AR058616A1 - Dispositivo y procedimiento para la deteccion de micotoxinas - Google Patents

Dispositivo y procedimiento para la deteccion de micotoxinas

Info

Publication number
AR058616A1
AR058616A1 ARP060105723A ARP060105723A AR058616A1 AR 058616 A1 AR058616 A1 AR 058616A1 AR P060105723 A ARP060105723 A AR P060105723A AR P060105723 A ARP060105723 A AR P060105723A AR 058616 A1 AR058616 A1 AR 058616A1
Authority
AR
Argentina
Prior art keywords
mycotoxins
immobilized
procedure
binding
binding entities
Prior art date
Application number
ARP060105723A
Other languages
English (en)
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of AR058616A1 publication Critical patent/AR058616A1/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7786—Fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Plasma & Fusion (AREA)
  • Optics & Photonics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Dispositivo y procedimiento para la deteccion de micotoxinas así como kits adecuados para la realizacion del procedimiento. Reivindicacion 1: Procedimiento para la deteccion rápida de micotoxinas, que comprende las siguientes etapas: a) preparar un guiaondas de capa fina que comprende una primera capa (a) de guiaondas opticamente transparente sobre una segunda capa (b) opticamente transparente, en donde (b) posee un índice de refraccion menor que (a), sobre la que se inmovilizan separados espacialmente entes de union específicos y/o afines como elemento de reconocimiento químico o bioquímico para micotoxinas y/o un ente de union; b) aplicacion de una muestra que contiene micotoxina(s) y de entes de union a los entes de union inmovilizados sobre el guiaondas de capa fina; c) detectar una senal en el campo de evanescencia mediante la interaccion del ente de union inmovilizado sobre el guiaondas de capa fina con las micotoxinas de la muestra y/o los entes de union; d) determinar la cantidad de micotoxina(s) presentes en la muestra. Reivindicacion 2: Procedimiento segun la reivindicacion 1, caracterizado porque se aplica sobre el guiaondas de capa fina monocapas o capas multiples de ácidos organofosforicos segun la siguiente formula (1): R-OPO3H2 y/o ácidos organofosforicos segun la siguiente formula (2) R-PO3H2 y/o sus sales, en donde R representa alquilo con C10 a C24.
ARP060105723A 2005-12-23 2006-12-21 Dispositivo y procedimiento para la deteccion de micotoxinas AR058616A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005062377A DE102005062377A1 (de) 2005-12-23 2005-12-23 Vorrichtung und Verfahren zum Nachweis von Mykotoxinen

Publications (1)

Publication Number Publication Date
AR058616A1 true AR058616A1 (es) 2008-02-13

Family

ID=37909504

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060105723A AR058616A1 (es) 2005-12-23 2006-12-21 Dispositivo y procedimiento para la deteccion de micotoxinas

Country Status (19)

Country Link
US (1) US20090081808A1 (es)
EP (1) EP1966594B1 (es)
JP (1) JP2009520956A (es)
KR (1) KR101232499B1 (es)
CN (1) CN101384896A (es)
AR (1) AR058616A1 (es)
AU (1) AU2006334802B2 (es)
BR (1) BRPI0620376A2 (es)
CA (1) CA2634559A1 (es)
CR (1) CR10087A (es)
DE (1) DE102005062377A1 (es)
DK (1) DK1966594T3 (es)
EA (1) EA013337B1 (es)
ES (1) ES2400919T3 (es)
PL (1) PL1966594T3 (es)
PT (1) PT1966594E (es)
UA (1) UA97792C2 (es)
WO (1) WO2007079893A1 (es)
ZA (1) ZA200805457B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130203613A1 (en) * 2009-04-09 2013-08-08 Bayer Cropscience Ag Device and method for the verification and quantitative analysis of analytes, particularly mycotoxins
DE102009016712A1 (de) 2009-04-09 2010-10-14 Bayer Technology Services Gmbh Einweg-Mikrofluidik-Testkassette zur Bioassay von Analyten
WO2011023230A1 (en) * 2009-08-27 2011-03-03 Foss Analytical Ab Method of extracting mycotoxins from cereal grains
CN101666752B (zh) * 2009-09-29 2011-07-20 济南大学 一种糖基功能化细菌毒素分子印迹柱的制备方法及应用
JP5840845B2 (ja) * 2011-02-25 2016-01-06 国立研究開発法人農業・食品産業技術総合研究機構 危害要因定量方法、危害要因定量装置、および、プログラム
ITMO20110109A1 (it) * 2011-05-11 2012-11-12 Generon S R L Metodo per l'analisi di aflatossine nel latte e nei derivati del latte
CN102279268A (zh) * 2011-07-29 2011-12-14 上海交通大学 同时检测玉米赤霉烯酮与伏马毒素的方法
CN102517290A (zh) * 2011-11-25 2012-06-27 国家纳米技术与工程研究院 伏马毒素b2核酸适体及其应用
CN102443585A (zh) * 2011-11-25 2012-05-09 国家纳米技术与工程研究院 玉米赤霉烯酮核酸适体及其应用
WO2013116847A1 (en) * 2012-02-03 2013-08-08 Charm Sciences, Inc. Extraction of mycotoxins
US20150292005A1 (en) * 2012-04-27 2015-10-15 Kirin Kabushiki Kaisha Nucleic acid molecules for highly sensitive detection of ligands, screening method for nucleic acid molecules, and optimization method for sensitivity of nucleic acid molecules
CN103743913B (zh) * 2014-01-23 2015-07-08 福建农林大学 快速鉴定与黄曲霉毒素b1互作的宿主蛋白的方法
CN104293793B (zh) * 2014-07-24 2018-05-18 江南大学 一种特异识别t-2毒素的寡核苷酸适配体
FR3028318A1 (fr) * 2014-11-12 2016-05-13 Phuong Lan Tran Procede et dispositif de tri selectif, specifique et simultane de cellules rares cibles dans un echantillon biologique
CN104593374B (zh) * 2015-03-02 2017-05-17 江南大学 一种特异识别棒曲霉素的寡核苷酸适配体
EP3294750B1 (en) * 2015-05-08 2023-10-25 Waters Technologies Corporation Composition and methods for extracting mycotoxins
KR102042661B1 (ko) * 2015-08-06 2019-11-08 광주과학기술원 타겟 물질 검출용 복합체 및 이를 이용한 타겟 물질 검출방법
DE202016106024U1 (de) 2016-10-26 2016-11-08 Matthias Godejohann Vorrichtung zur Halterung zu einer Halbleiterplatte
CN108614054A (zh) * 2016-12-12 2018-10-02 北京农学院 基于聚苯乙烯-二乙烯苯树脂为载体的真菌毒素免疫亲和柱的制备方法
CN108490169B (zh) * 2018-03-27 2021-09-03 广东一家人食品有限公司 一种米粉中真菌毒素的双水相萃取联合酶联免疫检测的方法
CN114051415A (zh) * 2019-07-03 2022-02-15 英特维特国际股份有限公司 防护霉菌毒素中毒的缀合脱氧雪腐镰刀菌烯醇
JP7387524B2 (ja) 2020-04-06 2023-11-28 Ｔｉａｎｍａ Ｊａｐａｎ株式会社 蛍光を用いた免疫分析法で測定するための試料溶液の調製方法、測定用セル、測定キットおよび試料溶液の調製装置

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208479A (en) * 1977-07-14 1980-06-17 Syva Company Label modified immunoassays
US5178832A (en) * 1987-09-28 1993-01-12 The Texas A&M University System Selective immobilization and detection of mycotoxins in solution
US5429952A (en) * 1988-02-02 1995-07-04 Biocode, Inc. Marking of products to establish identity and source
US5814565A (en) * 1995-02-23 1998-09-29 University Of Utah Research Foundation Integrated optic waveguide immunosensor
WO1999040415A1 (de) * 1998-02-05 1999-08-12 Novartis Ag Verfahren und vorrichtung zur lumineszenzmessung
US6743581B1 (en) * 1999-01-25 2004-06-01 Ut-Battelle, Lc Multifunctional and multispectral biosensor devices and methods of use
US7396675B2 (en) * 2000-06-02 2008-07-08 Bayer Technology Services Gmbh Kit and method for determining a plurality of analytes
DE50113602D1 (de) * 2000-09-05 2008-03-27 Bayer Technology Services Gmbh Verfahren zur abscheidung von mono- und mehrfachscd deren salzen sowie deren verwendung
US6812380B2 (en) * 2001-03-27 2004-11-02 Pioneer Hi-Bred International, Inc. Compositions and methods of zearalenone detoxification
JP4203826B2 (ja) * 2003-09-29 2009-01-07 独立行政法人産業技術総合研究所 自動分析方法及び装置
US20060210425A1 (en) * 2005-03-21 2006-09-21 Laura Mirkarimi Inorganic coatings for optical and other applications

Also Published As

Publication number Publication date
EA013337B1 (ru) 2010-04-30
PL1966594T3 (pl) 2013-06-28
WO2007079893A1 (de) 2007-07-19
EA200801588A1 (ru) 2008-12-30
DK1966594T3 (da) 2013-04-15
EP1966594A1 (de) 2008-09-10
BRPI0620376A2 (pt) 2011-11-08
AU2006334802B2 (en) 2013-03-14
KR20080083682A (ko) 2008-09-18
EP1966594B1 (de) 2013-01-23
AU2006334802A1 (en) 2007-07-19
CN101384896A (zh) 2009-03-11
KR101232499B1 (ko) 2013-02-12
CA2634559A1 (en) 2007-07-19
UA97792C2 (ru) 2012-03-26
PT1966594E (pt) 2013-03-13
US20090081808A1 (en) 2009-03-26
CR10087A (es) 2009-01-27
ZA200805457B (en) 2010-02-24
DE102005062377A1 (de) 2007-06-28
ES2400919T3 (es) 2013-04-15
JP2009520956A (ja) 2009-05-28

Similar Documents

Publication Publication Date Title
AR058616A1 (es) Dispositivo y procedimiento para la deteccion de micotoxinas
JP6594528B2 (ja) 蒸気凝縮液、特に呼気凝縮液を採取し分析する装置及びシステム、並びにそれらの使用方法
US10598600B2 (en) Optical sensor system
JP2009520956A5 (es)
WO2011005487A3 (en) Optical devices and methods for measuring samples
JP2017134089A5 (ja) センシング・システム
MX336061B (es) Metodos y sistemas para identificar contenido en una secuencia de datos.
ATE417906T1 (de) Haftklebemasse, haftklebefilm sowie optisches filter
ATE412171T1 (de) Faseroptische assay-vorrichtung auf der basis der phasenverschiebungs-interferometrie
WO2012170352A3 (en) Multiplex fluorescent particle detection using spatially distributed excitation
FR2968921B1 (fr) Procede de localisation d'un marqueur optique dans un milieu diffusant
AR053948A1 (es) Deteccion de un antigeno diana independientemente de la presencia o ausencia de un anticuerpo terapeutico correspondiente
JP2009139364A5 (es)
TW200630653A (en) Method and system for reading microarrays
PE20141069A1 (es) Marcadores de enfermedad tromboembolica
ATE522811T1 (de) Reagentien, kits und verfahren zum nachweis biologischer moleküle mittels energieübertragung von einem aktivierten chemilumineszenzsubstrat auf einen energieakzeptor-farbstoff
ATE538382T1 (de) Sequentieller optischer nachweis von einem array mit getrenntentestzonen
Prabowo et al. Performance of white organic light-emitting diode for portable optical biosensor
JP2012523549A5 (es)
AR076201A1 (es) Dispositivo y procedimiento para la deteccion y el analisis cuantitativo de analitos, particularmente de micotoxinas
AR093172A1 (es) Polimeros quimicamente marcados para la cuantificacion simplificada y metodos relacionados
JP2007514136A5 (es)
WO2007082160A3 (en) Method for increasing signal intensity in an optical waveguide sensor
BR112015029784A2 (pt) sistema, ferramenta de medição e método
GB201117623D0 (en) Fluorescence gas and liquid sensor

Legal Events

Date Code Title Description
FA Abandonment or withdrawal