IN2015DN01119A - - Google Patents

Info

Publication number
IN2015DN01119A
IN2015DN01119A IN1119DEN2015A IN2015DN01119A IN 2015DN01119 A IN2015DN01119 A IN 2015DN01119A IN 1119DEN2015 A IN1119DEN2015 A IN 1119DEN2015A IN 2015DN01119 A IN2015DN01119 A IN 2015DN01119A
Authority
IN
India
Prior art keywords
compounds
disclosed
methods
intermediates
synthesis
Prior art date
Application number
Other languages
English (en)
Inventor
Ende Christopher William Am
Michael Eric Green
Douglas Scott Johnson
Gregory Wayne Kauffman
Christopher John Odonnell
Nandini Chaturbhai Patel
Martin Youngjin Pettersson
Antonia Friederike Stepan
Cory Michael Stiff
Chakrapani Subramanyam
Tuan Phong Tran
Patrick Robert Verhoest
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IN2015DN01119A publication Critical patent/IN2015DN01119A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epidemiology (AREA)
IN1119DEN2015 2012-09-21 2013-09-06 IN2015DN01119A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261703969P 2012-09-21 2012-09-21
PCT/IB2013/058347 WO2014045156A1 (en) 2012-09-21 2013-09-06 Novel bicyclic pyridinones

Publications (1)

Publication Number Publication Date
IN2015DN01119A true IN2015DN01119A (zh) 2015-06-26

Family

ID=49585452

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1119DEN2015 IN2015DN01119A (zh) 2012-09-21 2013-09-06

Country Status (47)

Country Link
US (3) US8916564B2 (zh)
EP (1) EP2897956B1 (zh)
JP (1) JP5844018B2 (zh)
KR (1) KR101725696B1 (zh)
CN (1) CN104662021B (zh)
AP (1) AP2015008277A0 (zh)
AR (1) AR092628A1 (zh)
AU (1) AU2013319845B2 (zh)
BR (1) BR112015006436A2 (zh)
CA (1) CA2882386C (zh)
CL (1) CL2015000717A1 (zh)
CR (1) CR20150053A (zh)
CU (1) CU20150021A7 (zh)
CY (1) CY1118662T1 (zh)
DK (1) DK2897956T3 (zh)
DO (1) DOP2015000069A (zh)
EA (1) EA026668B1 (zh)
EC (1) ECSP15015594A (zh)
ES (1) ES2609987T3 (zh)
GE (1) GEP201706659B (zh)
GT (1) GT201500069A (zh)
HK (1) HK1206013A1 (zh)
HR (1) HRP20161558T1 (zh)
HU (1) HUE031248T2 (zh)
IL (1) IL237163A (zh)
IN (1) IN2015DN01119A (zh)
LT (1) LT2897956T (zh)
MA (1) MA37886B1 (zh)
MD (1) MD4583B1 (zh)
ME (1) ME02571B (zh)
MX (1) MX360599B (zh)
MY (1) MY181891A (zh)
NI (1) NI201500038A (zh)
NZ (1) NZ704863A (zh)
PE (1) PE20150686A1 (zh)
PH (1) PH12015500376B1 (zh)
PL (1) PL2897956T3 (zh)
PT (1) PT2897956T (zh)
RS (1) RS55426B1 (zh)
SG (1) SG11201501074WA (zh)
SI (1) SI2897956T1 (zh)
TN (1) TN2015000084A1 (zh)
TW (1) TWI500616B (zh)
UA (1) UA110688C2 (zh)
UY (1) UY35039A (zh)
WO (1) WO2014045156A1 (zh)
ZA (1) ZA201501195B (zh)

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WO2014111457A1 (en) 2013-01-17 2014-07-24 Janssen Pharmaceutica Nv Novel substituted pyrido-piperazinone derivatives as gamma secretase modulators
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US10562897B2 (en) 2014-01-16 2020-02-18 Janssen Pharmaceutica Nv Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators
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RU2757276C2 (ru) 2016-12-16 2021-10-12 Пайплайн Терапьютикс, Инк. Способы лечения кохлеарной синаптопатии
EP3860562A1 (en) 2018-10-02 2021-08-11 Frequency Therapeutics, Inc. Pharmaceutical compositions comprising otic therapeutic agents and related methods
MX2021012258A (es) 2019-04-08 2022-01-04 Frequency Therapeutics Inc Combinacion de chir99021 y acido valproico para tratar la perdida auditiva.
EP4069691A1 (en) 2019-12-06 2022-10-12 Vertex Pharmaceuticals Incorporated Substituted tetrahydrofurans as modulators of sodium channels
CN113402490B (zh) * 2021-03-29 2023-01-03 白银京宇新药业有限公司 一种1，2，6，7-四氢-8H-茚并[5，4-b]呋喃-8-酮的制备方法
CA3221259A1 (en) 2021-06-04 2022-12-08 Vertex Pharmaceuticals Incorporated N-(hydroxyalkyl (hetero)aryl) tetrahydrofuran carboxamides as modulators of sodium channels
CN114034792A (zh) * 2021-11-09 2022-02-11 山东新华制药股份有限公司 检测氯酮含量的液相色谱分析方法

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