IN2014CN02448A - - Google Patents
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- Publication number
- IN2014CN02448A IN2014CN02448A IN2448CHN2014A IN2014CN02448A IN 2014CN02448 A IN2014CN02448 A IN 2014CN02448A IN 2448CHN2014 A IN2448CHN2014 A IN 2448CHN2014A IN 2014CN02448 A IN2014CN02448 A IN 2014CN02448A
- Authority
- IN
- India
- Prior art keywords
- glucagon peptides
- obesity
- treatment
- present
- peptides
- Prior art date
Links
- 102000051325 Glucagon Human genes 0.000 abstract 5
- 108060003199 Glucagon Proteins 0.000 abstract 5
- 208000008589 Obesity Diseases 0.000 abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 abstract 2
- 201000001421 hyperglycemia Diseases 0.000 abstract 2
- 235000020824 obesity Nutrition 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11182476 | 2011-09-23 | ||
| US201161539148P | 2011-09-26 | 2011-09-26 | |
| PCT/EP2012/068649 WO2013041678A1 (en) | 2011-09-23 | 2012-09-21 | Novel glucagon analogues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN02448A true IN2014CN02448A (enExample) | 2015-06-19 |
Family
ID=47911932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2448CHN2014 IN2014CN02448A (enExample) | 2011-09-23 | 2012-09-21 |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US8541368B2 (enExample) |
| EP (1) | EP2758426B1 (enExample) |
| JP (2) | JP6352806B2 (enExample) |
| KR (1) | KR20140070612A (enExample) |
| CN (1) | CN104093735B (enExample) |
| AR (1) | AR088161A1 (enExample) |
| AU (1) | AU2012311484B2 (enExample) |
| BR (1) | BR112014006684A2 (enExample) |
| CA (1) | CA2849673A1 (enExample) |
| IL (1) | IL231199A0 (enExample) |
| IN (1) | IN2014CN02448A (enExample) |
| MX (1) | MX354705B (enExample) |
| MY (1) | MY167234A (enExample) |
| RU (2) | RU2610175C2 (enExample) |
| TW (1) | TWI596110B (enExample) |
| WO (1) | WO2013041678A1 (enExample) |
| ZA (1) | ZA201401603B (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2572770A1 (en) * | 2004-07-08 | 2006-01-19 | Novo-Nordisk A/S | Polypeptide protracting tags comprising a tetrazole moiety |
| AP3329A (en) | 2009-07-13 | 2015-06-30 | Zealand Pharma As | Acylated glucagon analogues |
| MY167234A (en) | 2011-09-23 | 2018-08-14 | Novo Nordisk As | Novel glucagon analogues |
| WO2013164483A1 (en) | 2012-05-03 | 2013-11-07 | Zealand Pharma A/S | Gip-glp-1 dual agonist compounds and methods |
| IN2015DN00544A (enExample) | 2012-07-23 | 2015-06-26 | Zealand Pharma As | |
| TWI608013B (zh) | 2012-09-17 | 2017-12-11 | 西蘭製藥公司 | 升糖素類似物 |
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| SG11201503526UA (en) | 2012-12-21 | 2015-06-29 | Sanofi Sa | Dual glp1/gip or trigonal glp1/gip/glucagon agonists |
| PT2986313T (pt) * | 2013-04-18 | 2019-09-10 | Novo Nordisk As | Co agonistas do recetor de glp-1/glucagon estáveis e prolongados para uso médico |
| WO2014170496A1 (en) * | 2013-04-18 | 2014-10-23 | Novo Nordisk A/S | Stable, protracted glp-1/glucagon receptor co-agonists for medical use |
| CN105377306B (zh) | 2013-06-20 | 2020-03-17 | 诺和诺德股份有限公司 | Glp-1衍生物和其用途 |
| US9988429B2 (en) | 2013-10-17 | 2018-06-05 | Zealand Pharma A/S | Glucagon analogues |
| ES2688708T3 (es) | 2013-10-17 | 2018-11-06 | Zealand Pharma A/S | Análogos de glucagón acilados |
| EP3065767B1 (en) | 2013-11-06 | 2020-12-30 | Zealand Pharma A/S | Gip-glp-1 dual agonist compounds and methods |
| US10131702B2 (en) | 2013-11-06 | 2018-11-20 | Zealand Pharma A/S | Glucagon-GLP-1-GIP triple agonist compounds |
| WO2015086730A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Non-acylated exendin-4 peptide analogues |
| EP3080150B1 (en) | 2013-12-13 | 2018-08-01 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
| WO2015086729A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/gip receptor agonists |
| WO2015086733A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/glucagon receptor agonists |
| MX2016010599A (es) * | 2014-02-18 | 2016-11-18 | Novo Nordisk As | Analogos de glucagon estables y uso para el tratamiento de hipoglucemia. |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自exendin-4之雙重glp-1/升糖素受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物 |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑 |
| WO2015185640A1 (en) * | 2014-06-04 | 2015-12-10 | Novo Nordisk A/S | Glp-1/glucagon receptor co-agonists for medical use |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| CN104926934B (zh) | 2014-09-23 | 2016-11-09 | 蒋先兴 | 胃泌酸调节素类似物 |
| JP2017536343A (ja) * | 2014-10-10 | 2017-12-07 | ノヴォ ノルディスク アー/エス | 安定したglp−1ベースのglp−1/グルカゴン受容体コアゴニスト |
| US10253078B2 (en) | 2014-10-29 | 2019-04-09 | Zealand Pharma A/S | GIP agonist compounds and methods |
| JP6730278B2 (ja) | 2014-11-27 | 2020-07-29 | ノヴォ ノルディスク アー/エス | Glp−1誘導体及びその使用 |
| US10392428B2 (en) | 2014-12-17 | 2019-08-27 | Novo Nordisk A/S | GLP-1 derivatives and uses thereof |
| JOP20200119A1 (ar) * | 2015-01-09 | 2017-06-16 | Lilly Co Eli | مركبات مساعد مشترك من gip وglp-1 |
| PL3283507T3 (pl) | 2015-04-16 | 2020-05-18 | Zealand Pharma A/S | Acylowany analog glukagonu |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| TW201706291A (zh) | 2015-07-10 | 2017-02-16 | 賽諾菲公司 | 作為選擇性肽雙重glp-1/升糖素受體促效劑之新毒蜥外泌肽(exendin-4)衍生物 |
| EP3324997B1 (en) * | 2015-07-22 | 2025-10-01 | Purdue Research Foundation | Modified glucagon molecules |
| TWI622596B (zh) | 2015-10-26 | 2018-05-01 | 美國禮來大藥廠 | 升糖素受體促效劑 |
| EP3402811B1 (en) * | 2016-01-13 | 2022-03-30 | Novo Nordisk A/S | Egf(a) analogues with fatty acid substituents |
| SG11202000135PA (en) | 2017-07-13 | 2020-02-27 | Fuji Oil Holdings Inc | Peptide |
| AU2018303625A1 (en) | 2017-07-19 | 2020-02-06 | Novo Nordisk A/S | Bifunctional compounds |
| US11357861B2 (en) | 2017-09-29 | 2022-06-14 | Hanmi Pharm. Co., Ltd | Protein complex comprising non-peptidyl polymer-coupled fatty acid derivative compound as linker and preparation method therefor |
| JOP20190150A1 (ar) | 2018-06-21 | 2019-12-21 | Merck Sharp & Dohme | مركبات مناهضة لـ pcsk9 |
| EP3921336B1 (en) * | 2019-02-05 | 2023-03-01 | Eli Lilly And Company | Glucagon analog agonists and methods of using the same |
| US20230144324A1 (en) * | 2019-12-20 | 2023-05-11 | Merck Sharp & Dohme Llc | Pcsk9 antagonist compounds |
| TW202440619A (zh) * | 2020-12-18 | 2024-10-16 | 丹麥商諾佛 儂迪克股份有限公司 | Glp-1及澱粉素受體之共促效劑 |
| KR20240118914A (ko) | 2021-01-20 | 2024-08-05 | 바이킹 테라퓨틱스 인코포레이티드 | 대사 및 간 질환 치료를 위한 조성물 및 방법 |
| KR102873595B1 (ko) | 2021-09-15 | 2025-10-22 | 바이킹 테라퓨틱스 인코포레이티드 | 대사 및 간 장애의 치료를 위한 조성물 및 방법 |
| CN113759048B (zh) * | 2021-10-14 | 2022-06-21 | 成都普康唯新生物科技有限公司 | 一种十八烷二酸单叔丁酯检验方法 |
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-
2012
- 2012-09-21 MY MYPI2014000627A patent/MY167234A/en unknown
- 2012-09-21 WO PCT/EP2012/068649 patent/WO2013041678A1/en not_active Ceased
- 2012-09-21 TW TW101134663A patent/TWI596110B/zh not_active IP Right Cessation
- 2012-09-21 AR ARP120103494A patent/AR088161A1/es unknown
- 2012-09-21 IN IN2448CHN2014 patent/IN2014CN02448A/en unknown
- 2012-09-21 EP EP12759773.0A patent/EP2758426B1/en active Active
- 2012-09-21 CN CN201280057736.1A patent/CN104093735B/zh not_active Expired - Fee Related
- 2012-09-21 RU RU2014114434A patent/RU2610175C2/ru not_active IP Right Cessation
- 2012-09-21 JP JP2014531245A patent/JP6352806B2/ja not_active Expired - Fee Related
- 2012-09-21 CA CA2849673A patent/CA2849673A1/en not_active Withdrawn
- 2012-09-21 RU RU2017101333A patent/RU2017101333A/ru unknown
- 2012-09-21 AU AU2012311484A patent/AU2012311484B2/en not_active Ceased
- 2012-09-21 US US13/624,387 patent/US8541368B2/en active Active
- 2012-09-21 MX MX2014003312A patent/MX354705B/es active IP Right Grant
- 2012-09-21 KR KR1020147010449A patent/KR20140070612A/ko not_active Withdrawn
- 2012-09-21 BR BR112014006684A patent/BR112014006684A2/pt not_active Application Discontinuation
-
2013
- 2013-07-09 US US13/937,674 patent/US9486505B2/en active Active
-
2014
- 2014-02-27 IL IL231199A patent/IL231199A0/en unknown
- 2014-03-03 ZA ZA2014/01603A patent/ZA201401603B/en unknown
-
2015
- 2015-02-24 US US14/629,682 patent/US9486506B2/en active Active
-
2016
- 2016-08-16 US US15/237,958 patent/US20160347812A1/en not_active Abandoned
-
2017
- 2017-11-06 JP JP2017213869A patent/JP2018021081A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013041678A1 (en) | 2013-03-28 |
| RU2017101333A (ru) | 2018-12-19 |
| US20130288958A1 (en) | 2013-10-31 |
| MX2014003312A (es) | 2014-04-25 |
| US9486506B2 (en) | 2016-11-08 |
| KR20140070612A (ko) | 2014-06-10 |
| IL231199A0 (en) | 2014-04-30 |
| US9486505B2 (en) | 2016-11-08 |
| US20160347812A1 (en) | 2016-12-01 |
| JP2014527975A (ja) | 2014-10-23 |
| CA2849673A1 (en) | 2013-03-28 |
| TWI596110B (zh) | 2017-08-21 |
| JP6352806B2 (ja) | 2018-07-04 |
| CN104093735B (zh) | 2018-07-06 |
| US8541368B2 (en) | 2013-09-24 |
| MY167234A (en) | 2018-08-14 |
| TW201329102A (zh) | 2013-07-16 |
| CN104093735A (zh) | 2014-10-08 |
| MX354705B (es) | 2018-03-16 |
| BR112014006684A2 (pt) | 2017-03-28 |
| EP2758426A1 (en) | 2014-07-30 |
| EP2758426B1 (en) | 2019-08-07 |
| RU2014114434A (ru) | 2015-10-27 |
| US20150182594A1 (en) | 2015-07-02 |
| AU2012311484A1 (en) | 2014-03-06 |
| RU2610175C2 (ru) | 2017-02-08 |
| US20130079278A1 (en) | 2013-03-28 |
| AR088161A1 (es) | 2014-05-14 |
| ZA201401603B (en) | 2015-02-25 |
| AU2012311484B2 (en) | 2017-04-13 |
| JP2018021081A (ja) | 2018-02-08 |
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