MD4537B1 - Soluţie suprasaturată injectabilă de acetaminofen pentru administrare spinală - Google Patents
Soluţie suprasaturată injectabilă de acetaminofen pentru administrare spinalăInfo
- Publication number
- MD4537B1 MD4537B1 MDA20140138A MD20140138A MD4537B1 MD 4537 B1 MD4537 B1 MD 4537B1 MD A20140138 A MDA20140138 A MD A20140138A MD 20140138 A MD20140138 A MD 20140138A MD 4537 B1 MD4537 B1 MD 4537B1
- Authority
- MD
- Moldova
- Prior art keywords
- spinal administration
- acetaminophen solution
- injectable
- solution
- supersaturated acetaminophen
- Prior art date
Links
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical class CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 title abstract 7
- 229960005489 paracetamol Drugs 0.000 abstract 3
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 230000003444 anaesthetic effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940102223 injectable solution Drugs 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0085—Brain, e.g. brain implants; Spinal cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Invenţia se referă la medicină, în special la farmacologie.Soluţia apoasă injectabilă de acetaminofen pentru utilizare în tratamentul sau în prevenirea durerii prin administrare spinală, în care soluţia injectabilă de acetaminofen este suprasaturată. În unele exemple de realizare soluţia apoasă injectabilă de acetaminofen se administrează simultan, separat sau succesiv cu un anestezic local prin administrare spinală.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT001154A ITMI20121154A1 (it) | 2012-06-29 | 2012-06-29 | Soluzione iniettabile di acetaminofene per la somministrazione spinale |
PCT/IB2013/055277 WO2014002042A1 (en) | 2012-06-29 | 2013-06-27 | Injectable supersaturated acetaminophen solution for spinal administration |
Publications (3)
Publication Number | Publication Date |
---|---|
MD20140138A2 MD20140138A2 (ro) | 2015-06-30 |
MD4537B1 true MD4537B1 (ro) | 2017-12-31 |
MD4537C1 MD4537C1 (ro) | 2018-07-31 |
Family
ID=46690603
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MDA20140138A MD4537C1 (ro) | 2012-06-29 | 2013-06-27 | Soluţie suprasaturată injectabilă de acetaminofen pentru administrare spinală |
Country Status (44)
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA200501302A1 (ru) * | 2003-02-14 | 2006-04-28 | Чо Нгуен-Хуан | Инъецируемый жидкий состав парацетамола |
EP1752139A1 (de) * | 2005-08-05 | 2007-02-14 | TheraSelect GmbH | Stabile, flüssige Formulierung von Paracetamol |
CN101015542A (zh) * | 2007-02-13 | 2007-08-15 | 天津生机集团有限公司 | 家畜用复方对乙酰氨基酚注射液及其制备方法 |
MD3528F1 (ro) * | 2007-09-28 | 2008-03-31 | Serghei Sandru | Metoda de anestezie spinala continua la pacientii in etate |
RU2009105480A (ru) * | 2006-07-18 | 2010-08-27 | Хенфарма Лабораторио С.Л. (Es) | Инъекцируемая жидкая композиция парацетамола |
WO2012001494A2 (en) * | 2010-06-30 | 2012-01-05 | Troikaa Pharmaceuticals Limited | Pharmaceutical compositions comprising paracetamol and process for preparing the same |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994023816A1 (en) * | 1993-04-14 | 1994-10-27 | Nippon Sanso Corporation | Dissolved oxygen reducing apparatus |
US6171298B1 (en) * | 1996-05-03 | 2001-01-09 | Situs Corporation | Intravesical infuser |
FR2751875B1 (fr) | 1996-08-05 | 1998-12-24 | Scr Newpharm | Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation |
FR2809619B1 (fr) | 2000-06-06 | 2004-09-24 | Pharmatop | Nouvelles formulations aqueuses de principes actifs sensibles a l'oxydation et leur procede d'obtention |
DE10112325A1 (de) * | 2001-03-13 | 2002-10-02 | Fresenius Kabi De Gmbh | Lagerstabile Fertiginfusionslösungen des Paracetamols |
HUP0402549A3 (en) * | 2001-12-18 | 2006-01-30 | Tseti Ioulia | Parenteral composition of paracetamol |
US9399012B2 (en) * | 2007-11-13 | 2016-07-26 | Mallinckrodt Ip | Reduced dose intravenous acetaminophen |
EP2307056B1 (en) | 2008-01-17 | 2021-12-15 | Pharmis Biofarmacêutica, LDA | Stabilized aqueous formulation containing paracetamol |
WO2009143558A1 (en) | 2008-05-26 | 2009-12-03 | Silphion Pty Limited | Injectable formulations |
EP2243477A1 (de) | 2009-04-22 | 2010-10-27 | Fresenius Kabi Deutschland GmbH | Paracetamol zur parenteralen Verabreichung |
JP2013006770A (ja) * | 2009-10-09 | 2013-01-10 | Ssp Co Ltd | アセトアミノフェン含有経口液剤 |
-
2012
- 2012-06-29 IT IT001154A patent/ITMI20121154A1/it unknown
-
2013
- 2013-06-27 EA EA201500065A patent/EA028909B1/ru unknown
- 2013-06-27 US US14/411,532 patent/US11344517B2/en active Active
- 2013-06-27 ME MEP-2016-118A patent/ME02431B/me unknown
- 2013-06-27 ES ES13765450.5T patent/ES2578012T3/es active Active
- 2013-06-27 CA CA2876801A patent/CA2876801C/en active Active
- 2013-06-27 JP JP2015519450A patent/JP5876620B2/ja active Active
- 2013-06-27 NZ NZ703829A patent/NZ703829A/en not_active IP Right Cessation
- 2013-06-27 MY MYPI2014703994A patent/MY169251A/en unknown
- 2013-06-27 KR KR1020147036909A patent/KR102118227B1/ko active IP Right Grant
- 2013-06-27 BR BR112014032818-8A patent/BR112014032818B1/pt not_active IP Right Cessation
- 2013-06-27 MX MX2014015402A patent/MX369264B/es active IP Right Grant
- 2013-06-27 WO PCT/IB2013/055277 patent/WO2014002042A1/en active Application Filing
- 2013-06-27 SG SG11201408479WA patent/SG11201408479WA/en unknown
- 2013-06-27 RS RS20160435A patent/RS54844B1/sr unknown
- 2013-06-27 PE PE2014002536A patent/PE20150331A1/es active IP Right Grant
- 2013-06-27 MA MA37811A patent/MA37811B1/fr unknown
- 2013-06-27 MD MDA20140138A patent/MD4537C1/ro not_active IP Right Cessation
- 2013-06-27 AP AP2014008152A patent/AP2014008152A0/xx unknown
- 2013-06-27 PL PL13765450.5T patent/PL2874602T3/pl unknown
- 2013-06-27 DK DK13765450.5T patent/DK2874602T3/en active
- 2013-06-27 SI SI201330208A patent/SI2874602T1/sl unknown
- 2013-06-27 PT PT137654505T patent/PT2874602T/pt unknown
- 2013-06-27 SG SG10201704482YA patent/SG10201704482YA/en unknown
- 2013-06-27 HU HUE13765450A patent/HUE029431T2/en unknown
- 2013-06-27 UA UAA201413899A patent/UA117101C2/uk unknown
- 2013-06-27 CN CN201380034500.0A patent/CN104487051B/zh active Active
- 2013-06-27 GE GEAP201313679A patent/GEP201706689B/en unknown
- 2013-06-27 EP EP13765450.5A patent/EP2874602B1/en active Active
- 2013-06-27 AU AU2013282753A patent/AU2013282753B2/en not_active Ceased
- 2013-06-28 AR ARP130102331 patent/AR091633A1/es unknown
-
2014
- 2014-12-18 TN TN2014000526A patent/TN2014000526A1/fr unknown
- 2014-12-18 NI NI201400147A patent/NI201400147A/es unknown
- 2014-12-22 ZA ZA2014/09478A patent/ZA201409478B/en unknown
- 2014-12-23 IL IL236423A patent/IL236423A/en active IP Right Grant
- 2014-12-26 CL CL2014003536A patent/CL2014003536A1/es unknown
- 2014-12-26 CU CUP2014000150A patent/CU20140150A7/es unknown
- 2014-12-29 DO DO2014000302A patent/DOP2014000302A/es unknown
-
2015
- 2015-01-08 EC ECIEPI2015500A patent/ECSP15000500A/es unknown
- 2015-01-27 CR CR20150036A patent/CR20150036A/es unknown
- 2015-01-27 CO CO15015754A patent/CO7240357A2/es unknown
- 2015-01-27 PH PH12015500178A patent/PH12015500178B1/en unknown
-
2016
- 2016-01-19 US US15/001,064 patent/US20160128955A1/en not_active Abandoned
- 2016-06-20 HR HRP20160706TT patent/HRP20160706T1/hr unknown
- 2016-06-28 CY CY20161100584T patent/CY1117691T1/el unknown
- 2016-07-26 SM SM201600248T patent/SMT201600248B/it unknown
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA200501302A1 (ru) * | 2003-02-14 | 2006-04-28 | Чо Нгуен-Хуан | Инъецируемый жидкий состав парацетамола |
EP1752139A1 (de) * | 2005-08-05 | 2007-02-14 | TheraSelect GmbH | Stabile, flüssige Formulierung von Paracetamol |
RU2009105480A (ru) * | 2006-07-18 | 2010-08-27 | Хенфарма Лабораторио С.Л. (Es) | Инъекцируемая жидкая композиция парацетамола |
CN101015542A (zh) * | 2007-02-13 | 2007-08-15 | 天津生机集团有限公司 | 家畜用复方对乙酰氨基酚注射液及其制备方法 |
MD3528F1 (ro) * | 2007-09-28 | 2008-03-31 | Serghei Sandru | Metoda de anestezie spinala continua la pacientii in etate |
WO2012001494A2 (en) * | 2010-06-30 | 2012-01-05 | Troikaa Pharmaceuticals Limited | Pharmaceutical compositions comprising paracetamol and process for preparing the same |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG4A | Patent for invention issued | ||
KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
MM4A | Patent for invention definitely lapsed due to non-payment of fees |