DE602006015050D1 - Tat-cd4-hiv-hybridmoleküle und verwendungsverfahren dafür - Google Patents
Tat-cd4-hiv-hybridmoleküle und verwendungsverfahren dafürInfo
- Publication number
- DE602006015050D1 DE602006015050D1 DE602006015050T DE602006015050T DE602006015050D1 DE 602006015050 D1 DE602006015050 D1 DE 602006015050D1 DE 602006015050 T DE602006015050 T DE 602006015050T DE 602006015050 T DE602006015050 T DE 602006015050T DE 602006015050 D1 DE602006015050 D1 DE 602006015050D1
- Authority
- DE
- Germany
- Prior art keywords
- hybrid molecules
- tat
- hiv
- polypeptides
- hiv hybrid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70514—CD4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65063505P | 2005-02-03 | 2005-02-03 | |
PCT/US2006/003935 WO2006084179A2 (en) | 2005-02-03 | 2006-02-03 | Hiv tat-cd4 hybried molecules and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006015050D1 true DE602006015050D1 (de) | 2010-08-05 |
Family
ID=36777987
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006015050T Active DE602006015050D1 (de) | 2005-02-03 | 2006-02-03 | Tat-cd4-hiv-hybridmoleküle und verwendungsverfahren dafür |
Country Status (8)
Country | Link |
---|---|
US (2) | US8168194B2 (de) |
EP (1) | EP1893650B1 (de) |
CN (1) | CN101146827A (de) |
AT (1) | ATE471947T1 (de) |
CA (1) | CA2597040A1 (de) |
DE (1) | DE602006015050D1 (de) |
WO (1) | WO2006084179A2 (de) |
ZA (1) | ZA200707138B (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG153796A1 (en) * | 2004-06-08 | 2009-07-29 | Novartis Vaccines & Diagnostic | Fusion proteins comprising cd4 minimal modules and methods of use thereof |
ATE471947T1 (de) | 2005-02-03 | 2010-07-15 | Novartis Vaccines & Diagnostic | Tat-cd4-hiv-hybridmoleküle und verwendungsverfahren dafür |
US8288345B2 (en) | 2007-03-02 | 2012-10-16 | Nono, Inc. | Treating stroke and other diseases without inhibiting N-type calcium channels |
EP2706356A1 (de) * | 2012-09-06 | 2014-03-12 | Laboratorios Del. Dr. Esteve, S.A. | Verfahren zur Identifizierung HIV-neutralisierender Antikörper |
CN111303243B (zh) * | 2020-02-25 | 2021-07-27 | 徐州医科大学 | 治疗缺血性脑损伤的小肽tat-akpd及其应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60500673A (ja) * | 1983-03-08 | 1985-05-09 | コモンウエルス セラム ラボラトリ−ズ コミツシヨン | 抗原活性を有するアミノ酸配列 |
US6004781A (en) * | 1988-01-22 | 1999-12-21 | The General Hospital Corporation | Nucleic acid encoding Ig-CD4 fusion proteins |
WO1993000103A1 (en) * | 1991-06-21 | 1993-01-07 | The Wistar Institute Of Anatomy And Biology | Chimeric envelope proteins for viral targeting |
US5817767A (en) | 1993-02-24 | 1998-10-06 | Progenics Pharmaceuticals, Inc. | Synergistic composition of CD4-based protein and anti-HIV-1 antibody, and methods of using same |
DK0699077T3 (da) * | 1993-05-07 | 2002-01-21 | Bio Merieux Inc | Immunogele HIV-komplekser |
WO1996004301A2 (en) | 1994-07-29 | 1996-02-15 | Chiron Corporation | Novel hepatitis c e1 and e2 truncated polypeptides and methods of obtaining the same |
CA2358915C (en) | 1998-12-31 | 2010-06-01 | Chiron Corporation | Modified hiv env polypeptides |
WO2000039302A2 (en) | 1998-12-31 | 2000-07-06 | Chiron Corporation | Improved expression of hiv polypeptides and production of virus-like particles |
US20020177551A1 (en) * | 2000-05-31 | 2002-11-28 | Terman David S. | Compositions and methods for treatment of neoplastic disease |
FR2799974B1 (fr) | 1999-10-25 | 2001-11-30 | Aventis Pasteur | Complexe deglycosyle proteine env/cd4 et son utilisation pour la vaccination contre le vih |
CA2458995C (en) | 2001-08-31 | 2013-04-30 | Chiron Corporation | Polynucleotides encoding antigenic hiv type b polypeptides, polypeptides and uses thereof |
BR0308896A (pt) * | 2002-05-07 | 2007-01-09 | Chiron Corp | complexos e hìbridos envelope do hiv-cd4 |
GB0218817D0 (en) | 2002-08-13 | 2002-09-18 | San Raffaele Centro Fond | Pharmaceutical compounds |
SG153796A1 (en) * | 2004-06-08 | 2009-07-29 | Novartis Vaccines & Diagnostic | Fusion proteins comprising cd4 minimal modules and methods of use thereof |
ATE471947T1 (de) | 2005-02-03 | 2010-07-15 | Novartis Vaccines & Diagnostic | Tat-cd4-hiv-hybridmoleküle und verwendungsverfahren dafür |
-
2006
- 2006-02-03 AT AT06734349T patent/ATE471947T1/de active
- 2006-02-03 EP EP06734349A patent/EP1893650B1/de not_active Not-in-force
- 2006-02-03 WO PCT/US2006/003935 patent/WO2006084179A2/en active Application Filing
- 2006-02-03 CA CA002597040A patent/CA2597040A1/en not_active Abandoned
- 2006-02-03 US US11/883,696 patent/US8168194B2/en not_active Expired - Fee Related
- 2006-02-03 DE DE602006015050T patent/DE602006015050D1/de active Active
- 2006-02-03 CN CNA2006800089748A patent/CN101146827A/zh active Pending
-
2007
- 2007-08-23 ZA ZA200707138A patent/ZA200707138B/xx unknown
-
2012
- 2012-03-22 US US13/427,234 patent/US8637044B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US8637044B2 (en) | 2014-01-28 |
EP1893650A2 (de) | 2008-03-05 |
US20080317779A1 (en) | 2008-12-25 |
CN101146827A (zh) | 2008-03-19 |
WO2006084179A2 (en) | 2006-08-10 |
CA2597040A1 (en) | 2006-08-10 |
US20120183557A1 (en) | 2012-07-19 |
US8168194B2 (en) | 2012-05-01 |
ZA200707138B (en) | 2008-11-26 |
EP1893650B1 (de) | 2010-06-23 |
WO2006084179A3 (en) | 2006-12-14 |
ATE471947T1 (de) | 2010-07-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1121327T1 (el) | Τροποποιημενα αντισωματα anti-il-23p19 | |
TW200738711A (en) | Chemical compounds | |
DK1866324T3 (da) | Phosphoramidatderivater af nukleosidforbindelser til anvendelse i behandlingen af cancer | |
MX2007001958A (es) | Compuestos quimicos. | |
DE602007010664D1 (de) | P53 aktivierende benzoylharnstoff- und benzoylthioharnstoff-verbindungen | |
WO2009044173A3 (en) | Methods of treating cancer using notch pathway inhibitors | |
NO20082531L (no) | Neuropilinantagonister | |
EA201590910A1 (ru) | Белки на основе структурного домена фибронектина, связывающие pcsk9 | |
DK1809661T3 (da) | Humant interferon-beta-mutein | |
NO20074943L (no) | Roflumilast for behandlingen av diabetes mellitus | |
EA200701825A1 (ru) | Вакцины против хламидиоза | |
EA201101520A1 (ru) | Способы диагностики онкологических заболеваний, использующие эпиметаболические переключатели, многоаспектные внутриклеточные молекулы или факторы влияния | |
NO20072733L (no) | Doseformer | |
EP1983002A3 (de) | Tyrosinphosphorylations-Stellen und spezifische Antikörper | |
WO2009090651A3 (en) | Major histocompatibility complex hla-b2705 ligands useful for therapy and diagnosis | |
DE602006015050D1 (de) | Tat-cd4-hiv-hybridmoleküle und verwendungsverfahren dafür | |
ATE479693T1 (de) | Phosphoindole als hiv-inhibitoren | |
WO2008125589A3 (de) | Tris(heterocyclyl)-metallkomplexe als bleichkatalysatoren | |
ATE459375T1 (de) | Copolymere auf basis von polyalkylenoxid- modifizierten n-vinyllactam-copolymeren | |
SG153796A1 (en) | Fusion proteins comprising cd4 minimal modules and methods of use thereof | |
MX2010010393A (es) | Uso de la catepsina c. | |
ATE483720T1 (de) | Verbindungen enthaltend organofluorochlorophosphatanionen | |
EP1975184A3 (de) | Serin- oder Threonin-Phosphorylationsorte | |
WO2009099601A3 (en) | Chk1 suppresses a caspase-2 apoptotic response to dna damage that bypasses p53, bcl-2 and caspase-3 | |
EP1988103A3 (de) | Tyrosinphosphorylationsstellen und spezifische Antikörper |