IS1856B - Indól afleiður nytsamlegar sem innanþekjuviðtaka mótlyf - Google Patents
Indól afleiður nytsamlegar sem innanþekjuviðtaka mótlyfInfo
- Publication number
- IS1856B IS1856B IS4838A IS4838A IS1856B IS 1856 B IS1856 B IS 1856B IS 4838 A IS4838 A IS 4838A IS 4838 A IS4838 A IS 4838A IS 1856 B IS1856 B IS 1856B
- Authority
- IS
- Iceland
- Prior art keywords
- receptor antagonists
- indole derivatives
- derivatives useful
- epithelial receptor
- epithelial
- Prior art date
Links
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9609641.7A GB9609641D0 (en) | 1996-05-09 | 1996-05-09 | Compounds useful in therapy |
| PCT/EP1997/001882 WO1997043260A1 (en) | 1996-05-09 | 1997-04-11 | Indole derivatives useful as endothelin receptor antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IS4838A IS4838A (is) | 1998-08-28 |
| IS1856B true IS1856B (is) | 2003-02-21 |
Family
ID=10793387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS4838A IS1856B (is) | 1996-05-09 | 1998-08-28 | Indól afleiður nytsamlegar sem innanþekjuviðtaka mótlyf |
Country Status (42)
| Country | Link |
|---|---|
| US (4) | US6017945A (is) |
| EP (1) | EP0901470B1 (is) |
| JP (1) | JP3245179B2 (is) |
| KR (1) | KR100331217B1 (is) |
| CN (1) | CN1124262C (is) |
| AP (1) | AP830A (is) |
| AR (1) | AR007030A1 (is) |
| AT (1) | ATE263151T1 (is) |
| AU (1) | AU717849B2 (is) |
| BG (1) | BG102873A (is) |
| BR (1) | BR9709072A (is) |
| CA (1) | CA2253876A1 (is) |
| CO (1) | CO4650036A1 (is) |
| CZ (1) | CZ292928B6 (is) |
| DE (1) | DE69728392T2 (is) |
| DK (1) | DK0901470T3 (is) |
| DZ (1) | DZ2227A1 (is) |
| EA (1) | EA001471B1 (is) |
| ES (1) | ES2218675T3 (is) |
| GB (1) | GB9609641D0 (is) |
| HN (1) | HN1997000058A (is) |
| HR (1) | HRP970249B1 (is) |
| HU (1) | HUP9901245A3 (is) |
| ID (1) | ID16878A (is) |
| IL (1) | IL125903A0 (is) |
| IS (1) | IS1856B (is) |
| MA (1) | MA26428A1 (is) |
| NO (1) | NO312547B1 (is) |
| NZ (1) | NZ332640A (is) |
| OA (1) | OA10896A (is) |
| PE (1) | PE65098A1 (is) |
| PL (1) | PL329725A1 (is) |
| PT (1) | PT901470E (is) |
| SI (1) | SI0901470T1 (is) |
| SK (1) | SK150398A3 (is) |
| TN (1) | TNSN97078A1 (is) |
| TR (1) | TR199802269T2 (is) |
| TW (1) | TW491838B (is) |
| UA (1) | UA50767C2 (is) |
| UY (1) | UY24546A1 (is) |
| WO (1) | WO1997043260A1 (is) |
| ZA (1) | ZA973963B (is) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9722287D0 (en) | 1997-10-22 | 1997-12-17 | Pfizer Ltd | Compounds useful in therapy |
| HK1041212B (en) | 1999-02-10 | 2005-12-02 | Astrazeneca Ab | Quinazoline derivatives as angiogenesis inhibitors |
| GB0016162D0 (en) * | 2000-06-30 | 2000-08-23 | Cancer Res Campaign Tech | Indole-3-acetic acid derivatives |
| US20050203166A1 (en) * | 2000-06-30 | 2005-09-15 | Cancer Research Technology Limited | Indole-3-acetic acid derivatives |
| WO2003000253A1 (en) | 2001-06-20 | 2003-01-03 | Wyeth | Substituted indole acid derivatives as inhibitors of plasminogen activator inhibitor-1 (pai-1) |
| TWI224101B (en) | 2001-06-20 | 2004-11-21 | Wyeth Corp | Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1) |
| AR037097A1 (es) | 2001-10-05 | 2004-10-20 | Novartis Ag | Compuestos acilsulfonamidas, composiciones farmaceuticas y el uso de dichos compuestos para la preparacion de un medicamento |
| ATE331709T1 (de) | 2002-12-10 | 2006-07-15 | Wyeth Corp | Substituierte 3-carbonyl-1-yl essigsäure derivate als plasminogen aktivator inhibitor(pai-1) inhibitoren |
| DE60306547T2 (de) | 2002-12-10 | 2007-06-28 | Wyeth | Substituierte 3-alkyl- und 3-arylalkyl-1h-indol-1-yl-essigsäure-derivate als plasminogen-aktivator |
| ATE411288T1 (de) | 2002-12-10 | 2008-10-15 | Wyeth Corp | Aryl-, aryloxy- und alkyloxysubstituierte 1h- indol-3-yl-glyoxylsäurederivateals inhibitoren des plasminogenaktivatorinhibitors-1 (pai-1) |
| UA80453C2 (en) | 2002-12-10 | 2007-09-25 | Derivatives of substituted dyhydropyranoindol-3,4-dion as inhibitors of plasminogen activator inhibitor-1 (pai-1) | |
| ATE430731T1 (de) | 2002-12-10 | 2009-05-15 | Wyeth Corp | Substituierte indoloxoacetylaminoessigsäurederivate als inhibitoren des plasminogenaktivatorinhibitors-1 (pai-1) |
| WO2004067529A1 (en) * | 2003-01-22 | 2004-08-12 | Eli Lilly And Company | Indole-derivative modulators of steroid hormone nuclear receptors |
| US7342039B2 (en) | 2003-09-25 | 2008-03-11 | Wyeth | Substituted indole oximes |
| US7351726B2 (en) | 2003-09-25 | 2008-04-01 | Wyeth | Substituted oxadiazolidinediones |
| US7446201B2 (en) | 2003-09-25 | 2008-11-04 | Wyeth | Substituted heteroaryl benzofuran acids |
| US7141592B2 (en) | 2003-09-25 | 2006-11-28 | Wyeth | Substituted oxadiazolidinediones |
| US7442805B2 (en) | 2003-09-25 | 2008-10-28 | Wyeth | Substituted sulfonamide-indoles |
| US7163954B2 (en) | 2003-09-25 | 2007-01-16 | Wyeth | Substituted naphthyl benzothiophene acids |
| US7268159B2 (en) | 2003-09-25 | 2007-09-11 | Wyeth | Substituted indoles |
| US7420083B2 (en) | 2003-09-25 | 2008-09-02 | Wyeth | Substituted aryloximes |
| US7265148B2 (en) | 2003-09-25 | 2007-09-04 | Wyeth | Substituted pyrrole-indoles |
| US7534894B2 (en) | 2003-09-25 | 2009-05-19 | Wyeth | Biphenyloxy-acids |
| US7582773B2 (en) | 2003-09-25 | 2009-09-01 | Wyeth | Substituted phenyl indoles |
| US7411083B2 (en) | 2003-09-25 | 2008-08-12 | Wyeth | Substituted acetic acid derivatives |
| US7332521B2 (en) | 2003-09-25 | 2008-02-19 | Wyeth | Substituted indoles |
| JP2005109006A (ja) * | 2003-09-29 | 2005-04-21 | Tdk Corp | 高電圧貫通型コンデンサ及びマグネトロン |
| HN2004000536A (es) | 2003-12-16 | 2009-02-18 | Wyeth Corp | Un procediemiento de sintesis para la alquilacion reductiva de la posicon c-3 de indoles |
| JP2008510816A (ja) | 2004-08-23 | 2008-04-10 | ワイス | チアゾロ−ナフチル酸 |
| CA2577782A1 (en) | 2004-08-23 | 2006-03-02 | Wyeth | Pyrrolo-naphthyl acids as pai-1 inhibitors |
| RU2007106868A (ru) | 2004-08-23 | 2008-09-27 | Вайет (Us) | Оксазол-нафтиловые кислоты и их применение в качестве модуляторов ингибитора активатора плазминогена-1 (pai) для лечения тромбоза и сердечно-сосудистых заболеваний |
| MX2008002117A (es) | 2005-08-17 | 2008-09-26 | Wyeth Corp | Indoles sustituidos y metodos de uso de estos. |
| AU2007237874A1 (en) * | 2006-04-13 | 2007-10-25 | Actelion Pharmaceuticals Ltd | Endothelin receptor antagonists for early stage idiopathic pulmonary fibrosis |
| DE102008030207A1 (de) | 2008-06-25 | 2009-12-31 | Bayer Schering Pharma Aktiengesellschaft | Substituierte 7-Sulfanylmethyl-, 7-Sulfinylmethyl- und 7-Sulfonylmethyl-Indole und ihre Verwendung |
| DE102008030206A1 (de) | 2008-06-25 | 2009-12-31 | Bayer Schering Pharma Aktiengesellschaft | 3-Cyanoalky- und 3-Hydroxyalkyl-Indole und ihre Verwendung |
| US12343337B2 (en) | 2016-09-29 | 2025-07-01 | The Regents Of The University Of California | Compounds for increasing neural plasticity |
| CN106674065A (zh) * | 2016-12-07 | 2017-05-17 | 贵州大学 | 一种5‑卤代‑2‑烷氧基‑4‑甲苯磺酰氯制备方法 |
| GB201817038D0 (en) * | 2018-10-19 | 2018-12-05 | Inflazome Ltd | Novel processes |
| EP3931189A4 (en) | 2019-02-27 | 2022-11-30 | The Regents Of The University Of California | Azepino-indoles and other heterocycles for treating brain disorders |
| EP4448531A1 (en) | 2021-12-15 | 2024-10-23 | Delix Therapeutics, Inc. | Phenoxy and benzyloxy substituted psychoplastogens and uses thereof |
| CN117263832A (zh) * | 2023-08-18 | 2023-12-22 | 辽宁龙田化工科技有限公司 | 一种2-氯-4-甲磺酰基苯甲酸合成方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE637354A (is) * | 1962-09-14 | |||
| GB1255518A (en) * | 1968-10-08 | 1971-12-01 | Sumitomo Chemical Co | 2-indolylacetic acid derivatives and process for production thereof |
| US4397079A (en) * | 1981-03-30 | 1983-08-09 | International Business Machines Corp. | Process for improving the yield of integrated devices including Schottky barrier diodes |
| US5245046A (en) * | 1988-11-14 | 1993-09-14 | The Upjohn Company | α-amino-indole-3-acetic acids useful as anti-diabetic, anti-obesity and anti-atherosclerotic agents |
| DE69118388T2 (de) | 1990-09-10 | 1996-11-14 | Rhone Poulenc Rorer Int | Substituierte bizyklische arylderivate mit selektiver leukotrien b4 antagonistischer wirkung |
| ZA939516B (en) * | 1992-12-22 | 1994-06-06 | Smithkline Beecham Corp | Endothelin receptor antagonists |
| ATE189217T1 (de) * | 1993-03-19 | 2000-02-15 | Merck & Co Inc | Phenoxyphenylessigsäurederivate |
| GB9317096D0 (en) * | 1993-08-17 | 1993-09-29 | Pfizer Ltd | Indoles |
-
1996
- 1996-05-09 GB GBGB9609641.7A patent/GB9609641D0/en active Pending
-
1997
- 1997-04-01 TW TW086104171A patent/TW491838B/zh not_active IP Right Cessation
- 1997-04-11 DE DE1997628392 patent/DE69728392T2/de not_active Expired - Fee Related
- 1997-04-11 TR TR1998/02269T patent/TR199802269T2/xx unknown
- 1997-04-11 HU HU9901245A patent/HUP9901245A3/hu unknown
- 1997-04-11 NZ NZ332640A patent/NZ332640A/en unknown
- 1997-04-11 ES ES97920690T patent/ES2218675T3/es not_active Expired - Lifetime
- 1997-04-11 AU AU26978/97A patent/AU717849B2/en not_active Ceased
- 1997-04-11 US US09/147,096 patent/US6017945A/en not_active Expired - Fee Related
- 1997-04-11 EA EA199800908A patent/EA001471B1/ru not_active IP Right Cessation
- 1997-04-11 KR KR1019980709023A patent/KR100331217B1/ko not_active Expired - Fee Related
- 1997-04-11 PL PL97329725A patent/PL329725A1/xx unknown
- 1997-04-11 AT AT97920690T patent/ATE263151T1/de not_active IP Right Cessation
- 1997-04-11 IL IL12590397A patent/IL125903A0/xx unknown
- 1997-04-11 CZ CZ19983582A patent/CZ292928B6/cs not_active IP Right Cessation
- 1997-04-11 UA UA98115906A patent/UA50767C2/uk unknown
- 1997-04-11 BR BR9709072A patent/BR9709072A/pt active Search and Examination
- 1997-04-11 CN CN97194016A patent/CN1124262C/zh not_active Expired - Fee Related
- 1997-04-11 SI SI9730646T patent/SI0901470T1/xx unknown
- 1997-04-11 WO PCT/EP1997/001882 patent/WO1997043260A1/en active IP Right Grant
- 1997-04-11 DK DK97920690T patent/DK0901470T3/da active
- 1997-04-11 JP JP54042397A patent/JP3245179B2/ja not_active Expired - Fee Related
- 1997-04-11 CA CA002253876A patent/CA2253876A1/en not_active Abandoned
- 1997-04-11 SK SK1503-98A patent/SK150398A3/sk unknown
- 1997-04-11 EP EP97920690A patent/EP0901470B1/en not_active Expired - Lifetime
- 1997-04-11 PT PT97920690T patent/PT901470E/pt unknown
- 1997-04-29 HN HN1997000058A patent/HN1997000058A/es unknown
- 1997-05-02 PE PE1997000345A patent/PE65098A1/es not_active Application Discontinuation
- 1997-05-07 TN TNTNSN97078A patent/TNSN97078A1/fr unknown
- 1997-05-07 CO CO97024471A patent/CO4650036A1/es unknown
- 1997-05-07 UY UY24546A patent/UY24546A1/es not_active IP Right Cessation
- 1997-05-07 MA MA24599A patent/MA26428A1/fr unknown
- 1997-05-07 DZ DZ970074A patent/DZ2227A1/fr active
- 1997-05-07 ID IDP971517A patent/ID16878A/id unknown
- 1997-05-07 AR ARP970101888A patent/AR007030A1/es not_active Application Discontinuation
- 1997-05-08 AP APAP/P/1997/000982A patent/AP830A/en active
- 1997-05-08 ZA ZA973963A patent/ZA973963B/xx unknown
- 1997-05-09 HR HR970249A patent/HRP970249B1/xx not_active IP Right Cessation
-
1998
- 1998-08-28 IS IS4838A patent/IS1856B/is unknown
- 1998-10-09 OA OA9800192A patent/OA10896A/en unknown
- 1998-10-27 BG BG102873A patent/BG102873A/xx unknown
- 1998-11-09 NO NO19985225A patent/NO312547B1/no not_active IP Right Cessation
-
1999
- 1999-10-07 US US09/414,361 patent/US6136843A/en not_active Expired - Fee Related
-
2000
- 2000-04-24 US US09/556,651 patent/US6306852B1/en not_active Expired - Fee Related
-
2001
- 2001-01-09 US US09/756,835 patent/US6384070B2/en not_active Expired - Fee Related
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