IN2012DN06589A - - Google Patents
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- Publication number
- IN2012DN06589A IN2012DN06589A IN6589DEN2012A IN2012DN06589A IN 2012DN06589 A IN2012DN06589 A IN 2012DN06589A IN 6589DEN2012 A IN6589DEN2012 A IN 6589DEN2012A IN 2012DN06589 A IN2012DN06589 A IN 2012DN06589A
- Authority
- IN
- India
- Prior art keywords
- mbl
- sepsis
- infectious diseases
- provides
- bind
- Prior art date
Links
- 102000009112 Mannose-Binding Lectin Human genes 0.000 abstract 3
- 108010087870 Mannose-Binding Lectin Proteins 0.000 abstract 3
- 208000035473 Communicable disease Diseases 0.000 abstract 2
- 206010040047 Sepsis Diseases 0.000 abstract 2
- 244000052769 pathogen Species 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 108010017384 Blood Proteins Proteins 0.000 abstract 1
- 102000004506 Blood Proteins Human genes 0.000 abstract 1
- 208000035049 Blood-Borne Infections Diseases 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- 102000004856 Lectins Human genes 0.000 abstract 1
- 108090001090 Lectins Proteins 0.000 abstract 1
- 108700022034 Opsonin Proteins Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 210000005007 innate immune system Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4726—Lectins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56961—Plant cells or fungi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/66—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a swap of domains, e.g. CH3-CH2, VH-CL or VL-CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
- G01N2333/39—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts
- G01N2333/40—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts from Candida
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
- G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
- G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Mycology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29622210P | 2010-01-19 | 2010-01-19 | |
| PCT/US2011/021603 WO2011090954A2 (en) | 2010-01-19 | 2011-01-19 | Engineered opsonin for pathogen detection and treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN06589A true IN2012DN06589A (en:Method) | 2015-10-23 |
Family
ID=44307537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN6589DEN2012 IN2012DN06589A (en:Method) | 2010-01-19 | 2011-01-19 |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US9150631B2 (en:Method) |
| EP (1) | EP2526119B1 (en:Method) |
| JP (5) | JP5959440B2 (en:Method) |
| CN (1) | CN102947341B (en:Method) |
| AU (1) | AU2011207626B2 (en:Method) |
| CA (1) | CA2787376A1 (en:Method) |
| DK (1) | DK2526119T3 (en:Method) |
| ES (1) | ES2678143T3 (en:Method) |
| IN (1) | IN2012DN06589A (en:Method) |
| SG (2) | SG182577A1 (en:Method) |
| WO (1) | WO2011090954A2 (en:Method) |
Families Citing this family (51)
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|---|---|---|---|---|
| US9220831B2 (en) | 2005-10-06 | 2015-12-29 | Children's Medical Center Corporation | Device and method for combined microfluidic-micromagnetic separation of material in continuous flow |
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| WO2010123594A2 (en) | 2009-01-15 | 2010-10-28 | Children's Medical Center Corporation | Device for filtration of fluids there through and accompanying method |
| IN2012DN06589A (en:Method) | 2010-01-19 | 2015-10-23 | Harvard College | |
| EP3620185A1 (en) | 2010-10-06 | 2020-03-11 | President and Fellows of Harvard College | Injectable, pore-forming hydrogels for materials-based cell therapies |
| GB2502927A (en) * | 2011-03-25 | 2013-12-11 | Receptors Llc | Fiber with microbial removal, micro-biocidal, or static growth capability |
| JP2014514060A (ja) * | 2011-04-01 | 2014-06-19 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 透析様治療(dlt)装置 |
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| CN104284984B (zh) * | 2012-02-29 | 2017-10-13 | 哈佛大学校长及研究员协会 | 抗生素药敏性的快速测试 |
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| EP2976642A4 (en) * | 2013-03-15 | 2016-09-21 | Harvard College | METHOD AND COMPOSITIONS FOR IMPROVING THE DETECTION AND / OR RECORDING OF A TARGET UNIT |
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| WO2019064463A1 (ja) * | 2017-09-28 | 2019-04-04 | 学校法人中部大学 | バイオアフィニティーを利用したウイルス又は細菌の濃縮方法及び装置 |
| KR102084688B1 (ko) * | 2018-06-18 | 2020-03-04 | 울산과학기술원 | 다중 프로브 혼성화를 이용한 미생물 검출 방법 |
| WO2020061129A1 (en) | 2018-09-19 | 2020-03-26 | President And Fellows Of Harvard College | Compositions and methods for labeling and modulation of cells in vitro and in vivo |
| CN110628624B (zh) * | 2019-02-01 | 2022-07-15 | 传鸣(宁波)化学科技有限公司 | 一种磁性微生物捕获材料及微生物捕获方法 |
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| CN111675825B (zh) * | 2020-06-09 | 2022-06-24 | 大连工业大学 | 一种附有胰蛋白酶的微孔膜的制备方法及其在蛋白水解中的应用 |
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| US20240199719A1 (en) | 2020-08-28 | 2024-06-20 | Miraki Innovation Think Tank Llc | Therapeutic compositions comprising microbe-targeting molecules and their use in methods of preventing and treating infectious disease |
| US20240019435A1 (en) | 2020-09-25 | 2024-01-18 | Miraki Innovation Think Tank Llc | Compositions, devices and methods comprising microbe-targeting molecules for diagnosing and treating infectious disease |
| US20230416319A1 (en) | 2020-10-01 | 2023-12-28 | Miraki Innovation Think Tank Llc | Compositions, devices and methods for identifying, treating and preventing infectious disease using microbe-targeting molecules |
| WO2022093935A1 (en) | 2020-10-27 | 2022-05-05 | Miraki Innovation Think Tank Llc | Compositions, systems and methods for pathogen monitoring using microbe-targeting molecules |
| WO2022125632A1 (en) | 2020-12-08 | 2022-06-16 | Miraki Innovation Think Tank Llc | Chimeric antigen receptor-expressing cells targeting microbe-associated molecular patterns |
| WO2022151333A1 (zh) * | 2021-01-15 | 2022-07-21 | 传鸣(宁波)化学科技有限公司 | 用于富集微生物的混合物、方法及应用 |
Family Cites Families (120)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5418198A (en) | 1977-07-09 | 1979-02-09 | Toshimitsu Niwa | Artificial intraretinal device |
| US4425330A (en) | 1981-05-20 | 1984-01-10 | Cornell Research Foundation, Inc. | Bovine mastitis vaccine and method for detecting efficacy thereof |
| WO1984002193A1 (en) | 1982-12-03 | 1984-06-07 | Du Pont | Chromogenic support immunoassay |
| JPS60500548A (ja) | 1982-12-03 | 1985-04-18 | イ−・アイ・デユポン・ド・ネモア−ス・アンド・コンパニ− | 発色性支持体免疫測定法 |
| JPH0718875B2 (ja) | 1987-06-19 | 1995-03-06 | ヤマサ醤油株式会社 | 血中または体液中の微量物質含有量の測定法 |
| JP2868777B2 (ja) | 1987-08-20 | 1999-03-10 | チルドレンズ・ホスピタル・コーポレイション | ヒトマンノース結合タンパク質 |
| US5270199A (en) | 1987-08-20 | 1993-12-14 | The Children's Medical Center Corporation | Human mannose-binding protein |
| ATE122568T1 (de) | 1989-01-25 | 1995-06-15 | Commw Scient Ind Res Org | Polypeptide, antigene oder vakzine gegen babesiosis. |
| US5137810A (en) | 1989-04-26 | 1992-08-11 | The University Of North Carolina | Method of determining the gram sign of bacteria |
| DE4018583A1 (de) | 1990-06-09 | 1991-12-12 | Henkel Kgaa | Modifiziertes verfahren zur direkten herstellung von alkylglykosiden |
| EP0900521A1 (en) | 1990-07-30 | 1999-03-10 | Novartis AG | Insecticidal proteins |
| GB9020075D0 (en) | 1990-09-14 | 1990-10-24 | Filler Aaron G | Contrast agents for magnetic resonance imaging of axonal transport |
| JPH04130274A (ja) | 1990-09-20 | 1992-05-01 | Kyoto Ikagaku Kenkyusho:Kk | 糖蛋白の分析,検出方法 |
| US5783179A (en) | 1991-08-09 | 1998-07-21 | Syntex (U.S.A.) Inc. | C-reactive protein fragment with immunomodulatory activity |
| US5405832A (en) | 1991-11-27 | 1995-04-11 | Immtech International Inc. | Method of treating non-streptococcal bacterial infections |
| US5874238A (en) | 1993-02-26 | 1999-02-23 | Immtech International Inc. | Mutant protein and methods and materials for making and using it |
| JP3457309B2 (ja) | 1991-11-27 | 2003-10-14 | イムテック インターナショナル インコーポレイテッド | ウイルス感染症の治療方法 |
| US5283238A (en) | 1992-04-24 | 1994-02-01 | Immtech International, Inc. | Methods of treating cancer using modified C-reactive protein |
| US6703219B1 (en) | 1993-02-26 | 2004-03-09 | Immtech International Inc. | Mutant protein and methods and materials for making and using it |
| IT1271486B (it) | 1993-10-12 | 1997-05-28 | Italfarmaco Spa | Oligopeptidi immunomodulatori derivati di frammenti della proteina c- reattiva |
| US5541087A (en) | 1994-09-14 | 1996-07-30 | Fuji Immunopharmaceuticals Corporation | Expression and export technology of proteins as immunofusins |
| AUPN214095A0 (en) | 1995-04-03 | 1995-04-27 | Australian Water Technologies Pty Ltd | Method for detecting microorganisms using flow cytometry |
| AU734196B2 (en) | 1996-03-28 | 2001-06-07 | Whitehead Institute | Opsonin-enhanced cells, and methods of modulating an immune response to an antigen |
| ZA973051B (en) | 1996-04-24 | 1998-10-12 | Genentech Inc | Type c lectins |
| US6117977A (en) | 1996-04-24 | 2000-09-12 | Genentech, Inc. | Type C lectins |
| FR2751229B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique notamment contre la pathologie respiratoire des bovins |
| US6294170B1 (en) * | 1997-08-08 | 2001-09-25 | Amgen Inc. | Composition and method for treating inflammatory diseases |
| IL121191A0 (en) | 1997-06-29 | 1997-11-20 | Yeda Res & Dev | Synthetic peptides and pharmaceutical compositions comprising them |
| US7049099B2 (en) | 1998-01-23 | 2006-05-23 | Fuso Pharmaceutical Industries, Ltd. | Recombinant human mannan-binding proteins and producing method of the same |
| JPH11206378A (ja) | 1998-01-23 | 1999-08-03 | Fuso Pharmaceutical Industries Ltd | 組換えヒトマンナン結合タンパク質およびその製造方法 |
| US6528624B1 (en) | 1998-04-02 | 2003-03-04 | Genentech, Inc. | Polypeptide variants |
| JP4707231B2 (ja) | 1998-06-10 | 2011-06-22 | スタテンズ セーラム インスティテュート | マンナン結合レクチンを製造するための精製方法及びmbl医薬品 |
| CA2338989C (en) | 1998-07-31 | 2010-07-27 | Asahi Kasei Kogyo Kabushiki Kaisha | Antibodies for detecting microorganisms |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| DE60033147T2 (de) | 1999-05-14 | 2007-12-13 | Steffen Thiel | Rekombinantes menschliches mannan-bindendes lektin |
| US7754855B1 (en) | 1999-07-13 | 2010-07-13 | Bolder Biotechnology, Inc. | Immunoglobulin fusion proteins |
| US6503761B1 (en) | 1999-10-19 | 2003-01-07 | Kimberly-Clark Worldwide, Inc. | Selective removal of contaminants from a surface using articles having magnets |
| EP1252192B1 (en) * | 2000-02-11 | 2006-08-16 | MERCK PATENT GmbH | Enhancing the circulating half-life of antibody-based fusion proteins |
| US6471968B1 (en) | 2000-05-12 | 2002-10-29 | Regents Of The University Of Michigan | Multifunctional nanodevice platform |
| JP2002165591A (ja) | 2000-09-25 | 2002-06-11 | Jsr Corp | 磁性粒子およびその使用方法 |
| AU2002227184A1 (en) | 2000-10-18 | 2002-04-29 | The Board Of Trustess Of The Leland Stanford Junior University | Methods for development and use of diagnostic and therapeutic agents |
| GB0119274D0 (en) | 2001-08-08 | 2001-10-03 | Univ Durham | Fusion proteins for insect control |
| US6900292B2 (en) * | 2001-08-17 | 2005-05-31 | Lee-Hwei K. Sun | Fc fusion proteins of human erythropoietin with increased biological activities |
| US7396662B2 (en) * | 2001-12-19 | 2008-07-08 | Immunex Corporation | C-type lectin polypeptides |
| US6844426B2 (en) | 2002-02-06 | 2005-01-18 | Toyo Boseki Kabushiki Kaisha | Magnetic carrier capable of binding with protein and purification method of protein utilizing the magnetic carrier |
| JP4959110B2 (ja) | 2002-02-07 | 2012-06-20 | マサチューセッツ インスティテュート オブ テクノロジー | 抗病原体治療 |
| DK1344533T3 (da) | 2002-03-15 | 2007-01-08 | Natimmune As | Farmaceutiske præparater, der omfatter mannosebindende lectin |
| US20030180814A1 (en) | 2002-03-21 | 2003-09-25 | Alastair Hodges | Direct immunosensor assay |
| US7211396B2 (en) | 2002-04-18 | 2007-05-01 | Antibodyshop A/S | Antibody pairs and kits for immunochemical determination of mannan-binding lectin |
| CN1646152A (zh) | 2002-04-24 | 2005-07-27 | 昆士兰医学研究学院理事会 | 甘露糖结合凝集素及其应用 |
| US20040018611A1 (en) | 2002-07-23 | 2004-01-29 | Ward Michael Dennis | Microfluidic devices for high gradient magnetic separation |
| US7629440B2 (en) | 2002-08-20 | 2009-12-08 | Genitrix, Llc | Lectin compositions and methods for modulating an immune response to an antigen |
| BR0313650A (pt) | 2002-08-20 | 2007-08-14 | Genitrix Llc | composição, vetor de expressão, composição de vacina e uso |
| US20060188963A1 (en) | 2002-09-10 | 2006-08-24 | Natlmmune A/S | Collectin-complement activating protein chimeras |
| GB2393728A (en) | 2002-10-04 | 2004-04-07 | Nanomagnetics Ltd | Magnetic nanoparticles |
| EP1417965A1 (en) | 2002-11-07 | 2004-05-12 | Vereniging Voor Christelijk Wetenschappelijk Onderwijs | C-type lectin binding molecules, identification and uses thereof |
| CN101124315A (zh) | 2003-01-17 | 2008-02-13 | 伊势龙医学股份有限公司 | 利用凝集素亲和性血液透析去除血液中病毒的方法 |
| US20050014932A1 (en) | 2003-05-15 | 2005-01-20 | Iogenetics, Llc | Targeted biocides |
| DE10325752A1 (de) | 2003-06-06 | 2004-12-30 | Faustus Forschungs Cie. Translational Cancer Research Gmbh | Lektin-Konjugate |
| WO2005040194A2 (en) | 2003-10-24 | 2005-05-06 | Ludwig Institute For Cancer Research | Methods and compositions for pdgf-c activation and inhibition |
| RU2370276C2 (ru) * | 2003-12-31 | 2009-10-20 | Мерк Патент Гмбх | Fc-ЭРИТРОПОЭТИН СЛИТЫЙ БЕЛОК С УЛУЧШЕННОЙ ФАРМАКОКИНЕТИКОЙ |
| CA2561264A1 (en) | 2004-03-24 | 2005-10-06 | Xencor, Inc. | Immunoglobulin variants outside the fc region |
| SE0401033D0 (sv) | 2004-04-20 | 2004-04-20 | Amersham Biosciences Ab | Device and method for protein analysis |
| WO2007001332A2 (en) | 2004-08-04 | 2007-01-04 | University Of Massachusetts | Anti-pathogen immunoadhesins |
| WO2006018428A2 (en) | 2004-08-20 | 2006-02-23 | Novo Nordisk A/S | Hemopexin fusion proteins |
| ATE536552T1 (de) | 2004-10-15 | 2011-12-15 | Danisco Us Inc | Kompetitven differential screening |
| ES2360504T3 (es) | 2004-10-28 | 2011-06-06 | Dobeel Co., Ltd. | Método para la producción en masa de lectina multimérica de unión a manosa. |
| US20060141547A1 (en) | 2004-11-16 | 2006-06-29 | Das Hasi R | Novel diagnostic marker, a diagnostic kit and a method for diagnosis of rheumatoid arthritis |
| US7172906B2 (en) | 2004-11-16 | 2007-02-06 | Dade Behring Inc. | Reduction of non-specific binding in assays |
| US8084275B2 (en) | 2005-02-08 | 2011-12-27 | Fujifilm Corporation | Magnetic composite body, production method thereof, method for removing substance with mannose on its surface, and method for concentrating substance with mannose on its surface |
| AU2006232310B9 (en) * | 2005-04-06 | 2011-07-21 | Ibc Pharmaceuticals, Inc. | Improved stably tethered structures of defined compositions with multiple functions or binding specificities |
| JP2008535872A (ja) | 2005-04-11 | 2008-09-04 | ナットイムネ・アクティーゼルスカブ | 免疫障害を持つ個体の処置におけるマンナン結合レクチン(mbl)の新規癌適用 |
| US20070031819A1 (en) | 2005-04-26 | 2007-02-08 | University Of Washington | Microfluidic systems for biological and molecular analysis and methods thereof |
| MX2007013914A (es) | 2005-05-09 | 2008-02-22 | Biosphere Medical S A | Composiciones y metodos que usan microesferas y agentes de contraste no ionicos. |
| US20070231833A1 (en) | 2005-05-23 | 2007-10-04 | Arcidiacono Steven M | Labeled antimicrobial peptides and method of using the same to detect microorganisms of interest |
| JP4423394B2 (ja) * | 2005-06-17 | 2010-03-03 | 独立行政法人産業技術総合研究所 | 新規糖鎖認識蛋白質及びその遺伝子 |
| TWI333959B (en) | 2005-08-31 | 2010-12-01 | Academia Sinica | Methods and reagents for the analysis and purification of polysaccharides |
| JP2009509549A (ja) | 2005-09-30 | 2009-03-12 | カリパー・ライフ・サイエンシズ・インク. | 磁気ビーズを用いて生体成分を精製するためのマイクロ流体デバイス |
| US9220831B2 (en) | 2005-10-06 | 2015-12-29 | Children's Medical Center Corporation | Device and method for combined microfluidic-micromagnetic separation of material in continuous flow |
| EP2388013A3 (en) | 2005-10-26 | 2012-03-07 | Science & Technology Corporation @ UNM | C-reactive protein and its use to treat systemic Lupus erythematosus and related conditions |
| US20070269818A1 (en) | 2005-12-28 | 2007-11-22 | Affymetrix, Inc. | Carbohydrate arrays |
| US20090181041A1 (en) | 2006-01-23 | 2009-07-16 | Jan Holgersson | Production of proteins carrying oligomannose or human-like glycans in yeast and methods of use thereof |
| CA2641271A1 (en) | 2006-02-03 | 2008-03-13 | Microchip Biotechnologies, Inc. | Microfluidic devices |
| US8821851B2 (en) | 2006-03-23 | 2014-09-02 | The General Hospital Corporation | Inflammation-inhibitory serum factors and uses thereof |
| WO2007111496A1 (en) * | 2006-03-28 | 2007-10-04 | Universiteit Utrecht Holding B.V. | Improved carbohydrate recognition domains |
| EP1862541A1 (en) | 2006-06-01 | 2007-12-05 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Polypeptides derived from the hemopexin-like domain of metalloproteinase MMP-2 |
| KR101343034B1 (ko) | 2006-09-05 | 2013-12-18 | 삼성전자 주식회사 | 원심력 기반의 단백질 검출용 미세유동 장치 및 이를포함하는 미세유동 시스템 |
| US8273310B2 (en) | 2006-09-05 | 2012-09-25 | Samsung Electronics Co., Ltd. | Centrifugal force-based microfluidic device for nucleic acid extraction and microfluidic system including the microfluidic device |
| US8088596B2 (en) * | 2006-10-10 | 2012-01-03 | Oakland University | Method of microorganism detection using carbohydrate and lectin recognition |
| US8551333B2 (en) | 2007-04-05 | 2013-10-08 | The Regents Of The University Of California | Particle-based microfluidic device for providing high magnetic field gradients |
| US20080260738A1 (en) | 2007-04-18 | 2008-10-23 | Moore Margaret D | Single chain fc, methods of making and methods of treatment |
| WO2008130618A1 (en) | 2007-04-19 | 2008-10-30 | The Charles Stark Draper Laboratory, Inc. | Method and apparatus for separating particles, cells, molecules and particulates |
| AU2008254951A1 (en) | 2007-05-14 | 2008-11-27 | Biogen Idec Ma Inc. | Single-chain Fc (ScFc) regions, binding polypeptides comprising same, and methods related thereto |
| CN105131127B (zh) | 2007-05-30 | 2018-09-07 | 浦项工科大学校产学协力团 | 免疫球蛋白融合蛋白 |
| RU2010113963A (ru) | 2007-09-11 | 2011-10-20 | Мондобайотек Лабораториз Аг (Li) | Применение rgd-пептида и/или паратиреоидного гормона (1-34) в качестве средства против вич |
| MX2010004548A (es) | 2007-10-29 | 2010-05-05 | Virginia Tech Intell Prop | Genes de dc-sign, icam-3 y lsectin porcinas y usos de los mismos. |
| US20110027267A1 (en) | 2007-11-09 | 2011-02-03 | Anaphore, Inc. | Fusion Proteins of Mannose Binding Lectins for Treatment of Disease |
| ES2326109B1 (es) | 2007-12-05 | 2010-06-25 | Consejo Superior De Investigaciones Cientificas | Microdispositivo de separacion y extraccion selectiva y no invasiva de particulas en suspensiones polidispersas, procedimiento de fabricacion y sus aplicaciones. |
| WO2009078015A2 (en) | 2007-12-18 | 2009-06-25 | Procognia (Israel) Ltd | Method and assay for glycosylation pattern detection related to cell state of stem cells |
| JP2011509083A (ja) | 2007-12-31 | 2011-03-24 | スリーエム イノベイティブ プロパティズ カンパニー | 微生物捕捉用組成物及び微生物を捕捉する方法 |
| US20100331240A1 (en) | 2008-01-18 | 2010-12-30 | The General Hospital Corporation | Methods for prevention and treatment of infections with supraphysiological doses of mannan-binding lectin (mbl) and ficolin-mbl fusion proteins |
| KR101625979B1 (ko) | 2008-03-28 | 2016-05-31 | 국립대학법인 홋가이도 다이가쿠 | 항 h5 아형 a형 인플루엔자 바이러스 헤마글루티닌 모노클로날 항체 |
| US20110053145A1 (en) | 2008-03-31 | 2011-03-03 | Japan Tobacco Inc. | Quantitation method of virus |
| AU2009232598A1 (en) | 2008-03-31 | 2009-10-08 | Japan Tobacco Inc. | Enrichment method of virus |
| US20100323429A1 (en) | 2008-04-10 | 2010-12-23 | Yu-Chen Hu | Methods for purifying baculovirus |
| US8865876B2 (en) | 2008-06-02 | 2014-10-21 | California Institute Of Technology | Engineered lectin oligomers with antiviral activity |
| JP2011522044A (ja) | 2008-06-03 | 2011-07-28 | エスティーシー. ユーエヌエム | 免疫性血小板減少症及びループス腎炎における治療有用性が改善されたc反応性タンパク質突然変異体の開発 |
| JP2010122205A (ja) | 2008-08-29 | 2010-06-03 | Sysmex Corp | 麻疹ウイルス検出方法、メンブレンアッセイ用試験具およびメンブレンアッセイ用試験キット |
| WO2010028306A2 (en) | 2008-09-05 | 2010-03-11 | The Regents Of The University Of California Office Of The President | Antibodies with mannose binding lectin effector function for inhibiting pathologic inflammatory conditions |
| WO2010065765A2 (en) | 2008-12-04 | 2010-06-10 | Aethlon Medical, Inc. | Affinity capture of circulating biomarkers |
| CN102325882A (zh) | 2008-12-22 | 2012-01-18 | 国立大学法人北海道大学 | 具有三螺旋结构的蛋白质物质及其制造方法 |
| EP2829550B1 (en) * | 2009-01-09 | 2016-11-16 | Apogenix AG | Fusion proteins forming trimers |
| US20120100140A1 (en) | 2009-01-23 | 2012-04-26 | Biogen Idec Ma Inc. | Stabilized fc polypeptides with reduced effector function and methods of use |
| US20110281792A1 (en) | 2009-01-28 | 2011-11-17 | Zion Todd C | Binding-site modified lectins and uses thereof |
| US20130012451A1 (en) | 2009-12-21 | 2013-01-10 | The Research Foundation Of State University Of New York | Compositions and methods for inhibiting mmp-9-mediated cell migration |
| IN2012DN06589A (en:Method) | 2010-01-19 | 2015-10-23 | Harvard College | |
| US20130157283A1 (en) | 2010-01-19 | 2013-06-20 | President And Fellows Of Harvard College | Rapid pathogen diagnostic device and method |
| JP6228012B2 (ja) | 2011-01-19 | 2017-11-08 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 高圧力安定性、光透過性、および自己修復特性を伴う易滑性表面 |
| JP2014514060A (ja) | 2011-04-01 | 2014-06-19 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 透析様治療(dlt)装置 |
| CA2842321C (en) | 2011-07-18 | 2022-05-03 | President And Fellows Of Harvard College | Engineered microbe-targeting molecules and uses thereof |
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2011
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- 2011-01-19 WO PCT/US2011/021603 patent/WO2011090954A2/en not_active Ceased
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