TWI312864B - Detection of a target antigen irrespective of the presence or absence of a corresponding therapeutic antibody - Google Patents
Detection of a target antigen irrespective of the presence or absence of a corresponding therapeutic antibody Download PDFInfo
- Publication number
- TWI312864B TWI312864B TW095124248A TW95124248A TWI312864B TW I312864 B TWI312864 B TW I312864B TW 095124248 A TW095124248 A TW 095124248A TW 95124248 A TW95124248 A TW 95124248A TW I312864 B TWI312864 B TW I312864B
- Authority
- TW
- Taiwan
- Prior art keywords
- absence
- detection
- target antigen
- therapeutic antibody
- corresponding therapeutic
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05014618 | 2005-07-06 | ||
EP06004447 | 2006-03-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
TW200741203A TW200741203A (en) | 2007-11-01 |
TWI312864B true TWI312864B (en) | 2009-08-01 |
Family
ID=36922121
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW095124248A TWI312864B (en) | 2005-07-06 | 2006-07-04 | Detection of a target antigen irrespective of the presence or absence of a corresponding therapeutic antibody |
Country Status (19)
Country | Link |
---|---|
US (1) | US20070009976A1 (zh) |
EP (2) | EP1902315A1 (zh) |
JP (1) | JP2008545145A (zh) |
KR (1) | KR20080016939A (zh) |
AR (1) | AR053948A1 (zh) |
AU (1) | AU2006265275A1 (zh) |
BR (1) | BRPI0612591A2 (zh) |
CA (1) | CA2613187A1 (zh) |
CR (1) | CR9635A (zh) |
EC (1) | ECSP088081A (zh) |
IL (1) | IL188317A0 (zh) |
MA (1) | MA29730B1 (zh) |
MX (1) | MX2008000277A (zh) |
MY (1) | MY157955A (zh) |
NO (1) | NO20076662L (zh) |
NZ (1) | NZ564471A (zh) |
RU (1) | RU2008103608A (zh) |
TW (1) | TWI312864B (zh) |
WO (1) | WO2007003420A1 (zh) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030007640A (ko) | 2000-05-19 | 2003-01-23 | 제넨테크, 인크. | ErbB 길항제에 의한 암 치료요법에 대한 효과적인반응의 가능성을 개선시키기 위한 유전자 검출 분석 |
BRPI0513681A (pt) * | 2004-07-22 | 2008-05-13 | Genentech Inc | composição que compreendem anticorpo her2, método, formulações farmacêuticas, polipeptìdeo, anticorpo e método de tratamento de cáncer |
WO2006039486A2 (en) | 2004-10-01 | 2006-04-13 | The Board Of Trustees Of The Leland Stanford Junior University | Imaging arrangements and methods therefor |
JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
RU2404806C2 (ru) | 2005-02-23 | 2010-11-27 | Дженентек, Инк. | Продление времени до прогрессирования заболевания или продолжительности жизни у онкологических больных с применением ингибиторов димеризации her |
PE20070207A1 (es) * | 2005-07-22 | 2007-03-09 | Genentech Inc | Tratamiento combinado de los tumores que expresan el her |
US8248515B2 (en) | 2006-02-07 | 2012-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | Variable imaging arrangements and methods therefor |
US8358354B2 (en) | 2009-01-26 | 2013-01-22 | The Board Of Trustees Of The Leland Stanford Junior University | Correction of optical abberations |
CL2008000614A1 (es) | 2007-03-02 | 2008-09-05 | Genentech Inc F Hoffmann La Ro | Metodo para tratar un paciente con un tipo de cancer que expresa el receptor her3 a un nivel bajo mediante la administracion de un inhibidor de la dimerizacion de her. |
TWI472339B (zh) | 2008-01-30 | 2015-02-11 | Genentech Inc | 包含結合至her2結構域ii之抗體及其酸性變異體的組合物 |
BRPI0812682A2 (pt) | 2008-06-16 | 2010-06-22 | Genentech Inc | tratamento de cáncer de mama metastático |
CN117018187A (zh) | 2011-10-14 | 2023-11-10 | 霍夫曼-拉罗奇有限公司 | Her2二聚化抑制剂帕妥珠单抗的用途和包含her2二聚化抑制剂帕妥珠单抗的制品 |
KR101327542B1 (ko) * | 2012-03-15 | 2013-11-08 | 광주과학기술원 | 양자점 기반의 경쟁 면역분석법 및 다중 유세포 분석법을 이용한 시료 중 오염물질의 검출 방법 |
AU2012232949B2 (en) * | 2012-09-28 | 2014-07-03 | Willowtree Holdings Pty Ltd | Temporary bulkhead |
BR112015024926A2 (pt) | 2013-04-16 | 2017-10-10 | Genentech Inc | composições, artigo de fabricação, métodos para tratar um paciente com câncer, para avaliar uma composição, para avaliar a atividade biológica, para produzir uma composição e para avaliar a fragmentação de uma composição e variante de pertuzumabe |
CN106163558A (zh) | 2014-04-25 | 2016-11-23 | 豪夫迈·罗氏有限公司 | 用曲妥珠单抗‑mcc‑dm1和帕妥珠单抗治疗早期乳腺癌的方法 |
WO2016196373A2 (en) | 2015-05-30 | 2016-12-08 | Genentech, Inc. | Methods of treating her2-positive metastatic breast cancer |
WO2017087280A1 (en) | 2015-11-16 | 2017-05-26 | Genentech, Inc. | Methods of treating her2-positive cancer |
CA3046092A1 (en) | 2016-12-28 | 2018-07-05 | Genentech, Inc. | Treatment of advanced her2 expressing cancer |
KR20200113292A (ko) | 2017-01-17 | 2020-10-06 | 제넨테크, 인크. | 피하 her2 항체 제형 |
US11077189B2 (en) | 2017-03-02 | 2021-08-03 | Genentech Inc. | Adjuvant treatment of HER2-positive breast cancer |
CN110536969A (zh) | 2017-04-24 | 2019-12-03 | 豪夫迈·罗氏有限公司 | 跨膜或近膜域中的erbb2/her2突变 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2095818B (en) | 1981-03-27 | 1985-10-02 | Exxon Research Engineering Co | Staged adsorption/resorption heat pump |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
ATE255131T1 (de) * | 1991-06-14 | 2003-12-15 | Genentech Inc | Humanisierter heregulin antikörper |
AU4025193A (en) | 1992-04-08 | 1993-11-18 | Cetus Oncology Corporation | Humanized C-erbB-2 specific antibodies |
IL129354A0 (en) | 1996-10-18 | 2000-02-17 | Genentech Inc | Anti-ErbB2 antibodies |
EP2131198B1 (en) | 2001-09-20 | 2013-03-27 | Board of Regents, The University of Texas System | Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using ELISA assays |
PT1585966E (pt) * | 2002-07-15 | 2012-02-20 | Hoffmann La Roche | Tratamento de cancro com o anticorpo anti-erbb2 rhumab 2c4 |
-
2006
- 2006-06-29 MY MYPI20063118A patent/MY157955A/en unknown
- 2006-06-29 US US11/477,772 patent/US20070009976A1/en not_active Abandoned
- 2006-07-04 AR ARP060102872A patent/AR053948A1/es not_active Application Discontinuation
- 2006-07-04 TW TW095124248A patent/TWI312864B/zh active
- 2006-07-05 WO PCT/EP2006/006524 patent/WO2007003420A1/en active Application Filing
- 2006-07-05 CA CA002613187A patent/CA2613187A1/en not_active Abandoned
- 2006-07-05 MX MX2008000277A patent/MX2008000277A/es not_active Application Discontinuation
- 2006-07-05 KR KR1020087000259A patent/KR20080016939A/ko active Search and Examination
- 2006-07-05 BR BRPI0612591-3A patent/BRPI0612591A2/pt not_active IP Right Cessation
- 2006-07-05 JP JP2008519853A patent/JP2008545145A/ja active Pending
- 2006-07-05 EP EP06754671A patent/EP1902315A1/en not_active Withdrawn
- 2006-07-05 NZ NZ564471A patent/NZ564471A/en unknown
- 2006-07-05 RU RU2008103608/15A patent/RU2008103608A/ru unknown
- 2006-07-05 AU AU2006265275A patent/AU2006265275A1/en not_active Abandoned
- 2006-07-05 EP EP10157725A patent/EP2194380A3/en not_active Withdrawn
-
2007
- 2007-12-20 IL IL188317A patent/IL188317A0/en unknown
- 2007-12-21 CR CR9635A patent/CR9635A/es not_active Application Discontinuation
- 2007-12-28 NO NO20076662A patent/NO20076662L/no not_active Application Discontinuation
-
2008
- 2008-01-04 EC EC2008008081A patent/ECSP088081A/es unknown
- 2008-02-01 MA MA30617A patent/MA29730B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
AU2006265275A1 (en) | 2007-01-11 |
RU2008103608A (ru) | 2009-08-20 |
NO20076662L (no) | 2008-04-03 |
EP2194380A3 (en) | 2010-07-14 |
EP1902315A1 (en) | 2008-03-26 |
KR20080016939A (ko) | 2008-02-22 |
CR9635A (es) | 2008-02-20 |
IL188317A0 (en) | 2008-04-13 |
MA29730B1 (fr) | 2008-09-01 |
JP2008545145A (ja) | 2008-12-11 |
MX2008000277A (es) | 2008-03-24 |
US20070009976A1 (en) | 2007-01-11 |
BRPI0612591A2 (pt) | 2010-11-23 |
EP2194380A2 (en) | 2010-06-09 |
NZ564471A (en) | 2010-04-30 |
TW200741203A (en) | 2007-11-01 |
WO2007003420A1 (en) | 2007-01-11 |
AR053948A1 (es) | 2007-05-23 |
ECSP088081A (es) | 2008-02-20 |
CA2613187A1 (en) | 2007-01-11 |
MY157955A (en) | 2016-08-30 |
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