IL98255A - Biocompatible perforated membranes, processes for their preparation, their use as a support in the in vitro growth of epithelial cells, the artificial skin obtained in this manner, and its use in skin grafts - Google Patents

Biocompatible perforated membranes, processes for their preparation, their use as a support in the in vitro growth of epithelial cells, the artificial skin obtained in this manner, and its use in skin grafts

Info

Publication number
IL98255A
IL98255A IL98255A IL9825591A IL98255A IL 98255 A IL98255 A IL 98255A IL 98255 A IL98255 A IL 98255A IL 9825591 A IL9825591 A IL 9825591A IL 98255 A IL98255 A IL 98255A
Authority
IL
Israel
Prior art keywords
processes
preparation
manner
support
epithelial cells
Prior art date
Application number
IL98255A
Other languages
English (en)
Other versions
IL98255A0 (en
Inventor
Francesco Della Valle
Gabriella Calderini
Alessandro Rastrelli
Aurelio Romeo
Original Assignee
Fidia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Spa filed Critical Fidia Spa
Publication of IL98255A0 publication Critical patent/IL98255A0/xx
Publication of IL98255A publication Critical patent/IL98255A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0629—Keratinocytes; Whole skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/10—Hair or skin implants
    • A61F2/105—Skin implants, e.g. artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/80—Hyaluronan
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2539/00—Supports and/or coatings for cell culture characterised by properties
    • C12N2539/10—Coating allowing for selective detachment of cells, e.g. thermoreactive coating
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24273—Structurally defined web or sheet [e.g., overall dimension, etc.] including aperture

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL98255A 1990-06-01 1991-05-24 Biocompatible perforated membranes, processes for their preparation, their use as a support in the in vitro growth of epithelial cells, the artificial skin obtained in this manner, and its use in skin grafts IL98255A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02051390A IT1248934B (it) 1990-06-01 1990-06-01 Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle

Publications (2)

Publication Number Publication Date
IL98255A0 IL98255A0 (en) 1992-06-21
IL98255A true IL98255A (en) 1997-11-20

Family

ID=11168072

Family Applications (1)

Application Number Title Priority Date Filing Date
IL98255A IL98255A (en) 1990-06-01 1991-05-24 Biocompatible perforated membranes, processes for their preparation, their use as a support in the in vitro growth of epithelial cells, the artificial skin obtained in this manner, and its use in skin grafts

Country Status (24)

Country Link
US (3) US5326356A (fi)
EP (1) EP0462426B1 (fi)
JP (1) JP3202257B2 (fi)
KR (1) KR100195574B1 (fi)
AR (1) AR244354A1 (fi)
AT (1) ATE156689T1 (fi)
AU (1) AU637235B2 (fi)
BR (1) BR9102225A (fi)
CA (1) CA2043527C (fi)
DE (1) DE69127235T2 (fi)
DK (1) DK0462426T3 (fi)
ES (1) ES2108019T3 (fi)
FI (1) FI108918B (fi)
GR (1) GR3025075T3 (fi)
HU (1) HU215534B (fi)
IE (1) IE911825A1 (fi)
IL (1) IL98255A (fi)
IT (1) IT1248934B (fi)
NO (1) NO303562B1 (fi)
PT (1) PT97832B (fi)
SG (1) SG52545A1 (fi)
TW (1) TW208652B (fi)
UY (1) UY23231A1 (fi)
ZA (1) ZA914098B (fi)

Families Citing this family (163)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10237531A1 (de) 2002-08-16 2004-02-26 Tutogen Medical Gmbh Implantat
US6033437A (en) 1991-09-30 2000-03-07 Orbital Implant Technology Pegs for orbital implants
IT1263144B (it) * 1993-02-04 1996-08-01 Lanfranco Callegaro Composizioni farmaceutiche comprendenti materiale spugnoso costituito da derivati esterei dell'acido ialuronico in associazione con altre sostanze farmacologicamente attive
IT1263316B (it) * 1993-02-12 1996-08-05 Fidia Advanced Biopolymers Srl Tessuto non tessuto multistrato in cui uno degli strati e' costituito essenzialmente da esteri dell'acido ialuronico
US6176874B1 (en) * 1993-10-18 2001-01-23 Masschusetts Institute Of Technology Vascularized tissue regeneration matrices formed by solid free form fabrication techniques
DE4426315C1 (de) * 1994-07-25 1996-03-21 Gore W L & Ass Gmbh Membran zur Regeneration von Körpergeweben und Verwendung der Membran als Wundabdeckung und Hautersatz
US6294202B1 (en) * 1994-10-06 2001-09-25 Genzyme Corporation Compositions containing polyanionic polysaccharides and hydrophobic bioabsorbable polymers
JP3543869B2 (ja) * 1995-03-07 2004-07-21 株式会社メニコン 培養皮膚およびその製造法
IT1281870B1 (it) * 1995-04-27 1998-03-03 Fidia Advanced Biopolymers Srl Pelle artificiale umana costituita da materiali biocompatibili a base di derivati dell'acido ialuronico
US20040002772A1 (en) * 1995-04-28 2004-01-01 Organogenesis, Inc. Tissue equivalents with perforations for improved integration to host tissues and methods for producing perforated tissue equivalents
GB9512529D0 (en) * 1995-06-20 1995-08-23 Bnfl Fluorchem Ltd Cell treatment
US5693332C1 (en) * 1995-08-11 2001-01-09 Univ California Human keratinocytes supported on a hydrophilic membrane and methods of using same to effect wound closure
AU6775596A (en) * 1995-08-16 1997-03-12 Integra Lifesciences Corporation Perforated artificial skin grafts
PL186859B1 (pl) * 1995-08-29 2004-03-31 Fidia Advanced Biopolymers Biomateriał do zapobiegania zrostom tkanek po zabiegu chirurgicznym i zastosowanie biomateriału
IT1282207B1 (it) * 1995-11-20 1998-03-16 Fidia Advanced Biopolymers Srl Sistemi di coltura di cellule staminali di midollo osseo umano in matrici tridimensionali costituiti da esteri dell'acido ialuronico
WO1997045532A1 (en) * 1996-05-28 1997-12-04 Brown University Research Foundation Hyaluronan based biodegradable scaffolds for tissue repair
US5919234A (en) * 1996-08-19 1999-07-06 Macropore, Inc. Resorbable, macro-porous, non-collapsing and flexible membrane barrier for skeletal repair and regeneration
US6306491B1 (en) 1996-12-20 2001-10-23 Gore Enterprise Holdings, Inc. Respiratory aids
US7192450B2 (en) 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US20050033132A1 (en) 1997-03-04 2005-02-10 Shults Mark C. Analyte measuring device
US6741877B1 (en) 1997-03-04 2004-05-25 Dexcom, Inc. Device and method for determining analyte levels
TW586934B (en) * 1997-05-19 2004-05-11 Sumitomo Pharma Immunopotentiating composition
ES2132027B1 (es) * 1997-07-04 2000-04-01 Comunitario De Transfusion Del Desarrollo de una piel artificial mediante cultivo de queratinocitos sobre una base de fibrina y fibroblastos humanos y metodo de preparacion de esta piel para trasplante.
US6063117A (en) * 1998-01-22 2000-05-16 Perry; Arthur C. Porous orbital implant structure
EP1282383A4 (en) * 1998-01-23 2007-08-08 Macropore Inc MEMBRANE BARRIER LIKELY RESIN, MACROPOROUS, WITH NO SAGING AND FLEXIBLE RISK FOR REPAIR AND REGENERATION OF SKELETON
JP2002510530A (ja) 1998-04-07 2002-04-09 マクロポア インコーポレイテッド 組織案内表面波形部付きのメンブレン
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
ITPD980149A1 (it) 1998-06-17 1999-12-17 Fidia Advanced Biopolymers Srl Protesi tridimensionali comprendenti derivati dell'acido ialuronico per riparare o ricostruire i tessuti danneggiati e processo per la
US5976150A (en) * 1998-08-25 1999-11-02 Alcon Laboratories, Inc. Intraocular lens injection system
US6278079B1 (en) 1999-02-09 2001-08-21 Edwards Lifesciences Corp. Laser cutting of fabric grafts
FR2792650B1 (fr) 1999-04-20 2003-02-28 Oreal Equivalent de peau agee, son procede de preparation et son utilisation
WO2000066055A1 (fr) * 1999-04-30 2000-11-09 Boris Alexeevich Paramonov Bandage
DE19922078A1 (de) * 1999-05-15 2000-11-23 Weitzel Kage Doris Gewebekonstrukt für die Transplantationschirurgie
IT1306679B1 (it) * 1999-06-29 2001-10-02 Fidia Advanced Biopolymers Srl Uso dei derivati dell'acido ialuronico per la preparazione dicomposizoni farmaceutiche e biomateriali per la prevenzione della
US6733530B1 (en) * 1999-08-02 2004-05-11 Eric Sun-Yin Chan Material and method for engraftment of a composite biocompatible skin graft on the neodermis of artificial skin
JP4675018B2 (ja) * 1999-12-03 2011-04-20 ユニバーシティ オブ リーズ 損傷を受けた組織の修復
DE19959750C1 (de) * 1999-12-11 2001-05-31 Axel Thierauf Verfahren zur Herstellung eines Hautimplantats, insbesondere Eigenhaut-Implantat und nach dem Verfahren hergestelltes Implantat
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US6974697B2 (en) * 2001-03-02 2005-12-13 Stratech Corporation Skin substitutes with improved barrier function
PT1404809E (pt) * 2001-03-02 2014-03-20 Stratatech Corp Substitutos de pele melhorados e suas utilizações
US7041468B2 (en) 2001-04-02 2006-05-09 Therasense, Inc. Blood glucose tracking apparatus and methods
DE10135676A1 (de) * 2001-07-21 2003-02-06 Degussa Bioactives Deutschland Physiologisch verträglicher, Cellulose enthaltender Film
US6702857B2 (en) 2001-07-27 2004-03-09 Dexcom, Inc. Membrane for use with implantable devices
US20030032874A1 (en) 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
DE10151296A1 (de) * 2001-10-17 2003-04-30 Boehringer Ingelheim Pharma Keratinozyten verwendbar als biologisch aktive Substanz bei der Behandlung von Wunden
KR20030032420A (ko) * 2001-10-18 2003-04-26 한국과학기술연구원 손상된 안구 조직의 재생을 위한 생분해성 고분자로제조된 다공성 지지체
US8364229B2 (en) 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US9247901B2 (en) 2003-08-22 2016-02-02 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
EP1549738B1 (en) 2002-04-30 2010-04-21 Stratatech Corporation Keratinocytes expressing exogenous angiogenic growth factors
US7226978B2 (en) 2002-05-22 2007-06-05 Dexcom, Inc. Techniques to improve polyurethane membranes for implantable glucose sensors
AU2003249310A1 (en) * 2002-07-17 2004-02-02 Proxy Biomedical Limited Soft tissue implants and methods for making same
WO2004028584A1 (en) * 2002-09-30 2004-04-08 Bioland Ltd. Dermal substitute consisting of amnion and biodegradable polymer, the preparation method and the use thereof
US8685943B2 (en) 2003-03-12 2014-04-01 Hill's Pet Nutrition, Inc. Methods for reducing diarrhea in a companion animal
US7134999B2 (en) 2003-04-04 2006-11-14 Dexcom, Inc. Optimized sensor geometry for an implantable glucose sensor
US7875293B2 (en) 2003-05-21 2011-01-25 Dexcom, Inc. Biointerface membranes incorporating bioactive agents
EP1635782A1 (de) * 2003-05-24 2006-03-22 JUVENA (International) AG Gewebekulturmedien als bestandteil von kosmetika
US8423113B2 (en) 2003-07-25 2013-04-16 Dexcom, Inc. Systems and methods for processing sensor data
US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7761130B2 (en) 2003-07-25 2010-07-20 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US7778680B2 (en) 2003-08-01 2010-08-17 Dexcom, Inc. System and methods for processing analyte sensor data
NZ545404A (en) 2003-08-01 2009-12-24 Stratatech Corp Human skin equivalents expressing exogenous polypeptides
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US8160669B2 (en) 2003-08-01 2012-04-17 Dexcom, Inc. Transcutaneous analyte sensor
US20080119703A1 (en) 2006-10-04 2008-05-22 Mark Brister Analyte sensor
US8845536B2 (en) 2003-08-01 2014-09-30 Dexcom, Inc. Transcutaneous analyte sensor
US8622905B2 (en) 2003-08-01 2014-01-07 Dexcom, Inc. System and methods for processing analyte sensor data
JP4863714B2 (ja) * 2003-08-07 2012-01-25 旭化成クラレメディカル株式会社 複合多孔膜とその製造方法
US20140121989A1 (en) 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
WO2005051170A2 (en) 2003-11-19 2005-06-09 Dexcom, Inc. Integrated receiver for continuous analyte sensor
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US8615282B2 (en) 2004-07-13 2013-12-24 Dexcom, Inc. Analyte sensor
EP2239566B1 (en) 2003-12-05 2014-04-23 DexCom, Inc. Calibration techniques for a continuous analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
EP1711791B1 (en) 2003-12-09 2014-10-15 DexCom, Inc. Signal processing for continuous analyte sensor
WO2005079257A2 (en) * 2004-02-12 2005-09-01 Dexcom, Inc. Biointerface with macro- and micro- architecture
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
WO2009048462A1 (en) 2007-10-09 2009-04-16 Dexcom, Inc. Integrated insulin delivery system with continuous glucose sensor
US8715340B2 (en) 2004-03-31 2014-05-06 Merlin Md Pte Ltd. Endovascular device with membrane
US8915952B2 (en) * 2004-03-31 2014-12-23 Merlin Md Pte Ltd. Method for treating aneurysms
US8500751B2 (en) 2004-03-31 2013-08-06 Merlin Md Pte Ltd Medical device
US20050245799A1 (en) * 2004-05-03 2005-11-03 Dexcom, Inc. Implantable analyte sensor
US8792955B2 (en) 2004-05-03 2014-07-29 Dexcom, Inc. Transcutaneous analyte sensor
HUP0401054A2 (en) * 2004-05-26 2006-07-28 Dr Juhasz Zsuzsanna Rethyne Process for growing of living tissue on living organism
DK1761220T3 (da) * 2004-06-30 2010-03-15 Coloplast As Hudpladeklæberprodukt og fremgangsmåde til fremstiling deraf
US8565848B2 (en) 2004-07-13 2013-10-22 Dexcom, Inc. Transcutaneous analyte sensor
US7310544B2 (en) 2004-07-13 2007-12-18 Dexcom, Inc. Methods and systems for inserting a transcutaneous analyte sensor
US7905833B2 (en) 2004-07-13 2011-03-15 Dexcom, Inc. Transcutaneous analyte sensor
US7783333B2 (en) 2004-07-13 2010-08-24 Dexcom, Inc. Transcutaneous medical device with variable stiffness
US8452368B2 (en) 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
US20070045902A1 (en) 2004-07-13 2007-03-01 Brauker James H Analyte sensor
US20060029633A1 (en) * 2004-08-03 2006-02-09 Arthrotek, Inc Biological patch for use in medical procedures
WO2006094070A2 (en) 2005-03-01 2006-09-08 Stratatech Corporation Human skin equivalents expressing exogenous polypeptides
ES2622508T3 (es) 2005-03-17 2017-07-06 Stratatech Corporation Sustitutos de piel con pureza mejorada
JP4716092B2 (ja) * 2005-03-31 2011-07-06 オリンパステルモバイオマテリアル株式会社 タンパク質多孔マトリックスの製造方法
JP2007006987A (ja) * 2005-06-28 2007-01-18 Hokkaido Univ 皮膚再生用の細胞シートを作製するための構造体およびその利用
GB0513552D0 (en) 2005-07-01 2005-08-10 Bristol Myers Squibb Co Bandage
US20070038299A1 (en) * 2005-08-12 2007-02-15 Arthrotek, Inc Multilayer microperforated implant
EP1937183B1 (en) 2005-09-12 2018-11-28 Proxy Biomedical Limited Soft tissue implants
AU2006304229A1 (en) 2005-10-13 2007-04-26 Synthes Gmbh Drug-impregnated encasement
WO2007087402A2 (en) 2006-01-24 2007-08-02 Brown University Cell aggregation and encapsulation device and method
US20070185238A1 (en) * 2006-02-06 2007-08-09 No-Burn Investments, Llc Paint with mold inhibitor and insecticide
EP1991110B1 (en) 2006-03-09 2018-11-07 DexCom, Inc. Systems and methods for processing analyte sensor data
US20080071157A1 (en) 2006-06-07 2008-03-20 Abbott Diabetes Care, Inc. Analyte monitoring system and method
WO2008017170A1 (en) * 2006-08-10 2008-02-14 Ao Technology Ag Biomedical polymer material for tissue repair and engineering
TWI349554B (en) * 2007-03-30 2011-10-01 Univ Kyushu Nat Univ Corp Method for producing three-dimensional structures of cells
US20200037874A1 (en) 2007-05-18 2020-02-06 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
EP2152350A4 (en) 2007-06-08 2013-03-27 Dexcom Inc INTEGRATED MEDICINE DELIVERY DEVICE FOR USE WITH A CONTINUOUS ANALYZING SUBSTANCE SENSOR
DE102007028423A1 (de) 2007-06-20 2008-12-24 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren und Vorrichtung zur Bildung von Aggregaten biologischer Zellen
US20090123766A1 (en) * 2007-11-13 2009-05-14 G3 Enterprises Modified barrier layers in liners for container closures, capable of providing varible, controlled oxygen ingress
WO2009065005A1 (en) 2007-11-14 2009-05-22 Stratatech Corporation Cold storage of organotypically cultured skin equivalents for clinical applications
US9143569B2 (en) 2008-02-21 2015-09-22 Dexcom, Inc. Systems and methods for processing, transmitting and displaying sensor data
US8583204B2 (en) 2008-03-28 2013-11-12 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US11730407B2 (en) 2008-03-28 2023-08-22 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8682408B2 (en) 2008-03-28 2014-03-25 Dexcom, Inc. Polymer membranes for continuous analyte sensors
EP2106784B1 (en) * 2008-04-03 2015-04-22 Rohm and Haas Company Hair styling composition
US9382514B2 (en) * 2008-06-20 2016-07-05 Escape Therapeutics, Inc. Compositions comprising mesenchymal stem cell-derived fibroblasts
CN102076365B (zh) * 2008-06-20 2014-07-30 泰国研究基金会 生产人造皮肤的方法和系统
TW201010747A (en) * 2008-09-02 2010-03-16 Univ Nat Taiwan Porous material duct and method of fabricating the same
WO2010052584A2 (en) * 2008-11-07 2010-05-14 Sofradim Production Medical device including a bacterial cellulose sheet, perforated or microperforated as a mesh
CA2741519C (en) 2008-11-07 2017-03-21 Sofradim Production Composite mesh including a 3d mesh and a non porous film of oxidized cellulose from bacterial cellulose origin
JP5715962B2 (ja) 2009-01-30 2015-05-13 バイヤースドルフ・アクチエンゲゼルシヤフトＢｅｉｅｒｓｄｏｒｆ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ コラーゲン、キトサン、グリコシルアミノグリカンおよび細胞増殖促進ペプチドおよび／または細胞複合体よりなる、化粧品または皮膚科学的調製物
KR101177752B1 (ko) 2009-04-24 2012-08-28 영도산업 주식회사 스톱퍼를 구비한 실린더 밸브 및 이를 이용한 실린더 밸브 시스템
US8501476B2 (en) * 2009-10-07 2013-08-06 Brown University Assays and methods for fusing cell aggregates to form proto-tissues
IT1398807B1 (it) * 2009-10-29 2013-03-18 Marzaro Metodo di preparazione di un tessuto organico a-cellulare di origine umana o animale per la rivitalizzazione
EP2539438A1 (en) 2010-02-23 2013-01-02 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for preparing human melanocytes from human pluripotent stem cells
US20140080096A1 (en) * 2010-09-13 2014-03-20 BioEconeer, Inc. Guided Tissue Regeneration Membrane
US20120065741A1 (en) * 2010-09-13 2012-03-15 Chao-Fu Chang Guided tissue regeneration membrane
EP4324399A3 (en) 2011-04-15 2024-05-15 DexCom, Inc. Advanced analyte sensor calibration and error detection
US9243278B2 (en) 2011-09-22 2016-01-26 Brown University Mechanotransduction by the synergistic action of heterotypic cell interactions
US9468680B2 (en) 2011-09-22 2016-10-18 Brown University Differential effects of drugs on transport in a multi-layer 3D spheroid model
TWI590843B (zh) 2011-12-28 2017-07-11 信迪思有限公司 膜及其製造方法
ES2943709T3 (es) 2012-04-06 2023-06-15 Merlin Md Pte Ltd Dispositivos para tratar un aneurisma
CN102697600A (zh) * 2012-05-19 2012-10-03 江苏百得医疗器械有限公司 医用可吸收防粘连薄膜
JP2015518843A (ja) 2012-05-25 2015-07-06 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 創傷、例えば、糖尿病性創傷の処置における、ｄｐｐ−４阻害剤と組み合わせてもよい生物活性物質としてのケラチン生成細胞の使用
WO2014160000A1 (en) 2013-03-13 2014-10-02 Stratatech Corporation Cryopreservation of viable human skin substitutes
WO2014204708A1 (en) 2013-06-21 2014-12-24 DePuy Synthes Products, LLC Films and methods of manufacture
CN103394122B (zh) * 2013-08-08 2014-10-29 中国科学技术大学 一种人工皮肤及其制备方法和应用
ITMI20131904A1 (it) * 2013-11-18 2015-05-19 Antonio Sambusseti Dispositivo per la ricostruzione di cute
US10328178B2 (en) 2014-05-30 2019-06-25 Sofradim Production Implant comprising oxidized cellulose and method for preparing such an implant
USD786509S1 (en) * 2014-08-28 2017-05-09 3M Innovative Properties Company Welding helmet having a button
EP4046667A1 (en) 2017-03-06 2022-08-24 Tei Biosciences, Inc. Perforated tissue graft
US11943876B2 (en) 2017-10-24 2024-03-26 Dexcom, Inc. Pre-connected analyte sensors
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
JP7290302B2 (ja) * 2018-10-26 2023-06-13 国立研究開発法人農業・食品産業技術総合研究機構 ハイドロゲル膜及びその使用
AU2020353695A1 (en) * 2019-09-27 2022-03-31 Stratatech Corporation Methods for treating acute wounds and improving outcomes
US12059509B1 (en) 2020-05-05 2024-08-13 Integra Lifesciences Corporation Method and matrix for tissue regeneration
EP4001296A1 (de) 2020-11-20 2022-05-25 Eberhard Karls Universität Tübingen Neue zyklische verbindungen, verfahren zu deren herstellung und die verwendung dieser zyklischen verbindungen in kosmetischen zubereitungen

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2671444A (en) * 1951-12-08 1954-03-09 Jr Benjamin F Pease Nonmetallic mesh surgical insert for hernia repair
NL8001236A (nl) * 1980-02-29 1981-10-01 Doornes Transmissie Bv Transmissie, voorzien van een traploos variabele drijfriemoverbrenging.
SE444640B (sv) * 1980-08-28 1986-04-28 Bergentz Sven Erik I djur eller menniska implanterbar kerlprotes samt sett for dess framstellning
US4553272A (en) * 1981-02-26 1985-11-19 University Of Pittsburgh Regeneration of living tissues by growth of isolated cells in porous implant and product thereof
US4604346A (en) * 1984-10-09 1986-08-05 Massachusetts Institute Of Technology Skin-equivalent prepared by the use of punch biopsy
EP0183184A1 (en) * 1984-11-30 1986-06-04 Ppg Industries, Inc. Method of cultivating cellular biomaterial and glass fibers with cellular biomaterial or biomaterial
US4765985A (en) * 1985-03-05 1988-08-23 Ciba-Geigy Corporation Devices and methods for treating memory impairment
IL75554A (en) * 1985-06-18 1993-01-14 Yeda Res & Dev Matrix for cell cultivation in vitro
US4851521A (en) * 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
DE3539270A1 (de) * 1985-11-06 1987-05-07 Rolf Prof Dr Med Hettich Folien-spannrahmen fuer mischtransplantat
US5032508A (en) * 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
JPS62246371A (ja) * 1986-04-19 1987-10-27 株式会社　高研 人工皮膚及びその製造方法
DE3878909T2 (de) 1987-04-28 1993-08-19 Univ California Vorrichtung und verfahren zur herstellung eines komposithautersatzes.
FR2616318A1 (fr) * 1987-06-15 1988-12-16 Centre Nat Rech Scient Peau artificielle et son procede de preparation
US5015584A (en) * 1987-10-14 1991-05-14 Board Of Regents, The University Of Texas System Epidermal graft system
US5122470A (en) * 1988-07-05 1992-06-16 Banes Albert J Floating cell culture device and method
NL8801741A (nl) * 1988-07-08 1990-02-01 Utermoehlen Nv Kunsthuid.
DE3830481A1 (de) * 1988-09-08 1990-03-22 Ethicon Gmbh Schlauchfoermiges implantat, sowie verfahren zu dessen herstellung
JPH0662678B2 (ja) * 1988-11-28 1994-08-17 電気化学工業株式会社 ヒアルロン酸固定化蛋白質及びその製造方法
EP0402718B1 (en) * 1989-06-03 1994-11-02 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Control of cell arrangement

Also Published As

Publication number Publication date
EP0462426A1 (en) 1991-12-27
NO303562B1 (no) 1998-08-03
US5326356A (en) 1994-07-05
BR9102225A (pt) 1992-01-07
UY23231A1 (es) 1991-10-28
IT9020513A0 (fi) 1990-06-01
AU637235B2 (en) 1993-05-20
DE69127235D1 (de) 1997-09-18
AR244354A1 (es) 1993-10-29
DK0462426T3 (da) 1998-02-23
CA2043527C (en) 2003-12-16
CA2043527A1 (en) 1991-12-02
HU215534B (hu) 1999-01-28
HU911834D0 (en) 1991-12-30
GR3025075T3 (en) 1998-01-30
US5658331A (en) 1997-08-19
FI912591A (fi) 1991-12-02
PT97832A (pt) 1992-02-28
US5650164A (en) 1997-07-22
HUT60514A (en) 1992-09-28
KR100195574B1 (ko) 1999-06-15
DE69127235T2 (de) 1997-12-04
ES2108019T3 (es) 1997-12-16
PT97832B (pt) 1998-10-30
JP3202257B2 (ja) 2001-08-27
AU7806691A (en) 1991-12-05
TW208652B (fi) 1993-07-01
SG52545A1 (en) 1998-09-28
NO912058D0 (no) 1991-05-29
IT1248934B (it) 1995-02-11
ZA914098B (en) 1992-03-25
ATE156689T1 (de) 1997-08-15
EP0462426B1 (en) 1997-08-13
FI912591A0 (fi) 1991-05-30
FI108918B (fi) 2002-04-30
IL98255A0 (en) 1992-06-21
JPH04231061A (ja) 1992-08-19
NO912058L (no) 1991-12-02
IE911825A1 (en) 1991-12-04
IT9020513A1 (it) 1991-12-01

Similar Documents

Publication Publication Date Title
ZA914098B (en) Biocompatible perforated membranes,processes for their preparation,their use as a support in the in vitro growth of epithelial cells,the artificial skin obtained in this manner,and its use in skin grafts
WO1998026732A8 (en) Stent combination
IT8667924A0 (it) Protesi in materiale polimerico con rivestimento di carbonio biocompatibile
WO1994007432A3 (en) Porous vascular implants
ES476173A1 (es) Un procedimiento para la obtencion de un producto de whitlo-ckita
CA2063810A1 (en) Production of vascular endothelial cell growth factor
CA2207751A1 (en) Controlled porosity endovascular implant
CA2238011A1 (en) A biologic material comprising an efficient culture of bone marrow stem cells partially or completely differentiated into connective tissue cells and a three-dimensional biocompatible and biodegradable matrix consisting of a hyaluronic acid derivative
GB2235690B (en) Hydrophilic semi-permeable ptfe membranes and their manufacture
EP0239697A3 (en) Apparatus for growing tissue cultures in vitro
AU5154390A (en) Biocompatible material and prosthesis
CA2117379A1 (en) Multi-Phase Bioerodible Implant/Carrier and Method of Manufacturing and Using Same
AU7937491A (en) Permeable membrane excellent in biocompatibility
IL115728A0 (en) Biomaterial containing epithelial cells and use thereof as a transplant
AU6775596A (en) Perforated artificial skin grafts
CA2250880A1 (en) Implantable agarose-collagen beads containing cells which produce a diffusible biological product, and uses thereof
EP0491851A4 (en) Method for the production of in vitro expanded lymphoid cells for use in adoptive immunotherapy
AU7252391A (en) Device for subcutaneous introduction, in particular for the implantation of artificial hairs
AU3000601A (en) Method for production of a skin graft and the graft produced thereby
EP0495127A4 (en) Artificial blood vessel and production thereof
IL97801A0 (en) Oligonucleotides,methods for in vitro tissue cell culture using the same and cosmetic compositions containing the same
IT8920158A0 (it) Nuovo procedimento per la preparazione in vitro di membrane emostatiche artificiali.
EG18218A (en) Process for the preparation of cellulose film,cellulose film produce thereby artificial skin graft and its use
WO1993008265A3 (fr) Productions d'os et de nacre, a partir de cellules formatrices d'os mises en presence de nacre
Arnst The latest from the labs: human skin

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired