DE3689941D1 - Synthetische peptide und deren verwendung zur diagnose und impfung für aids und arc. - Google Patents

Synthetische peptide und deren verwendung zur diagnose und impfung für aids und arc.

Info

Publication number
DE3689941D1
DE3689941D1 DE3689941T DE3689941T DE3689941D1 DE 3689941 D1 DE3689941 D1 DE 3689941D1 DE 3689941 T DE3689941 T DE 3689941T DE 3689941 T DE3689941 T DE 3689941T DE 3689941 D1 DE3689941 D1 DE 3689941D1
Authority
DE
Germany
Prior art keywords
arc
aids
composition
vaccination
ligand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3689941T
Other languages
English (en)
Inventor
Ronald Kennedy
Gordon Dreesman
Myron Essex
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harvard College
Texas Biomedical Research Institute
Original Assignee
Harvard College
Texas Biomedical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College, Texas Biomedical Research Institute filed Critical Harvard College
Application granted granted Critical
Publication of DE3689941D1 publication Critical patent/DE3689941D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE3689941T 1985-10-24 1986-10-22 Synthetische peptide und deren verwendung zur diagnose und impfung für aids und arc. Expired - Lifetime DE3689941D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79083085A 1985-10-24 1985-10-24
PCT/US1986/002234 WO1987002775A1 (en) 1985-10-24 1986-10-22 Synthetic peptides and use for diagnosis and vaccination for aids and arc

Publications (1)

Publication Number Publication Date
DE3689941D1 true DE3689941D1 (de) 1994-08-04

Family

ID=25151854

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3689941T Expired - Lifetime DE3689941D1 (de) 1985-10-24 1986-10-22 Synthetische peptide und deren verwendung zur diagnose und impfung für aids und arc.

Country Status (6)

Country Link
EP (1) EP0245362B1 (de)
JP (1) JPS63501716A (de)
AT (1) ATE108022T1 (de)
CA (1) CA1305828C (de)
DE (1) DE3689941D1 (de)
WO (1) WO1987002775A1 (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2625100A2 (fr) * 1986-03-13 1989-06-30 Lurhuma Zirimwabagabo Utilisation d'antigenes pour la preparation de vaccins, proteine rendue immunogene et composition pharmaceutique la comportant
US4925784A (en) * 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
ATE96450T1 (de) * 1986-06-03 1993-11-15 Us Commerce Kleine peptide, die die bindung an t-4-rezeptoren inhibieren und als immunogene wirken.
NZ221440A (en) * 1986-08-20 1991-11-26 Genetic Systems Corp Composition containing monoclonal antibodies/peptides useful in treating and diagnosing hiv infections
US5976541A (en) * 1988-01-26 1999-11-02 The United States Of America As Represented By The Department Of Health And Human Services Potent peptide for stimulation of cytotoxic T lymphocytes specific for the HIV-1 envelope
US5030449A (en) * 1988-07-21 1991-07-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Synthetic vaccine against AIDS virus
US5981278A (en) * 1987-05-29 1999-11-09 Tanox, Inc. Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS
US5834599A (en) * 1987-05-29 1998-11-10 Tanox Biosystems, Inc. Immunoconjugates which neutralize HIV-1 infection
JP2520464B2 (ja) * 1987-05-29 1996-07-31 タノツクス・バイオシステムズ・インコーポレーテツド Ｈｉｖ―１を中和するモノクロ―ナル抗体
US6657050B1 (en) 1987-05-29 2003-12-02 Tanox, Inc. Chimeric viral-neutralizing immunoglobulins
US5019387A (en) * 1987-09-08 1991-05-28 Duke University Production of antibodies to HIV
US5013548A (en) * 1987-09-08 1991-05-07 Duke University Production of antibodies to HIV
NL8702403A (nl) * 1987-10-09 1989-05-01 Stichting Centr Diergeneeskund Oligopeptiden en gebruik daarvan voor diagnostische en vaccinatiedoeleinden voor aids en arc.
ATE85215T1 (de) * 1987-12-19 1993-02-15 Experimentelle Chirurgie Lab Antivirales therapeutikum.
WO1989005821A1 (en) * 1987-12-21 1989-06-29 Arch Development Corporation Hiv-related antigens and antibodies
WO1989005820A1 (en) * 1987-12-21 1989-06-29 Arch Development Corporation Hiv-related antigens and antibodies
US5820865A (en) * 1988-01-26 1998-10-13 The United States Of America As Represented By The Department Of Health And Human Services Method to induce cytotoxic T Lymphocytes specific for a broad array of HIV-1 isolates using hybrid synthetic peptides
WO1989007112A1 (en) * 1988-01-26 1989-08-10 The United States Of America, As Represented By Th A synthetic antigen evoking anti-hiv response
US5763160A (en) * 1988-02-12 1998-06-09 United Biomedical, Inc. Synthetic peptides and process of using same for the detection of antibodies to human immunodeficiency virus (HIV) gp120 envelope protein, diagnosis of AIDS and pre-AIDS conditions and as vaccines
WO1989009785A1 (en) * 1988-04-07 1989-10-19 The Trustees Of The University Of Alabama Peptides inhibitors of hiv induced cell fusions and syncytia formation
EP0339504A3 (de) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Menschliches immunoinsuffizientes Virus (HIV) env-codiertes Peptid, welches im Stande ist, die HIV hemmenden Antikörper bei Säugetieren hervorzurufen
US5562905A (en) * 1988-04-26 1996-10-08 E. I. Du Pont De Nemours And Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
IT1226552B (it) * 1988-07-29 1991-01-24 Ellem Ind Farmaceutica Peptidi immunostimolanti.
EP0362909A3 (de) * 1988-08-26 1990-11-14 Akzo N.V. Synthetische Polypeptide, immunochemisch aktiv mit HIV-Antikörpern
AU640619B2 (en) * 1988-10-03 1993-09-02 Repligen Corporation Hiv proteins and peptides useful in the diagnosis, prophylaxis or therapy of aids
AU641375B2 (en) * 1988-12-20 1993-09-23 Clarity Technologies Incorporated Synthetic HIV-like peptides, their compositions and uses
GB8910145D0 (en) * 1989-05-03 1989-06-21 Connaught Lab Synthetic peptides for an hiv-1 vaccine
US6248574B1 (en) * 1989-12-13 2001-06-19 Avigdor Shaffermann Polypeptides selectively reactive with antibodies against human immunodeficiency virus and vaccines comprising the polypeptides
US5914109A (en) * 1990-06-15 1999-06-22 New York University Heterohybridomas producing human monoclonal antibodies to HIV-1
KR100220531B1 (ko) * 1990-08-22 1999-10-01 앤더스 발네 인간의 면역 결핍 바이러스 감염을 차단시키는 펩티드 및 그것의 사용 방법
US5627035A (en) * 1990-08-22 1997-05-06 Syntello Vaccine Development Ab Peptides that block human immunodeficiency virus and methods of use thereof
JP2003523721A (ja) 1998-12-31 2003-08-12 カイロン コーポレイション 抗原性ｈｉｖｃ型ポリペプチドをコードするポリヌクレオチド、ポリペプチド、およびそれらの使用
US7935805B1 (en) 1998-12-31 2011-05-03 Novartis Vaccines & Diagnostics, Inc Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof
CA2360347C (en) 1998-12-31 2013-05-07 Chiron Corporation Improved expression of hiv polypeptides and production of virus-like particles
ES2299276T3 (es) 1998-12-31 2008-05-16 Novartis Vaccines And Diagnostics, Inc. Polipeptidos env del vih modificados.
EP1035219A1 (de) * 1999-02-25 2000-09-13 Universiteit Gent Gastrische Helicobacter 16S-rDNA Sequenzen von Rind und Schwein und ihre Anwendung zur Detektion and Typisierung von Helicobacter Stämmen
US7211659B2 (en) 2001-07-05 2007-05-01 Chiron Corporation Polynucleotides encoding antigenic HIV type C polypeptides, polypeptides and uses thereof
US20030170614A1 (en) 2001-08-31 2003-09-11 Megede Jan Zur Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof
EP1427806A4 (de) 2001-08-31 2006-04-26 Chiron Corp Antigene hiv-typ-b-polypeptide codierende polynukleotide, polypeptide und verwendungen davon
BRPI0611927A2 (pt) * 2005-06-23 2011-08-16 Rapid Pharmaceuticals Ag composições terapêuticas

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117113A (en) * 1974-06-25 1978-09-26 National Research Development Corporation Immunological preparations
IL61904A (en) * 1981-01-13 1985-07-31 Yeda Res & Dev Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same
FR2571968B1 (fr) * 1984-10-18 1989-03-17 Pasteur Institut Virus purifie des lymphadenopathies et du syndrome d'immuno-depression acquise et antigenes d'enveloppe de ce virus, procede d'obtention de ce virus et de ces antigenes d'enveloppe de ce virus, applications de ce virus ou de ces antigenes a la preparation de compositions immunogenes ou pour le diagnostic des susdites affections.
EP0201540B2 (de) * 1984-10-18 2001-10-31 Institut Pasteur Lymphadenopathie-assoziierte hüllenantigene und deren verwendungen
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences
AU600658B2 (en) * 1984-12-24 1990-08-23 Genentech Inc. Molecularly cloned acquired immunodeficiency syndrome polypeptides and their methods of use
JP2702911B2 (ja) * 1985-09-11 1998-01-26 ユナイテツド・バイオメデイカル・インコ−ポレ−テツド 合成ペプチド、並びにそれを用いたエイズおよびプリ・エイズの検出方法
ES2054616T3 (es) * 1985-12-17 1994-08-16 Akzo Nv Reactivo inmunoquimico.

Also Published As

Publication number Publication date
EP0245362A1 (de) 1987-11-19
JPS63501716A (ja) 1988-07-14
WO1987002775A1 (en) 1987-05-07
ATE108022T1 (de) 1994-07-15
EP0245362A4 (de) 1990-04-10
CA1305828C (en) 1992-07-28
EP0245362B1 (de) 1994-06-29

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Legal Events

Date Code Title Description
8380 Miscellaneous part iii

Free format text: DIE INHABER SIND ZU AENDERN IN: KENNEDY, RONALD, C., SAN ANTONIO, TEX., US KANDA, PATRICK, SAN ANTONIO, TEX., US

8332 No legal effect for de