JP2002533124A - Ｈｉｖポリペプチドの改善された発現およびウイルス様粒子の生成 - Google Patents

Ｈｉｖポリペプチドの改善された発現およびウイルス様粒子の生成

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Publication number
JP2002533124A
JP2002533124A JP2000591193A JP2000591193A JP2002533124A JP 2002533124 A JP2002533124 A JP 2002533124A JP 2000591193 A JP2000591193 A JP 2000591193A JP 2000591193 A JP2000591193 A JP 2000591193A JP 2002533124 A JP2002533124 A JP 2002533124A
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Prior art keywords
seq
expression cassette
polypeptide
sequence
expression
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Pending
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JP2000591193A
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Japanese (ja)
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JP2002533124A5 (enExample
Inventor
スーザン バーネット，
ジャン ザーメジェド，
インドレッシュ スリバスタバ，
イャン リアン，
カリン ハートッグ，
ホン リュー，
キャサリーン グリーア，
マーク セルビー，
クリストファー ウォーカー，
Original Assignee
カイロン コーポレイション
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Publication of JP2002533124A publication Critical patent/JP2002533124A/ja
Publication of JP2002533124A5 publication Critical patent/JP2002533124A5/ja
Pending legal-status Critical Current

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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A61P31/18—Antivirals for RNA viruses for HIV
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JP2000591193A 1998-12-31 1999-12-30 Ｈｉｖポリペプチドの改善された発現およびウイルス様粒子の生成 Pending JP2002533124A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11449598P 1998-12-31 1998-12-31
US60/114,495 1998-12-31
US16847199P 1999-12-01 1999-12-01
US60/168,471 1999-12-01
PCT/US1999/031245 WO2000039302A2 (en) 1998-12-31 1999-12-30 Improved expression of hiv polypeptides and production of virus-like particles

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2010234059A Division JP2011019534A (ja) 1998-12-31 2010-10-18 Ｈｉｖポリペプチドの改善された発現およびウイルス様粒子の生成
JP2011123833A Division JP2011172593A (ja) 1998-12-31 2011-06-01 Ｈｉｖポリペプチドの改善された発現およびウイルス様粒子の生成

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JP2002533124A true JP2002533124A (ja) 2002-10-08
JP2002533124A5 JP2002533124A5 (enExample) 2007-02-22

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JP2000591193A Pending JP2002533124A (ja) 1998-12-31 1999-12-30 Ｈｉｖポリペプチドの改善された発現およびウイルス様粒子の生成
JP2010234059A Pending JP2011019534A (ja) 1998-12-31 2010-10-18 Ｈｉｖポリペプチドの改善された発現およびウイルス様粒子の生成
JP2011123833A Pending JP2011172593A (ja) 1998-12-31 2011-06-01 Ｈｉｖポリペプチドの改善された発現およびウイルス様粒子の生成

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JP2010234059A Pending JP2011019534A (ja) 1998-12-31 2010-10-18 Ｈｉｖポリペプチドの改善された発現およびウイルス様粒子の生成
JP2011123833A Pending JP2011172593A (ja) 1998-12-31 2011-06-01 Ｈｉｖポリペプチドの改善された発現およびウイルス様粒子の生成

Country Status (6)

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US (5) US6602705B1 (enExample)
EP (3) EP1141313A2 (enExample)
JP (3) JP2002533124A (enExample)
AU (1) AU2221600A (enExample)
CA (1) CA2360347C (enExample)
WO (1) WO2000039302A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004508808A (ja) * 2000-04-19 2004-03-25 オックスフォード　バイオメディカ（ユーケイ）リミテッド レトロウイルスパッケージング細胞での発現のためのコドン最適化
JP2012139221A (ja) * 2002-11-07 2012-07-26 Synergy America Inc 肺炎球菌感染を治療または予防するための組成物および方法
JP2015501657A (ja) * 2011-12-12 2015-01-19 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアＴｈｅ Ｃｈｉｌｄｒｅｎ’Ｓ Ｈｏｓｐｉｔａｌ Ｏｆ Ｐｈｉｌａｄｅｌｐｈｉａ 大規模な商業的レンチウィルスベクターの生産システム及びそれにより生産されるベクター
US9422342B2 (en) 2006-07-13 2016-08-23 Institute Of Advanced Study Recoding method that removes inhibitory sequences and improves HIV gene expression

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US20020173643A1 (en) * 1995-04-14 2002-11-21 Kappes John C. Fusion protein delivery system and uses thereof
EP2298900A1 (en) 1996-09-17 2011-03-23 Novartis Vaccines and Diagnostics, Inc. Compositions and methods for treating intracellular diseases
GB9803351D0 (en) 1998-02-17 1998-04-15 Oxford Biomedica Ltd Anti-viral vectors
US7622300B2 (en) 1998-06-03 2009-11-24 Kappes John C Trans-lentiviral vector particles and transduction of eukaryotic cells therewith
US6555342B1 (en) 1998-06-03 2003-04-29 Uab Research Foundation Fusion protein delivery system and uses thereof
AU2221600A (en) 1998-12-31 2000-07-31 Chiron Corporation Improved expression of hiv polypeptides and production of virus-like particles
EP1141314A2 (en) * 1998-12-31 2001-10-10 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
US7935805B1 (en) * 1998-12-31 2011-05-03 Novartis Vaccines & Diagnostics, Inc Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof
AU778106B2 (en) * 1999-04-26 2004-11-18 K.U. Leuven Research & Development Synthetic gene for expressing active retroviral protein in eukaryotes
ATE311205T1 (de) * 1999-06-11 2005-12-15 Medigene Inc Verwendung von viralen vektoren und geladenen molekülen für die gentherapie
US6710173B1 (en) * 1999-06-25 2004-03-23 Progenics Pharmaceuticals, Inc. Stabilized viral envelope proteins and uses thereof
CN1423698A (zh) * 1999-11-16 2003-06-11 真那特应用生物科技有限公司 Hiv－1亚型间(c/b’)基因组和其用途
JP4627950B2 (ja) * 1999-12-23 2011-02-09 アメリカ合衆国 変異ＨＩＶｇａｇ／ｐｏｌ、ＳＩＶｇａｇおよびＳＩＶｅｎｖ遺伝子を持つ分子クローン
US6656706B2 (en) 1999-12-23 2003-12-02 The United States Of America As Represented By The Department Of Health And Human Services Molecular clones with mutated HIV gag/pol, SIV gag and SIV env genes
KR100854917B1 (ko) 2000-03-30 2008-08-27 가부시키가이샤 디나벡크 겐큐쇼 센다이바이러스 벡터를 사용한 ａｉｄｓ 바이러스 백신
US7094882B2 (en) 2000-04-21 2006-08-22 Yeda Research And Development Co. Ltd. Growth factor which acts through erb b-4 rtk
US6783939B2 (en) 2000-07-07 2004-08-31 Alphavax, Inc. Alphavirus vectors and virosomes with modified HIV genes for use in vaccines
AU2001276752A1 (en) * 2000-08-08 2002-02-18 The Kitasato Institute Virus-like micrograins and process for producing the same
EP2302059A1 (en) 2000-08-14 2011-03-30 The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services Modifications of hiv Env, Gag, and Pol enhance immunogenicity for genetic immunization
US6582920B2 (en) * 2000-09-01 2003-06-24 Gen-Probe Incorporated Amplification of HIV-1 RT sequences for detection of sequences associated with drug-resistance mutations
JP2004508064A (ja) * 2000-09-15 2004-03-18 メルク　エンド　カムパニー　インコーポレーテッド コドン最適化ｈｉｖ１−ｇａｇ、ｐｏｌ、ｎｅｆおよび修飾体を発現する増強された第１世代アデノウイルスワクチン
US20030138453A1 (en) * 2000-09-28 2003-07-24 O'hagan Derek Microparticles for delivery of heterologous nucleic acids
AU2002225681A1 (en) * 2000-11-15 2002-05-27 Globe Immune, Inc. Yeast-dentritic cell vaccines and uses thereof
US20040161846A1 (en) * 2000-11-22 2004-08-19 Mason Anthony John Method of expression and agents identified thereby
AU2002305914A1 (en) 2001-01-12 2002-10-21 Chiron Corporation Nucleic acid mucosal immunization
CA2440433A1 (en) * 2001-03-09 2002-09-19 The Regents Of The University Of California Cell culture system for synthesis of infectious hepatitis c virus
US20060222656A1 (en) * 2005-04-01 2006-10-05 University Of Maryland, Baltimore MAGE-A3/HPV 16 peptide vaccines for head and neck cancer
US7842480B2 (en) * 2001-05-18 2010-11-30 Mayo Foundation For Medical Education And Research Chimeric antigen-specific t cell-activating polypeptides
ATE291925T1 (de) 2001-06-05 2005-04-15 Curevac Gmbh Stabilisierte mrna mit erhöhtem g/c-gehalt und optimierter codon usage für die gentherapie
EP1409694A4 (en) * 2001-07-05 2006-02-08 Chiron Corp POLYNUCLEOTIDES ENCODING ANTIGENIC POLYPEPTIDES OF HIV SUBTYPE B AND / OR SUBTYPE C, POLYPEPTIDES AND USES THEREOF
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JPN6009042215, Ｊ． Ｖｉｒｏｌ．， １９９８年， ｖｏｌ． ７２， ｎｏ． ２， ｐ． １４９７−１５０３ *
JPN6010034481, Ｇｅｎｅ, 1997, Ｖｏｌ．１９９, ｐｐ．２９３−３０１ *

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JP2004508808A (ja) * 2000-04-19 2004-03-25 オックスフォード　バイオメディカ（ユーケイ）リミテッド レトロウイルスパッケージング細胞での発現のためのコドン最適化
JP2012139221A (ja) * 2002-11-07 2012-07-26 Synergy America Inc 肺炎球菌感染を治療または予防するための組成物および方法
US9422342B2 (en) 2006-07-13 2016-08-23 Institute Of Advanced Study Recoding method that removes inhibitory sequences and improves HIV gene expression
US10815277B2 (en) 2006-07-13 2020-10-27 Institute For Advanced Study Viral inhibitory nucleotide sequences and vaccines
JP2015501657A (ja) * 2011-12-12 2015-01-19 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアＴｈｅ Ｃｈｉｌｄｒｅｎ’Ｓ Ｈｏｓｐｉｔａｌ Ｏｆ Ｐｈｉｌａｄｅｌｐｈｉａ 大規模な商業的レンチウィルスベクターの生産システム及びそれにより生産されるベクター

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EP2206785A1 (en) 2010-07-14
US20120269840A1 (en) 2012-10-25
JP2011172593A (ja) 2011-09-08
CA2360347A1 (en) 2000-07-06
WO2000039302A3 (en) 2001-01-04
US8168418B2 (en) 2012-05-01
EP1980617A1 (en) 2008-10-15
WO2000039302A2 (en) 2000-07-06
US6602705B1 (en) 2003-08-05
US7718401B2 (en) 2010-05-18
AU2221600A (en) 2000-07-31
CA2360347C (en) 2013-05-07
JP2011019534A (ja) 2011-02-03
US20030223964A1 (en) 2003-12-04

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