|
ES2615357T3
(es)
|
1996-12-06 |
2017-06-06 |
Amgen Inc. |
Terapia de combinación usando un inhibidor de IL-1 para tratar enfermedades mediadas por IL-1
|
|
US7488590B2
(en)
|
1998-10-23 |
2009-02-10 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
US6660843B1
(en)
*
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
DK2319928T3
(da)
|
1998-10-23 |
2013-06-24 |
Kirin Amgen Inc |
Dimere trombopoietiske peptidomimetika, der binder til MPL-receptor og har trombopoietisk aktivitet
|
|
AT406054B
(de)
*
|
1998-11-04 |
2000-02-25 |
Andreas Bernkop-Schnuerch |
Verfahren zur verbesserung der mucoadhäsion von polymeren sowie deren herstellung und verwendung
|
|
ES2254190T3
(es)
*
|
1999-06-21 |
2006-06-16 |
Santen Pharmaceutical Co., Ltd. |
Remedios contra la artritis deformante.
|
|
EP1200127B1
(en)
*
|
1999-07-21 |
2008-06-25 |
Omeros Corporation |
Solutions and methods for inhibition of pain, inflammation and cartilage degradation
|
|
US6808902B1
(en)
|
1999-11-12 |
2004-10-26 |
Amgen Inc. |
Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
|
|
JP2003533187A
(ja)
*
|
2000-05-03 |
2003-11-11 |
アムジエン・インコーポレーテツド |
治療薬としてのFcドメインを含む修飾ペプチド
|
|
US7324635B2
(en)
|
2000-05-04 |
2008-01-29 |
Telemaze Llc |
Branch calling and caller ID based call routing telephone features
|
|
EP2241328A1
(en)
*
|
2000-05-12 |
2010-10-20 |
Immunex Corporation |
Interleukin-1 inhibitors in the treatment of diseases
|
|
US8703126B2
(en)
|
2000-10-12 |
2014-04-22 |
Genentech, Inc. |
Reduced-viscosity concentrated protein formulations
|
|
PT1324776E
(pt)
|
2000-10-12 |
2009-12-23 |
Genentech Inc |
Formulações de proteína concentradas de viscosidade reduzida
|
|
US7087224B2
(en)
*
|
2000-10-31 |
2006-08-08 |
Amgen Inc. |
Method of treating anemia by administering IL-1ra
|
|
MY143582A
(en)
|
2001-06-26 |
2011-05-31 |
Amgent Fremont Inc |
Antibodies to opgl
|
|
US6818613B2
(en)
|
2001-11-07 |
2004-11-16 |
Ortho-Mcneil Pharmaceutical, Inc. |
Aqueous sustained-release formulations of proteins
|
|
EP1465596A1
(en)
*
|
2002-01-18 |
2004-10-13 |
Control Delivery Systems, Inc. |
Polymeric gel system for the controlled delivery of codrugs
|
|
MXPA04011470A
(es)
|
2002-05-21 |
2005-02-14 |
Amgen Inc |
Compuestos heterociclicos sustituidos y metodos de uso.
|
|
ME00204B
(me)
|
2002-09-06 |
2011-02-10 |
Medarex Llc |
Terapijsko, humano, monoklonsko anti-il-1r1antitijelo
|
|
US7429378B2
(en)
|
2003-05-13 |
2008-09-30 |
Depuy Spine, Inc. |
Transdiscal administration of high affinity anti-MMP inhibitors
|
|
US7553827B2
(en)
|
2003-08-13 |
2009-06-30 |
Depuy Spine, Inc. |
Transdiscal administration of cycline compounds
|
|
US7344716B2
(en)
|
2003-05-13 |
2008-03-18 |
Depuy Spine, Inc. |
Transdiscal administration of specific inhibitors of pro-inflammatory cytokines
|
|
US8273347B2
(en)
|
2003-05-13 |
2012-09-25 |
Depuy Spine, Inc. |
Autologous treatment of degenerated disc with cells
|
|
US8361467B2
(en)
*
|
2003-07-30 |
2013-01-29 |
Depuy Spine, Inc. |
Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints
|
|
US8895540B2
(en)
|
2003-11-26 |
2014-11-25 |
DePuy Synthes Products, LLC |
Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
|
|
PT1729810T
(pt)
|
2004-04-02 |
2018-11-22 |
Swedish Orphan Biovitrum Ab Publ |
Métodos de redução da agregação de il-ira
|
|
CN101103045B
(zh)
|
2004-09-24 |
2015-11-25 |
安姆根有限公司 |
修饰的Fc分子
|
|
WO2006073835A2
(en)
*
|
2004-12-30 |
2006-07-13 |
Genzyme Corporation |
Regiments for intra-articular viscosupplementation
|
|
EP3725299A1
(en)
*
|
2005-06-24 |
2020-10-21 |
Duke University |
A direct drug delivery system based on thermally responsive biopolymers
|
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
|
PE20070684A1
(es)
|
2005-11-14 |
2007-08-06 |
Amgen Inc |
MOLECULAS QUIMERICAS DE ANTICUERPO RANKL-PTH/PTHrP
|
|
US7833527B2
(en)
|
2006-10-02 |
2010-11-16 |
Amgen Inc. |
Methods of treating psoriasis using IL-17 Receptor A antibodies
|
|
GB0708376D0
(en)
|
2007-05-01 |
2007-06-06 |
Alligator Bioscience Ab |
Novel polypeptides and uses thereof
|
|
CN101918018B
(zh)
|
2007-11-14 |
2012-12-05 |
再生医药有限公司 |
使用白介素-1受体拮抗剂作为骨髓保护剂的方法
|
|
US8986696B2
(en)
|
2007-12-21 |
2015-03-24 |
Depuy Mitek, Inc. |
Trans-capsular administration of p38 map kinase inhibitors into orthopedic joints
|
|
PL2259774T3
(pl)
|
2008-02-27 |
2013-04-30 |
Biomet Biologics Llc |
Sposoby i kompozycje dla wprowadzania antagonisty receptora interleukiny-1
|
|
KR200451958Y1
(ko)
*
|
2008-10-09 |
2011-01-21 |
(주)에이치시티 |
모바일기기용 카드형 안테나장치
|
|
AU2010221156A1
(en)
|
2009-03-06 |
2011-09-22 |
Genentech, Inc. |
Antibody formulation
|
|
US20110052561A1
(en)
*
|
2009-08-27 |
2011-03-03 |
Biomet Biologics,LLC |
Osteolysis treatment
|
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
|
CN101690801B
(zh)
|
2009-10-26 |
2012-08-01 |
上海交通大学 |
白细胞介素-1受体拮抗剂的用途及其药物组合物
|
|
DE202009017772U1
(de)
|
2009-12-10 |
2011-04-21 |
Orthogen Ag |
Kombinationspräparate mit Cytokin-Antagonist und Corticosteroid
|
|
TW201527322A
(zh)
*
|
2011-02-08 |
2015-07-16 |
Abbvie Inc |
骨關節炎及疼痛之治療
|
|
HRP20160928T1
(hr)
|
2011-02-11 |
2016-10-07 |
Swedish Orphan Biovitrum Ab (Publ) |
Farmaceutske kompozicije koje sadrže anakinra bez citrata
|
|
WO2013016220A1
(en)
|
2011-07-22 |
2013-01-31 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
|
AU2012300815A1
(en)
|
2011-09-02 |
2014-02-20 |
Novozymes Biopharma Dk A/S |
Oral formulations containing hyaluronic acid for sustained drug release
|
|
US20140271589A1
(en)
|
2013-03-15 |
2014-09-18 |
Biomet Biologics, Llc |
Treatment of collagen defects using protein solutions
|
|
US10143725B2
(en)
|
2013-03-15 |
2018-12-04 |
Biomet Biologics, Llc |
Treatment of pain using protein solutions
|
|
US9758806B2
(en)
|
2013-03-15 |
2017-09-12 |
Biomet Biologics, Llc |
Acellular compositions for treating inflammatory disorders
|
|
US9895418B2
(en)
|
2013-03-15 |
2018-02-20 |
Biomet Biologics, Llc |
Treatment of peripheral vascular disease using protein solutions
|
|
US9878011B2
(en)
|
2013-03-15 |
2018-01-30 |
Biomet Biologics, Llc |
Treatment of inflammatory respiratory disease using biological solutions
|
|
CA2924661A1
(en)
*
|
2013-10-08 |
2015-04-16 |
Ascendis Pharma Osteoarthritis Division A/S |
Hydrogel-linked il-1ra prodrug
|
|
WO2015191783A2
(en)
|
2014-06-10 |
2015-12-17 |
Abbvie Inc. |
Biomarkers for inflammatory disease and methods of using same
|
|
CZ309295B6
(cs)
*
|
2015-03-09 |
2022-08-10 |
Contipro A.S. |
Samonosný, biodegradabilní film na bázi hydrofobizované kyseliny hyaluronové, způsob jeho přípravy a použití
|
|
WO2018022982A1
(en)
|
2016-07-29 |
2018-02-01 |
Trustees Of Boston University |
Age-associated clonal hematopoiesis accelerates cardio-metabolic disease development
|
|
EP3600441A1
(en)
|
2017-03-22 |
2020-02-05 |
Genentech, Inc. |
Hydrogel cross-linked hyaluronic acid prodrug compositions and methods
|
|
WO2019246179A1
(en)
*
|
2018-06-22 |
2019-12-26 |
The Trustees Of Columbia University In The City Of New York |
Sustained release compositions and methods for treatment of temporomandibular joint degeneration
|
|
US12403181B2
(en)
|
2018-08-13 |
2025-09-02 |
Iltoo Pharma |
Combination of interleukin-2 with an interleukin 1 inhibitor, conjugates and therapeutic uses thereof
|
|
EP3886809A4
(en)
*
|
2018-11-28 |
2022-03-30 |
Genascence Corporation |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF OSTEOARTHRITIS
|
|
CN114206366A
(zh)
*
|
2019-08-08 |
2022-03-18 |
艾维登斯医疗公司 |
基于微球的可注射塞来昔布制剂
|
|
US20250283174A1
(en)
|
2022-05-16 |
2025-09-11 |
Institut National de la Santé et de la Recherche Médicale |
Methods for assessing the exhaustion of hematopoietic stem cells induced by chronic inflammation
|