NO20076662L - Deteksjon av et malantigen uavhengig av tilstedevaerelse eller fravaer av et korresponderende terapeutisk antistoff - Google Patents

Deteksjon av et malantigen uavhengig av tilstedevaerelse eller fravaer av et korresponderende terapeutisk antistoff

Info

Publication number
NO20076662L
NO20076662L NO20076662A NO20076662A NO20076662L NO 20076662 L NO20076662 L NO 20076662L NO 20076662 A NO20076662 A NO 20076662A NO 20076662 A NO20076662 A NO 20076662A NO 20076662 L NO20076662 L NO 20076662L
Authority
NO
Norway
Prior art keywords
therapeutic antibody
malantigen
absence
independent
detection
Prior art date
Application number
NO20076662A
Other languages
English (en)
Inventor
Helmut Lenz
Werner Scheuer
Martina Thier
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20076662L publication Critical patent/NO20076662L/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase

Abstract

Foreliggende oppfinnelse angår området terapeutiske antistoffer. Oppfinnelsen angår spesielt en metode for detektering av målantigenet av et terapeutisk antistoff i en prøve omfattende trinnene med a) tilveiebringelse av prøven som skal analyseres, b) inkubering av nevnte prøve med nevnte terapeutiske antistoff under betingelser egnet for binding av nevnte terapeutiske antistoff til nevnte målantigen, hvorved et målantigen-terapeutisk antistoff-kompleks blir dannet og c) detektering av komplekset dannet i (b).
NO20076662A 2005-07-06 2007-12-28 Deteksjon av et malantigen uavhengig av tilstedevaerelse eller fravaer av et korresponderende terapeutisk antistoff NO20076662L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05014618 2005-07-06
EP06004447 2006-03-06
PCT/EP2006/006524 WO2007003420A1 (en) 2005-07-06 2006-07-05 Detection of a target antigen irrespective of the presence or absence of a corresponding therapeutic antibody

Publications (1)

Publication Number Publication Date
NO20076662L true NO20076662L (no) 2008-04-03

Family

ID=36922121

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20076662A NO20076662L (no) 2005-07-06 2007-12-28 Deteksjon av et malantigen uavhengig av tilstedevaerelse eller fravaer av et korresponderende terapeutisk antistoff

Country Status (19)

Country Link
US (1) US20070009976A1 (no)
EP (2) EP1902315A1 (no)
JP (1) JP2008545145A (no)
KR (1) KR20080016939A (no)
AR (1) AR053948A1 (no)
AU (1) AU2006265275A1 (no)
BR (1) BRPI0612591A2 (no)
CA (1) CA2613187A1 (no)
CR (1) CR9635A (no)
EC (1) ECSP088081A (no)
IL (1) IL188317A0 (no)
MA (1) MA29730B1 (no)
MX (1) MX2008000277A (no)
MY (1) MY157955A (no)
NO (1) NO20076662L (no)
NZ (1) NZ564471A (no)
RU (1) RU2008103608A (no)
TW (1) TWI312864B (no)
WO (1) WO2007003420A1 (no)

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CN102698265A (zh) * 2000-05-19 2012-10-03 杰南技术公司 用于提高对ErbB 拮抗剂癌症治疗的有效应答可能性的基因检测试验
KR20160096228A (ko) 2004-07-22 2016-08-12 제넨테크, 인크. Ｈｅｒ２ 항체 조성물
KR101134208B1 (ko) 2004-10-01 2012-04-09 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 촬상 장치 및 그 방법
JO3000B1 (ar) * 2004-10-20 2016-09-05 Genentech Inc مركبات أجسام مضادة .
AU2006216732C1 (en) 2005-02-23 2017-07-20 Genentech, Inc. Extending time to disease progression or survival in cancer patients using a HER dimerization inhibitor
PE20070207A1 (es) * 2005-07-22 2007-03-09 Genentech Inc Tratamiento combinado de los tumores que expresan el her
WO2007092581A2 (en) 2006-02-07 2007-08-16 The Board Of Trustees Of The Leland Stanford Junior University Correction of optical aberrations
US8358354B2 (en) 2009-01-26 2013-01-22 The Board Of Trustees Of The Leland Stanford Junior University Correction of optical abberations
WO2008109440A2 (en) 2007-03-02 2008-09-12 Genentech, Inc. Predicting response to a her dimerisation inhibitor based on low her3 expression
TWI472339B (zh) 2008-01-30 2015-02-11 Genentech Inc 包含結合至ｈｅｒ２結構域ii之抗體及其酸性變異體的組合物
BRPI0812682A2 (pt) 2008-06-16 2010-06-22 Genentech Inc tratamento de cáncer de mama metastático
DK2766040T3 (da) 2011-10-14 2019-07-22 Hoffmann La Roche Pertuzumab, trastuzumab, docetaxel og carboplatin til behandling af brystkræft i et tidligt stadie
KR101327542B1 (ko) * 2012-03-15 2013-11-08 광주과학기술원 양자점 기반의 경쟁 면역분석법 및 다중 유세포 분석법을 이용한 시료 중 오염물질의 검출 방법
AU2012232949B2 (en) * 2012-09-28 2014-07-03 Willowtree Holdings Pty Ltd Temporary bulkhead
AR095863A1 (es) 2013-04-16 2015-11-18 Genentech Inc Variantes de pertuzumab, su evaluación, método de tratamiento, método de preparación y artículo de fabricación
EP3134440A1 (en) 2014-04-25 2017-03-01 F. Hoffmann-La Roche AG Methods of treating early breast cancer with trastuzumab-mcc-dm1 and pertuzumab
EP3302551A2 (en) 2015-05-30 2018-04-11 H. Hoffnabb-La Roche Ag Methods of treating her2-positive locally advanced or previously untreated metastatic breast cancer
WO2017087280A1 (en) 2015-11-16 2017-05-26 Genentech, Inc. Methods of treating her2-positive cancer
CN110099926A (zh) 2016-12-28 2019-08-06 豪夫迈·罗氏有限公司 晚期her2表达性癌症的治疗
RU2750821C2 (ru) 2017-01-17 2021-07-05 Дженентек, Инк. Препараты антител против her2 для подкожного введения
FI3589661T3 (fi) 2017-03-02 2024-01-31 Genentech Inc Her2-positiivisen rintasyövän adjuvanttihoito
CN110536969A (zh) 2017-04-24 2019-12-03 豪夫迈·罗氏有限公司 跨膜或近膜域中的erbb2/her2突变

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
GB2095818B (en) 1981-03-27 1985-10-02 Exxon Research Engineering Co Staged adsorption/resorption heat pump
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
ES2206447T3 (es) * 1991-06-14 2004-05-16 Genentech, Inc. Anticuerpo humanizado para heregulina.
AU4025193A (en) 1992-04-08 1993-11-18 Cetus Oncology Corporation Humanized C-erbB-2 specific antibodies
NZ519191A (en) 1996-10-18 2005-04-29 Univ Texas Antibodies that bind to domain 1 of ErbB2 useful for inducing cell death via apoptosis, and nucleic acids encoding such antibodies
EP2131198B1 (en) * 2001-09-20 2013-03-27 Board of Regents, The University of Texas System Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using ELISA assays
PT1585966E (pt) * 2002-07-15 2012-02-20 Hoffmann La Roche Tratamento de cancro com o anticorpo anti-erbb2 rhumab 2c4

Also Published As

Publication number Publication date
MA29730B1 (fr) 2008-09-01
AR053948A1 (es) 2007-05-23
AU2006265275A1 (en) 2007-01-11
ECSP088081A (es) 2008-02-20
TW200741203A (en) 2007-11-01
CA2613187A1 (en) 2007-01-11
BRPI0612591A2 (pt) 2010-11-23
MY157955A (en) 2016-08-30
EP1902315A1 (en) 2008-03-26
NZ564471A (en) 2010-04-30
TWI312864B (en) 2009-08-01
EP2194380A3 (en) 2010-07-14
CR9635A (es) 2008-02-20
WO2007003420A1 (en) 2007-01-11
JP2008545145A (ja) 2008-12-11
EP2194380A2 (en) 2010-06-09
RU2008103608A (ru) 2009-08-20
US20070009976A1 (en) 2007-01-11
KR20080016939A (ko) 2008-02-22
IL188317A0 (en) 2008-04-13
MX2008000277A (es) 2008-03-24

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