JP2006276000A5 - - Google Patents

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Publication number
JP2006276000A5
JP2006276000A5 JP2005303835A JP2005303835A JP2006276000A5 JP 2006276000 A5 JP2006276000 A5 JP 2006276000A5 JP 2005303835 A JP2005303835 A JP 2005303835A JP 2005303835 A JP2005303835 A JP 2005303835A JP 2006276000 A5 JP2006276000 A5 JP 2006276000A5
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JP
Japan
Prior art keywords
substrate
layer
fluorescence detection
sample
dielectric film
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2005303835A
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English (en)
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JP4812393B2 (ja
JP2006276000A (ja
Filing date
Publication date
Application filed filed Critical
Priority to JP2005303835A priority Critical patent/JP4812393B2/ja
Priority claimed from JP2005303835A external-priority patent/JP4812393B2/ja
Priority to US11/349,898 priority patent/US7439522B2/en
Publication of JP2006276000A publication Critical patent/JP2006276000A/ja
Publication of JP2006276000A5 publication Critical patent/JP2006276000A5/ja
Application granted granted Critical
Publication of JP4812393B2 publication Critical patent/JP4812393B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Claims (5)

  1. 第１の基板と第２の基板とを具備し，前記第１と第２の基板の間に試料溶液を保持する
    試料保持部と，
    前記第１の基板と前記第２の基板との間へ励起光を照射する光照射部と，
    前記試料保持部の内部で生じる蛍光を検出する検出部と，
    前記試料保持部を前記検出部に対して相対的，機械的に移動させる移動手段とを有する
    ことを特徴とする蛍光検出装置。
  2. 前記第１の基板と前記第２の基板とは，各々の向き合う面に各々第１の層と第２の層と
    を有し，前記第１の層と前記第２の層とは前記試料よりも屈折率が低いことを特徴とする
    請求項１に記載の蛍光検出装置。
  3. 前記第１の基板と前記第２の基板とは，各々の向き合う面に各々第１の誘電体膜と第２
    の誘電体膜とを有し，前記第１の誘電体膜と前記第２の誘電体膜とは，前記第１の基板及
    び前記第２の基板よりも屈折率が高いことを特徴とする請求項１に記載の蛍光検出装置。
  4. 前記第１の基板及び前記第２の基板が水平に設置されることを特徴とする請求項１内至
    請求項３に記載の蛍光検出装置。
  5. 前記第１の基板と前記第２の基板とは実質的に平行に設置されることを特徴とする請求
    項１内至請求項３に記載の蛍光検出装置。
JP2005303835A 2005-03-04 2005-10-19 蛍光分子計測システム Expired - Fee Related JP4812393B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2005303835A JP4812393B2 (ja) 2005-03-04 2005-10-19 蛍光分子計測システム
US11/349,898 US7439522B2 (en) 2005-03-04 2006-02-09 Counting system for fluorescent molecules

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2005059858 2005-03-04
JP2005059858 2005-03-04
JP2005303835A JP4812393B2 (ja) 2005-03-04 2005-10-19 蛍光分子計測システム

Publications (3)

Publication Number Publication Date
JP2006276000A JP2006276000A (ja) 2006-10-12
JP2006276000A5 true JP2006276000A5 (ja) 2008-05-01
JP4812393B2 JP4812393B2 (ja) 2011-11-09

Family

ID=36943257

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2005303835A Expired - Fee Related JP4812393B2 (ja) 2005-03-04 2005-10-19 蛍光分子計測システム

Country Status (2)

Country Link
US (1) US7439522B2 (ja)
JP (1) JP4812393B2 (ja)

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WO2010085548A2 (en) * 2009-01-22 2010-07-29 Li-Cor, Inc. Single molecule proteomics with dynamic probes
US8993972B2 (en) * 2009-01-23 2015-03-31 University Of Maryland Baltimore County Fluorescence based sensors utilizing a mirrored cavity
JP5660464B2 (ja) * 2011-07-25 2015-01-28 横河電機株式会社 濃度測定方法、および濃度測定システム
KR20140090509A (ko) * 2013-01-09 2014-07-17 성균관대학교산학협력단 내부 전반사기를 이용한 형광 검출 장치
CN103776806B (zh) * 2014-01-06 2016-01-06 浙江农林大学 包合物包合率测定仪的测定方法
JP2015184114A (ja) * 2014-03-24 2015-10-22 富士フイルム株式会社 増強ラマン分光装置
JPWO2016063912A1 (ja) 2014-10-24 2017-08-03 国立大学法人 東京大学 粒子検出方法、粒子検出装置および粒子検出システム
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