ECSP15000500A - Solucion de acetaminofen supersaturada inyectable para la administracion por la espina dorsal - Google Patents

Solucion de acetaminofen supersaturada inyectable para la administracion por la espina dorsal

Info

Publication number
ECSP15000500A
ECSP15000500A ECIEPI2015500A ECPI201500500A ECSP15000500A EC SP15000500 A ECSP15000500 A EC SP15000500A EC IEPI2015500 A ECIEPI2015500 A EC IEPI2015500A EC PI201500500 A ECPI201500500 A EC PI201500500A EC SP15000500 A ECSP15000500 A EC SP15000500A
Authority
EC
Ecuador
Prior art keywords
spine
administration
supersaturated
acetaminophen solution
solution injectable
Prior art date
Application number
ECIEPI2015500A
Other languages
English (en)
Inventor
Nicola Caronzolo
Elisabetta Donati
Augusto Mitidieri
Original Assignee
Sintetica S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46690603&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP15000500(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sintetica S A filed Critical Sintetica S A
Publication of ECSP15000500A publication Critical patent/ECSP15000500A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a una solución acuosa inyectable de acetaminofén para uso en el tratamiento o en la prevención de dolor mediante administración por la espina dorsal; en donde la solución inyectable de acetaminofén está supersaturada. En ciertas modalidades, la solución acuosa inyectable de acetaminofén se administra de manera simultánea, separada o en secuencia con un anestésico local mediante administración por la espina dorsal.
ECIEPI2015500A 2012-06-29 2015-01-08 Solucion de acetaminofen supersaturada inyectable para la administracion por la espina dorsal ECSP15000500A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001154A ITMI20121154A1 (it) 2012-06-29 2012-06-29 Soluzione iniettabile di acetaminofene per la somministrazione spinale
PCT/IB2013/055277 WO2014002042A1 (en) 2012-06-29 2013-06-27 Injectable supersaturated acetaminophen solution for spinal administration

Publications (1)

Publication Number Publication Date
ECSP15000500A true ECSP15000500A (es) 2015-11-30

Family

ID=46690603

Family Applications (1)

Application Number Title Priority Date Filing Date
ECIEPI2015500A ECSP15000500A (es) 2012-06-29 2015-01-08 Solucion de acetaminofen supersaturada inyectable para la administracion por la espina dorsal

Country Status (44)

Country Link
US (2) US11344517B2 (es)
EP (1) EP2874602B1 (es)
JP (1) JP5876620B2 (es)
KR (1) KR102118227B1 (es)
CN (1) CN104487051B (es)
AP (1) AP2014008152A0 (es)
AR (1) AR091633A1 (es)
AU (1) AU2013282753B2 (es)
BR (1) BR112014032818B1 (es)
CA (1) CA2876801C (es)
CL (1) CL2014003536A1 (es)
CO (1) CO7240357A2 (es)
CR (1) CR20150036A (es)
CU (1) CU20140150A7 (es)
CY (1) CY1117691T1 (es)
DK (1) DK2874602T3 (es)
DO (1) DOP2014000302A (es)
EA (1) EA028909B1 (es)
EC (1) ECSP15000500A (es)
ES (1) ES2578012T3 (es)
GE (1) GEP201706689B (es)
HR (1) HRP20160706T1 (es)
HU (1) HUE029431T2 (es)
IL (1) IL236423A (es)
IT (1) ITMI20121154A1 (es)
MA (1) MA37811B1 (es)
MD (1) MD4537C1 (es)
ME (1) ME02431B (es)
MX (1) MX369264B (es)
MY (1) MY169251A (es)
NI (1) NI201400147A (es)
NZ (1) NZ703829A (es)
PE (1) PE20150331A1 (es)
PH (1) PH12015500178A1 (es)
PL (1) PL2874602T3 (es)
PT (1) PT2874602T (es)
RS (1) RS54844B1 (es)
SG (2) SG10201704482YA (es)
SI (1) SI2874602T1 (es)
SM (1) SMT201600248B (es)
TN (1) TN2014000526A1 (es)
UA (1) UA117101C2 (es)
WO (1) WO2014002042A1 (es)
ZA (1) ZA201409478B (es)

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0646400B1 (en) * 1993-04-14 2001-07-18 Nippon Sanso Corporation Dissolved oxygen reducing apparatus
US6171298B1 (en) * 1996-05-03 2001-01-09 Situs Corporation Intravesical infuser
FR2751875B1 (fr) 1996-08-05 1998-12-24 Scr Newpharm Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation
FR2809619B1 (fr) 2000-06-06 2004-09-24 Pharmatop Nouvelles formulations aqueuses de principes actifs sensibles a l'oxydation et leur procede d'obtention
DE10112325A1 (de) * 2001-03-13 2002-10-02 Fresenius Kabi De Gmbh Lagerstabile Fertiginfusionslösungen des Paracetamols
US20050203175A1 (en) * 2001-12-18 2005-09-15 Ioulia Tseti Parenteral composition of paracetamol
FR2851164B1 (fr) 2003-02-14 2005-04-22 Xuan Tho Nguyen Formulation liquide injectable de paracetamol
DE102005037653A1 (de) * 2005-08-05 2007-02-15 Theraselect Gmbh Stabile, flüssige Formulierung von Paracetamol
JP4929352B2 (ja) * 2006-07-18 2012-05-09 スペイン ファルマ ソシエダ アノニマ 注入可能なパラセタモール液剤
CN101015542A (zh) * 2007-02-13 2007-08-15 天津生机集团有限公司 家畜用复方对乙酰氨基酚注射液及其制备方法
MD3528G2 (ro) * 2007-09-28 2008-11-30 Сергей ШАНДРУ Metodă de anestezie spinală continuă la pacienţii în etate
WO2009064928A1 (en) * 2007-11-13 2009-05-22 Cadence Pharmaceuticals Reduced dose intravenous acetaminophen
US20110015273A1 (en) 2008-01-17 2011-01-20 Rajnarayana Kandhagatla Stable pharmaceutical aqueous compositions
WO2009143558A1 (en) 2008-05-26 2009-12-03 Silphion Pty Limited Injectable formulations
EP2243477A1 (de) 2009-04-22 2010-10-27 Fresenius Kabi Deutschland GmbH Paracetamol zur parenteralen Verabreichung
JP2013006770A (ja) 2009-10-09 2013-01-10 Ssp Co Ltd アセトアミノフェン含有経口液剤
AU2011273064B2 (en) * 2010-06-30 2014-01-09 Troikaa Pharmaceuticals Limited Pharmaceutical compositions comprising paracetamol and process for preparing the same

Also Published As

Publication number Publication date
MA37811A1 (fr) 2016-10-31
HUE029431T2 (en) 2017-03-28
MD4537B1 (ro) 2017-12-31
UA117101C2 (uk) 2018-06-25
JP2015522004A (ja) 2015-08-03
SG11201408479WA (en) 2015-01-29
CN104487051A (zh) 2015-04-01
EA028909B1 (ru) 2018-01-31
RS54844B1 (sr) 2016-10-31
BR112014032818B1 (pt) 2022-06-14
US11344517B2 (en) 2022-05-31
MY169251A (en) 2019-03-19
NI201400147A (es) 2015-04-13
PH12015500178B1 (en) 2015-04-06
PT2874602T (pt) 2016-07-13
SI2874602T1 (sl) 2016-09-30
AR091633A1 (es) 2015-02-18
HRP20160706T1 (hr) 2016-08-12
SMT201600248B (it) 2016-08-31
AU2013282753B2 (en) 2017-03-02
MD20140138A2 (ro) 2015-06-30
CA2876801A1 (en) 2014-01-03
SG10201704482YA (en) 2017-07-28
WO2014002042A1 (en) 2014-01-03
MX369264B (es) 2019-11-04
BR112014032818A2 (pt) 2017-06-27
EP2874602A1 (en) 2015-05-27
CY1117691T1 (el) 2017-05-17
US20160128955A1 (en) 2016-05-12
CA2876801C (en) 2020-11-03
US20150148379A1 (en) 2015-05-28
ME02431B (me) 2016-09-20
ES2578012T3 (es) 2016-07-20
CL2014003536A1 (es) 2015-05-08
DK2874602T3 (en) 2016-07-04
GEP201706689B (en) 2017-06-26
PE20150331A1 (es) 2015-03-07
PL2874602T3 (pl) 2016-10-31
IL236423A0 (en) 2015-02-26
CR20150036A (es) 2015-03-13
EP2874602B1 (en) 2016-03-30
MD4537C1 (ro) 2018-07-31
CN104487051B (zh) 2017-12-12
DOP2014000302A (es) 2015-03-15
ZA201409478B (en) 2016-01-27
AU2013282753A1 (en) 2015-02-05
KR20150027160A (ko) 2015-03-11
NZ703829A (en) 2016-06-24
AP2014008152A0 (en) 2014-12-31
EA201500065A1 (ru) 2015-10-30
PH12015500178A1 (en) 2015-04-06
CO7240357A2 (es) 2015-04-17
KR102118227B1 (ko) 2020-06-03
MA37811B1 (fr) 2017-07-31
IL236423A (en) 2017-07-31
ITMI20121154A1 (it) 2013-12-30
CU20140150A7 (es) 2015-10-27
JP5876620B2 (ja) 2016-03-02
TN2014000526A1 (en) 2016-03-30
MX2014015402A (es) 2015-06-17

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