JP2002523375A5 - - Google Patents

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Publication number
JP2002523375A5
JP2002523375A5 JP2000565916A JP2000565916A JP2002523375A5 JP 2002523375 A5 JP2002523375 A5 JP 2002523375A5 JP 2000565916 A JP2000565916 A JP 2000565916A JP 2000565916 A JP2000565916 A JP 2000565916A JP 2002523375 A5 JP2002523375 A5 JP 2002523375A5
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JP
Japan
Prior art keywords
use according
human
risk
daily dose
human patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000565916A
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English (en)
Japanese (ja)
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JP2002523375A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US1999/018961 external-priority patent/WO2000010596A1/en
Publication of JP2002523375A publication Critical patent/JP2002523375A/ja
Publication of JP2002523375A5 publication Critical patent/JP2002523375A5/ja
Pending legal-status Critical Current

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JP2000565916A 1998-08-19 1999-08-19 骨の靭性、及び、剛性を増し、骨折を減少させる方法 Pending JP2002523375A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US9715198P 1998-08-19 1998-08-19
US60/097,151 1998-08-19
US9974698P 1998-09-10 1998-09-10
US60/099,746 1998-09-10
PCT/US1999/018961 WO2000010596A1 (en) 1998-08-19 1999-08-19 Method of increasing bone toughness and stiffness and reducing fractures

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010244314A Division JP2011021035A (ja) 1998-08-19 2010-10-29 骨の靭性、及び、剛性を増し、骨折を減少させる方法

Publications (2)

Publication Number Publication Date
JP2002523375A JP2002523375A (ja) 2002-07-30
JP2002523375A5 true JP2002523375A5 (https=) 2009-01-29

Family

ID=26792729

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2000565916A Pending JP2002523375A (ja) 1998-08-19 1999-08-19 骨の靭性、及び、剛性を増し、骨折を減少させる方法
JP2010244314A Withdrawn JP2011021035A (ja) 1998-08-19 2010-10-29 骨の靭性、及び、剛性を増し、骨折を減少させる方法
JP2014061763A Expired - Lifetime JP6177718B2 (ja) 1998-08-19 2014-03-25 骨の靭性、及び、剛性を増し、骨折を減少させる方法
JP2014204577A Withdrawn JP2015028065A (ja) 1998-08-19 2014-10-03 骨の靭性、及び、剛性を増し、骨折を減少させる方法
JP2017124301A Withdrawn JP2017190332A (ja) 1998-08-19 2017-06-26 骨の靭性、及び、剛性を増し、骨折を減少させる方法

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2010244314A Withdrawn JP2011021035A (ja) 1998-08-19 2010-10-29 骨の靭性、及び、剛性を増し、骨折を減少させる方法
JP2014061763A Expired - Lifetime JP6177718B2 (ja) 1998-08-19 2014-03-25 骨の靭性、及び、剛性を増し、骨折を減少させる方法
JP2014204577A Withdrawn JP2015028065A (ja) 1998-08-19 2014-10-03 骨の靭性、及び、剛性を増し、骨折を減少させる方法
JP2017124301A Withdrawn JP2017190332A (ja) 1998-08-19 2017-06-26 骨の靭性、及び、剛性を増し、骨折を減少させる方法

Country Status (32)

Country Link
US (2) US6977077B1 (https=)
EP (3) EP2266598B1 (https=)
JP (5) JP2002523375A (https=)
KR (1) KR100454207B1 (https=)
CN (1) CN1205997C (https=)
AR (1) AR033639A1 (https=)
AT (1) ATE231000T1 (https=)
AU (1) AU746277B2 (https=)
BR (1) BR9909445A (https=)
CA (1) CA2325371C (https=)
CO (1) CO5130020A1 (https=)
CY (2) CY1113343T1 (https=)
CZ (1) CZ301017B6 (https=)
DE (2) DE15152726T1 (https=)
DK (4) DK2266598T3 (https=)
DZ (1) DZ2873A1 (https=)
EA (1) EA003362B1 (https=)
ES (4) ES2393200T3 (https=)
HR (1) HRP20000755A2 (https=)
HU (2) HU1200430D0 (https=)
ID (1) ID29039A (https=)
IL (2) IL138829A0 (https=)
MY (1) MY129227A (https=)
NO (2) NO323984B1 (https=)
NZ (1) NZ507056A (https=)
PE (1) PE20001089A1 (https=)
PL (1) PL201688B1 (https=)
PT (4) PT1769804E (https=)
TR (1) TR200003455T2 (https=)
TW (1) TW576747B (https=)
UA (1) UA72205C2 (https=)
WO (1) WO2000010596A1 (https=)

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US6770623B1 (en) * 1997-12-09 2004-08-03 Eli Lilly And Company Stabilized teriparatide solutions
US20040033950A1 (en) * 2000-09-26 2004-02-19 Hock Janet M. Method of increasing bone toughness and stiffness and reducing fractures
DZ2873A1 (fr) 1998-08-19 2003-12-15 Lilly Co Eli Procédé pour augmenter la dureté et la rigidité osseuse.
CA2387693A1 (en) * 1999-09-20 2001-03-29 Eli Lilly And Company Method for monitoring treatment with a parathyroid hormone
US7247609B2 (en) 2001-12-18 2007-07-24 Universitat Zurich Growth factor modified protein matrices for tissue engineering
AU2003207512B2 (en) 2002-01-10 2008-06-12 Osteotrophin Llc Treatment of bone disorders with skeletal anabolic drugs
US8088734B2 (en) 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
KR20060058133A (ko) * 2003-09-19 2006-05-29 화이자 프로덕츠 인코포레이티드 2-알킬리덴-19-노르-비타민 d 유도체 및 부갑상선호르몬의 조합을 포함하는 약학 조성물 및 방법
MXPA06012980A (es) * 2004-05-10 2007-06-12 Nastech Pharm Co Composiciones y metodos para el suministro mucosal mejorado de la hormona paratiroidea.
US20060052305A1 (en) * 2004-05-10 2006-03-09 Nastech Pharmaceutical Company Inc. Method of treating osteoporosis using intranasal parathyroid hormone
US20060127320A1 (en) * 2004-05-10 2006-06-15 Nastech Pharmaceutical Company Inc. Method of delivering parathyroid hormone to a human
US20060189533A1 (en) * 2004-05-10 2006-08-24 Nastech Pharmaceutical Company Inc. Stable pharmaceutical dosage forms of teriparatide
MXPA06013168A (es) 2004-05-13 2007-05-15 Johnson & Johnson Aparato y metodo para el suministro transdermico de agentes de la hormona paratiroidea.
US7648965B2 (en) 2004-05-14 2010-01-19 Unigene Laboratories Inc. Method for fostering bone formation and preservation
US20060069021A1 (en) * 2004-08-13 2006-03-30 Nastech Pharmaceutical Company Inc. Compositions and methods for intranasal administration of inactive analogs of PTH or inactivated preparations of PTH or PTH analogs
WO2006073711A2 (en) 2005-01-06 2006-07-13 Kuros Biosurgery Ag Use of a matrix comprising a contrast agent in soft tissues
US8575101B2 (en) 2005-01-06 2013-11-05 Kuros Biosurgery Ag Supplemented matrices for the repair of bone fractures
JP2008540522A (ja) * 2005-05-11 2008-11-20 ユニジーン・ラボラトリーズ・インコーポレーテッド 骨の形成および保存を促進するための方法
US20070173447A1 (en) * 2005-10-25 2007-07-26 Nastech Pharmaceutical Company Inc. Method for treating osteoporosis by intranasal delivery of teriparatide with an anti-resorptive agent
CN101355959B (zh) * 2005-11-10 2013-02-27 密歇根理工大学管理委员会 黑熊甲状旁腺素和使用黑熊甲状旁腺素的方法
US20080051332A1 (en) * 2005-11-18 2008-02-28 Nastech Pharmaceutical Company Inc. Method of modulating hematopoietic stem cells and treating hematologic diseases using intranasal parathyroid hormone
US20080119408A1 (en) * 2006-07-07 2008-05-22 Nastech Pharmaceutical Company Inc. Pth formulations for intranasal delivery
EP1961765A1 (en) * 2006-12-08 2008-08-27 Zealand Pharma A/S Truncated PTH peptides with a cyclic conformation
PL2136850T3 (pl) 2007-04-13 2012-07-31 Kuros Biosurgery Ag Polimeryczny uszczelniacz tkankowy
US20110137243A1 (en) * 2007-09-06 2011-06-09 Abbott Cardiovascular Systems Inc. Coating On A Balloon Device
US9457056B2 (en) * 2007-12-04 2016-10-04 Ben-Gurion University Of The Negev Research And Development Authority Peptides comprising alternating hydrophobic and anionic amino acids for treatment of osteoporosis
CA2710798A1 (en) 2007-12-28 2009-07-09 Kuros Biosurgery Ag Pdgf fusion proteins incorporated into fibrin foams
ES2662018T3 (es) * 2009-09-09 2018-04-05 Asahi Kasei Pharma Corporation Agente terapéutico/profiláctico que contiene PTH para la osteoporosis, caracterizado porque la PTH se administra una vez por semana en una dosis unitaria de 200 unidades
EP2509996A1 (en) 2009-12-07 2012-10-17 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US9295663B2 (en) 2010-07-14 2016-03-29 Abbott Cardiovascular Systems Inc. Drug coated balloon with in-situ formed drug containing microspheres
WO2012111852A1 (ja) * 2011-02-17 2012-08-23 帝人ファーマ株式会社 椎体骨折治療剤及びその評価方法
EP2686027B1 (en) 2011-03-16 2021-05-05 Kuros Biosurgery AG Pharmaceutical formulation for use in spinal fusion
WO2012169435A1 (ja) 2011-06-07 2012-12-13 旭化成ファーマ株式会社 高純度pth含有凍結乾燥製剤およびその製造方法
US9700485B2 (en) 2013-04-24 2017-07-11 Corning Incorporated Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
CA3013443C (en) 2016-02-01 2021-06-15 Eli Lilly And Company Parathyroid hormone - anti-rankl antibody fusion compounds
US20190381341A1 (en) * 2017-02-01 2019-12-19 The Johns Hopkins University Parathyroid hormone and regeneration of degenerative discs disease
JP6577683B2 (ja) * 2017-09-22 2019-09-18 旭化成ファーマ株式会社 安定性に優れるテリパラチド含有液状医薬組成物
JP6618139B1 (ja) 2018-10-29 2019-12-11 旭化成ファーマ株式会社 週2回の頻度でテリパラチド又はその塩を投与することを特徴とする、骨粗鬆症の予防又は治療方法
US12344649B2 (en) 2019-08-09 2025-07-01 Flagship Pioneering Innovations Vi, Llc Modulators of parathyroid hormone receptor (PTHR1)
GB2590692A (en) * 2019-12-24 2021-07-07 Corthotec Ltd Composition for improved bone fracture healing

Family Cites Families (18)

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US4086196A (en) 1975-03-28 1978-04-25 Armour Pharmaceutical Company Parathyroid hormone
IL78342A (en) 1985-04-04 1991-06-10 Gen Hospital Corp Pharmaceutical composition for treatment of osteoporosis in humans comprising a parathyroid hormone or a fragment thereof
DE3935738A1 (de) 1989-10-27 1991-05-08 Forssmann Wolf Georg Arzneimittel, enthaltend das humane parathormon-fragment (1-37) als aktiven wirkstoff
US5208041A (en) 1991-05-23 1993-05-04 Allelix Biopharmaceuticals Inc. Essentially pure human parathyroid hormone
CA2126299C (en) 1994-06-20 2000-12-12 Gordon E. Willick Parathyroid hormone analogues for the treatment of osteoporosis
JPH0873376A (ja) 1994-09-07 1996-03-19 Asahi Chem Ind Co Ltd 骨粗鬆症治療薬
US5747456A (en) * 1994-12-19 1998-05-05 Beth Israel Deaconess Medical Center Continuous low-dose administration of parathyroid hormone or its agonist
WO1996019246A1 (en) * 1994-12-19 1996-06-27 Beth Israel Hospital Association Continuous low-dose administration of parathyroid hormone or its agonist
CA2206657C (en) * 1994-12-22 2009-05-19 Astra Aktiebolag Therapeutic preparation for inhalation containing parathyroid hormone, pth
JPH08310965A (ja) 1995-05-16 1996-11-26 Chugai Pharmaceut Co Ltd 骨癒合促進剤
RS49707B (sr) * 1997-09-09 2007-12-31 F.Hoffmann-La Roche Ag., Primena polipeptidnog analoga peptida srodnog paratireoidnom hormonu i njegovih soli za proizvodnju medikamenata za lečenje preloma kostiju
ZA9811127B (en) 1997-12-09 2000-07-11 Lilly Co Eli Stabilized teriparatide solutions.
DZ2873A1 (fr) * 1998-08-19 2003-12-15 Lilly Co Eli Procédé pour augmenter la dureté et la rigidité osseuse.
US20040033950A1 (en) 2000-09-26 2004-02-19 Hock Janet M. Method of increasing bone toughness and stiffness and reducing fractures
US6907597B1 (en) 2000-10-13 2005-06-14 Ati International Srl Method and apparatus for constructing an executable program in memory
US6967759B2 (en) 2001-12-31 2005-11-22 Texas Instruments Incorporated Pulse width modulation sequence generation
JP5796714B2 (ja) 2012-01-13 2015-10-21 株式会社リコー 定着装置及び画像形成装置
EP2949301B1 (en) 2014-05-27 2018-04-18 The Procter and Gamble Company Absorbent core with curved and straight absorbent material areas

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