IN2014MN00258A - - Google Patents
Info
- Publication number
- IN2014MN00258A IN2014MN00258A IN258MUN2014A IN2014MN00258A IN 2014MN00258 A IN2014MN00258 A IN 2014MN00258A IN 258MUN2014 A IN258MUN2014 A IN 258MUN2014A IN 2014MN00258 A IN2014MN00258 A IN 2014MN00258A
- Authority
- IN
- India
- Prior art keywords
- compounds
- present
- novel
- medicament
- concerned
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11174120 | 2011-07-15 | ||
| PCT/EP2012/063667 WO2013010904A1 (en) | 2011-07-15 | 2012-07-12 | Novel substituted indole derivatives as gamma secretase modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MN00258A true IN2014MN00258A (ru) | 2015-09-25 |
Family
ID=46506432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN258MUN2014 IN2014MN00258A (ru) | 2011-07-15 | 2012-07-12 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9115143B2 (ru) |
| EP (1) | EP2731948B1 (ru) |
| JP (1) | JP6068464B2 (ru) |
| KR (1) | KR101913135B1 (ru) |
| CN (1) | CN103874702B (ru) |
| AR (1) | AR087182A1 (ru) |
| AU (1) | AU2012285931B2 (ru) |
| BR (1) | BR112014000713A2 (ru) |
| CA (1) | CA2841102C (ru) |
| EA (1) | EA023045B1 (ru) |
| ES (1) | ES2555167T3 (ru) |
| IL (1) | IL230422B (ru) |
| IN (1) | IN2014MN00258A (ru) |
| MX (1) | MX2014000626A (ru) |
| TW (1) | TWI567079B (ru) |
| WO (1) | WO2013010904A1 (ru) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102325765B (zh) | 2009-02-06 | 2014-12-24 | 杨森制药公司 | 作为γ-分泌酶调节剂的取代的双环杂环化合物 |
| AU2010262036B2 (en) | 2009-05-07 | 2014-10-30 | Cellzome Limited | Novel substituted indazole and aza-indazole derivatives as gamma secretase modulators |
| AP2011006034A0 (en) | 2009-07-15 | 2011-12-31 | Janssen Pharmaceuticals Inc | Substituted triazole and imidazole derivatives as gamma secretase modulators. |
| US9145399B2 (en) | 2010-01-15 | 2015-09-29 | Janssen Pharmaceuticals, Inc. | Substituted bicyclic triazole derivatives as gamma secretase modulators |
| CN103502225B (zh) | 2011-03-24 | 2015-11-25 | 杨森制药公司 | 作为γ分泌酶调节剂的经取代的三唑基哌嗪以及三唑基哌啶衍生物 |
| EP2731948B1 (en) | 2011-07-15 | 2015-09-09 | Janssen Pharmaceuticals, Inc. | Novel substituted indole derivatives as gamma secretase modulators |
| AU2013261023B2 (en) | 2012-05-16 | 2016-11-24 | Cellzome Limited | Substituted 3, 4 - dihydro - 2H - pyrido [1, 2 -a] pyrazine - 1, 6 - dione derivatives useful for the treatment of (inter alia) Alzheimer's disease |
| EP2738172A1 (en) * | 2012-11-28 | 2014-06-04 | Almirall, S.A. | New bicyclic compounds as crac channel modulators |
| EP2953949B1 (en) | 2012-12-20 | 2016-09-28 | Janssen Pharmaceutica NV | Novel tricyclic 3,4-dihydro-2h-pyrido[1,2-a]pyrazine-1,6-dione derivatives as gamma secretase modulators |
| US10246454B2 (en) | 2013-01-17 | 2019-04-02 | Janssen Pharmaceutica Nv | Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators |
| US10562897B2 (en) | 2014-01-16 | 2020-02-18 | Janssen Pharmaceutica Nv | Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators |
| GB201506660D0 (en) | 2015-04-20 | 2015-06-03 | Cellcentric Ltd | Pharmaceutical compounds |
| GB201506658D0 (en) | 2015-04-20 | 2015-06-03 | Cellcentric Ltd | Pharmaceutical compounds |
| ES2863474T3 (es) | 2016-07-30 | 2021-10-11 | Bristol Myers Squibb Co | Compuestos de indol sustituidos con dimetoxifenilo como inhibidores de TLR7, TLR8 o TLR9 |
| MA46188A (fr) | 2016-09-09 | 2019-07-17 | Bristol Myers Squibb Co | Composés indole substitués par pyridyle |
| JOP20190060A1 (ar) | 2016-09-26 | 2019-03-26 | Chugai Pharmaceutical Co Ltd | مشتق بيرازولو بيريدين له تأثير مساعد لمستقبل glp-1 |
| ES2921020T3 (es) | 2017-08-04 | 2022-08-16 | Bristol Myers Squibb Co | Compuestos de indol sustituidos con [1,2,4]triazolo[4,3-a]piridinilo |
| US11447466B2 (en) | 2017-08-04 | 2022-09-20 | Bristol-Myers Squibb Company | Substituted indole compounds useful as inhibitors of TLR7/8/9 |
| WO2019072942A1 (en) | 2017-10-11 | 2019-04-18 | F. Hoffmann-La Roche Ag | BICYCLIC COMPOUNDS FOR USE AS INHIBITORS OF KINASE RIP1 |
| KR20200086709A (ko) * | 2017-11-14 | 2020-07-17 | 브리스톨-마이어스 스큅 컴퍼니 | 치환된 인돌 화합물 |
| SG11202005628RA (en) | 2017-12-18 | 2020-07-29 | Bristol Myers Squibb Co | 4-azaindole compounds |
| EP3728253B1 (en) | 2017-12-19 | 2024-03-27 | Bristol-Myers Squibb Company | 6-azaindole compounds |
| SG11202005696YA (en) | 2017-12-19 | 2020-07-29 | Bristol Myers Squibb Co | Substituted indole compounds useful as tlr inhibitors |
| ES2922174T3 (es) | 2017-12-19 | 2022-09-09 | Bristol Myers Squibb Co | Compuestos de indol sustituidos con amida útiles como inhibidores de TLR |
| EP3728264B1 (en) | 2017-12-20 | 2021-12-01 | Bristol-Myers Squibb Company | Diazaindole compounds |
| ES2904676T3 (es) | 2017-12-20 | 2022-04-05 | Bristol Myers Squibb Co | Compuestos de amino indol útiles como inhibidores de TLR |
| AU2018393003A1 (en) | 2017-12-20 | 2020-08-06 | Bristol-Myers Squibb Company | Aryl and heteroaryl substituted indole compounds |
| CN112566696B (zh) * | 2018-09-03 | 2024-01-16 | 豪夫迈·罗氏有限公司 | 双环杂芳基衍生物 |
| EP3628669A1 (en) * | 2018-09-28 | 2020-04-01 | GenKyoTex Suisse SA | Novel compounds as nadph oxidase inhibitors |
Family Cites Families (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE172975T1 (de) * | 1992-05-19 | 1998-11-15 | Adir | Benzimidezolderivate mit antidiabetischer und anti-plättchenklumpungswirkung |
| US5767144A (en) | 1994-08-19 | 1998-06-16 | Abbott Laboratories | Endothelin antagonists |
| AU6517196A (en) | 1995-07-13 | 1997-02-10 | Knoll Aktiengesellschaft | Piperazine derivatives as therapeutic agents |
| CZ20014366A3 (cs) | 1999-06-10 | 2002-11-13 | Warner-Lambert Company | Způsob inhibice agregace amyloidních proteinů a zobrazení amyloidních usazenin za pouľití isoindolinových derivátů |
| JP2003530437A (ja) | 2000-04-13 | 2003-10-14 | マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチ | Ａβ４２低下物質 |
| WO2001087845A2 (en) | 2000-05-15 | 2001-11-22 | Fujisawa Pharmaceutical Co., Ltd. | N-containing heterocyclic compounds and their use as 5-ht antagonists |
| DE10109867A1 (de) | 2001-03-01 | 2002-09-05 | Abbott Gmbh & Co Kg | Verwendung von Triazolverbindungen zur Prophylaxe und Therapie neurodegenerativer Erkrankungen, Hirntrauma und zerebraler Ischämie |
| DE10238002A1 (de) | 2002-08-20 | 2004-03-04 | Merck Patent Gmbh | Benzimidazolderivate |
| PL378753A1 (pl) | 2003-02-27 | 2006-05-15 | F.Hoffmann-La Roche Ag | Antagoniści receptora CCR-3 |
| JP4847868B2 (ja) | 2003-05-14 | 2011-12-28 | ニューロジェネティック ファーマシューティカルズ、 インコーポレイテッド | 化合物、及び、アミロイドベータの調節におけるその使用 |
| CA2535406A1 (en) | 2003-08-14 | 2005-02-24 | F. Hoffmann-La Roche Ag | Gabanergic modulators |
| ATE483708T1 (de) | 2004-03-08 | 2010-10-15 | Prosidion Ltd | Pyrrolopyridin-2-carbonsäurehydrazide als inhibitoren von glykogenphosphorylase |
| WO2005115990A1 (ja) | 2004-05-26 | 2005-12-08 | Eisai R & D Management Co., Ltd. | シンナミド化合物 |
| EP1808432B1 (en) | 2004-10-26 | 2010-02-24 | Eisai R&D Management Co., Ltd. | Amorphous form of cinnamide compound |
| EP2457901A1 (en) * | 2005-03-14 | 2012-05-30 | High Point Pharmaceuticals, LLC | Benzazole derivatives, compositions, and methods of use as B-secretase inhibitors |
| US7572807B2 (en) | 2005-06-09 | 2009-08-11 | Bristol-Myers Squibb Company | Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors |
| AU2006293635A1 (en) | 2005-09-22 | 2007-03-29 | Sanofi-Aventis | Amino-alkyl-amide derivatives as CCR3 receptor liquids |
| US20070078136A1 (en) | 2005-09-22 | 2007-04-05 | Bristol-Myers Squibb Company | Fused heterocyclic compounds useful as kinase modulators |
| WO2007043786A1 (en) | 2005-10-10 | 2007-04-19 | Seiyang Yang | Dynamic-based verification apparatus for verification from electronic system level to gate level, and verification method using the same |
| US8017805B2 (en) | 2005-10-11 | 2011-09-13 | Chemtura Corporation | Diaromatic amines |
| AR056785A1 (es) | 2005-11-10 | 2007-10-24 | Schering Corp | COMPUESTOS DE IMIDAZO[1,2-A]PIRAZINAS, uTILES COMO INHIBIDORES, REGULADORES O MODULADORES DE PROTEINQUINASAS |
| CA2643055A1 (en) | 2006-03-13 | 2007-09-20 | Pfizer Products Inc. | Tetralines antagonists of the h-3 receptor |
| GB0606774D0 (en) | 2006-04-03 | 2006-05-10 | Novartis Ag | Organic compounds |
| US7893058B2 (en) | 2006-05-15 | 2011-02-22 | Janssen Pharmaceutica Nv | Imidazolopyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
| WO2008065199A1 (en) | 2006-12-01 | 2008-06-05 | Galapagos N.V. | Imidazolopyridine compounds useful for the treatment of degenerative and inflammatory diseases |
| AU2007332750A1 (en) | 2006-12-12 | 2008-06-19 | Schering Corporation | Aspartyl protease inhibitors containing a tricyclic ring system |
| EP2134713A2 (en) | 2006-12-20 | 2009-12-23 | Schering Corporation | Novel jnk inhibitors |
| WO2008097538A1 (en) | 2007-02-08 | 2008-08-14 | Merck & Co., Inc. | Therapeutic agents |
| CA2676920A1 (en) | 2007-02-12 | 2008-08-21 | Merck & Co., Inc. | Piperidine derivatives |
| AU2008215948A1 (en) | 2007-02-12 | 2008-08-21 | Merck & Co., Inc. | Piperazine derivatives for treatment of AD and related conditions |
| EP2155737A1 (en) | 2007-05-07 | 2010-02-24 | Schering Corporation | Gamma secretase modulators |
| CN101675045B (zh) | 2007-05-11 | 2012-11-28 | 弗·哈夫曼-拉罗切有限公司 | 作为β-淀粉样蛋白调节剂的杂芳基苯胺 |
| WO2008156580A1 (en) | 2007-06-13 | 2008-12-24 | Merck & Co., Inc. | Triazole derivatives for treating alzheimer's disease and related conditions |
| US20110053918A1 (en) | 2007-06-29 | 2011-03-03 | Zhaoning Zhu | Gamma secretase modulators |
| US7935815B2 (en) | 2007-08-31 | 2011-05-03 | Eisai R&D Management Co., Ltd. | Imidazoyl pyridine compounds and salts thereof |
| MX2010002674A (es) | 2007-09-06 | 2010-03-25 | Schering Corp | Moduladores de gamma secretasa. |
| GB0720444D0 (en) | 2007-10-18 | 2007-11-28 | Glaxo Group Ltd | Novel compounds |
| EP2229381A1 (en) | 2007-12-06 | 2010-09-22 | Schering Corporation | Gamma secretase modulators |
| MX2010006378A (es) | 2007-12-11 | 2010-09-07 | Schering Corp | Moduladores de gamma secretasa. |
| MX2010008700A (es) | 2008-02-22 | 2010-08-30 | Hoffmann La Roche | Moduladores de beta-amiloide. |
| US20100137320A1 (en) | 2008-02-29 | 2010-06-03 | Schering Corporation | Gamma secretase modulators |
| WO2010010188A1 (en) | 2008-07-25 | 2010-01-28 | Galapagos Nv | Novel compounds useful for the treatment of degenerative and inflammatory diseases. |
| US8785489B2 (en) | 2008-10-17 | 2014-07-22 | Boehringer Ingelheim International Gmbh | Heteroaryl substituted indole compounds useful as MMP-13 inhibitors |
| JP2012508182A (ja) | 2008-11-06 | 2012-04-05 | シェーリング コーポレイション | γ−セクレターゼ調節剤 |
| CN102209537A (zh) | 2008-11-10 | 2011-10-05 | 弗·哈夫曼-拉罗切有限公司 | 杂环γ分泌酶调节剂 |
| CA2744152A1 (en) | 2008-12-03 | 2010-06-10 | Via Pharmaceuticals, Inc. | Inhibitors of diacylglycerol acyltransferase |
| PA8854101A1 (es) | 2008-12-18 | 2010-07-27 | Ortho Mcneil Janssen Pharm | Derivados de imidazol bicíclicos sustituidos como moduladores de gamma secretasa |
| TW201030002A (en) | 2009-01-16 | 2010-08-16 | Bristol Myers Squibb Co | Bicyclic compounds for the reduction of beta-amyloid production |
| CN102325765B (zh) | 2009-02-06 | 2014-12-24 | 杨森制药公司 | 作为γ-分泌酶调节剂的取代的双环杂环化合物 |
| TWI461425B (zh) | 2009-02-19 | 2014-11-21 | Janssen Pharmaceuticals Inc | 作為伽瑪分泌酶調節劑之新穎經取代的苯并唑、苯并咪唑、唑并吡啶及咪唑并吡啶衍生物類 |
| JP2012051806A (ja) * | 2009-02-26 | 2012-03-15 | Eisai R & D Management Co Ltd | イミダゾリルピラジン誘導体 |
| JP2012051807A (ja) | 2009-02-26 | 2012-03-15 | Eisai R & D Management Co Ltd | アリールイミダゾール化合物 |
| CA2753696A1 (en) * | 2009-02-26 | 2010-09-02 | Noritaka Kitazawa | Nitrogen-containing fused heterocyclic compounds and their use as beta amyloid production inhibitors |
| JP2012519682A (ja) | 2009-03-03 | 2012-08-30 | ファイザー・インク | ガンマ−セクレターゼモジュレーターとしての新規フェニルイミダゾールおよびフェニルトリアゾール |
| WO2010106745A1 (ja) | 2009-03-16 | 2010-09-23 | パナソニック株式会社 | アプリケーション実行装置 |
| JP5651681B2 (ja) * | 2009-04-03 | 2015-01-14 | 大日本住友製薬株式会社 | 代謝型グルタミン酸受容体５介在障害の治療のための化合物、およびその使用方法 |
| EP2424866A1 (en) * | 2009-04-27 | 2012-03-07 | High Point Pharmaceuticals, LLC | Substituted imidazo[1,2-a]pyridine derivatives, pharmaceutical compositions, and methods of use as -secretase inhibitors |
| AU2010262036B2 (en) | 2009-05-07 | 2014-10-30 | Cellzome Limited | Novel substituted indazole and aza-indazole derivatives as gamma secretase modulators |
| JP2010274429A (ja) | 2009-05-26 | 2010-12-09 | Ihi Corp | アライメントステージ |
| AP2011006034A0 (en) | 2009-07-15 | 2011-12-31 | Janssen Pharmaceuticals Inc | Substituted triazole and imidazole derivatives as gamma secretase modulators. |
| US9145399B2 (en) | 2010-01-15 | 2015-09-29 | Janssen Pharmaceuticals, Inc. | Substituted bicyclic triazole derivatives as gamma secretase modulators |
| WO2012061342A2 (en) * | 2010-11-01 | 2012-05-10 | Arqule, Inc. | Substituted benzo-imidazo-pyrido-diazepine compounds |
| CN103502225B (zh) | 2011-03-24 | 2015-11-25 | 杨森制药公司 | 作为γ分泌酶调节剂的经取代的三唑基哌嗪以及三唑基哌啶衍生物 |
| EP2691393B1 (en) | 2011-03-31 | 2016-09-14 | Pfizer Inc | Novel bicyclic pyridinones |
| EP2731948B1 (en) | 2011-07-15 | 2015-09-09 | Janssen Pharmaceuticals, Inc. | Novel substituted indole derivatives as gamma secretase modulators |
-
2012
- 2012-07-12 EP EP12733754.1A patent/EP2731948B1/en active Active
- 2012-07-12 IN IN258MUN2014 patent/IN2014MN00258A/en unknown
- 2012-07-12 CN CN201280034912.XA patent/CN103874702B/zh not_active Expired - Fee Related
- 2012-07-12 AU AU2012285931A patent/AU2012285931B2/en not_active Ceased
- 2012-07-12 MX MX2014000626A patent/MX2014000626A/es unknown
- 2012-07-12 EA EA201490287A patent/EA023045B1/ru not_active IP Right Cessation
- 2012-07-12 WO PCT/EP2012/063667 patent/WO2013010904A1/en active Application Filing
- 2012-07-12 BR BR112014000713A patent/BR112014000713A2/pt active Search and Examination
- 2012-07-12 ES ES12733754.1T patent/ES2555167T3/es active Active
- 2012-07-12 CA CA2841102A patent/CA2841102C/en not_active Expired - Fee Related
- 2012-07-12 KR KR1020147003465A patent/KR101913135B1/ko active IP Right Grant
- 2012-07-12 TW TW101125035A patent/TWI567079B/zh not_active IP Right Cessation
- 2012-07-12 US US14/233,078 patent/US9115143B2/en not_active Expired - Fee Related
- 2012-07-12 JP JP2014519557A patent/JP6068464B2/ja not_active Expired - Fee Related
- 2012-07-13 AR ARP120102548A patent/AR087182A1/es not_active Application Discontinuation
-
2014
- 2014-01-13 IL IL230422A patent/IL230422B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ES2555167T3 (es) | 2015-12-29 |
| TWI567079B (zh) | 2017-01-21 |
| US9115143B2 (en) | 2015-08-25 |
| IL230422B (en) | 2018-03-29 |
| MX2014000626A (es) | 2014-04-30 |
| TW201315736A (zh) | 2013-04-16 |
| US20140148450A1 (en) | 2014-05-29 |
| JP2014518286A (ja) | 2014-07-28 |
| KR20140063595A (ko) | 2014-05-27 |
| BR112014000713A2 (pt) | 2017-01-10 |
| EA023045B1 (ru) | 2016-04-29 |
| AU2012285931B2 (en) | 2017-01-12 |
| CA2841102A1 (en) | 2013-01-24 |
| NZ619683A (en) | 2015-01-30 |
| WO2013010904A1 (en) | 2013-01-24 |
| JP6068464B2 (ja) | 2017-01-25 |
| CN103874702B (zh) | 2015-12-09 |
| CN103874702A (zh) | 2014-06-18 |
| EP2731948A1 (en) | 2014-05-21 |
| EP2731948B1 (en) | 2015-09-09 |
| CA2841102C (en) | 2019-08-13 |
| KR101913135B1 (ko) | 2018-10-30 |
| AR087182A1 (es) | 2014-02-26 |
| EA201490287A1 (ru) | 2014-05-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IN2014MN00258A (ru) | ||
| MX2012008259A (es) | Novedosos derivados biciclicos de triazol sustituidos como moduladores de gamma secretasa. | |
| MX2011008335A (es) | Novedosos compuestos heterociclicos biciclicos sustituidos como moduladores de la gamma secretasa. | |
| MX2011011753A (es) | Nuevos derivados sustitutos de indazol y aza-indazol como moduladores de la gamma secretasa. | |
| MX2012000763A (es) | Derivados sustituidos de triazol e imidazol como moduladores de la gamma secretasa. | |
| UA104151C2 (ru) | Замещенные бициклические производные имидазола как модуляторы гамма-секретазы | |
| MY151983A (en) | Novel substituted benzoxazole, benzimidazole, oxazolopyridine and imidazopyridine derivatives as gamma secretase modulators | |
| IN2014MN02598A (ru) | ||
| MX2014013957A (es) | Derivados de 3,4-dihidro-2h-pirido[1,2-a]pirazin-1,6-diona sustituidos utiles para el tratamiento de la enfermedad de alzheimer (inter alia). | |
| IN2014CN04530A (ru) | ||
| CA2891755C (en) | Substituted pyrido-piperazinone derivatives as gamma secretase modulators | |
| MY169986A (en) | Benzimidazole-proline derivatives | |
| MX2016006336A (es) | Compuestos pirazolopirimidina. | |
| GEP20146146B (en) | Pyrrolopyrimidine compounds as inhibitors of cdk4/6 | |
| NZ703162A (en) | Heterocyclic modulators of lipid synthesis | |
| PH12014501514A1 (en) | New azetidine derivatives, pharmaceutical compositions and uses thereof | |
| MX367772B (es) | Derivados de n-(2,3-dihidro-1h-pirrolo[2,3,b]piridin-5-il)-4-quina zolinamina y n-(2,3-dihidro-1h-indol-5-il)-4-quinazolinamina novedosos como inhibidores de perk. | |
| MX364610B (es) | Derivados de 1- [m-carboxamido (hetero) aril-metil]-heterociclil-c arboxamida. | |
| MX368635B (es) | Compuestos tricíclicos de piperidina. | |
| MX2013005966A (es) | Nuevos compuestos de benzofurano. | |
| MX2014008918A (es) | Nuevos derivados de pirrolidina. | |
| MX2014009084A (es) | Derivados de pirimidooxazocina como inhibidores de mtor. | |
| GEP20156247B (en) | Novel dihydrobenzoxathiazepine derivatives, preparation thereof, and pharmaceutical compositions containing them | |
| CA2818993A1 (en) | Modulators of s1p receptors | |
| UA108365C2 (ru) | Производные замещенного бициклического триазола как модуляторы гамма-секретазы |