JP2001507350A5 - - Google Patents

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Publication number
JP2001507350A5
JP2001507350A5 JP1998528669A JP52866998A JP2001507350A5 JP 2001507350 A5 JP2001507350 A5 JP 2001507350A5 JP 1998528669 A JP1998528669 A JP 1998528669A JP 52866998 A JP52866998 A JP 52866998A JP 2001507350 A5 JP2001507350 A5 JP 2001507350A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998528669A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001507350A (ja
JP4324652B2 (ja
Filing date
Publication date
Priority claimed from SE9604785A external-priority patent/SE9604785D0/xx
Priority claimed from SE9702535A external-priority patent/SE9702535D0/xx
Application filed filed Critical
Priority claimed from PCT/SE1997/002050 external-priority patent/WO1998028275A1/en
Publication of JP2001507350A publication Critical patent/JP2001507350A/ja
Publication of JP2001507350A5 publication Critical patent/JP2001507350A5/ja
Application granted granted Critical
Publication of JP4324652B2 publication Critical patent/JP4324652B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP52866998A 1996-12-20 1997-12-09 鎮痛効果を有する新規な化合物 Expired - Fee Related JP4324652B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SE9604785A SE9604785D0 (sv) 1996-12-20 1996-12-20 New compounds
SE9604785-7 1996-12-20
SE9702535-7 1997-07-01
SE9702535A SE9702535D0 (sv) 1997-07-01 1997-07-01 New compounds
PCT/SE1997/002050 WO1998028275A1 (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect

Publications (3)

Publication Number Publication Date
JP2001507350A JP2001507350A (ja) 2001-06-05
JP2001507350A5 true JP2001507350A5 (enExample) 2005-08-11
JP4324652B2 JP4324652B2 (ja) 2009-09-02

Family

ID=26662830

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52866998A Expired - Fee Related JP4324652B2 (ja) 1996-12-20 1997-12-09 鎮痛効果を有する新規な化合物

Country Status (28)

Country Link
US (5) US6187792B1 (enExample)
EP (1) EP0946511B1 (enExample)
JP (1) JP4324652B2 (enExample)
KR (1) KR100549144B1 (enExample)
CN (2) CN1146540C (enExample)
AR (1) AR010376A1 (enExample)
AT (1) ATE296288T1 (enExample)
AU (1) AU737999B2 (enExample)
BR (1) BR9714055B1 (enExample)
CA (1) CA2274074C (enExample)
CZ (1) CZ295557B6 (enExample)
DE (1) DE69733362T2 (enExample)
EE (1) EE03824B1 (enExample)
ES (1) ES2241060T3 (enExample)
HU (1) HU226724B1 (enExample)
ID (1) ID22074A (enExample)
IL (2) IL130535A0 (enExample)
IS (1) IS2210B (enExample)
MY (1) MY119403A (enExample)
NO (1) NO313670B1 (enExample)
NZ (1) NZ336029A (enExample)
PL (1) PL189196B1 (enExample)
PT (1) PT946511E (enExample)
RU (1) RU2193029C2 (enExample)
SK (1) SK283211B6 (enExample)
TR (1) TR199901417T2 (enExample)
TW (1) TW548271B (enExample)
WO (1) WO1998028275A1 (enExample)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
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SE9504661D0 (sv) 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
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TW548271B (en) * 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
US6436959B1 (en) 1998-12-23 2002-08-20 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)]aminobenzamides
US6635661B2 (en) 2000-05-25 2003-10-21 Sepracor Inc. Heterocyclic analgesic compounds and methods of use thereof
US6677332B1 (en) 1999-05-25 2004-01-13 Sepracor, Inc. Heterocyclic analgesic compounds and methods of use thereof
CA2372887A1 (en) * 1999-05-25 2000-11-30 Sepracor Inc. Heterocyclic analgesic compounds and their use
US7361666B2 (en) 1999-05-25 2008-04-22 Sepracor, Inc. Heterocyclic analgesic compounds and methods of use thereof
SE9904674D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904673D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
EP1242421A1 (en) 1999-12-22 2002-09-25 Ortho-McNeil Pharmaceutical, Inc. 4-[aryl(8-azabicyclo[3.2.1] octan-3-yl)] aminobenzoic acid derivatives
AU2001232319B2 (en) * 2000-02-18 2005-01-13 Meiji Seika Kaisha, Ltd. Phenoxyalkylamine derivates useful as opioid delta receptor ligands
US6552036B2 (en) 2000-03-03 2003-04-22 Ortho-Mcneil Pharmaceutical, Inc. 3-(Diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives
US6790854B2 (en) 2000-03-24 2004-09-14 Meiji Seika Kaisha, Ltd. Diphenylalkylamine derivatives useful as opioid receptor agonists
SE0001207D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
SE0001209D0 (sv) 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
SE0001208D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
AU2001216218A1 (en) 2000-05-25 2001-12-11 Sepracor, Inc. Heterocyclic analgesic compounds and method of use thereof
US6887876B2 (en) 2000-12-14 2005-05-03 Ortho-Mcneil Pharmaceutical, Inc. Benzamidine derivatives
SE0101766D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101773D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101770D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101765D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
DE60230869D1 (de) 2001-05-18 2009-03-05 Astrazeneca Ab 4-(phenylpiperazinylmethyl) benzamidderivate und deren verwendung zur behandlung von schmerzen, angst oder gastrointestinalen störungen
SE0101768D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101769D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101767D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101771D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0103313D0 (sv) * 2001-10-03 2001-10-03 Astrazeneca Ab Novel compounds
NZ531679A (en) 2001-10-15 2005-02-25 Janssen Pharmaceutica Nv Novel substituted 4-phenyl-4-[1H-imidazol-2-YL]-piperidine derivatives and their use as selective non-peptide delta opioid agonists
US8575169B2 (en) * 2001-10-29 2013-11-05 Versi Group, Llc Method of treating sexual dysfunctions with delta opioid receptor agonist compounds
US8476280B2 (en) * 2002-05-09 2013-07-02 Versi Group, Llc Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists
US20040063744A1 (en) * 2002-05-28 2004-04-01 Tao Wang Indole, azaindole and related heterocyclic 4-alkenyl piperidine amides
UA77536C2 (en) * 2002-07-03 2006-12-15 Lundbeck & Co As H Secondary aminoaniline piperidines as mch1 antagonists and their use
SE0203302D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203303D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203301D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0300105D0 (sv) * 2003-01-16 2003-01-16 Astrazeneca Ab Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof
SE0300104D0 (sv) * 2003-01-16 2003-01-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0300103D0 (sv) * 2003-01-16 2003-01-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0300987D0 (sv) * 2003-04-03 2003-04-03 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
JP2006523673A (ja) * 2003-04-15 2006-10-19 ファイザー・プロダクツ・インク オピオイド受容体活性を有する３−ベンズヒドリリデン−８−アザ−ビシクロ［３．２．１］オクタン誘導体
SE0301445D0 (sv) * 2003-05-16 2003-05-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0301443D0 (sv) * 2003-05-16 2003-05-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
EP1641757A1 (en) * 2003-05-16 2006-04-05 AstraZeneca AB Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0301441D0 (sv) * 2003-05-16 2003-05-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0301442D0 (sv) * 2003-05-16 2003-05-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations therof and uses thereof
JP4730096B2 (ja) * 2003-05-20 2011-07-20 味の素株式会社 新規ピペリジン誘導体
WO2005003131A1 (en) * 2003-06-27 2005-01-13 Janssen Pharmaceutica N.V. Tricyclic delta opioid modulators
US7560589B2 (en) * 2003-07-28 2009-07-14 Smithkline Beecham Corporation Cycloalkylidene compounds as modulators of estrogen receptor
BRPI0415165A (pt) 2003-10-01 2007-01-09 Adolor Corp composto heterocìclico espirocìclico, composição farmacêutica, método para ligar receptores opióides, métodos para prevenir ou tratar dor, disfunção gastrointestinal, um distúrbio do trato urogenital, um distúrbio imunomodulatório, um distúrbio inflamatório, um distúrbio de função respiratória, ansiedade, distúrbio do humor, um distúrbio relacionado a estresse, distúrbio do sistema nervoso simpático, tosse, e um distúrbio motor, método para tratar uma lesão traumática ao sistema nervoso central, métodos para prevenir ou tratar acidente vascular, arritmia cardìaca, glaucoma, e disfunção sexual, métodos para tratar uma condição selecionada do grupo consistindo de choque, edema cerebral, isquemia cerebral, déficit cerebral após cirurgia cardìaca (bypass) e enxerto, lupus eritematoso sistêmico, doença de hodgkin, doença de sjogren, epilepsia, e rejeição em transplantes de órgão e enxertos de pele, e para tratar dependência de substáncias, métodos para melhorar a sobrevivência de órgãos e células, e cardioproteção após infarto do miocárdio, métodos para reduzir a necessidade de anestesia, para produzir ou manter um estado anestésico, derivado radiomarcado de um composto, derivado isotopicamente marcado de um composto, composto e método de diagnóstico por imagem
SE0400026D0 (sv) * 2004-01-09 2004-01-09 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0400025D0 (sv) * 2004-01-09 2004-01-09 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
EP1737853A1 (en) 2004-02-03 2007-01-03 Janssen Pharmaceutica N.V. 3-(diheteroarylmethylene)-8-azabicyclo¬3.2.1|octane and 3-((aryl)(heteroaryl)methylene)-8-azabicyclo¬3.2.1|octane derivatives
HRP20120343T1 (hr) 2004-08-02 2012-05-31 Astrazeneca Ab Derivati diarilmetil piperazina, njihovi pripravci i njihova uporaba
AU2005335481A1 (en) 2004-08-05 2007-04-19 Janssen Pharmaceutica N.V. Tricyclic delta- opioid modulators
SE0402485D0 (sv) * 2004-10-13 2004-10-13 Astrazeneca Ab Polymorph of N,N-Diethyl-4-(3-Fluorophenyl-Piperidin-4-Ylidene-Methyl)-Benzamide Hydrochloride salt
BRPI0519201A2 (pt) 2004-12-22 2008-12-30 Janssen Pharmaceutica Nv moduladores de delta-opiàide tricÍclico
EA011674B1 (ru) 2004-12-22 2009-04-28 Янссен Фармацевтика Н.В. ТРИЦИКЛИЧЕСКИЕ δ-ОПИОИДНЫЕ МОДУЛЯТОРЫ
BRPI0606402A2 (pt) 2005-01-06 2009-06-23 Janssen Pharmaceutica Nv moduladores de delta-opióide tricìclico
US7557875B2 (en) 2005-03-22 2009-07-07 Industrial Technology Research Institute High performance flexible display with improved mechanical properties having electrically modulated material mixed with binder material in a ratio between 6:1 and 0.5:1
EP1874315A2 (en) * 2005-04-14 2008-01-09 Mount Cook Biosciences, Inc. Compositions of novel opioid compounds and method of use thereof
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US7576207B2 (en) 2006-04-06 2009-08-18 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
JP5851080B2 (ja) * 2006-09-06 2016-02-03 スミス アンド ネフュー インコーポレーテッド 移行面を有するインプラントおよび関連のプロセス
MY148880A (en) 2006-10-20 2013-06-14 Astrazeneca Ab N-(2-hydroxyethyl)-n-methyl-4-(quinolin-8-yl(1-(thiazol-4-ylmethyl)piperidin-4-ylidene)methyl)benzamide, the process of making it as well as its use for the treatment of pain, anxiety and depression
BRPI0820091B1 (pt) * 2007-12-06 2018-02-06 Shell Internationale Research Maatschappij B.V. Processo para a preparação de um alquileno glicol a partir de óxido de alquileno
PT3233825T (pt) * 2014-12-19 2020-07-15 Pharmnovo Ab Derivados de diarilmetilideno-piperidina e sua utilização como agonistas do recetor opioide delta
CN108139623A (zh) * 2015-06-02 2018-06-08 康宁股份有限公司 美学表面以及具有这种表面的显示设备
CN111825654A (zh) * 2019-04-19 2020-10-27 北京酷瓴生物技术有限公司 苯甲烯哌啶衍生物及其制备方法、中间体和用途

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SE9504661D0 (sv) 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
TW548271B (en) 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
SE9604786D0 (sv) * 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
ATE306472T1 (de) 1997-12-24 2005-10-15 Ortho Mcneil Pharm Inc (4)-(aryl(piperidin-4-yl) aminobenzamidderivate die an delta-opioid rezeptor binden
SE0001207D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
SE0001208D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds

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