IL83372A - Carbapenem compound in crystalline form and pharmaceutical composition comprising it - Google Patents

Carbapenem compound in crystalline form and pharmaceutical composition comprising it

Info

Publication number
IL83372A
IL83372A IL83372A IL8337287A IL83372A IL 83372 A IL83372 A IL 83372A IL 83372 A IL83372 A IL 83372A IL 8337287 A IL8337287 A IL 8337287A IL 83372 A IL83372 A IL 83372A
Authority
IL
Israel
Prior art keywords
pharmaceutical composition
crystalline form
carbapenem compound
carbapenem
compound
Prior art date
Application number
IL83372A
Other languages
English (en)
Other versions
IL83372A0 (en
Original Assignee
Sumitomo Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharma filed Critical Sumitomo Pharma
Publication of IL83372A0 publication Critical patent/IL83372A0/xx
Publication of IL83372A publication Critical patent/IL83372A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL83372A 1986-07-30 1987-07-29 Carbapenem compound in crystalline form and pharmaceutical composition comprising it IL83372A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP17932186 1986-07-30
JP15776987 1987-06-26

Publications (2)

Publication Number Publication Date
IL83372A0 IL83372A0 (en) 1987-12-31
IL83372A true IL83372A (en) 1992-05-25

Family

ID=26485103

Family Applications (1)

Application Number Title Priority Date Filing Date
IL83372A IL83372A (en) 1986-07-30 1987-07-29 Carbapenem compound in crystalline form and pharmaceutical composition comprising it

Country Status (20)

Country Link
US (1) US4888344A (ko)
EP (1) EP0256377B1 (ko)
JP (1) JP2665767B2 (ko)
AR (1) AR243189A1 (ko)
AU (1) AU596857B2 (ko)
CA (1) CA1322371C (ko)
DE (1) DE3781980T2 (ko)
DK (1) DK172666B1 (ko)
ES (1) ES2052524T3 (ko)
FI (1) FI88037C (ko)
GR (1) GR3006254T3 (ko)
HK (1) HK169595A (ko)
HU (1) HU199473B (ko)
IE (1) IE60588B1 (ko)
IL (1) IL83372A (ko)
LU (1) LU88635I2 (ko)
MX (1) MX173359B (ko)
NO (2) NO165543C (ko)
NZ (1) NZ221224A (ko)
PH (1) PH24710A (ko)

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DE69019610D1 (de) * 1989-07-06 1995-06-29 Banyu Pharma Co Ltd Cyclische Derivate des Amidinylthiocarbapenems.
DE69013131T2 (de) * 1989-12-29 1995-05-24 Banyu Pharma Co Ltd 2-(2-Cyclopropylpyrrolidin-4-ylthio)carbapenemderivate.
TW264475B (ko) * 1991-09-20 1995-12-01 Takeda Pharm Industry Co Ltd
JP2696807B2 (ja) * 1992-08-06 1998-01-14 田辺製薬株式会社 カルバペネム誘導体の製法
GB9503717D0 (en) * 1995-02-24 1995-04-12 Smithkline Beecham Plc Novel compounds
FR2735474B1 (fr) * 1995-06-13 1997-08-08 Roussel Uclaf Chlorhydrate de zilpaterol sous une forme cristallisee particuliere, son procede de preparation et les produits intermediaires mis en oeuvre
RU2178792C2 (ru) * 1997-02-07 2002-01-27 Киото Фармасьютикал Индастриз, Лтд. Производные карбапенема, антибактериальное средство на его основе и его промежуточное соединение
EP1078927B1 (en) 1998-05-01 2006-08-23 Kyoto Pharmaceutical Industries, Ltd. Carbapenem derivatives, utilization thereof and intermediate compounds of the same
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TWI250160B (en) * 1999-07-06 2006-03-01 Sankyo Co Crystalline 1-methylcarbapenem compound
US7041660B2 (en) 1999-07-06 2006-05-09 Sankyo Company, Limited Crystalline 1-methylcarbapenem derivatives
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US8501818B2 (en) * 2005-03-14 2013-08-06 Ceptaris Therapeutics, Inc. Stabilized compositions of alkylating agents and methods of using same
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PL1926732T3 (pl) 2005-09-05 2014-01-31 Ranbaxy Laboratories Ltd Sposób wytwarzania związków karbapenemu
WO2007031858A2 (en) * 2005-09-15 2007-03-22 Orchid Chemicals And Pharmaceuticals Limited An improved process for the preparation of beta-lactam antibiotic
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KR100781821B1 (ko) * 2006-02-16 2007-12-03 문순구 카르바페넴계 화합물의 제조방법
JP5373390B2 (ja) * 2006-03-28 2013-12-18 株式会社カネカ カルバペネム化合物の改良された製造方法
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US20090216010A1 (en) * 2008-02-22 2009-08-27 Wei-Hong Tseng Crystalline carbapenem compound and produced method thereof
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AU2009277936B2 (en) * 2008-07-30 2014-11-27 Sun Pharmaceutical Industries Limited Process for the preparation of carbapenem compounds
WO2010104336A2 (ko) * 2009-03-13 2010-09-16 주식회사 대웅제약 아연 분말을 이용한 메로페넴의 개선된 제조방법
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WO2011141847A1 (en) * 2010-05-10 2011-11-17 Orchid Chemicals And Pharmaceuticals Limited An improved process for the preparation of meropenem
WO2012052978A1 (en) 2010-10-22 2012-04-26 Ranbaxy Laboratories Limited A process for the preparation of pure meropenem trihydrate
CN101962383A (zh) * 2010-11-12 2011-02-02 上海巴迪生物医药科技有限公司 一种美罗培南的合成方法
WO2012081033A2 (en) * 2010-12-06 2012-06-21 Sequent Scientific Limited A process for preparation of imipenem
CN102532140B (zh) * 2010-12-21 2015-03-11 北大方正集团有限公司 一种美罗培南三水合物的制备方法
CN102250096B (zh) * 2011-09-05 2016-04-06 江西华邦药业有限公司 一种美罗培南的制备方法
CN103570718B (zh) * 2012-07-31 2016-06-29 深圳市海滨制药有限公司 一种美罗培南原料药、其制备方法及包含其的药物组合物
CN103570719B (zh) * 2012-07-31 2016-03-02 深圳市海滨制药有限公司 一种美罗培南原料药、其制备方法及包含其的药物组合物
CN103570720B (zh) * 2012-07-31 2016-02-10 新乡海滨药业有限公司 一种美罗培南原料药、其制备方法及包含其的药物组合物
KR101331762B1 (ko) * 2012-12-28 2013-11-20 주식회사 대웅제약 메로페넴의 삼수화물의 제조방법
CN103044429B (zh) * 2013-01-28 2015-04-01 苏州二叶制药有限公司 一种美罗培南的制备方法
ES2835398T3 (es) 2013-02-01 2021-06-22 Ocuphire Pharma Inc Métodos y composiciones para la administración oftálmica diaria de fentolamina para mejorar el rendimiento visual
ES2762153T3 (es) 2013-02-01 2020-05-22 Ocuphire Pharma Inc Soluciones oftálmicas acuosas de fentolamina y usos médicos de las mismas
KR102144777B1 (ko) 2013-06-19 2020-08-18 제이더블유중외제약 주식회사 결정형 메로페넴 삼수화물의 제조방법
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Also Published As

Publication number Publication date
AR243189A1 (es) 1993-07-30
DK399087A (da) 1988-01-31
CA1322371C (en) 1993-09-21
IE871959L (en) 1988-01-30
DE3781980D1 (de) 1992-11-05
GR3006254T3 (ko) 1993-06-21
US4888344A (en) 1989-12-19
DK399087D0 (da) 1987-07-30
HU199473B (en) 1990-02-28
DE3781980T2 (de) 1993-02-18
HK169595A (en) 1995-11-10
PH24710A (en) 1990-10-01
HUT44553A (en) 1988-03-28
FI88037B (fi) 1992-12-15
NZ221224A (en) 1989-10-27
FI873299A0 (fi) 1987-07-29
DK172666B1 (da) 1999-05-10
LU88635I2 (fr) 1995-12-01
AU596857B2 (en) 1990-05-17
NO873205L (no) 1988-02-01
MX173359B (es) 1994-02-23
ES2052524T3 (es) 1994-07-16
FI873299A (fi) 1988-01-31
MX7534A (es) 1993-10-01
FI88037C (fi) 1993-03-25
IE60588B1 (en) 1994-07-27
NO165543C (no) 1991-02-27
NO873205D0 (no) 1987-07-30
NO165543B (no) 1990-11-19
JP2665767B2 (ja) 1997-10-22
EP0256377A1 (en) 1988-02-24
NO1997013I1 (no) 1997-10-17
IL83372A0 (en) 1987-12-31
JPS6434986A (en) 1989-02-06
AU7619687A (en) 1988-03-03
EP0256377B1 (en) 1992-09-30

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