BRPI0613478B8 - dispositivo para análise quantitativa de um perfil de metabólito - Google Patents

dispositivo para análise quantitativa de um perfil de metabólito

Info

Publication number
BRPI0613478B8
BRPI0613478B8 BRPI0613478A BRPI0613478A BRPI0613478B8 BR PI0613478 B8 BRPI0613478 B8 BR PI0613478B8 BR PI0613478 A BRPI0613478 A BR PI0613478A BR PI0613478 A BRPI0613478 A BR PI0613478A BR PI0613478 B8 BRPI0613478 B8 BR PI0613478B8
Authority
BR
Brazil
Prior art keywords
metabolite profile
quantitative analysis
relates
present
drug
Prior art date
Application number
BRPI0613478A
Other languages
English (en)
Inventor
Armin Graber
Wolfgang Guggenbichler
Steven Lewis Ramsay
Wolfgang Markus STÖGGL
Klaus Michael Weinberger
Original Assignee
Biocrates Life Sciences Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocrates Life Sciences Ag filed Critical Biocrates Life Sciences Ag
Publication of BRPI0613478A2 publication Critical patent/BRPI0613478A2/pt
Publication of BRPI0613478B1 publication Critical patent/BRPI0613478B1/pt
Publication of BRPI0613478B8 publication Critical patent/BRPI0613478B8/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5038—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving detection of metabolites per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/30—Data warehousing; Computing architectures
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Evolutionary Biology (AREA)
  • Databases & Information Systems (AREA)
  • Medical Informatics (AREA)
  • Bioethics (AREA)
  • Toxicology (AREA)
  • Quality & Reliability (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)

Abstract

dispositivo para análise quantitativa de um perfil de metabólito a presente invenção se refere a um dispositivo, em particular a um dispositivo de preparação de amostra para a análise quantitativa de um perfil de droga e/ou de metabólito em uma amostra biológica. além do mais, a presente invenção se refere a uma inserção para um tal dispositivo, a referida inserção sendo impregnada com pelo menos um padrão interno, ao padrão interno em si mesmo, e a um kit compreendendo o dispositivo. adicionalmente, a presente invenção também se refere a um aparelho contendo o dispositivo, e a um método para a análise quantitativa de um perfil de droga e/ou de metabólito em uma amostra biológica empregando o referido dispositivo.
BRPI0613478A 2005-06-30 2006-06-29 dispositivo para análise quantitativa de um perfil de metabólito BRPI0613478B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US69498405P 2005-06-30 2005-06-30
US69498305P 2005-06-30 2005-06-30
US60/694,984 2005-06-30
US60/694,983 2005-06-30
PCT/EP2006/006328 WO2007003344A2 (en) 2005-06-30 2006-06-29 Device for quantitative analysis of a metabolite profile

Publications (3)

Publication Number Publication Date
BRPI0613478A2 BRPI0613478A2 (pt) 2012-01-17
BRPI0613478B1 BRPI0613478B1 (pt) 2019-07-09
BRPI0613478B8 true BRPI0613478B8 (pt) 2021-07-27

Family

ID=36783737

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0613478A BRPI0613478B8 (pt) 2005-06-30 2006-06-29 dispositivo para análise quantitativa de um perfil de metabólito

Country Status (16)

Country Link
US (2) US8265877B2 (pt)
EP (2) EP1897014B1 (pt)
JP (2) JP4829297B2 (pt)
KR (1) KR100967573B1 (pt)
CN (1) CN100594501C (pt)
AU (1) AU2006265381B2 (pt)
BR (1) BRPI0613478B8 (pt)
CA (2) CA2608965C (pt)
DK (2) DK1897014T3 (pt)
ES (1) ES2452025T3 (pt)
IL (1) IL187470A (pt)
IN (1) IN2014DN02241A (pt)
NO (1) NO339319B1 (pt)
NZ (1) NZ563431A (pt)
RU (1) RU2391672C2 (pt)
WO (2) WO2007003343A1 (pt)

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US20070004044A1 (en) 2007-01-04
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CA2608963A1 (en) 2007-01-11
EP1897014B1 (en) 2014-01-15
RU2008102835A (ru) 2009-08-10
KR20080025092A (ko) 2008-03-19
IL187470A (en) 2015-02-26
DK1897014T3 (en) 2014-03-10
US20070003965A1 (en) 2007-01-04
ES2452025T3 (es) 2014-03-31
IL187470A0 (en) 2008-03-20
CN100594501C (zh) 2010-03-17
EP1875401A2 (en) 2008-01-09
BRPI0613478B1 (pt) 2019-07-09
NO339319B1 (no) 2016-11-28
BRPI0613478A2 (pt) 2012-01-17
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CN101208697A (zh) 2008-06-25
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AU2006265381B2 (en) 2010-06-10
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