EA200501302A1 - Инъецируемый жидкий состав парацетамола - Google Patents

Инъецируемый жидкий состав парацетамола

Info

Publication number
EA200501302A1
EA200501302A1 EA200501302A EA200501302A EA200501302A1 EA 200501302 A1 EA200501302 A1 EA 200501302A1 EA 200501302 A EA200501302 A EA 200501302A EA 200501302 A EA200501302 A EA 200501302A EA 200501302 A1 EA200501302 A1 EA 200501302A1
Authority
EA
Eurasian Patent Office
Prior art keywords
paracetamol
liquid composition
injectable liquid
solution
antipyretic
Prior art date
Application number
EA200501302A
Other languages
English (en)
Other versions
EA008908B1 (ru
Inventor
Чо Нгуен-Хуан
Original Assignee
Чо Нгуен-Хуан
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32749656&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200501302(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Чо Нгуен-Хуан filed Critical Чо Нгуен-Хуан
Publication of EA200501302A1 publication Critical patent/EA200501302A1/ru
Publication of EA008908B1 publication Critical patent/EA008908B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Изобретение относится к новому инъецируемому жидкому составу парацетамола, включающему водный растворитель, буфер с pKa 4,5-6,5, изотонический агент и димер парацетамола формулы (I)к способу получения данного состава и применению димера для стабилизации жидкого фармацевтического состава парацетамола.
EA200501302A 2003-02-14 2004-02-16 Инъецируемый жидкий состав парацетамола EA008908B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0301972A FR2851164B1 (fr) 2003-02-14 2003-02-14 Formulation liquide injectable de paracetamol
PCT/CH2004/000085 WO2004071502A1 (fr) 2003-02-14 2004-02-16 Formulation liquide injectable de paracetamol

Publications (2)

Publication Number Publication Date
EA200501302A1 true EA200501302A1 (ru) 2006-04-28
EA008908B1 EA008908B1 (ru) 2007-08-31

Family

ID=32749656

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200501302A EA008908B1 (ru) 2003-02-14 2004-02-16 Инъецируемый жидкий состав парацетамола

Country Status (13)

Country Link
US (1) US8071619B2 (ru)
EP (1) EP1592414B1 (ru)
JP (1) JP4861162B2 (ru)
CN (1) CN100546574C (ru)
AT (1) ATE464891T1 (ru)
AU (1) AU2004212269B2 (ru)
CA (1) CA2517491C (ru)
DE (1) DE602004026684D1 (ru)
EA (1) EA008908B1 (ru)
ES (1) ES2344697T3 (ru)
FR (1) FR2851164B1 (ru)
MA (1) MA27748A1 (ru)
WO (1) WO2004071502A1 (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4537B1 (ru) * 2012-06-29 2017-12-31 Sintetica S.A. Инъекционный перенасыщенный раствор ацетаминофена для спинального введения

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005037653A1 (de) 2005-08-05 2007-02-15 Theraselect Gmbh Stabile, flüssige Formulierung von Paracetamol
CA2628806C (en) 2006-07-18 2012-08-21 Genfarma Laboratorio S.L. Injectable liquid paracetamol formulation
EP1992334A1 (en) * 2007-05-08 2008-11-19 Docpharma NV/SA Storage-stable formulation of oxidation-sensitive phenolic drug, especially paracetamol, comprises aqueous drug solution deoxygenated by a temperature-controlled manufacturing process of the formulation
EP2170313A2 (en) * 2007-06-18 2010-04-07 Combino Pharm, S.L. Aqueous formulations of acetaminophen for injection
WO2009081283A2 (en) * 2007-06-18 2009-07-02 Combino Pharm, S.L. Aqueous formulations of acetaminophen for injection
WO2009064928A1 (en) 2007-11-13 2009-05-22 Cadence Pharmaceuticals Reduced dose intravenous acetaminophen
WO2009098716A2 (en) * 2008-01-17 2009-08-13 Aptuit Laurus Private Limited Stable pharmaceutical aqueous compositions
FR2926992B1 (fr) * 2008-02-06 2011-01-14 Moly Pharma Formulation d'une solution de paracetamol injectable,procede de preparation et de conditionnement d'une telle solution et dispositif de conditionnement d'une telle solution
ES2321906B1 (es) * 2008-11-28 2010-02-09 Laboratorios Normon, S.A. Composicion farmaceutica que comprende una solucion acuosa de paracetamol.
EP2243477A1 (de) 2009-04-22 2010-10-27 Fresenius Kabi Deutschland GmbH Paracetamol zur parenteralen Verabreichung
US20110207824A1 (en) * 2010-02-25 2011-08-25 Moly Pharma Formulation of an injectable paracetamol solution, method for preparing and packaging such a solution and device for packaging such a solution
ES2389760T3 (es) 2010-04-14 2012-10-31 B. Braun Melsungen Ag Composición de acetaminofeno
PL2389923T3 (pl) * 2010-05-19 2013-06-28 Uni Pharma Kleon Tsetis Pharmaceutical Laboratories S A Trwały, gotowy do użycia iniekcyjny preparat paracetamolu
ES2414557B1 (es) 2012-01-16 2014-06-10 Novocat Farma, S.A. Composición acuosa de paracetamol para inyección
US20140303254A1 (en) * 2013-04-08 2014-10-09 InnoPharma Licensing LLC Process Of Manufacturing A Stable, Ready To Use Infusion Bag For An Oxidation Sensitive Formulation
BR102014005885B1 (pt) 2014-03-13 2021-04-13 Biotec Biológica Indústria Farmacêutica Ltda E.P.P Formulação farmacêutica líquida injetável estável de paracetamol em bolsa plástica pronta para uso
CN108289869B (zh) * 2014-04-28 2021-08-27 奥佛麦德公司 使用通过酚羟基连接的药学活性的对乙酰氨基酚二聚体治疗疼痛的方法
CN110642677B (zh) * 2019-08-30 2023-05-26 浙江工业大学 双芳基衍生物的制备、双芳基衍生物及应用
CN112782332A (zh) * 2021-02-04 2021-05-11 深圳市药品检验研究院（深圳市医疗器械检测中心） 一种对乙酰氨基酚药品中对氨基酚杂质的hplc检测方法
CN114965754B (zh) * 2022-05-13 2024-04-09 陕西必康制药集团控股有限公司 对乙酰氨基酚片中有关物质及抑菌剂的检测方法
CN115385818B (zh) * 2022-09-01 2023-09-29 江苏海洋大学 一种扑热息痛杂质及制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS545022A (en) * 1977-06-14 1979-01-16 Zenyaku Kogyo Kk Production of solution agent containing aqueous licorice extract and acetoaminophenone
JPS61501566A (ja) 1984-03-14 1986-07-31 コルビエ−ル　ジエロ−ム 有効成分の可溶化法およびそれにより得られる薬理組成物
FR2751875B1 (fr) * 1996-08-05 1998-12-24 Scr Newpharm Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation
DK0916347T3 (da) * 1997-11-18 2003-04-22 Uni Pharma Kleon Tsetis A B E Farmaceutiske injicerbare opløsninger der indeholder paracetamol og kombinationer af paracetamol med andre aktive bestanddele
IT1301976B1 (it) * 1998-07-31 2000-07-20 Angelini Ricerche Spa Composizione farmaceutica iniettabile a base di paracetamolo
FR2809619B1 (fr) * 2000-06-06 2004-09-24 Pharmatop Nouvelles formulations aqueuses de principes actifs sensibles a l'oxydation et leur procede d'obtention
DE10112325A1 (de) * 2001-03-13 2002-10-02 Fresenius Kabi De Gmbh Lagerstabile Fertiginfusionslösungen des Paracetamols
ITMI20012135A1 (it) * 2001-10-16 2003-04-16 Bioren S A Soluzioni iniettabili pronte all'uso di paracetamolo

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4537B1 (ru) * 2012-06-29 2017-12-31 Sintetica S.A. Инъекционный перенасыщенный раствор ацетаминофена для спинального введения

Also Published As

Publication number Publication date
JP4861162B2 (ja) 2012-01-25
CN1750818A (zh) 2006-03-22
DE602004026684D1 (de) 2010-06-02
ATE464891T1 (de) 2010-05-15
EP1592414A1 (fr) 2005-11-09
EA008908B1 (ru) 2007-08-31
EP1592414B1 (fr) 2010-04-21
US8071619B2 (en) 2011-12-06
AU2004212269B2 (en) 2009-05-28
CN100546574C (zh) 2009-10-07
FR2851164B1 (fr) 2005-04-22
CA2517491E (fr) 2004-08-26
AU2004212269A1 (en) 2004-08-26
ES2344697T3 (es) 2010-09-03
JP2006517544A (ja) 2006-07-27
WO2004071502A1 (fr) 2004-08-26
CA2517491A1 (fr) 2004-08-26
FR2851164A1 (fr) 2004-08-20
US20060084703A1 (en) 2006-04-20
CA2517491C (fr) 2012-07-31
MA27748A1 (fr) 2006-02-01

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU