DK1769804T3 - hPTH(1-34) til anvendelse ved forebyggelse eller reduktion af forekomsten eller voldsomheden af vertebral og/eller ikke-vertebral fraktur hos en mand - Google Patents

hPTH(1-34) til anvendelse ved forebyggelse eller reduktion af forekomsten eller voldsomheden af vertebral og/eller ikke-vertebral fraktur hos en mand

Info

Publication number
DK1769804T3
DK1769804T3 DK06027055.0T DK06027055T DK1769804T3 DK 1769804 T3 DK1769804 T3 DK 1769804T3 DK 06027055 T DK06027055 T DK 06027055T DK 1769804 T3 DK1769804 T3 DK 1769804T3
Authority
DK
Denmark
Prior art keywords
vertebral
hpth
severity
incidence
man
Prior art date
Application number
DK06027055.0T
Other languages
English (en)
Inventor
Gregory A Gaich
Willard H Dere
Janet M Hock
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26792729&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1769804(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Priority claimed from EP02079227A external-priority patent/EP1295605A3/en
Application granted granted Critical
Publication of DK1769804T3 publication Critical patent/DK1769804T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/29—Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Steroid Compounds (AREA)
  • Materials For Medical Uses (AREA)
DK06027055.0T 1998-08-19 1999-08-19 hPTH(1-34) til anvendelse ved forebyggelse eller reduktion af forekomsten eller voldsomheden af vertebral og/eller ikke-vertebral fraktur hos en mand DK1769804T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9715198P 1998-08-19 1998-08-19
US9974698P 1998-09-10 1998-09-10
EP02079227A EP1295605A3 (en) 1998-08-19 1999-08-19 Method of increasing bone toughness and stiffness and reducing fractures

Publications (1)

Publication Number Publication Date
DK1769804T3 true DK1769804T3 (da) 2012-10-15

Family

ID=26792729

Family Applications (4)

Application Number Title Priority Date Filing Date
DK06027055.0T DK1769804T3 (da) 1998-08-19 1999-08-19 hPTH(1-34) til anvendelse ved forebyggelse eller reduktion af forekomsten eller voldsomheden af vertebral og/eller ikke-vertebral fraktur hos en mand
DK99942350T DK1059933T3 (da) 1998-08-19 1999-08-19 Anvendelse af parathyroideahormon bestående af aminosyresekvens 1-34 af humant parathyroideahormon til reduktion af risikoen for både hvirvel- og ikke-hvirvel knoglefraktur
DK10180447.4T DK2266598T3 (da) 1998-08-19 1999-08-19 Fremgangsmåde til at øge knoglehårdhed og -stivhed og at reducere brud
DK15152726.4T DK2907522T3 (da) 1998-08-19 1999-08-19 Fremgangsmåde til øgning af knoglehårdhed og stivhed og reduktion af frakturer

Family Applications After (3)

Application Number Title Priority Date Filing Date
DK99942350T DK1059933T3 (da) 1998-08-19 1999-08-19 Anvendelse af parathyroideahormon bestående af aminosyresekvens 1-34 af humant parathyroideahormon til reduktion af risikoen for både hvirvel- og ikke-hvirvel knoglefraktur
DK10180447.4T DK2266598T3 (da) 1998-08-19 1999-08-19 Fremgangsmåde til at øge knoglehårdhed og -stivhed og at reducere brud
DK15152726.4T DK2907522T3 (da) 1998-08-19 1999-08-19 Fremgangsmåde til øgning af knoglehårdhed og stivhed og reduktion af frakturer

Country Status (33)

Country Link
US (2) US6977077B1 (da)
EP (3) EP1059933B1 (da)
JP (5) JP2002523375A (da)
KR (1) KR100454207B1 (da)
CN (1) CN1205997C (da)
AR (1) AR033639A1 (da)
AT (1) ATE231000T1 (da)
AU (1) AU746277B2 (da)
BR (1) BR9909445A (da)
CA (1) CA2325371C (da)
CO (1) CO5130020A1 (da)
CY (2) CY1113343T1 (da)
CZ (1) CZ301017B6 (da)
DE (2) DE69904918T2 (da)
DK (4) DK1769804T3 (da)
DZ (1) DZ2873A1 (da)
EA (1) EA003362B1 (da)
ES (4) ES2549551T3 (da)
HK (3) HK1030545A1 (da)
HR (1) HRP20000755A2 (da)
HU (2) HU230697B1 (da)
ID (1) ID29039A (da)
IL (2) IL138829A0 (da)
MY (1) MY129227A (da)
NO (2) NO323984B1 (da)
NZ (1) NZ507056A (da)
PE (1) PE20001089A1 (da)
PL (1) PL201688B1 (da)
PT (4) PT1059933E (da)
TR (1) TR200003455T2 (da)
TW (1) TW576747B (da)
UA (1) UA72205C2 (da)
WO (1) WO2000010596A1 (da)

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DZ2873A1 (fr) 1998-08-19 2003-12-15 Lilly Co Eli Procédé pour augmenter la dureté et la rigidité osseuse.
US20040033950A1 (en) * 2000-09-26 2004-02-19 Hock Janet M. Method of increasing bone toughness and stiffness and reducing fractures
CA2387693A1 (en) * 1999-09-20 2001-03-29 Eli Lilly And Company Method for monitoring treatment with a parathyroid hormone
US7247609B2 (en) 2001-12-18 2007-07-24 Universitat Zurich Growth factor modified protein matrices for tissue engineering
MXPA04006728A (es) * 2002-01-10 2005-08-19 Osteotrophin Llc Tratamiento de desordenes oseos con medicamentos anabolicos esqueleticos.
US8088734B2 (en) 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
CN1852716A (zh) * 2003-09-19 2006-10-25 辉瑞产品公司 包括2－亚烷基－19－去甲基－维生素d衍生物和甲状旁腺激素的组合的药物组合物和方法
RU2006143544A (ru) * 2004-05-10 2008-06-20 Нэстек Фармасьютикал Кампани Инк. (Us) Композиции и способ для облегченной чресслизистой доставки паратиреоидного гормона
US20060189533A1 (en) * 2004-05-10 2006-08-24 Nastech Pharmaceutical Company Inc. Stable pharmaceutical dosage forms of teriparatide
US20060052305A1 (en) * 2004-05-10 2006-03-09 Nastech Pharmaceutical Company Inc. Method of treating osteoporosis using intranasal parathyroid hormone
US20060127320A1 (en) * 2004-05-10 2006-06-15 Nastech Pharmaceutical Company Inc. Method of delivering parathyroid hormone to a human
EP1744683B1 (en) 2004-05-13 2016-03-16 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
US7648965B2 (en) 2004-05-14 2010-01-19 Unigene Laboratories Inc. Method for fostering bone formation and preservation
US20060069021A1 (en) * 2004-08-13 2006-03-30 Nastech Pharmaceutical Company Inc. Compositions and methods for intranasal administration of inactive analogs of PTH or inactivated preparations of PTH or PTH analogs
WO2006073711A2 (en) 2005-01-06 2006-07-13 Kuros Biosurgery Ag Use of a matrix comprising a contrast agent in soft tissues
US8575101B2 (en) 2005-01-06 2013-11-05 Kuros Biosurgery Ag Supplemented matrices for the repair of bone fractures
EP1879608A4 (en) * 2005-05-11 2009-11-11 Unigene Lab Inc METHOD FOR STIMULATING BONE FORMATION AND PRESERVATION
US20070173447A1 (en) * 2005-10-25 2007-07-26 Nastech Pharmaceutical Company Inc. Method for treating osteoporosis by intranasal delivery of teriparatide with an anti-resorptive agent
CA2628945A1 (en) * 2005-11-10 2007-05-24 Board Of Control Of Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US20080051332A1 (en) * 2005-11-18 2008-02-28 Nastech Pharmaceutical Company Inc. Method of modulating hematopoietic stem cells and treating hematologic diseases using intranasal parathyroid hormone
US20080119408A1 (en) * 2006-07-07 2008-05-22 Nastech Pharmaceutical Company Inc. Pth formulations for intranasal delivery
EP1961765A1 (en) * 2006-12-08 2008-08-27 Zealand Pharma A/S Truncated PTH peptides with a cyclic conformation
CN101711168B (zh) 2007-04-13 2013-05-01 库罗斯生物外科股份公司 聚合物组织封闭剂
US20110137243A1 (en) * 2007-09-06 2011-06-09 Abbott Cardiovascular Systems Inc. Coating On A Balloon Device
EP2217260B1 (en) * 2007-12-04 2016-11-09 Ben-Gurion University Of The Negev Research And Development Authority Amphiphilic peptide matrices for treatment of osteoporosis
WO2009083544A2 (en) 2007-12-28 2009-07-09 Kuros Biosurgery Ag Pdgf fusion proteins incorporated into fibrin foams
KR20120067336A (ko) 2009-09-09 2012-06-25 아사히 가세이 파마 가부시키가이샤 1회당 100～200 단위의 ｐｔｈ가 주 1회 투여되는 것을 특징으로 하는, ｐｔｈ 함유 골다공증 치료/예방제
WO2011071480A1 (en) 2009-12-07 2011-06-16 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US9295663B2 (en) 2010-07-14 2016-03-29 Abbott Cardiovascular Systems Inc. Drug coated balloon with in-situ formed drug containing microspheres
WO2012111852A1 (ja) * 2011-02-17 2012-08-23 帝人ファーマ株式会社 椎体骨折治療剤及びその評価方法
ES2882852T3 (es) 2011-03-16 2021-12-02 Kuros Biosurgery Ag Formulación farmacéutica para la utilización en la fusión espinal
JPWO2012169435A1 (ja) 2011-06-07 2015-02-23 旭化成ファーマ株式会社 高純度ｐｔｈ含有凍結乾燥製剤およびその製造方法
US9700485B2 (en) 2013-04-24 2017-07-11 Corning Incorporated Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
EP3411066A1 (en) 2016-02-01 2018-12-12 Eli Lilly and Company Parathyroid hormone anti-rankl antibody fusion compounds
WO2018144719A1 (en) * 2017-02-01 2018-08-09 The Johns Hopkins University Parathyroid hormone and regeneration of degenerative discs disease
CN110996988A (zh) * 2017-09-22 2020-04-10 旭化成制药株式会社 稳定性优异的含有特立帕肽的液态药物组合物
WO2020090174A1 (ja) 2018-10-29 2020-05-07 旭化成ファーマ株式会社 週２回の頻度でテリパラチド又はその塩を投与することを特徴とする、骨粗鬆症の予防又は治療方法
JP2022543871A (ja) 2019-08-09 2022-10-14 フラッグシップ・パイオニアリング・イノベーションズ・ブイアイ，エルエルシー 副甲状腺ホルモン受容体（ｐｔｈｒ１）の調節剤
GB2590692A (en) * 2019-12-24 2021-07-07 Corthotec Ltd Composition for improved bone fracture healing

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MY120063A (en) 1997-12-09 2005-08-30 Lilly Co Eli Stabilized teriparatide solutions
DZ2873A1 (fr) 1998-08-19 2003-12-15 Lilly Co Eli Procédé pour augmenter la dureté et la rigidité osseuse.
US20040033950A1 (en) 2000-09-26 2004-02-19 Hock Janet M. Method of increasing bone toughness and stiffness and reducing fractures
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US6967759B2 (en) 2001-12-31 2005-11-22 Texas Instruments Incorporated Pulse width modulation sequence generation
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Also Published As

Publication number Publication date
HK1212602A1 (zh) 2016-06-17
JP6177718B2 (ja) 2017-08-09
CO5130020A1 (es) 2002-02-27
HK1030545A1 (en) 2001-05-11
AR033639A1 (es) 2004-01-07
NO20005947D0 (no) 2000-11-24
NZ507056A (en) 2003-10-31
CN1308545A (zh) 2001-08-15
ES2393200T3 (es) 2012-12-19
JP2015028065A (ja) 2015-02-12
CY1113343T1 (el) 2016-06-22
US6977077B1 (en) 2005-12-20
IL138829A (en) 2011-01-31
UA72205C2 (uk) 2005-02-15
EP2907522A1 (en) 2015-08-19
US7163684B2 (en) 2007-01-16
PL201688B1 (pl) 2009-04-30
HUP0101594A2 (hu) 2001-11-28
AU746277B2 (en) 2002-04-18
JP2017190332A (ja) 2017-10-19
JP2014139220A (ja) 2014-07-31
EP2266598B1 (en) 2017-02-22
DE15152726T1 (de) 2015-12-10
EP1059933A1 (en) 2000-12-20
KR100454207B1 (ko) 2004-10-26
EA200001015A1 (ru) 2001-02-26
JP2011021035A (ja) 2011-02-03
HK1102496A1 (en) 2007-11-23
CZ301017B6 (cs) 2009-10-14
MY129227A (en) 2007-03-30
ES2621653T3 (es) 2017-07-04
CA2325371A1 (en) 2000-03-02
CA2325371C (en) 2004-08-17
PT1059933E (pt) 2003-06-30
BR9909445A (pt) 2000-12-12
ES2190244T3 (es) 2003-07-16
HUP0101594A3 (en) 2002-01-28
HU1200430D0 (hu) 2001-11-28
PL343595A1 (en) 2001-08-27
EP1059933B1 (en) 2003-01-15
ID29039A (id) 2001-07-26
NO323984B1 (no) 2007-07-30
ES2549551T3 (es) 2017-11-27
ES2549551T1 (es) 2015-10-29
PT1769804E (pt) 2012-11-13
HRP20000755A2 (en) 2001-02-28
AU5575099A (en) 2000-03-14
US20050197294A1 (en) 2005-09-08
DE69904918D1 (de) 2003-02-20
CZ20004134A3 (cs) 2001-08-15
NO20005947L (no) 2000-11-24
ATE231000T1 (de) 2003-02-15
PT2907522T (pt) 2017-10-23
PE20001089A1 (es) 2000-11-04
EP2266598A1 (en) 2010-12-29
CY1119552T1 (el) 2018-03-07
DK2907522T3 (da) 2017-10-23
DZ2873A1 (fr) 2003-12-15
KR20010072763A (ko) 2001-07-31
PT2266598T (pt) 2017-05-02
TR200003455T2 (tr) 2001-06-21
IL138829A0 (en) 2001-10-31
CN1205997C (zh) 2005-06-15
JP2002523375A (ja) 2002-07-30
DE69904918T2 (de) 2003-11-13
TW576747B (en) 2004-02-21
DK1059933T3 (da) 2003-04-07
EA003362B1 (ru) 2003-04-24
EP2907522B1 (en) 2017-08-02
NO20072983L (no) 2000-11-24
DK2266598T3 (da) 2017-05-15
WO2000010596A1 (en) 2000-03-02
HU230697B1 (hu) 2017-09-28
DK2907522T1 (da) 2015-10-19

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