JP2002508191A - 診断用核酸リガンドバイオチップ - Google Patents
診断用核酸リガンドバイオチップInfo
- Publication number
- JP2002508191A JP2002508191A JP2000539172A JP2000539172A JP2002508191A JP 2002508191 A JP2002508191 A JP 2002508191A JP 2000539172 A JP2000539172 A JP 2000539172A JP 2000539172 A JP2000539172 A JP 2000539172A JP 2002508191 A JP2002508191 A JP 2002508191A
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- biochip
- target molecule
- acid ligand
- target
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/11—Compounds covalently bound to a solid support
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/924—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis using nanostructure as support of dna analysis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/990,436 US6242246B1 (en) | 1997-12-15 | 1997-12-15 | Nucleic acid ligand diagnostic Biochip |
| US08/990,436 | 1997-12-15 | ||
| PCT/US1998/026515 WO1999031275A1 (en) | 1997-12-15 | 1998-12-14 | Nucleic acid ligand diagnostic biochip |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009010592A Division JP2009159965A (ja) | 1997-12-15 | 2009-01-21 | 診断用核酸リガンドバイオチップ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002508191A true JP2002508191A (ja) | 2002-03-19 |
| JP2002508191A5 JP2002508191A5 (enExample) | 2007-03-22 |
Family
ID=25536149
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000539172A Pending JP2002508191A (ja) | 1997-12-15 | 1998-12-14 | 診断用核酸リガンドバイオチップ |
| JP2009010592A Pending JP2009159965A (ja) | 1997-12-15 | 2009-01-21 | 診断用核酸リガンドバイオチップ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009010592A Pending JP2009159965A (ja) | 1997-12-15 | 2009-01-21 | 診断用核酸リガンドバイオチップ |
Country Status (9)
| Country | Link |
|---|---|
| US (9) | US6242246B1 (enExample) |
| EP (2) | EP1040203B1 (enExample) |
| JP (2) | JP2002508191A (enExample) |
| KR (1) | KR100603115B1 (enExample) |
| AT (1) | ATE530665T1 (enExample) |
| AU (1) | AU754956B2 (enExample) |
| CA (1) | CA2312429C (enExample) |
| DK (1) | DK2280083T3 (enExample) |
| WO (1) | WO1999031275A1 (enExample) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004087919A1 (ja) * | 2003-03-28 | 2004-10-14 | National Institute Of Advanced Industrial Science And Technology | マイクロアレイを用いたアプタマーの取得方法 |
| JP2007064927A (ja) * | 2005-09-02 | 2007-03-15 | Nipro Corp | 定性反応用試験片 |
| JP2009063590A (ja) * | 2001-03-19 | 2009-03-26 | Gyros Patent Ab | 反応可変要素の特徴付け |
| JP2014050398A (ja) * | 2007-07-17 | 2014-03-20 | Somalogic Inc | 試験試料の多重化分析 |
| JPWO2013141291A1 (ja) * | 2012-03-23 | 2015-08-03 | Necソリューションイノベータ株式会社 | ストレプトアビジンの分析用デバイスおよび分析方法 |
| US9880174B2 (en) | 2012-03-23 | 2018-01-30 | Nec Solution Innovators, Ltd. | Device and method for analyzing target |
| US10012644B2 (en) | 2012-03-30 | 2018-07-03 | Kyocera Corporation | Sensor, detection method, detection system, and detection device |
Families Citing this family (290)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6232071B1 (en) * | 1990-06-11 | 2001-05-15 | Gilead Sciences, Inc. | Tenascin-C nucleic acid ligands |
| US20070166741A1 (en) * | 1998-12-14 | 2007-07-19 | Somalogic, Incorporated | Multiplexed analyses of test samples |
| US6242246B1 (en) * | 1997-12-15 | 2001-06-05 | Somalogic, Inc. | Nucleic acid ligand diagnostic Biochip |
| GB9811465D0 (en) * | 1998-05-29 | 1998-07-29 | Tisdale Michael J | Glycoproteins having lipid mobilising properties and therapeutic applications thereof |
| AU5492499A (en) * | 1998-08-21 | 2000-03-14 | University Of Virginia Patent Foundation | Signal generating oligonucleotide-based biosensor |
| EP1405666B1 (de) | 1998-08-28 | 2007-03-21 | febit biotech GmbH | Träger für Analytbestimmungsverfahren und Verfahren zur Herstellung des Trägers |
| US20060172925A1 (en) * | 1998-10-26 | 2006-08-03 | Board Of Regents, The University Of Texas System | Thio-siRNA aptamers |
| US20040242521A1 (en) * | 1999-10-25 | 2004-12-02 | Board Of Regents, The University Of Texas System | Thio-siRNA aptamers |
| US6867289B1 (en) * | 1998-10-26 | 2005-03-15 | Board Of Regents, The University Of Texas Systems | Thio-modified aptamer synthetic methods and compositions |
| US6142681A (en) | 1999-02-22 | 2000-11-07 | Vialogy Corporation | Method and apparatus for interpreting hybridized bioelectronic DNA microarray patterns using self-scaling convergent reverberant dynamics |
| US6136541A (en) | 1999-02-22 | 2000-10-24 | Vialogy Corporation | Method and apparatus for analyzing hybridized biochip patterns using resonance interactions employing quantum expressor functions |
| US7638464B2 (en) * | 1999-04-26 | 2009-12-29 | Biocept, Inc. | Three dimensional format biochips |
| US6680377B1 (en) | 1999-05-14 | 2004-01-20 | Brandeis University | Nucleic acid-based detection |
| AU775563B2 (en) * | 1999-05-14 | 2004-08-05 | Brandeis University | Nucleic acid-based detection |
| US7074586B1 (en) * | 1999-06-17 | 2006-07-11 | Source Precision Medicine, Inc. | Quantitative assay for low abundance molecules |
| CA2379711A1 (en) | 1999-07-02 | 2001-01-25 | Conceptual Mindworks, Inc | Organic semiconductor recognition complex and system |
| US7005260B1 (en) | 2000-01-28 | 2006-02-28 | Gilead Sciences, Inc. | Tenascin-C nucleic acid ligands |
| US6506887B1 (en) * | 1999-07-29 | 2003-01-14 | Somalogic, Incorporated | Conditional-selex |
| GB9923146D0 (en) * | 1999-09-30 | 1999-12-01 | Imperial College | Detector array |
| DE19950969A1 (de) * | 1999-10-22 | 2001-05-10 | Aventis Res & Tech Gmbh & Co | Doppelstrang-Nukleinsäure-Sonden und deren Verwendung |
| US20030087265A1 (en) * | 2000-01-21 | 2003-05-08 | Edward Sauter | Specific microarrays for breast cancer screening |
| ATE360707T1 (de) * | 2000-02-07 | 2007-05-15 | Remedios Cristobal Guiller Dos | Biomolekularer toxizitätstest |
| WO2001079562A1 (en) * | 2000-04-18 | 2001-10-25 | Gilead Sciences, Inc. | Aptamer based two-site binding assay |
| US20030207271A1 (en) * | 2000-06-30 | 2003-11-06 | Holwitt Eric A. | Methods and compositions for biological sensors |
| DE50109504D1 (de) * | 2000-07-10 | 2006-05-24 | Bolivar Peter Haring | Verfahren zum nachweis von polynucleotidsequenzen |
| AU2001281730A1 (en) * | 2000-07-26 | 2002-02-05 | Chemometec A/S | Spatially resolved enzyme-linked assay |
| US6376190B1 (en) | 2000-09-22 | 2002-04-23 | Somalogic, Inc. | Modified SELEX processes without purified protein |
| DE10051396A1 (de) | 2000-10-17 | 2002-04-18 | Febit Ferrarius Biotech Gmbh | Verfahren und Vorrichtung zur integrierten Synthese und Analytbestimmung an einem Träger |
| US7351575B2 (en) * | 2000-11-08 | 2008-04-01 | Surface Logix, Inc. | Methods for processing biological materials using peelable and resealable devices |
| NZ527679A (en) * | 2001-02-07 | 2005-07-29 | Invitrogen Corp | Nucleic acid Ter-(termination sequence) sites and Ter-binding proteins or RTPs in vitro and in vivo or combinations thereof |
| KR20020067256A (ko) * | 2001-02-16 | 2002-08-22 | (주)지노믹트리 | 챔버슬라이드로 바이오 폴리머를 구획화하여 집적시키는마이크로어레이 시스템 |
| US6949377B2 (en) * | 2001-03-05 | 2005-09-27 | Ho Winston Z | Chemiluminescence-based microfluidic biochip |
| DE10113711A1 (de) * | 2001-03-16 | 2002-09-26 | Lifebits Ag | Verfahren zum Nachweis biochemischer Reaktionen und Messträger zur Durchführung des Verfahrens |
| US7572642B2 (en) * | 2001-04-18 | 2009-08-11 | Ambrigen, Llc | Assay based on particles, which specifically bind with targets in spatially distributed characteristic patterns |
| US7833701B2 (en) * | 2001-05-11 | 2010-11-16 | Panasonic Corporation | Biomolecule substrate, and test and diagnosis methods and apparatuses using the same |
| PT1401853E (pt) | 2001-05-25 | 2010-12-07 | Univ Duke | Modulador de oligonucleotídeos |
| JP4201337B2 (ja) * | 2001-07-31 | 2008-12-24 | ニューヨーク・インスティテュート・オブ・テクノロジー | 固相上で分子を固定するための方法とその利用法 |
| US20040086924A1 (en) * | 2001-10-26 | 2004-05-06 | Research Development Foundation | In vitro selection of signaling aptamers |
| US20030162190A1 (en) * | 2001-11-15 | 2003-08-28 | Gorenstein David G. | Phosphoromonothioate and phosphorodithioate oligonucleotide aptamer chip for functional proteomics |
| US6916247B2 (en) * | 2001-11-23 | 2005-07-12 | Cyberscan Technology, Inc. | Modular entertainment and gaming systems |
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| US7687256B2 (en) * | 2002-04-11 | 2010-03-30 | Spire Corporation | Surface activated biochip |
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| AU2003263853A1 (en) * | 2002-08-16 | 2004-03-03 | Board Of Regents The University Of Texas System | Compositions and methods related to flavivirus envelope protein domain iii antigens |
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| WO2005003291A2 (en) * | 2002-10-16 | 2005-01-13 | Board Of Regents Of The University Of Texas System | Bead bound combinatorial oligonucleoside phosphorothioate and phosphorodithioate aptamer libraries |
| US7049073B2 (en) | 2002-10-30 | 2006-05-23 | The University Of Chicago | Double stranded nucleic acid biochips |
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| EP2360475B1 (en) * | 2003-03-27 | 2019-10-02 | Children's Hospital Medical Center | A method and kit for detecting the early onset of renal tubular cell injury |
| WO2005037053A2 (en) * | 2003-05-23 | 2005-04-28 | Board Of Regents - The University Of Texas System | High throughput screening of aptamer libraries for specific binding to proteins on viruses and other pathogens |
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| JP2009063590A (ja) * | 2001-03-19 | 2009-03-26 | Gyros Patent Ab | 反応可変要素の特徴付け |
| WO2004087919A1 (ja) * | 2003-03-28 | 2004-10-14 | National Institute Of Advanced Industrial Science And Technology | マイクロアレイを用いたアプタマーの取得方法 |
| GB2415782A (en) * | 2003-03-28 | 2006-01-04 | Nat Inst Of Advanced Ind Scien | Method of obtaining aptamer with the use of microarray |
| GB2415782B (en) * | 2003-03-28 | 2006-08-23 | Nat Inst Of Advanced Ind Scien | Method for obtaining aptamer using microarrays |
| JP2007064927A (ja) * | 2005-09-02 | 2007-03-15 | Nipro Corp | 定性反応用試験片 |
| JP2014050398A (ja) * | 2007-07-17 | 2014-03-20 | Somalogic Inc | 試験試料の多重化分析 |
| JP2016122014A (ja) * | 2007-07-17 | 2016-07-07 | ソマロジック・インコーポレーテッド | 試験試料の多重化分析 |
| JPWO2013141291A1 (ja) * | 2012-03-23 | 2015-08-03 | Necソリューションイノベータ株式会社 | ストレプトアビジンの分析用デバイスおよび分析方法 |
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Also Published As
| Publication number | Publication date |
|---|---|
| US20140296102A1 (en) | 2014-10-02 |
| HK1031401A1 (en) | 2001-06-15 |
| CA2312429C (en) | 2015-12-08 |
| KR20010033184A (ko) | 2001-04-25 |
| WO1999031275A1 (en) | 1999-06-24 |
| AU754956B2 (en) | 2002-11-28 |
| EP1040203A1 (en) | 2000-10-04 |
| US6544776B1 (en) | 2003-04-08 |
| US6503715B1 (en) | 2003-01-07 |
| EP1040203A4 (en) | 2004-09-22 |
| JP2009159965A (ja) | 2009-07-23 |
| EP1040203B1 (en) | 2011-10-26 |
| US20070166742A1 (en) | 2007-07-19 |
| US20100209935A1 (en) | 2010-08-19 |
| US20160265038A1 (en) | 2016-09-15 |
| EP2280083B1 (en) | 2013-06-19 |
| US20030162216A1 (en) | 2003-08-28 |
| US7709192B2 (en) | 2010-05-04 |
| EP2280083A1 (en) | 2011-02-02 |
| ATE530665T1 (de) | 2011-11-15 |
| US6242246B1 (en) | 2001-06-05 |
| CA2312429A1 (en) | 1999-06-24 |
| AU1823199A (en) | 1999-07-05 |
| KR100603115B1 (ko) | 2006-07-20 |
| DK2280083T3 (da) | 2013-09-30 |
| US6458543B1 (en) | 2002-10-01 |
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