JP2004501054A5 - - Google Patents
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- Publication number
- JP2004501054A5 JP2004501054A5 JP2000524296A JP2000524296A JP2004501054A5 JP 2004501054 A5 JP2004501054 A5 JP 2004501054A5 JP 2000524296 A JP2000524296 A JP 2000524296A JP 2000524296 A JP2000524296 A JP 2000524296A JP 2004501054 A5 JP2004501054 A5 JP 2004501054A5
- Authority
- JP
- Japan
- Prior art keywords
- solid phase
- method described
- nucleic acid
- blood sample
- nucleic acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 description 32
- 239000007790 solid phase Substances 0.000 description 19
- 239000002253 acid Substances 0.000 description 9
- 150000007523 nucleic acids Chemical class 0.000 description 9
- 102000039446 nucleic acids Human genes 0.000 description 9
- 108020004707 nucleic acids Proteins 0.000 description 9
- 239000008280 blood Substances 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 7
- 239000004033 plastic Substances 0.000 description 6
- 239000000463 material Substances 0.000 description 5
- 239000012620 biological material Substances 0.000 description 3
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 239000004743 Polypropylene Substances 0.000 description 2
- 239000011324 bead Substances 0.000 description 2
- 239000000872 buffer Substances 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 239000003456 ion exchange resin Substances 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- -1 polypropylene Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 239000011343 solid material Substances 0.000 description 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 1
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 238000005349 anion exchange Methods 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 230000003196 chaotropic effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 239000005289 controlled pore glass Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 125000000524 functional group Chemical group 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 description 1
- 239000000815 hypotonic solution Substances 0.000 description 1
- 125000002883 imidazolyl group Chemical group 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 229920003303 ion-exchange polymer Polymers 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000005298 paramagnetic effect Effects 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920002704 polyhistidine Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9725839.6A GB9725839D0 (en) | 1997-12-06 | 1997-12-06 | Isolation of nucleic acids |
| GBGB9815541.9A GB9815541D0 (en) | 1998-07-17 | 1998-07-17 | Isolation of nucleic acids |
| PCT/GB1998/003602 WO1999029703A2 (en) | 1997-12-06 | 1998-12-04 | Isolation of nucleic acids |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010050067A Division JP2010162037A (ja) | 1997-12-06 | 2010-03-08 | 核酸の単離 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004501054A JP2004501054A (ja) | 2004-01-15 |
| JP2004501054A5 true JP2004501054A5 (enExample) | 2006-01-05 |
Family
ID=26312726
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000524296A Pending JP2004501054A (ja) | 1997-12-06 | 1998-12-04 | 核酸の単離 |
| JP2010050067A Pending JP2010162037A (ja) | 1997-12-06 | 2010-03-08 | 核酸の単離 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010050067A Pending JP2010162037A (ja) | 1997-12-06 | 2010-03-08 | 核酸の単離 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20030130499A1 (enExample) |
| EP (2) | EP1234832B1 (enExample) |
| JP (2) | JP2004501054A (enExample) |
| KR (2) | KR20050088164A (enExample) |
| CN (1) | CN1230440C (enExample) |
| AT (2) | ATE218140T1 (enExample) |
| AU (1) | AU755342B2 (enExample) |
| BR (1) | BR9815569A (enExample) |
| CA (1) | CA2318306A1 (enExample) |
| DE (2) | DE69805649T2 (enExample) |
| DK (1) | DK1036082T3 (enExample) |
| ES (2) | ES2177093T3 (enExample) |
| NO (1) | NO315323B1 (enExample) |
| PT (1) | PT1036082E (enExample) |
| WO (1) | WO1999029703A2 (enExample) |
Families Citing this family (116)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9425138D0 (en) | 1994-12-12 | 1995-02-08 | Dynal As | Isolation of nucleic acid |
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| JP2002541839A (ja) * | 1999-04-21 | 2002-12-10 | アノビス， インコーポレイテッド | 植物についての磁気ｄｎａ抽出キット |
| US6383783B1 (en) * | 1999-09-21 | 2002-05-07 | 3M Innovative Properties Company | Nucleic acid isolation by adhering to hydrophobic solid phase and removing with nonionic surfactant |
| SE9904539D0 (sv) * | 1999-12-10 | 1999-12-10 | Alphahelix Ab | Method and device for the handling of samples and reagents |
| JP2001221721A (ja) * | 2000-02-09 | 2001-08-17 | Sapporo Imuno Diagnostic Laboratory:Kk | 乾燥濾紙便による遺伝子診断 |
| DE10006590B4 (de) * | 2000-02-11 | 2007-10-18 | Qiagen North American Holdings, Inc. | Verwendung funktionalisierter Membranen bzw. Matrizes zur Aufreinigung von Nukleinsäuren sowie entsprechende Verfahren |
| US20020106686A1 (en) * | 2001-01-09 | 2002-08-08 | Mckernan Kevin J. | Methods and reagents for the isolation of nucleic acids |
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| GB0212825D0 (en) * | 2002-05-31 | 2002-07-10 | Dna Res Innovations Ltd | Methods compositions and kits for cell separation |
| GB0212826D0 (en) * | 2002-05-31 | 2002-07-10 | Dna Res Innovations Ltd | Materials and methods relating to polyions and substance delivery |
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1998
- 1998-12-04 CN CNB988118939A patent/CN1230440C/zh not_active Expired - Lifetime
- 1998-12-04 ES ES98957019T patent/ES2177093T3/es not_active Expired - Lifetime
- 1998-12-04 JP JP2000524296A patent/JP2004501054A/ja active Pending
- 1998-12-04 DE DE69805649T patent/DE69805649T2/de not_active Expired - Lifetime
- 1998-12-04 DE DE69839133T patent/DE69839133T2/de not_active Expired - Lifetime
- 1998-12-04 EP EP02003403A patent/EP1234832B1/en not_active Revoked
- 1998-12-04 WO PCT/GB1998/003602 patent/WO1999029703A2/en not_active Ceased
- 1998-12-04 PT PT98957019T patent/PT1036082E/pt unknown
- 1998-12-04 CA CA002318306A patent/CA2318306A1/en not_active Abandoned
- 1998-12-04 AT AT98957019T patent/ATE218140T1/de not_active IP Right Cessation
- 1998-12-04 EP EP98957019A patent/EP1036082B1/en not_active Expired - Lifetime
- 1998-12-04 KR KR1020057014820A patent/KR20050088164A/ko not_active Ceased
- 1998-12-04 AU AU13447/99A patent/AU755342B2/en not_active Ceased
- 1998-12-04 ES ES02003403T patent/ES2301581T3/es not_active Expired - Lifetime
- 1998-12-04 KR KR1020007006123A patent/KR20010032806A/ko not_active Ceased
- 1998-12-04 AT AT02003403T patent/ATE386044T1/de not_active IP Right Cessation
- 1998-12-04 DK DK98957019T patent/DK1036082T3/da active
- 1998-12-04 BR BR9815569-5A patent/BR9815569A/pt not_active Application Discontinuation
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2000
- 2000-05-16 NO NO20002540A patent/NO315323B1/no unknown
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2002
- 2002-11-21 US US10/300,990 patent/US20030130499A1/en not_active Abandoned
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2010
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