WO2007024735A3 - Method and antibodies for detecting nitrofuran - Google Patents

Method and antibodies for detecting nitrofuran Download PDF

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Publication number
WO2007024735A3
WO2007024735A3 PCT/US2006/032443 US2006032443W WO2007024735A3 WO 2007024735 A3 WO2007024735 A3 WO 2007024735A3 US 2006032443 W US2006032443 W US 2006032443W WO 2007024735 A3 WO2007024735 A3 WO 2007024735A3
Authority
WO
WIPO (PCT)
Prior art keywords
nitrofuran
antibodies
metabolites
antibody
detected
Prior art date
Application number
PCT/US2006/032443
Other languages
French (fr)
Other versions
WO2007024735A2 (en
Inventor
Say-Jong Law
Steven J Saul
Stanley E Charm
Original Assignee
Charm Sciences Inc
Say-Jong Law
Steven J Saul
Stanley E Charm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Charm Sciences Inc, Say-Jong Law, Steven J Saul, Stanley E Charm filed Critical Charm Sciences Inc
Priority to EP06801912A priority Critical patent/EP1945664A2/en
Priority to US11/583,236 priority patent/US7632928B2/en
Publication of WO2007024735A2 publication Critical patent/WO2007024735A2/en
Publication of WO2007024735A3 publication Critical patent/WO2007024735A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9446—Antibacterials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids

Abstract

An antibody and immunogen for generating an antibody to nitrofuran and/or nitrofuran metabolite such as tissue or protein bound nitrofuran metabolites. Nitrofurans and and/or nitrofuran metabolites in a biological sample can be detected by contacting the sample with the antibodies to form a complex that can be detected. The antibodies may also be incorporated into test kits for the detection of nitrofuran and/or nitrofuran metabolites.
PCT/US2006/032443 2004-04-19 2006-08-21 Method and antibodies for detecting nitrofuran WO2007024735A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP06801912A EP1945664A2 (en) 2005-08-19 2006-08-21 Method and antibodies for detecting nitrofuran
US11/583,236 US7632928B2 (en) 2004-04-19 2006-10-18 Method and antibodies for detecting nitrofuran

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71002605P 2005-08-19 2005-08-19
US60/710,026 2005-08-19

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/012898 Continuation-In-Part WO2005103698A2 (en) 2004-04-19 2005-04-15 Methods and antibodies for nitrofuran detection

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/583,236 Continuation US7632928B2 (en) 2004-04-19 2006-10-18 Method and antibodies for detecting nitrofuran

Publications (2)

Publication Number Publication Date
WO2007024735A2 WO2007024735A2 (en) 2007-03-01
WO2007024735A3 true WO2007024735A3 (en) 2007-11-01

Family

ID=37772234

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/032443 WO2007024735A2 (en) 2004-04-19 2006-08-21 Method and antibodies for detecting nitrofuran

Country Status (2)

Country Link
EP (1) EP1945664A2 (en)
WO (1) WO2007024735A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102721805A (en) * 2011-03-29 2012-10-10 宝瑞源生物技术(北京)有限公司 3-amino-5-morpholinomethyl-2-oxazolidinone(AMOZ) assay kit and method for making the same

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2306626B1 (en) * 2008-05-23 2009-10-15 Centro Tecnologico Nacional De La Conserva Y Alimentacion (Ctc) SYSTEM FOR THE DETECTION OF ANTIBIOTICS IN FOOD.
CN101957375B (en) * 2010-10-15 2013-03-20 扬州大学 Preparation method of label-free impedance type immunosensor for furaltadone residues and application thereof
CN102565403A (en) * 2010-12-16 2012-07-11 北京勤邦生物技术有限公司 Magnetic particle chemiluminescence kit for detecting furaltadone and application thereof
CN102621326B (en) * 2012-02-23 2014-08-06 苏州大学 Method for detecting furaltadone metabolite content in food
CN103364557B (en) * 2012-04-07 2016-02-24 北京勤邦生物技术有限公司 A kind of kit and method detecting AMOZ
CN103105488B (en) * 2012-12-31 2016-03-30 戴信敏 A kind of semicarbazides (SEM) derivatization reagent and using method thereof
GB201322538D0 (en) 2013-06-21 2014-02-05 Immusmol Sas Method for detecting small molecules in a sample
CN104237499A (en) * 2014-09-13 2014-12-24 佛山市质量计量监督检测中心 Preparation of immunizing antigens and envelope antigens for detecting furazolidone metabolites
CN108047156B (en) * 2017-12-26 2020-08-07 华南农业大学 5-methylmorpholine-3-amino-2-oxazolidinyl ketone antigen with spiro structure, antibody, preparation and application
CN108129412B (en) * 2017-12-26 2020-08-07 华南农业大学 5-methylmorpholine-3-amino-2-oxazolidinyl ketone antigen, antibody, preparation and application
CN109097338A (en) 2018-08-09 2018-12-28 江南大学 A kind of hybridoma cell strain of secretion nifursol residual marker monoclonal antibody

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5086068A (en) * 1988-02-26 1992-02-04 Alberta Cancer Board Immunochemical detection of hypoxia in normal and tumor tissue

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5086068A (en) * 1988-02-26 1992-02-04 Alberta Cancer Board Immunochemical detection of hypoxia in normal and tumor tissue

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
COOPER ET AL.: "Production and characterization of polyclonal antibodies to a derivative of 3-amino-2-oxazolidinone, a metabolite of the nitrofuran furazolidone", ANALYTICA CHIMICA ACTA, vol. 520, no. 1-2, 2004, pages 79 - 86, XP004543633 *
KOTKOVA ET AL.: "Production and characterization of monoclonal antibodies for the detection of AOZ", A TISSUE BOUND METABOLITE OF FURAZOLIDONE, XP002995939 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102721805A (en) * 2011-03-29 2012-10-10 宝瑞源生物技术(北京)有限公司 3-amino-5-morpholinomethyl-2-oxazolidinone(AMOZ) assay kit and method for making the same

Also Published As

Publication number Publication date
WO2007024735A2 (en) 2007-03-01
EP1945664A2 (en) 2008-07-23

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