 fatty acid Natural products 0.000 description 1
• 239000000194 fatty acid Substances 0.000 description 1
• 150000004665 fatty acids Chemical class 0.000 description 1
• 239000000835 fiber Substances 0.000 description 1
• 229940012952 fibrinogen Drugs 0.000 description 1
• 210000002082 fibula Anatomy 0.000 description 1
• 108090000062 ficolin Proteins 0.000 description 1
• 239000000945 filler Substances 0.000 description 1
• 239000012530 fluid Substances 0.000 description 1
• 239000007850 fluorescent dye Substances 0.000 description 1
• 229910052731 fluorine Inorganic materials 0.000 description 1
• 235000011194 food seasoning agent Nutrition 0.000 description 1
• 238000009472 formulation Methods 0.000 description 1
• 238000013467 fragmentation Methods 0.000 description 1
• 238000006062 fragmentation reaction Methods 0.000 description 1
• 125000000524 functional group Chemical group 0.000 description 1
• BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 description 1
• 239000007789 gas Substances 0.000 description 1
• 238000002309 gasification Methods 0.000 description 1
• 210000001035 gastrointestinal tract Anatomy 0.000 description 1
• 239000000499 gel Substances 0.000 description 1
• 238000001641 gel filtration chromatography Methods 0.000 description 1
• 239000008273 gelatin Substances 0.000 description 1
• 229920000159 gelatin Polymers 0.000 description 1
• 235000019322 gelatine Nutrition 0.000 description 1
• 235000011852 gelatine desserts Nutrition 0.000 description 1
• 238000003209 gene knockout Methods 0.000 description 1
• 238000001415 gene therapy Methods 0.000 description 1
• 102000034356 gene-regulatory proteins Human genes 0.000 description 1
• 108091006104 gene-regulatory proteins Proteins 0.000 description 1
• 238000010353 genetic engineering Methods 0.000 description 1
• 230000007614 genetic variation Effects 0.000 description 1
• 235000008397 ginger Nutrition 0.000 description 1
• 235000008434 ginseng Nutrition 0.000 description 1
• 238000003881 globally optimized alternating phase rectangular pulse Methods 0.000 description 1
• 235000013922 glutamic acid Nutrition 0.000 description 1
• 239000004220 glutamic acid Substances 0.000 description 1
• 108010078430 glutamine phenylacetyltransferase Proteins 0.000 description 1
• 230000036252 glycation Effects 0.000 description 1
• 102000006602 glyceraldehyde-3-phosphate dehydrogenase Human genes 0.000 description 1
• 108020004445 glyceraldehyde-3-phosphate dehydrogenase Proteins 0.000 description 1
• 235000011187 glycerol Nutrition 0.000 description 1
• 108010076513 glycoprotein glycosyltransferase Proteins 0.000 description 1
• 239000003102 growth factor Substances 0.000 description 1
• 102000028718 growth factor binding proteins Human genes 0.000 description 1
• 108091009353 growth factor binding proteins Proteins 0.000 description 1
• 230000009036 growth inhibition Effects 0.000 description 1
• 239000001963 growth medium Substances 0.000 description 1
• RQFCJASXJCIDSX-UUOKFMHZSA-N guanosine 5'-monophosphate Chemical compound C1=2NC(N)=NC(=O)C=2N=CN1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O RQFCJASXJCIDSX-UUOKFMHZSA-N 0.000 description 1
• 239000010440 gypsum Substances 0.000 description 1
• 229910052602 gypsum Inorganic materials 0.000 description 1
• 230000003862 health status Effects 0.000 description 1
• 208000013210 hematogenous Diseases 0.000 description 1
• 108060003552 hemocyanin Proteins 0.000 description 1
• 239000011487 hemp Substances 0.000 description 1
• 206010073071 hepatocellular carcinoma Diseases 0.000 description 1
• 231100000844 hepatocellular carcinoma Toxicity 0.000 description 1
• 150000002402 hexoses Chemical class 0.000 description 1
• 125000000487 histidyl group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C([H])=N1 0.000 description 1
• 102000052964 human C4BPA Human genes 0.000 description 1
• 102000053563 human MYC Human genes 0.000 description 1
• 102000044486 human PAK2 Human genes 0.000 description 1
• 102000053228 human SYTL4 Human genes 0.000 description 1
• 102000049819 human TIMELESS Human genes 0.000 description 1
• 210000005260 human cell Anatomy 0.000 description 1
• 210000003917 human chromosome Anatomy 0.000 description 1
• 239000003906 humectant Substances 0.000 description 1
• 229940099552 hyaluronan Drugs 0.000 description 1
• KIUKXJAPPMFGSW-MNSSHETKSA-N hyaluronan Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H](C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-MNSSHETKSA-N 0.000 description 1
• 108010003425 hyaluronan-mediated motility receptor Proteins 0.000 description 1
• 229960003160 hyaluronic acid Drugs 0.000 description 1
• 150000007857 hydrazones Chemical class 0.000 description 1
• 230000007062 hydrolysis Effects 0.000 description 1
• 238000006460 hydrolysis reaction Methods 0.000 description 1
• 230000002209 hydrophobic effect Effects 0.000 description 1
• KTUFNOKKBVMGRW-UHFFFAOYSA-N imatinib Chemical compound C1CN(C)CCN1CC1=CC=C(C(=O)NC=2C=C(NC=3N=C(C=CN=3)C=3C=NC=CC=3)C(C)=CC=2)C=C1 KTUFNOKKBVMGRW-UHFFFAOYSA-N 0.000 description 1
• 229960002411 imatinib Drugs 0.000 description 1
• 230000002519 immonomodulatory effect Effects 0.000 description 1
• 230000001900 immune effect Effects 0.000 description 1
• 230000008629 immune suppression Effects 0.000 description 1
• 238000003018 immunoassay Methods 0.000 description 1
• 230000016784 immunoglobulin production Effects 0.000 description 1
• 230000001024 immunotherapeutic effect Effects 0.000 description 1
• 230000004054 inflammatory process Effects 0.000 description 1
• 206010022000 influenza Diseases 0.000 description 1
• 238000001802 infusion Methods 0.000 description 1
• 108010019691 inhibin beta A subunit Proteins 0.000 description 1
• 230000005764 inhibitory process Effects 0.000 description 1
• 229940079322 interferon Drugs 0.000 description 1
• 230000000968 intestinal effect Effects 0.000 description 1
• 210000000936 intestine Anatomy 0.000 description 1
• 238000007918 intramuscular administration Methods 0.000 description 1
• 238000001990 intravenous administration Methods 0.000 description 1
• 108010028930 invariant chain Proteins 0.000 description 1
• 230000037427 ion transport Effects 0.000 description 1
• 229940084651 iressa Drugs 0.000 description 1
• JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
• 230000003189 isokinetic effect Effects 0.000 description 1
• 239000007951 isotonicity adjuster Substances 0.000 description 1
• 108010028309 kalinin Proteins 0.000 description 1
• 101150044508 key gene Proteins 0.000 description 1
• 108010045069 keyhole-limpet hemocyanin Proteins 0.000 description 1
• 229940039696 lactobacillus Drugs 0.000 description 1
• 108700010824 lambda-like proteins Proteins 0.000 description 1
• 108010008094 laminin alpha 3 Proteins 0.000 description 1
• 208000003849 large cell carcinoma Diseases 0.000 description 1
• 210000002429 large intestine Anatomy 0.000 description 1
• 230000001418 larval effect Effects 0.000 description 1
• 230000014725 late viral mRNA transcription Effects 0.000 description 1
• 210000002414 leg Anatomy 0.000 description 1
• 230000003902 lesion Effects 0.000 description 1
• 231100000518 lethal Toxicity 0.000 description 1
• 230000001665 lethal effect Effects 0.000 description 1
• VNYSSYRCGWBHLG-AMOLWHMGSA-N leukotriene B4 Chemical compound CCCCC\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC(O)=O VNYSSYRCGWBHLG-AMOLWHMGSA-N 0.000 description 1
• 229930013686 lignan Natural products 0.000 description 1
• 235000009408 lignans Nutrition 0.000 description 1
• 150000005692 lignans Chemical class 0.000 description 1
• 230000004130 lipolysis Effects 0.000 description 1
• 230000002366 lipolytic effect Effects 0.000 description 1
• 239000002502 liposome Substances 0.000 description 1
• 239000007788 liquid Substances 0.000 description 1
• 238000011068 loading method Methods 0.000 description 1
• 239000006210 lotion Substances 0.000 description 1
• 101150084157 lrp-1 gene Proteins 0.000 description 1
• 239000000314 lubricant Substances 0.000 description 1
• 201000005249 lung adenocarcinoma Diseases 0.000 description 1
• 210000002751 lymph Anatomy 0.000 description 1
• 239000006166 lysate Substances 0.000 description 1
• 235000018977 lysine Nutrition 0.000 description 1
• 150000002669 lysines Chemical class 0.000 description 1
• 230000002101 lytic effect Effects 0.000 description 1
• 102100031622 mRNA decay activator protein ZFP36 Human genes 0.000 description 1
• 108010026228 mRNA guanylyltransferase Proteins 0.000 description 1
• YVTIJGPTRUSDKT-AATRIKPKSA-N macrophin Chemical compound COC(=O)\C=C\C=1OC(=O)C(COC(=O)C=C(C)C)=C(OC)C=1CO YVTIJGPTRUSDKT-AATRIKPKSA-N 0.000 description 1
• YVTIJGPTRUSDKT-UHFFFAOYSA-N macrophin Natural products COC(=O)C=CC1=C(CO)C(=C(COC(=O)C=C(C)C)C(=O)O1)OC YVTIJGPTRUSDKT-UHFFFAOYSA-N 0.000 description 1
• 230000023508 male gonad development Effects 0.000 description 1
• 210000001595 mastoid Anatomy 0.000 description 1
• 239000000463 material Substances 0.000 description 1
• 235000012054 meals Nutrition 0.000 description 1
• 238000005259 measurement Methods 0.000 description 1
• 239000002609 medium Substances 0.000 description 1
• 238000002844 melting Methods 0.000 description 1
• 230000008018 melting Effects 0.000 description 1
• 230000023881 membrane protein ectodomain proteolysis Effects 0.000 description 1
• 229960003151 mercaptamine Drugs 0.000 description 1
• 238000010197 meta-analysis Methods 0.000 description 1
• 230000002503 metabolic effect Effects 0.000 description 1
• 230000003458 metachromatic effect Effects 0.000 description 1
• 229910021645 metal ion Inorganic materials 0.000 description 1
• 239000003475 metalloproteinase inhibitor Substances 0.000 description 1
• 229940126170 metalloproteinase inhibitor Drugs 0.000 description 1
• 230000009401 metastasis Effects 0.000 description 1
• 238000010208 microarray analysis Methods 0.000 description 1
• 238000012775 microarray technology Methods 0.000 description 1
• 238000012737 microarray-based gene expression Methods 0.000 description 1
• 244000005700 microbiome Species 0.000 description 1
• 239000003094 microcapsule Substances 0.000 description 1
• 239000003658 microfiber Substances 0.000 description 1
• 210000003632 microfilament Anatomy 0.000 description 1
• 230000003228 microsomal effect Effects 0.000 description 1
• 210000001589 microsome Anatomy 0.000 description 1
• 206010027599 migraine Diseases 0.000 description 1
• 102000035118 modified proteins Human genes 0.000 description 1
• 108091005573 modified proteins Proteins 0.000 description 1
• 239000003147 molecular marker Substances 0.000 description 1
• 150000002762 monocarboxylic acid derivatives Chemical class 0.000 description 1
• 210000005087 mononuclear cell Anatomy 0.000 description 1
• 238000012243 multiplex automated genomic engineering Methods 0.000 description 1
• 230000004118 muscle contraction Effects 0.000 description 1
• 230000002107 myocardial effect Effects 0.000 description 1
• 210000004165 myocardium Anatomy 0.000 description 1
• RIWRFSMVIUAEBX-UHFFFAOYSA-N n-methyl-1-phenylmethanamine Chemical compound CNCC1=CC=CC=C1 RIWRFSMVIUAEBX-UHFFFAOYSA-N 0.000 description 1
• 239000007923 nasal drop Substances 0.000 description 1
• 229940100662 nasal drops Drugs 0.000 description 1
• 230000001452 natriuretic effect Effects 0.000 description 1
• 102000027424 natriuretic peptide receptors Human genes 0.000 description 1
• 108091008599 natriuretic peptide receptors Proteins 0.000 description 1
• 210000000822 natural killer cell Anatomy 0.000 description 1
• 229930014626 natural product Natural products 0.000 description 1
• 239000013642 negative control Substances 0.000 description 1
• 210000005036 nerve Anatomy 0.000 description 1
• 210000005055 nestin Anatomy 0.000 description 1
• 108010021512 neuromedin U Proteins 0.000 description 1
• 210000000440 neutrophil Anatomy 0.000 description 1
• 229920001220 nitrocellulos Polymers 0.000 description 1
• 229910052757 nitrogen Inorganic materials 0.000 description 1
• 230000000683 nonmetastatic effect Effects 0.000 description 1
• 235000012149 noodles Nutrition 0.000 description 1
• 102000006255 nuclear receptors Human genes 0.000 description 1
• 108020004017 nuclear receptors Proteins 0.000 description 1
• 239000002777 nucleoside Substances 0.000 description 1
• 150000003833 nucleoside derivatives Chemical class 0.000 description 1
• 102000037831 nucleoside transporters Human genes 0.000 description 1
• 108091006527 nucleoside transporters Proteins 0.000 description 1
• 210000001623 nucleosome Anatomy 0.000 description 1
• 238000011275 oncology therapy Methods 0.000 description 1
• 238000010397 one-hybrid screening Methods 0.000 description 1
• 239000011022 opal Substances 0.000 description 1
• 150000002894 organic compounds Chemical class 0.000 description 1
• 230000002188 osteogenic effect Effects 0.000 description 1
• 238000007500 overflow downdraw method Methods 0.000 description 1
• 230000001590 oxidative effect Effects 0.000 description 1
• 229910052760 oxygen Inorganic materials 0.000 description 1
• 239000001301 oxygen Substances 0.000 description 1
• 108010001073 oxyhemoglobin oxidase Proteins 0.000 description 1
• 125000001312 palmitoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
• 201000002528 pancreatic cancer Diseases 0.000 description 1
• 238000004091 panning Methods 0.000 description 1
• 230000007903 penetration ability Effects 0.000 description 1
• 108010091742 peptide F Proteins 0.000 description 1
• RJSZPKZQGIKVAU-UXBJKDEOSA-N peptide f Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(O)=O)NC(=O)CNC(=O)CNC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C(C)C)C(C)C)C1=CC=CC=C1 RJSZPKZQGIKVAU-UXBJKDEOSA-N 0.000 description 1
• 102000014187 peptide receptors Human genes 0.000 description 1
• 108010011903 peptide receptors Proteins 0.000 description 1
• 229940023041 peptide vaccine Drugs 0.000 description 1
• 230000003132 peptidolytic effect Effects 0.000 description 1
• 239000000816 peptidomimetic Substances 0.000 description 1
• 229920001192 peptidylglycine Polymers 0.000 description 1
• 230000035699 permeability Effects 0.000 description 1
• 239000000546 pharmaceutical excipient Substances 0.000 description 1
• 239000010452 phosphate Substances 0.000 description 1
• 150000003904 phospholipids Chemical class 0.000 description 1
• PTMHPRAIXMAOOB-UHFFFAOYSA-N phosphoramidic acid Chemical group NP(O)(O)=O PTMHPRAIXMAOOB-UHFFFAOYSA-N 0.000 description 1
• 108010045959 phosphoribosyl pyrophosphate aminotransferase Proteins 0.000 description 1
• 230000026731 phosphorylation Effects 0.000 description 1
• 238000006366 phosphorylation reaction Methods 0.000 description 1
• 239000002504 physiological saline solution Substances 0.000 description 1
• 239000000049 pigment Substances 0.000 description 1
• 210000002826 placenta Anatomy 0.000 description 1
• 239000000419 plant extract Substances 0.000 description 1
• 210000004180 plasmocyte Anatomy 0.000 description 1
• 210000002706 plastid Anatomy 0.000 description 1
• 108010026735 platelet protein P47 Proteins 0.000 description 1
• 238000011518 platinum-based chemotherapy Methods 0.000 description 1
• OYEHPCDNVJXUIW-UHFFFAOYSA-N plutonium atom Chemical group [Pu] OYEHPCDNVJXUIW-UHFFFAOYSA-N 0.000 description 1
• 102000004401 podocalyxin Human genes 0.000 description 1
• 108090000917 podocalyxin Proteins 0.000 description 1
• 108010005636 polypeptide C Proteins 0.000 description 1
• 239000013641 positive control Substances 0.000 description 1
• 229910052700 potassium Inorganic materials 0.000 description 1
• 230000003334 potential effect Effects 0.000 description 1
• 244000144977 poultry Species 0.000 description 1
• 239000003755 preservative agent Substances 0.000 description 1
• 230000003449 preventive effect Effects 0.000 description 1
• 230000008569 process Effects 0.000 description 1
• 238000012545 processing Methods 0.000 description 1
• 102000016670 prohibitin Human genes 0.000 description 1
• 108010028138 prohibitin Proteins 0.000 description 1
• AAEVYOVXGOFMJO-UHFFFAOYSA-N prometryn Chemical compound CSC1=NC(NC(C)C)=NC(NC(C)C)=N1 AAEVYOVXGOFMJO-UHFFFAOYSA-N 0.000 description 1
• 150000003180 prostaglandins Chemical class 0.000 description 1
• 108010042388 protease C Proteins 0.000 description 1
• 230000001012 protector Effects 0.000 description 1
• 229960000856 protein c Drugs 0.000 description 1
• 238000002331 protein detection Methods 0.000 description 1
• 239000003528 protein farnesyltransferase inhibitor Substances 0.000 description 1
• 230000012743 protein tagging Effects 0.000 description 1
• 238000000746 purification Methods 0.000 description 1
• 239000002213 purine nucleotide Substances 0.000 description 1
• 150000003212 purines Chemical class 0.000 description 1
• 229910052704 radon Inorganic materials 0.000 description 1
• SYUHGPGVQRZVTB-UHFFFAOYSA-N radon atom Chemical compound [Rn] SYUHGPGVQRZVTB-UHFFFAOYSA-N 0.000 description 1
• 108091008598 receptor tyrosine kinases Proteins 0.000 description 1
• 102000027426 receptor tyrosine kinases Human genes 0.000 description 1
• 206010038038 rectal cancer Diseases 0.000 description 1
• 201000001275 rectum cancer Diseases 0.000 description 1
• 230000000306 recurrent effect Effects 0.000 description 1
• 230000002829 reductive effect Effects 0.000 description 1
• 125000006853 reporter group Chemical group 0.000 description 1
• 108091008146 restriction endonucleases Proteins 0.000 description 1
• 230000000717 retained effect Effects 0.000 description 1
• 230000004258 retinal degeneration Effects 0.000 description 1
• 230000002207 retinal effect Effects 0.000 description 1
• 210000000844 retinal pigment epithelial cell Anatomy 0.000 description 1
• 229960003471 retinol Drugs 0.000 description 1
• 235000020944 retinol Nutrition 0.000 description 1
• 239000011607 retinol Substances 0.000 description 1
• 238000010839 reverse transcription Methods 0.000 description 1
• 108010052833 ribonuclease HI Proteins 0.000 description 1
• 239000002342 ribonucleoside Substances 0.000 description 1
• 108010074916 ribophorin Proteins 0.000 description 1
• 108010019034 ribosomal protein L18a Proteins 0.000 description 1
• 108010025387 ribosomal protein L39 Proteins 0.000 description 1
• 108010093173 ribosomal protein S29 Proteins 0.000 description 1
• 210000003705 ribosome Anatomy 0.000 description 1
• 230000000630 rising effect Effects 0.000 description 1
• 210000003079 salivary gland Anatomy 0.000 description 1
• 238000003118 sandwich ELISA Methods 0.000 description 1
• 201000000306 sarcoidosis Diseases 0.000 description 1
• 230000007017 scission Effects 0.000 description 1
• 238000000926 separation method Methods 0.000 description 1
• 210000002966 serum Anatomy 0.000 description 1
• 235000015170 shellfish Nutrition 0.000 description 1
• 210000002027 skeletal muscle Anatomy 0.000 description 1
• 239000011780 sodium chloride Substances 0.000 description 1
• 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 1
• 239000002689 soil Substances 0.000 description 1
• 239000007790 solid phase Substances 0.000 description 1
• 238000010532 solid phase synthesis reaction Methods 0.000 description 1
• 239000002904 solvent Substances 0.000 description 1
• 230000000392 somatic effect Effects 0.000 description 1
• 125000006850 spacer group Chemical group 0.000 description 1
• 241000894007 species Species 0.000 description 1
• 238000001228 spectrum Methods 0.000 description 1
• 230000021595 spermatogenesis Effects 0.000 description 1
• 229940063675 spermine Drugs 0.000 description 1
• WWUZIQQURGPMPG-KRWOKUGFSA-N sphingosine Chemical compound CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)CO WWUZIQQURGPMPG-KRWOKUGFSA-N 0.000 description 1
• 230000009192 sprinting Effects 0.000 description 1
• 206010041823 squamous cell carcinoma Diseases 0.000 description 1
• 238000010186 staining Methods 0.000 description 1
• 238000010561 standard procedure Methods 0.000 description 1
• 210000000130 stem cell Anatomy 0.000 description 1
• 230000001954 sterilising effect Effects 0.000 description 1
• 238000004659 sterilization and disinfection Methods 0.000 description 1
• 108010085346 steroid delta-isomerase Proteins 0.000 description 1
• 210000002784 stomach Anatomy 0.000 description 1
• 239000004575 stone Substances 0.000 description 1
• 238000007920 subcutaneous administration Methods 0.000 description 1
• 239000005720 sucrose Substances 0.000 description 1
• 108010006247 sulfoxide reductase Proteins 0.000 description 1
• 239000011593 sulfur Substances 0.000 description 1
• 125000004434 sulfur atom Chemical group 0.000 description 1
• 239000013589 supplement Substances 0.000 description 1
• 230000001629 suppression Effects 0.000 description 1
• 208000024891 symptom Diseases 0.000 description 1
• 108010016910 synaptojanin Proteins 0.000 description 1
• 102000000580 synaptojanin Human genes 0.000 description 1
• 208000011580 syndromic disease Diseases 0.000 description 1
• 230000002194 synthesizing effect Effects 0.000 description 1
• 230000009885 systemic effect Effects 0.000 description 1
• 102100032270 tRNA (cytosine(38)-C(5))-methyltransferase Human genes 0.000 description 1
• 101710184308 tRNA (cytosine(38)-C(5))-methyltransferase Proteins 0.000 description 1
• 102100028986 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like Human genes 0.000 description 1
• 239000003826 tablet Substances 0.000 description 1
• 238000002626 targeted therapy Methods 0.000 description 1
• 230000008685 targeting Effects 0.000 description 1
• 210000002435 tendon Anatomy 0.000 description 1
• 229960003604 testosterone Drugs 0.000 description 1
• 235000019157 thiamine Nutrition 0.000 description 1
• KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 description 1
• 229960003495 thiamine Drugs 0.000 description 1
• 239000011721 thiamine Substances 0.000 description 1
• RYYWUUFWQRZTIU-UHFFFAOYSA-K thiophosphate Chemical group [O-]P([O-])([O-])=S RYYWUUFWQRZTIU-UHFFFAOYSA-K 0.000 description 1
• 229960004072 thrombin Drugs 0.000 description 1
• 230000009424 thromboembolic effect Effects 0.000 description 1
• 210000001541 thymus gland Anatomy 0.000 description 1
• 229940098465 tincture Drugs 0.000 description 1
• 238000011200 topical administration Methods 0.000 description 1
• 230000000699 topical effect Effects 0.000 description 1
• 238000012549 training Methods 0.000 description 1
• 108091006108 transcriptional coactivators Proteins 0.000 description 1
• 238000005809 transesterification reaction Methods 0.000 description 1
• 230000009261 transgenic effect Effects 0.000 description 1
• 102000027257 transmembrane receptors Human genes 0.000 description 1
• 108091008578 transmembrane receptors Proteins 0.000 description 1
• PYHOFAHZHOBVGV-UHFFFAOYSA-N triazane Chemical compound NNN PYHOFAHZHOBVGV-UHFFFAOYSA-N 0.000 description 1
• PUXBEKLSMBVFNW-UHFFFAOYSA-N triphenylene-2,3,6,7,10,11-hexamine hexahydrochloride Chemical compound Cl.Cl.Cl.Cl.Cl.Cl.NC1=CC=2C3=CC(=C(C=C3C3=CC(=C(C=C3C2C=C1N)N)N)N)N PUXBEKLSMBVFNW-UHFFFAOYSA-N 0.000 description 1
• 150000004043 trisaccharides Chemical class 0.000 description 1
• 229910052722 tritium Inorganic materials 0.000 description 1
• 102000012344 tuftelin Human genes 0.000 description 1
• 108010022248 tuftelin Proteins 0.000 description 1
• 230000005740 tumor formation Effects 0.000 description 1
• 239000000439 tumor marker Substances 0.000 description 1
• 229910052721 tungsten Inorganic materials 0.000 description 1
• 238000003160 two-hybrid assay Methods 0.000 description 1
• 229960003732 tyramine Drugs 0.000 description 1
• 150000004917 tyrosine kinase inhibitor derivatives Chemical class 0.000 description 1
• 108010000982 uK-ATP-1 potassium channel Proteins 0.000 description 1
• 241000712461 unidentified influenza virus Species 0.000 description 1
• 230000003827 upregulation Effects 0.000 description 1
• 238000011144 upstream manufacturing Methods 0.000 description 1
• JFALSRSLKYAFGM-UHFFFAOYSA-N uranium(0) Chemical compound [U] JFALSRSLKYAFGM-UHFFFAOYSA-N 0.000 description 1
• 238000002255 vaccination Methods 0.000 description 1
• 229910052720 vanadium Inorganic materials 0.000 description 1
• 230000026492 vascular transport Effects 0.000 description 1
• 239000003981 vehicle Substances 0.000 description 1
• 210000003462 vein Anatomy 0.000 description 1
• WQAJKOXBERTWBK-UHFFFAOYSA-N verdine Natural products CC1CNC2C(C1)OC3(CCC4C5CCC6(O)CC(O)CC(O)C6(C)C5C(=O)C4=C3C)C2C WQAJKOXBERTWBK-UHFFFAOYSA-N 0.000 description 1
• 229940088594 vitamin Drugs 0.000 description 1
• 229930003231 vitamin Natural products 0.000 description 1
• 235000013343 vitamin Nutrition 0.000 description 1
• 239000011782 vitamin Substances 0.000 description 1
• 150000003722 vitamin derivatives Chemical class 0.000 description 1
• 238000005406 washing Methods 0.000 description 1
• 239000008215 water for injection Substances 0.000 description 1
• 238000001262 western blot Methods 0.000 description 1
• 238000009736 wetting Methods 0.000 description 1
• 229910052727 yttrium Inorganic materials 0.000 description 1