IN2014DN02241A - - Google Patents
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- IN2014DN02241A IN2014DN02241A IN2241DEN2014A IN2014DN02241A IN 2014DN02241 A IN2014DN02241 A IN 2014DN02241A IN 2241DEN2014 A IN2241DEN2014 A IN 2241DEN2014A IN 2014DN02241 A IN2014DN02241 A IN 2014DN02241A
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- Prior art keywords
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- present
- drug
- internal standard
- quantitative analysis
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5038—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving detection of metabolites per se
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00594—Quality control, including calibration or testing of components of the analyser
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
- G16B50/30—Data warehousing; Computing architectures
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0027—Methods for using particle spectrometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Theoretical Computer Science (AREA)
- Biophysics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medical Informatics (AREA)
- Evolutionary Biology (AREA)
- Databases & Information Systems (AREA)
- Bioethics (AREA)
- Toxicology (AREA)
- Quality & Reliability (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69498305P | 2005-06-30 | 2005-06-30 | |
| US69498405P | 2005-06-30 | 2005-06-30 | |
| PCT/EP2006/006328 WO2007003344A2 (en) | 2005-06-30 | 2006-06-29 | Device for quantitative analysis of a metabolite profile |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN02241A true IN2014DN02241A (de) | 2015-07-10 |
Family
ID=36783737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2241DEN2014 IN2014DN02241A (de) | 2005-06-30 | 2006-06-29 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8116983B2 (de) |
| EP (2) | EP1875401B1 (de) |
| JP (2) | JP4829297B2 (de) |
| KR (1) | KR100967573B1 (de) |
| CN (1) | CN100594501C (de) |
| AU (1) | AU2006265381B2 (de) |
| BR (1) | BRPI0613478B8 (de) |
| CA (2) | CA2608965C (de) |
| DK (2) | DK1875401T3 (de) |
| ES (1) | ES2452025T3 (de) |
| IL (1) | IL187470A (de) |
| IN (1) | IN2014DN02241A (de) |
| NO (1) | NO339319B1 (de) |
| NZ (1) | NZ563431A (de) |
| RU (1) | RU2391672C2 (de) |
| WO (2) | WO2007003344A2 (de) |
Families Citing this family (75)
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| ES2297831T3 (es) | 1994-05-09 | 2008-05-01 | Oxford Biomedica (Uk) Limited | Vectores retroviricos que presentan una tasa de recombinacion reducida. |
| US8969089B2 (en) | 2004-10-12 | 2015-03-03 | Quest Diagnostics Investments, Inc. | Analysis of amino acids in body fluid by liquid chromatography-mass spectrometry |
| WO2009006338A1 (en) * | 2007-06-29 | 2009-01-08 | Quest Diagnostics Investments Incorporated | Analysis of amino acids in body fluid by liquid chromatography-mass spectrometry |
| CA2608965C (en) * | 2005-06-30 | 2014-08-19 | Biocrates Life Sciences Ag | Device for quantitative analysis of a metabolite profile |
| CA2651227C (en) * | 2006-05-05 | 2016-03-01 | Perkinelmer Las, Inc. | Quantitative analysis of surface-derived samples using mass spectrometry |
| EP1923806A1 (de) * | 2006-11-14 | 2008-05-21 | Metanomics GmbH | Schnelle, metabolomische Analyse und System dafür |
| US7999084B2 (en) * | 2007-05-16 | 2011-08-16 | Agilent Technologies, Inc. | Devices and methods for reducing matrix effects |
| AU2008256445B2 (en) * | 2007-05-31 | 2015-02-26 | Biocrates Life Sciences Ag | Biomarker and method for determining an oxidative stress level |
| AU2008256444A1 (en) * | 2007-05-31 | 2008-12-04 | Biocrates Life Sciences Ag | Inflammation and oxidative stress level assay |
| US12367163B2 (en) | 2007-06-29 | 2025-07-22 | Quest Diagnostics Investments Llc | Analysis of amino acids in body fluid by liquid chromatography—mass spectrometry |
| JP5306345B2 (ja) * | 2007-07-26 | 2013-10-02 | フェノメノーム ディスカバリーズ インク | 自閉症スペクトラム障害の診断、リスク評価、及びモニタリングを行うための方法 |
| DE102007043614B3 (de) * | 2007-09-13 | 2008-11-20 | Biocrates Life Sciences Gmbh | Halterung für ein Trägermittel zum Einsetzen in eine zylinderförmige Öffnung |
| US20090087913A1 (en) * | 2007-10-01 | 2009-04-02 | Mds Analytical Technologies, A Business Unit Of Mds Inc.,Doing Business Through Its Sciex Division | Analysis of conjugated metabolites of alcohol consumption |
| WO2009070233A1 (en) * | 2007-11-26 | 2009-06-04 | Waters Technologies Corporation | Internal standards and methods for use in quantitatively measuring analytes in a sample |
| WO2009152198A2 (en) * | 2008-06-13 | 2009-12-17 | Smiths Detection-Toronto Ltd. | Analytical instrument |
| CN107254538A (zh) | 2008-11-12 | 2017-10-17 | 卡里斯生命科学瑞士控股有限责任公司 | 使用外来体来确定表现型的方法和系统 |
| WO2011109440A1 (en) | 2010-03-01 | 2011-09-09 | Caris Life Sciences Luxembourg Holdings | Biomarkers for theranostics |
| EP2192196A1 (de) | 2008-11-27 | 2010-06-02 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Vorhersage von physiologischen Suszeptibilitäten im Zusammenhang mit dem Lipid-Metabotyp |
| JP5325973B2 (ja) | 2009-03-05 | 2013-10-23 | 株式会社日立ハイテクノロジーズ | 分析装置 |
| US9500572B2 (en) | 2009-04-30 | 2016-11-22 | Purdue Research Foundation | Sample dispenser including an internal standard and methods of use thereof |
| US8859956B2 (en) * | 2009-04-30 | 2014-10-14 | Purdue Research Foundation | Ion generation using wetted porous material |
| ES2799327T3 (es) | 2009-05-05 | 2020-12-16 | Infandx Ag | Método para diagnosticar asfixia |
| US20120129265A1 (en) * | 2009-06-02 | 2012-05-24 | Biocrates Life Sciences Ag | New biomarkers for assessing kidney diseases |
| CA2782284A1 (en) | 2009-11-30 | 2011-06-03 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Methods and systems for isolating, storing, and analyzing vesicles |
| EP2524059A4 (de) | 2010-01-13 | 2013-11-20 | Caris Life Sciences Luxembourg Holdings | Detektion von gastrointestinalen erkrankungen |
| US9469876B2 (en) | 2010-04-06 | 2016-10-18 | Caris Life Sciences Switzerland Holdings Gmbh | Circulating biomarkers for metastatic prostate cancer |
| US9536720B2 (en) * | 2010-10-29 | 2017-01-03 | Atonarp Inc. | Analyzing apparatus |
| MY166283A (en) | 2010-10-29 | 2018-06-25 | Thermo Fisher Scientific Oy | Automated system for sample preparation and analysis |
| EP2492690A1 (de) * | 2011-02-22 | 2012-08-29 | BIOCRATES Life Sciences AG | Verfahren und Verwendung von Metaboliten zur Diagnose einer entzündlichen Hirnverletzung bei frühgeborenen Kindern |
| EP2587264A1 (de) | 2011-10-25 | 2013-05-01 | InfanDx AG | Verfahren und Verwendung von Metaboliten zur Diagnose und Differenzierung einer Encephalopathie bei Neugeborenen |
| WO2013078222A1 (en) | 2011-11-23 | 2013-05-30 | Quest Diagnostics Investments Incorporated | Kisspeptin-54 detection by tandem mass spectrometry |
| JP6198408B2 (ja) * | 2012-04-02 | 2017-09-20 | 株式会社日立ハイテクノロジーズ | サンプル液に含まれる揮発性物質の分析方法 |
| US8870028B2 (en) | 2012-05-25 | 2014-10-28 | Restek Corporation | Dispensing device |
| WO2014026991A1 (en) * | 2012-08-13 | 2014-02-20 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Biomarkers for type 2 diabetes |
| WO2014072537A1 (de) | 2012-11-12 | 2014-05-15 | Biocrates Life Sciences Ag | Verwendung von qualitätsindikatoren zum nachweis von auftauprozessen in gefrorenen gewebeproben |
| WO2014110196A1 (en) * | 2013-01-10 | 2014-07-17 | Restek Corporation | Dispensing device and method |
| WO2014120552A1 (en) | 2013-01-31 | 2014-08-07 | Purdue Research Foundation | Methods of analyzing crude oil |
| EP3742472A1 (de) | 2013-01-31 | 2020-11-25 | Purdue Research Foundation | Methoden zur analyse einer entnommenen probe |
| US9620344B2 (en) | 2013-06-25 | 2017-04-11 | Purdue Research Foundation | Mass spectrometry analysis of microorganisms in samples |
| CN103558354B (zh) * | 2013-11-15 | 2015-07-15 | 南京大学 | 一种基于生物组学整合技术的水体毒性分析方法 |
| JP2017101924A (ja) * | 2014-03-31 | 2017-06-08 | 積水メディカル株式会社 | 内部標準物質試薬 |
| CN104200087B (zh) * | 2014-06-05 | 2018-10-02 | 清华大学 | 用于机器学习的参数寻优及特征调优的方法及系统 |
| US9786478B2 (en) | 2014-12-05 | 2017-10-10 | Purdue Research Foundation | Zero voltage mass spectrometry probes and systems |
| CN113725063B (zh) | 2015-02-06 | 2024-09-20 | 普度研究基金会 | 探针、盒、系统和样本分析的方法 |
| EP3171173A1 (de) | 2015-11-19 | 2017-05-24 | Medizinische Universität Innsbruck | Methode zur diagnose von aortenaneurysmen im brustkorb |
| EP3397972A2 (de) | 2015-12-31 | 2018-11-07 | Universal Diagnostics, S.L. | Systeme und verfahren für ein automatisiertes personalisierbares probenvorbereitungswerkzeug, softwareskript und kalibrierroutine zur erkennung von metaboliten und lipiden |
| DE102017112612A1 (de) | 2016-06-10 | 2017-12-14 | Hitachi High-Tech Science Corporation | Flüssigkeitschromatograph und Verfahren zum Korrigieren von Schwankungen eines Detektorausgabewerts des Flüssigkeitschromatographen |
| US10607723B2 (en) | 2016-07-05 | 2020-03-31 | University Of Kentucky Research Foundation | Method and system for identification of metabolites using mass spectra |
| WO2018085835A1 (en) | 2016-11-07 | 2018-05-11 | Battelle Memorial Institute | Nanoscale biochemical sample preparation and analysis |
| US11719702B2 (en) * | 2016-11-07 | 2023-08-08 | Battelle Memorial Institute | Methods and systems of proteome analysis and imaging |
| EP3351938A1 (de) * | 2017-01-18 | 2018-07-25 | BIOCRATES Life Sciences AG | Neue biomarker zur beurteilung von eierstockkrebs |
| EP3376230A1 (de) | 2017-03-13 | 2018-09-19 | Biocross, S.L. | Identifizierung von signaturen für neurodegenerationserkrankungsdiagnosen |
| WO2018174876A1 (en) * | 2017-03-22 | 2018-09-27 | Mprobe Inc. | Methods and compositions for providing a preeclampsia assessment with metabolites |
| CN107727850B (zh) * | 2017-10-10 | 2021-08-27 | 常州博闻迪医药股份有限公司 | 一种侧向流层析检测反应启动控制方法 |
| JP6991436B2 (ja) * | 2017-05-17 | 2022-01-12 | ラジオメーター・メディカル・アー・ペー・エス | 流体中の検体を検出するための多孔質光ファイバ |
| CN107561150A (zh) * | 2017-07-03 | 2018-01-09 | 宁波华仪宁创智能科技有限公司 | 吸毒的检测方法 |
| CN107798981A (zh) * | 2017-10-31 | 2018-03-13 | 楚雄医药高等专科学校 | 一种永久性教学用微囊标本片及其制作方法 |
| CN109030673A (zh) * | 2018-07-04 | 2018-12-18 | 易达精准（杭州）科技有限公司 | 干血片中免疫抑制剂的检测方法以及检测试剂盒 |
| CN109298115B (zh) * | 2018-10-19 | 2020-07-28 | 深圳市绘云生物科技有限公司 | 生物样品中多种代谢物定量检测方法及代谢芯片 |
| WO2020099683A1 (en) | 2018-11-16 | 2020-05-22 | Biocrates Life Sciences Ag | Metabolites for use in ovarian cancer detection and diagnosis |
| FR3091351B1 (fr) | 2018-12-27 | 2021-05-21 | Univ Rouen Centre Hospitalier | Biomarqueur de la maladie de fabry |
| KR102035162B1 (ko) * | 2019-03-12 | 2019-11-08 | 한국과학기술원 | 질병 표적 대사 효소에 특이적인 인체 대사 물질을 이용하여 질병에 대한 약물 후보를 예측하는 방법 |
| JP7455864B2 (ja) | 2019-05-20 | 2024-03-26 | バテル エナジー アライアンス，エルエルシー | 緻密なグラファイトを作製するための放電プラズマ焼結方法 |
| GB201916046D0 (en) * | 2019-11-04 | 2019-12-18 | Amazentis Sa | Diagnostic method |
| CN111579665B (zh) * | 2020-05-20 | 2021-11-05 | 苏州帕诺米克生物医药科技有限公司 | 一种基于uplc/hrms的代谢组学相对定量分析方法 |
| US20230204544A1 (en) * | 2020-05-21 | 2023-06-29 | Mayo Foundation For Medical Education And Research | Calibration methods for mass spectrometry measurements |
| CN111704654B (zh) * | 2020-06-18 | 2021-12-03 | 上海交通大学医学院附属仁济医院 | 肽类化合物及其制备方法与应用 |
| EP4419255A4 (de) * | 2021-10-21 | 2025-10-15 | Pinpoint Testing Llc | Nachbereitbare analytische plattformen für chemische analysen und quantifizierung von analyten in biologischen proben |
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| JP7206365B1 (ja) | 2021-12-22 | 2023-01-17 | 浜松ホトニクス株式会社 | 試料支持体 |
| KR102547430B1 (ko) * | 2022-11-16 | 2023-06-23 | (주)애터미오롯 | 노니 함유 조성물의 정성 분석 방법 |
| EP4630813A2 (de) * | 2022-12-05 | 2025-10-15 | Washington University | Verbessertes verfahren für skalierbaren ungerichteten metabolomischen arbeitsablauf |
| GB2636339A (en) | 2023-08-30 | 2025-06-18 | Cambridge Entpr Ltd | Biomarkers for bipolar disorder |
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