AR053948A1 - Deteccion de un antigeno diana independientemente de la presencia o ausencia de un anticuerpo terapeutico correspondiente - Google Patents

Deteccion de un antigeno diana independientemente de la presencia o ausencia de un anticuerpo terapeutico correspondiente

Info

Publication number
AR053948A1
AR053948A1 ARP060102872A ARP060102872A AR053948A1 AR 053948 A1 AR053948 A1 AR 053948A1 AR P060102872 A ARP060102872 A AR P060102872A AR P060102872 A ARP060102872 A AR P060102872A AR 053948 A1 AR053948 A1 AR 053948A1
Authority
AR
Argentina
Prior art keywords
therapeutic antibody
diana
ancient
absence
independently
Prior art date
Application number
ARP060102872A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of AR053948A1 publication Critical patent/AR053948A1/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente está relacionada con el campo de los anticuerpos terapéuticos. La presente especialmente está relacionada con un método para la deteccion del antígeno diana de un anticuerpo terapéutico en una muestra que consiste en los siguientes pasos: a) proporcionar la muestra a analizar; b) incubar dicha muestra con dicho anticuerpo terapéutico bajo las condiciones apropiadas para unir dicho anticuerpo terapéutico a dicho antígeno diana, de manera que se forme un complejo de antígeno diana-anticuerpo terapéutico y c) detectar el complejo formado en b).
ARP060102872A 2005-07-06 2006-07-04 Deteccion de un antigeno diana independientemente de la presencia o ausencia de un anticuerpo terapeutico correspondiente AR053948A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05014618 2005-07-06
EP06004447 2006-03-06

Publications (1)

Publication Number Publication Date
AR053948A1 true AR053948A1 (es) 2007-05-23

Family

ID=36922121

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060102872A AR053948A1 (es) 2005-07-06 2006-07-04 Deteccion de un antigeno diana independientemente de la presencia o ausencia de un anticuerpo terapeutico correspondiente

Country Status (19)

Country Link
US (1) US20070009976A1 (es)
EP (2) EP2194380A3 (es)
JP (1) JP2008545145A (es)
KR (1) KR20080016939A (es)
AR (1) AR053948A1 (es)
AU (1) AU2006265275A1 (es)
BR (1) BRPI0612591A2 (es)
CA (1) CA2613187A1 (es)
CR (1) CR9635A (es)
EC (1) ECSP088081A (es)
IL (1) IL188317A0 (es)
MA (1) MA29730B1 (es)
MX (1) MX2008000277A (es)
MY (1) MY157955A (es)
NO (1) NO20076662L (es)
NZ (1) NZ564471A (es)
RU (1) RU2008103608A (es)
TW (1) TWI312864B (es)
WO (1) WO2007003420A1 (es)

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Publication number Priority date Publication date Assignee Title
ATE441433T1 (de) 2000-05-19 2009-09-15 Genentech Inc Gennachweisverfahren zur verbesserung der wahrscheinlichkeit einer wirkungsvollen antwort auf eine krebstherapie mit einem erbb- antagonisten
KR20070038557A (ko) * 2004-07-22 2007-04-10 제넨테크, 인크. Ｈｅｒ２ 항체 조성물
WO2006039486A2 (en) 2004-10-01 2006-04-13 The Board Of Trustees Of The Leland Stanford Junior University Imaging arrangements and methods therefor
JO3000B1 (ar) * 2004-10-20 2016-09-05 Genentech Inc مركبات أجسام مضادة .
EP1850874B1 (en) 2005-02-23 2013-10-16 Genentech, Inc. Extending time to disease progression or survival in ovarian cancer patients using pertuzumab
PE20070207A1 (es) * 2005-07-22 2007-03-09 Genentech Inc Tratamiento combinado de los tumores que expresan el her
US8358354B2 (en) 2009-01-26 2013-01-22 The Board Of Trustees Of The Leland Stanford Junior University Correction of optical abberations
US8243157B2 (en) 2006-02-07 2012-08-14 The Board Of Trustees Of The Leland Stanford Junior University Correction of optical aberrations
MX2009008981A (es) 2007-03-02 2009-09-02 Genentech Inc Prediccion de respuesta a un inhibidor her.
TWI472339B (zh) 2008-01-30 2015-02-11 Genentech Inc 包含結合至ｈｅｒ２結構域ii之抗體及其酸性變異體的組合物
BRPI0812682A2 (pt) 2008-06-16 2010-06-22 Genentech Inc tratamento de cáncer de mama metastático
DK2766040T3 (da) 2011-10-14 2019-07-22 Hoffmann La Roche Pertuzumab, trastuzumab, docetaxel og carboplatin til behandling af brystkræft i et tidligt stadie
KR101327542B1 (ko) * 2012-03-15 2013-11-08 광주과학기술원 양자점 기반의 경쟁 면역분석법 및 다중 유세포 분석법을 이용한 시료 중 오염물질의 검출 방법
AU2012232949B2 (en) * 2012-09-28 2014-07-03 Willowtree Holdings Pty Ltd Temporary bulkhead
BR112015024926A2 (pt) 2013-04-16 2017-10-10 Genentech Inc composições, artigo de fabricação, métodos para tratar um paciente com câncer, para avaliar uma composição, para avaliar a atividade biológica, para produzir uma composição e para avaliar a fragmentação de uma composição e variante de pertuzumabe
SG10201809411PA (en) 2014-04-25 2018-11-29 Genentech Inc Methods of treating early breast cancer with trastuzumab-mcc-dm1 and pertuzumab
CN107614015A (zh) 2015-05-30 2018-01-19 豪夫迈·罗氏有限公司 治疗her2阳性局部晚期或先前未治疗的转移性乳腺癌的方法
WO2017087280A1 (en) 2015-11-16 2017-05-26 Genentech, Inc. Methods of treating her2-positive cancer
EP3562844A1 (en) 2016-12-28 2019-11-06 Genentech, Inc. Treatment of advanced her2 expressing cancer
EP3570884B1 (en) 2017-01-17 2020-09-30 Genentech, Inc. Subcutaneous her2 antibody formulations
WO2018160654A2 (en) 2017-03-02 2018-09-07 Genentech, Inc. Adjuvant treatment of her2-positive breast cancer
EP3615695A1 (en) 2017-04-24 2020-03-04 Genentech, Inc. Erbb2/her2 mutations in the transmebrane or juxtamembrane domain

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2095818B (en) 1981-03-27 1985-10-02 Exxon Research Engineering Co Staged adsorption/resorption heat pump
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
EP1400536A1 (en) * 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
WO1993021319A1 (en) 1992-04-08 1993-10-28 Cetus Oncology Corporation HUMANIZED C-erbB-2 SPECIFIC ANTIBODIES
AU4982097A (en) 1996-10-18 1998-05-15 Board Of Regents, The University Of Texas System Anti-erbb2 antibodies
ATE443259T1 (de) * 2001-09-20 2009-10-15 Univ Texas Bestimmung der zirkulierenden therapeutischen antikörper, antigene sowie antigen-antikörper- komplexe mit elisa-tests
HUP0600340A3 (en) * 2002-07-15 2011-06-28 Genentech Inc Methods for identifying tumors that are responsive to treatment with anti-erbb2 antibodies

Also Published As

Publication number Publication date
US20070009976A1 (en) 2007-01-11
ECSP088081A (es) 2008-02-20
TW200741203A (en) 2007-11-01
RU2008103608A (ru) 2009-08-20
MX2008000277A (es) 2008-03-24
TWI312864B (en) 2009-08-01
EP2194380A3 (en) 2010-07-14
MA29730B1 (fr) 2008-09-01
BRPI0612591A2 (pt) 2010-11-23
KR20080016939A (ko) 2008-02-22
IL188317A0 (en) 2008-04-13
MY157955A (en) 2016-08-30
NO20076662L (no) 2008-04-03
EP2194380A2 (en) 2010-06-09
JP2008545145A (ja) 2008-12-11
WO2007003420A1 (en) 2007-01-11
EP1902315A1 (en) 2008-03-26
AU2006265275A1 (en) 2007-01-11
CA2613187A1 (en) 2007-01-11
CR9635A (es) 2008-02-20
NZ564471A (en) 2010-04-30

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