BR112014023005A2 - diagnóstico rápido e tratamentos personalizados para acne - Google Patents
diagnóstico rápido e tratamentos personalizados para acneInfo
- Publication number
- BR112014023005A2 BR112014023005A2 BR112014023005A BR112014023005A BR112014023005A2 BR 112014023005 A2 BR112014023005 A2 BR 112014023005A2 BR 112014023005 A BR112014023005 A BR 112014023005A BR 112014023005 A BR112014023005 A BR 112014023005A BR 112014023005 A2 BR112014023005 A2 BR 112014023005A2
- Authority
- BR
- Brazil
- Prior art keywords
- acne
- methods
- diagnosing
- personalized
- treating
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0208—Specific bacteria not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/00032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
abstract: fast diagnosis and personalized treatments for acne methods of diagnosing and treating patients afflicted with acne, including diagnosing one as having acne if the individual possesses rt4, rt5, rt7, rt8, rt9, or rt10. methods for treating acne include administering an effective amount of a drug specifically targeting rt4, rt5, rt7, rt8, rt9, or rt10, such as small molecules, antisense molecules, sirnas, biologics, antibodies, phages, vaccines, or combination thereof. tradução do resumo resumo diagnóstico rápido e tratamentos personalizados para acne métodos para diagnosticar e tratar pacientes afligidos com acne, incluindo diagnosticar alguém como tendo acne se o indivíduo possuir rt4, rt5, rt7, rt8, rt9 ou rt10. métodos para tratar acne incluem administrar uma quantidade eficaz de uma droga especificamente dirigida para rt4, rt5, rt7, rt8, rt9 ou rt10, tal como moléculas pequenas, moléculas antissenso, sirnas, biológicos, anticorpos, fagos, vacinas ou combinação dos mesmos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261612290P | 2012-03-17 | 2012-03-17 | |
PCT/US2013/032551 WO2013142378A1 (en) | 2012-03-17 | 2013-03-15 | Fast diagnosis and personalized treatments for acne |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014023005A2 true BR112014023005A2 (pt) | 2017-07-18 |
Family
ID=49223275
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014023005A BR112014023005A2 (pt) | 2012-03-17 | 2013-03-15 | diagnóstico rápido e tratamentos personalizados para acne |
Country Status (10)
Country | Link |
---|---|
US (5) | US20150086581A1 (pt) |
EP (3) | EP3360560A1 (pt) |
JP (3) | JP2015512255A (pt) |
CN (2) | CN104364394B (pt) |
AU (3) | AU2013235340B2 (pt) |
BR (1) | BR112014023005A2 (pt) |
CA (1) | CA2867621A1 (pt) |
HK (1) | HK1207402A1 (pt) |
SG (1) | SG11201405783VA (pt) |
WO (1) | WO2013142378A1 (pt) |
Families Citing this family (108)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9585920B2 (en) | 2011-02-04 | 2017-03-07 | Katherine Rose Kovarik | Method and system for treating cancer cachexia |
US9457077B2 (en) | 2009-11-18 | 2016-10-04 | Katherine Rose Kovarik | Method and system for targeting the microbiome to promote health and treat allergic and inflammatory diseases |
US10842834B2 (en) | 2016-01-06 | 2020-11-24 | Joseph E. Kovarik | Method and system for reducing the likelihood of developing liver cancer in an individual diagnosed with non-alcoholic fatty liver disease |
US11357722B2 (en) | 2011-02-04 | 2022-06-14 | Seed Health, Inc. | Method and system for preventing sore throat in humans |
US10940169B2 (en) | 2015-11-30 | 2021-03-09 | Joseph E. Kovarik | Method for reducing the likelihood of developing cancer in an individual human being |
US10086018B2 (en) | 2011-02-04 | 2018-10-02 | Joseph E. Kovarik | Method and system for reducing the likelihood of colorectal cancer in a human being |
US10687975B2 (en) | 2011-02-04 | 2020-06-23 | Joseph E. Kovarik | Method and system to facilitate the growth of desired bacteria in a human's mouth |
US10314865B2 (en) | 2011-02-04 | 2019-06-11 | Katherine Rose Kovarik | Method and system for treating cancer and other age-related diseases by extending the healthspan of a human |
US11998479B2 (en) | 2011-02-04 | 2024-06-04 | Seed Health, Inc. | Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure |
US11523934B2 (en) | 2011-02-04 | 2022-12-13 | Seed Health, Inc. | Method and system to facilitate the growth of desired bacteria in a human's mouth |
US10245288B2 (en) | 2011-02-04 | 2019-04-02 | Joseph E. Kovarik | Method and system for reducing the likelihood of developing NASH in an individual diagnosed with non-alcoholic fatty liver disease |
US9987224B2 (en) | 2011-02-04 | 2018-06-05 | Joseph E. Kovarik | Method and system for preventing migraine headaches, cluster headaches and dizziness |
US10583033B2 (en) | 2011-02-04 | 2020-03-10 | Katherine Rose Kovarik | Method and system for reducing the likelihood of a porphyromonas gingivalis infection in a human being |
US11844720B2 (en) | 2011-02-04 | 2023-12-19 | Seed Health, Inc. | Method and system to reduce the likelihood of dental caries and halitosis |
US10835560B2 (en) | 2013-12-20 | 2020-11-17 | Joseph E. Kovarik | Reducing the likelihood of skin cancer in an individual human being |
US11273187B2 (en) | 2015-11-30 | 2022-03-15 | Joseph E. Kovarik | Method and system for reducing the likelihood of developing depression in an individual |
US11191665B2 (en) | 2011-02-04 | 2021-12-07 | Joseph E. Kovarik | Method and system for reducing the likelihood of a porphyromonas gingivalis infection in a human being |
US10111913B2 (en) | 2011-02-04 | 2018-10-30 | Joseph E. Kovarik | Method of reducing the likelihood of skin cancer in an individual human being |
US10548761B2 (en) | 2011-02-04 | 2020-02-04 | Joseph E. Kovarik | Method and system for reducing the likelihood of colorectal cancer in a human being |
US10085938B2 (en) | 2011-02-04 | 2018-10-02 | Joseph E. Kovarik | Method and system for preventing sore throat in humans |
US10512661B2 (en) | 2011-02-04 | 2019-12-24 | Joseph E. Kovarik | Method and system for reducing the likelihood of developing liver cancer in an individual diagnosed with non-alcoholic fatty liver disease |
US9730967B2 (en) | 2011-02-04 | 2017-08-15 | Katherine Rose Kovarik | Method and system for treating cancer cachexia |
US11419903B2 (en) | 2015-11-30 | 2022-08-23 | Seed Health, Inc. | Method and system for reducing the likelihood of osteoporosis |
US11951140B2 (en) | 2011-02-04 | 2024-04-09 | Seed Health, Inc. | Modulation of an individual's gut microbiome to address osteoporosis and bone disease |
US11951139B2 (en) | 2015-11-30 | 2024-04-09 | Seed Health, Inc. | Method and system for reducing the likelihood of osteoporosis |
US10010568B2 (en) | 2011-02-04 | 2018-07-03 | Katherine Rose Kovarik | Method and system for reducing the likelihood of a spirochetes infection in a human being |
AU2012333134B2 (en) | 2011-07-22 | 2017-05-25 | John Paul Guilinger | Evaluation and improvement of nuclease cleavage specificity |
EP3360560A1 (en) | 2012-03-17 | 2018-08-15 | The Regents of the University of California | Composition for treating acne |
JP2016528880A (ja) | 2013-06-18 | 2016-09-23 | プロダームアイキュー インコーポレイテッド | 皮膚細菌叢の解析に基づくカスタマイズしたスキンケア製品及びパーソナルケア製品 |
WO2015013214A2 (en) | 2013-07-21 | 2015-01-29 | Whole Biome, Inc. | Methods and systems for microbiome characterization, monitoring and treatment |
US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
US9340800B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | Extended DNA-sensing GRNAS |
US9737604B2 (en) | 2013-09-06 | 2017-08-22 | President And Fellows Of Harvard College | Use of cationic lipids to deliver CAS9 |
WO2015070083A1 (en) | 2013-11-07 | 2015-05-14 | Editas Medicine,Inc. | CRISPR-RELATED METHODS AND COMPOSITIONS WITH GOVERNING gRNAS |
US9068179B1 (en) | 2013-12-12 | 2015-06-30 | President And Fellows Of Harvard College | Methods for correcting presenilin point mutations |
US11826388B2 (en) | 2013-12-20 | 2023-11-28 | Seed Health, Inc. | Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation |
US11529379B2 (en) | 2013-12-20 | 2022-12-20 | Seed Health, Inc. | Method and system for reducing the likelihood of developing colorectal cancer in an individual human being |
US11642382B2 (en) | 2013-12-20 | 2023-05-09 | Seed Health, Inc. | Method for treating an individual suffering from bladder cancer |
US11980643B2 (en) | 2013-12-20 | 2024-05-14 | Seed Health, Inc. | Method and system to modify an individual's gut-brain axis to provide neurocognitive protection |
US11969445B2 (en) | 2013-12-20 | 2024-04-30 | Seed Health, Inc. | Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH |
US11026982B2 (en) | 2015-11-30 | 2021-06-08 | Joseph E. Kovarik | Method for reducing the likelihood of developing bladder or colorectal cancer in an individual human being |
US11672835B2 (en) | 2013-12-20 | 2023-06-13 | Seed Health, Inc. | Method for treating individuals having cancer and who are receiving cancer immunotherapy |
US11213552B2 (en) | 2015-11-30 | 2022-01-04 | Joseph E. Kovarik | Method for treating an individual suffering from a chronic infectious disease and cancer |
US11833177B2 (en) | 2013-12-20 | 2023-12-05 | Seed Health, Inc. | Probiotic to enhance an individual's skin microbiome |
US12005085B2 (en) | 2013-12-20 | 2024-06-11 | Seed Health, Inc. | Probiotic method and composition for maintaining a healthy vaginal microbiome |
US11839632B2 (en) | 2013-12-20 | 2023-12-12 | Seed Health, Inc. | Topical application of CRISPR-modified bacteria to treat acne vulgaris |
US11998574B2 (en) | 2013-12-20 | 2024-06-04 | Seed Health, Inc. | Method and system for modulating an individual's skin microbiome |
WO2015171899A1 (en) | 2014-05-07 | 2015-11-12 | The Regents Of The University Of California | Compositions and methods for treating skin and mucous membrane diseases |
JP2017521059A (ja) | 2014-06-17 | 2017-08-03 | ザイクローブ セラピューティクス, インク.Xycrobe Therapeutics, Inc. | 機械的に位置合わせされた光学的要素及びその製造方法 |
AU2015298571B2 (en) | 2014-07-30 | 2020-09-03 | President And Fellows Of Harvard College | Cas9 proteins including ligand-dependent inteins |
US9970030B2 (en) | 2014-08-27 | 2018-05-15 | Caribou Biosciences, Inc. | Methods for increasing CAS9-mediated engineering efficiency |
US10169541B2 (en) | 2014-10-21 | 2019-01-01 | uBiome, Inc. | Method and systems for characterizing skin related conditions |
WO2016065075A1 (en) | 2014-10-21 | 2016-04-28 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics |
US10410749B2 (en) | 2014-10-21 | 2019-09-10 | uBiome, Inc. | Method and system for microbiome-derived characterization, diagnostics and therapeutics for cutaneous conditions |
WO2016168350A1 (en) * | 2015-04-13 | 2016-10-20 | uBiome, Inc. | Method and system for microbiome-derived characterization, diagnostics and therapeutics for cutaneous conditions |
CA3021690A1 (en) | 2015-04-20 | 2016-10-27 | S-Biomedic Nv | Methods and compositions for changing the composition of the skin microbiome using complex mixtures of bacterial strains |
JP6046849B1 (ja) * | 2015-07-21 | 2016-12-21 | TAK−Circulator株式会社 | 身体状態の評価方法、情報の提示方法、および身体状態を改善又は予防する物質のスクリーニング方法 |
WO2017021529A1 (en) * | 2015-08-06 | 2017-02-09 | Curetis Gmbh | Genetic resistance prediction against antimicrobial drugs in microorganism using structural changes in the genome |
WO2017044871A1 (en) * | 2015-09-09 | 2017-03-16 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for eczema |
CA3005985A1 (en) | 2015-09-09 | 2017-03-16 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics of infectious disease and other health conditions associated with antibiotic usage |
WO2017044885A1 (en) * | 2015-09-09 | 2017-03-16 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with cerebro-craniofacial health |
WO2017049103A1 (en) | 2015-09-17 | 2017-03-23 | Prodermiq, Inc. | Predicting skin age based on the analysis of skin flora and lifestyle data |
WO2017070632A2 (en) | 2015-10-23 | 2017-04-27 | President And Fellows Of Harvard College | Nucleobase editors and uses thereof |
JP6872222B2 (ja) * | 2015-11-04 | 2021-05-19 | 学校法人慶應義塾 | 対象物の使用者を判定する方法 |
GB2544481B (en) * | 2015-11-16 | 2019-12-11 | Century International Enterprises Ltd | A wearable article and a method for producing a wearable article |
US11529412B2 (en) | 2015-11-30 | 2022-12-20 | Seed Health, Inc. | Method and system for protecting honey bees from pesticides |
US10086024B2 (en) | 2015-11-30 | 2018-10-02 | Joseph E. Kovarik | Method and system for protecting honey bees, bats and butterflies from neonicotinoid pesticides |
US10568916B2 (en) | 2015-11-30 | 2020-02-25 | Joseph E. Kovarik | Method and system for protecting honey bees, bats and butterflies from neonicotinoid pesticides |
US10933128B2 (en) | 2015-11-30 | 2021-03-02 | Joseph E. Kovarik | Method and system for protecting honey bees from pesticides |
US10675347B2 (en) | 2015-11-30 | 2020-06-09 | Joseph E. Kovarik | Method and system for protecting honey bees from fipronil pesticides |
JP2019509263A (ja) * | 2016-02-05 | 2019-04-04 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 皮膚の健康増進用組成物及び健康増進方法 |
WO2017147507A1 (en) | 2016-02-24 | 2017-08-31 | Xycrobe Therapeutics, Inc. | Skin probiotic formulation |
US20190336542A1 (en) * | 2016-04-21 | 2019-11-07 | Naked Biome, Inc. | Synthetic bacteria and methods of use |
US9889165B2 (en) | 2016-04-21 | 2018-02-13 | Naked Biome, Inc. | Compositions and methods for treatment of skin disorders |
WO2017189614A1 (en) * | 2016-04-25 | 2017-11-02 | uBiome, Inc. | Method and system for characterizing skin related conditions |
EP3243907A1 (en) * | 2016-05-13 | 2017-11-15 | Curetis GmbH | Stable pan-genomes and their use |
KR20190039473A (ko) * | 2016-05-15 | 2019-04-12 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 여드름 치료를 위한 조성물 및 방법 |
CN106167820A (zh) * | 2016-05-19 | 2016-11-30 | 胤安国际(辽宁)基因科技股份有限公司 | 鉴定或辅助鉴定痤疮丙酸杆菌的专用引物及其应用 |
US11913061B2 (en) | 2016-07-08 | 2024-02-27 | Kao Corporation | Method for preparing nucleic acid sample |
CN113481294B (zh) * | 2016-07-08 | 2024-03-12 | 花王株式会社 | 核酸样品的制备方法 |
CA3032699A1 (en) | 2016-08-03 | 2018-02-08 | President And Fellows Of Harvard College | Adenosine nucleobase editors and uses thereof |
WO2018031683A1 (en) | 2016-08-09 | 2018-02-15 | President And Fellows Of Harvard College | Programmable cas9-recombinase fusion proteins and uses thereof |
WO2018039438A1 (en) | 2016-08-24 | 2018-03-01 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
EP3526320A1 (en) | 2016-10-14 | 2019-08-21 | President and Fellows of Harvard College | Aav delivery of nucleobase editors |
ES2967029T3 (es) | 2016-10-19 | 2024-04-25 | S Biomedic Nv | Métodos y composiciones para cambiar la composición del microbioma de la piel usando mezclas complejas de cepas bacterianas |
JP6815006B2 (ja) | 2016-11-01 | 2021-01-20 | 株式会社桃谷順天館 | アクネ菌株選択的抗菌剤 |
US20200121744A1 (en) * | 2016-11-08 | 2020-04-23 | The Regents Of The University Of California | Compositions and methods for treating skin diseases and maintaining healthy skin |
US11915795B2 (en) * | 2016-12-23 | 2024-02-27 | The Regents Of The University Of California | Method and device for digital high resolution melt |
US10745677B2 (en) | 2016-12-23 | 2020-08-18 | President And Fellows Of Harvard College | Editing of CCR5 receptor gene to protect against HIV infection |
EP3592853A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Suppression of pain by gene editing |
JP2020510439A (ja) | 2017-03-10 | 2020-04-09 | プレジデント アンド フェローズ オブ ハーバード カレッジ | シトシンからグアニンへの塩基編集因子 |
KR20200019116A (ko) | 2017-03-10 | 2020-02-21 | 프로더믹, 인코포레이티드 | 피부 균총의 분석에 기반한 맞춤형 피부 케어 제품 및 개인 케어 제품 |
KR102687373B1 (ko) | 2017-03-23 | 2024-07-23 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제 |
CA3060415A1 (en) | 2017-04-21 | 2018-10-25 | Phi Therapeutics, Inc. | Compositions comprising propionibacterium acnes bacteriophages for treating acne |
WO2018209320A1 (en) | 2017-05-12 | 2018-11-15 | President And Fellows Of Harvard College | Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation |
EP3658573A1 (en) | 2017-07-28 | 2020-06-03 | President and Fellows of Harvard College | Methods and compositions for evolving base editors using phage-assisted continuous evolution (pace) |
WO2019139645A2 (en) | 2017-08-30 | 2019-07-18 | President And Fellows Of Harvard College | High efficiency base editors comprising gam |
CN111757937A (zh) | 2017-10-16 | 2020-10-09 | 布罗德研究所股份有限公司 | 腺苷碱基编辑器的用途 |
WO2019079612A1 (en) * | 2017-10-20 | 2019-04-25 | Naked Biome, Inc. | SYSTEMS AND METHODS OF BACTERIAL DETECTION AND TREATMENT |
CN111867608A (zh) * | 2017-12-05 | 2020-10-30 | 拜欧麦克斯有限公司 | 用于痤疮和生物膜的噬菌体治疗 |
JP2020074769A (ja) * | 2018-11-01 | 2020-05-21 | 花王株式会社 | 被験体の皮膚細胞に由来する核酸の調製方法 |
WO2020191249A1 (en) | 2019-03-19 | 2020-09-24 | The Broad Institute, Inc. | Methods and compositions for editing nucleotide sequences |
JP7341310B2 (ja) * | 2019-07-10 | 2023-09-08 | ジャン・ルオウェイ | 皮膚分析のための画像処理、皮膚分析を視覚化するためのシステム及び方法 |
EP4003381A4 (en) * | 2019-07-22 | 2024-02-28 | The Regents of the University of California | COMPOSITIONS AND METHODS FOR TREATING SKIN INFECTIONS AND OTHER DISEASES |
WO2021087415A1 (en) * | 2019-10-31 | 2021-05-06 | University Of Maryland, College Park | Method of treating infections by bacteriolytic enzymes and manufacture thereof |
MX2022014008A (es) | 2020-05-08 | 2023-02-09 | Broad Inst Inc | Métodos y composiciones para la edición simultánea de ambas cadenas de una secuencia de nucleótidos de doble cadena objetivo. |
CN113066533B (zh) * | 2021-04-02 | 2023-04-04 | 欧蒙医学诊断(中国)有限公司 | 一种mNGS病原体数据分析方法 |
Family Cites Families (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU670777B2 (en) | 1992-04-16 | 1996-08-01 | Ortho Pharmaceutical Corporation | Aqueous gel vehicles for retinoids |
US5836999A (en) | 1995-09-28 | 1998-11-17 | Esc Medical Systems Ltd. | Method and apparatus for treating psoriasis using pulsed electromagnetic radiation |
US6121036A (en) | 1996-04-15 | 2000-09-19 | Ghanbari; Hossein A. | Compositions containing bacteriophages and methods of using bacteriophages to treat infections |
JPH11171783A (ja) | 1997-08-15 | 1999-06-29 | Vetoquinol Sa | 所定の動物に関して細胞性免疫と体重増加を生じる濃度でのバクテリアの経口投与 |
JP2002516665A (ja) * | 1998-05-22 | 2002-06-11 | クリートゲン アクチエンゲゼルシャフト | 微生物における抗生物質耐性の検出 |
US6726913B1 (en) | 1999-10-15 | 2004-04-27 | The Van Kampen Group, Inc. | Treatment of dermal tumors, warts, and viral infections of the respiratory tract in humans using heat-killed P. acnes |
CA2407352A1 (en) | 2000-04-21 | 2001-11-01 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of acne vulgaris |
PE20030284A1 (es) * | 2001-07-26 | 2003-05-01 | Alimentary Health Ltd | Cepas de bifidobacterium |
WO2003033515A1 (en) | 2001-10-15 | 2003-04-24 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of acne vulgaris |
US20040157837A1 (en) | 2002-11-07 | 2004-08-12 | Serbedzija George N. | Combinations for the treatment of fungal infections |
NZ539076A (en) * | 2005-03-29 | 2008-05-30 | Blis Technologies Ltd | Skin treatment compositions |
EP1907534B2 (en) * | 2005-07-12 | 2024-04-10 | Micreos B.V. | Bacteriophage and their uses |
WO2007056680A2 (en) | 2005-11-03 | 2007-05-18 | Forsyth Dental Infirmary For Children | Methods and arrays for identifying human microflora |
JP5201818B2 (ja) * | 2006-11-10 | 2013-06-05 | キヤノン株式会社 | プローブセット、プローブ固定担体及び遺伝子検査方法 |
WO2009018447A2 (en) | 2007-07-31 | 2009-02-05 | New York University | Diagnostic and treatment methods for characterizing bacterial microbiota in skin conditions |
EP2082736A1 (fr) * | 2008-01-23 | 2009-07-29 | Jean Hilaire Saurat | Composition pharmaceutique à usage topique |
US20090269764A1 (en) * | 2008-02-19 | 2009-10-29 | Gen-Probe Incorporated | Compositions and methods for detection of propionibacterium acnes nucleic acid |
EP2381920A4 (en) | 2008-12-05 | 2013-04-17 | Univ California | METHOD AND COMPOSITIONS FOR TREATING P.ACNES |
US9457077B2 (en) * | 2009-11-18 | 2016-10-04 | Katherine Rose Kovarik | Method and system for targeting the microbiome to promote health and treat allergic and inflammatory diseases |
SG194420A1 (en) * | 2010-05-27 | 2013-12-30 | Kenichiro Hasumi | Antigen peptide and use thereof |
EP3360560A1 (en) * | 2012-03-17 | 2018-08-15 | The Regents of the University of California | Composition for treating acne |
EP2664919A1 (fr) * | 2012-05-15 | 2013-11-20 | Jean Hilaire Saurat | Une méthode pour identifier les ligands du récepteur AhR possédant une activité sebosuppressive thérapeutique |
CN104704127A (zh) * | 2012-07-13 | 2015-06-10 | 莱雅公司 | 体外诊断受试者的薄皮状态的方法及相关应用 |
WO2014025938A1 (en) | 2012-08-07 | 2014-02-13 | TopGeniX, Inc. | Topical composition comprising transformed bacteria expressing a compound of interest |
US8906668B2 (en) * | 2012-11-23 | 2014-12-09 | Seres Health, Inc. | Synergistic bacterial compositions and methods of production and use thereof |
EP3584308A3 (en) * | 2013-02-04 | 2020-03-04 | Seres Therapeutics, Inc. | Compositions and methods |
RU2722482C2 (ru) * | 2013-11-25 | 2020-06-01 | Серес Терапеутикс, Инк. | Синергические бактериальные композиции и способы их получения и применения |
US9737592B1 (en) * | 2014-02-14 | 2017-08-22 | David Gordon Bermudes | Topical and orally administered protease inhibitors and bacterial vectors for the treatment of disorders and methods of treatment |
WO2015171899A1 (en) * | 2014-05-07 | 2015-11-12 | The Regents Of The University Of California | Compositions and methods for treating skin and mucous membrane diseases |
JP2017521059A (ja) * | 2014-06-17 | 2017-08-03 | ザイクローブ セラピューティクス, インク.Xycrobe Therapeutics, Inc. | 機械的に位置合わせされた光学的要素及びその製造方法 |
US20190008930A1 (en) * | 2015-07-31 | 2019-01-10 | The Regents Of The University Of California | Mycobacterium lysterase: a novel treatment for acne |
JP2019509263A (ja) * | 2016-02-05 | 2019-04-04 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 皮膚の健康増進用組成物及び健康増進方法 |
US9889165B2 (en) * | 2016-04-21 | 2018-02-13 | Naked Biome, Inc. | Compositions and methods for treatment of skin disorders |
KR20190039473A (ko) * | 2016-05-15 | 2019-04-12 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 여드름 치료를 위한 조성물 및 방법 |
ES2967029T3 (es) * | 2016-10-19 | 2024-04-25 | S Biomedic Nv | Métodos y composiciones para cambiar la composición del microbioma de la piel usando mezclas complejas de cepas bacterianas |
CN111867608A (zh) * | 2017-12-05 | 2020-10-30 | 拜欧麦克斯有限公司 | 用于痤疮和生物膜的噬菌体治疗 |
AU2021297215A1 (en) * | 2020-06-23 | 2023-02-09 | Crown Laboratories, Inc. | Probiotic skin formulations |
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HK1207402A1 (en) | 2016-01-29 |
SG11201405783VA (en) | 2014-10-30 |
EP2825676A1 (en) | 2015-01-21 |
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CN110055320A (zh) | 2019-07-26 |
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