IL83372A - Carbapenem compound in crystalline form and pharmaceutical composition comprising it - Google Patents

Carbapenem compound in crystalline form and pharmaceutical composition comprising it

Info

Publication number
IL83372A
IL83372A IL83372A IL8337287A IL83372A IL 83372 A IL83372 A IL 83372A IL 83372 A IL83372 A IL 83372A IL 8337287 A IL8337287 A IL 8337287A IL 83372 A IL83372 A IL 83372A
Authority
IL
Israel
Prior art keywords
pharmaceutical composition
crystalline form
carbapenem compound
carbapenem
compound
Prior art date
Application number
IL83372A
Other languages
English (en)
Other versions
IL83372A0 (en
Original Assignee
Sumitomo Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharma filed Critical Sumitomo Pharma
Publication of IL83372A0 publication Critical patent/IL83372A0/xx
Publication of IL83372A publication Critical patent/IL83372A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL83372A 1986-07-30 1987-07-29 Carbapenem compound in crystalline form and pharmaceutical composition comprising it IL83372A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP17932186 1986-07-30
JP15776987 1987-06-26

Publications (2)

Publication Number Publication Date
IL83372A0 IL83372A0 (en) 1987-12-31
IL83372A true IL83372A (en) 1992-05-25

Family

ID=26485103

Family Applications (1)

Application Number Title Priority Date Filing Date
IL83372A IL83372A (en) 1986-07-30 1987-07-29 Carbapenem compound in crystalline form and pharmaceutical composition comprising it

Country Status (20)

Country Link
US (1) US4888344A (cs)
EP (1) EP0256377B1 (cs)
JP (1) JP2665767B2 (cs)
AR (1) AR243189A1 (cs)
AU (1) AU596857B2 (cs)
CA (1) CA1322371C (cs)
DE (1) DE3781980T2 (cs)
DK (1) DK172666B1 (cs)
ES (1) ES2052524T3 (cs)
FI (1) FI88037C (cs)
GR (1) GR3006254T3 (cs)
HK (1) HK169595A (cs)
HU (1) HU199473B (cs)
IE (1) IE60588B1 (cs)
IL (1) IL83372A (cs)
LU (1) LU88635I2 (cs)
MX (1) MX173359B (cs)
NO (2) NO165543C (cs)
NZ (1) NZ221224A (cs)
PH (1) PH24710A (cs)

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CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
KR880006244A (ko) * 1986-11-24 1988-07-22 후지사와 도모 기찌 로 3-피롤리디닐티오-1-아자바이스클로[3.2.0]햅트2-엔-2-카르복실산 화합물 및 이의 제조방법
DE69019610D1 (de) * 1989-07-06 1995-06-29 Banyu Pharma Co Ltd Cyclische Derivate des Amidinylthiocarbapenems.
EP0435320B1 (en) * 1989-12-29 1994-10-05 Banyu Pharmaceutical Co., Ltd. 2(2-Cyclopropylpyrrolidin-4-ylthio)-carbapenem derivatives
TW264475B (cs) * 1991-09-20 1995-12-01 Takeda Pharm Industry Co Ltd
JP2696807B2 (ja) * 1992-08-06 1998-01-14 田辺製薬株式会社 カルバペネム誘導体の製法
GB9503717D0 (en) * 1995-02-24 1995-04-12 Smithkline Beecham Plc Novel compounds
FR2735474B1 (fr) * 1995-06-13 1997-08-08 Roussel Uclaf Chlorhydrate de zilpaterol sous une forme cristallisee particuliere, son procede de preparation et les produits intermediaires mis en oeuvre
RU2178792C2 (ru) * 1997-02-07 2002-01-27 Киото Фармасьютикал Индастриз, Лтд. Производные карбапенема, антибактериальное средство на его основе и его промежуточное соединение
AU760386B2 (en) 1998-05-01 2003-05-15 Kyoto Pharmaceutical Industries, Ltd. Carbapenem derivatives, utilization thereof and intermediate compounds of the same
EP1182204B1 (en) * 1999-06-03 2004-04-07 Eisai Co., Ltd. Crystals of carbapenem derivatives and pharmaceutical preparations for injection
TWI250160B (en) * 1999-07-06 2006-03-01 Sankyo Co Crystalline 1-methylcarbapenem compound
US7041660B2 (en) 1999-07-06 2006-05-09 Sankyo Company, Limited Crystalline 1-methylcarbapenem derivatives
PT1280531E (pt) * 2000-05-12 2007-02-28 Novalar Pharmaceuticals Inc Formulação consistindo de mesilato de fentolamina e sua utilização
JP5079190B2 (ja) * 2001-04-27 2012-11-21 大日本住友製薬株式会社 アゼチジノン誘導体およびその製造方法
WO2002094829A1 (fr) * 2001-05-21 2002-11-28 Kyoto Pharmaceutical Industries, Ltd. Compose de carbapenem
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EP1426376A4 (en) * 2001-08-13 2004-12-22 Eisai Co Ltd PROCESS FOR THE PREPARATION OF CARBAPENEM-BASED ANTIBIOTICS
HU230700B1 (hu) * 2001-09-26 2017-09-28 Merck Sharp & Dohme Corp Eljárás karbapenemvegyületek előállítására
JP2005508321A (ja) 2001-09-26 2005-03-31 メルク　エンド　カムパニー　インコーポレーテッド 結晶形態のエルタペネムナトリウム
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EP1541174A4 (en) 2002-09-11 2005-09-14 Michio Ishibashi MEDICINE OR COSMETIC PRODUCT
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JP4547245B2 (ja) * 2004-12-16 2010-09-22 株式会社パーマケム・アジア ペリンドプリルエルブミンのｉ型結晶、及びその製造方法
US8501818B2 (en) * 2005-03-14 2013-08-06 Ceptaris Therapeutics, Inc. Stabilized compositions of alkylating agents and methods of using same
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US20070197781A1 (en) * 2005-07-29 2007-08-23 Neera Tewari Processes for the preparation of carbapenems
PT1926732E (pt) 2005-09-05 2013-12-27 Ranbaxy Lab Ltd Processo para a preparação de compostos de carbapenem
NZ566460A (en) * 2005-09-15 2010-04-30 Orchid Chemicals & Pharm Ltd An improved process for the preparation of beta-lactam antibiotic
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KR100781821B1 (ko) * 2006-02-16 2007-12-03 문순구 카르바페넴계 화합물의 제조방법
JP5373390B2 (ja) * 2006-03-28 2013-12-18 株式会社カネカ カルバペネム化合物の改良された製造方法
KR20090007572A (ko) * 2006-04-28 2009-01-19 카네카 코포레이션 카르바페넴 항생 물질 중간체의 개량된 정석 방법
JPWO2009075309A1 (ja) * 2007-12-12 2011-04-28 大日本住友製薬株式会社 製剤組成物
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US9000150B2 (en) 2010-10-22 2015-04-07 Ranbaxy Laboratories Limited Process for the preparation of pure meropenem trihydrate
CN101962383A (zh) * 2010-11-12 2011-02-02 上海巴迪生物医药科技有限公司 一种美罗培南的合成方法
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CN102532140B (zh) * 2010-12-21 2015-03-11 北大方正集团有限公司 一种美罗培南三水合物的制备方法
CN102250096B (zh) * 2011-09-05 2016-04-06 江西华邦药业有限公司 一种美罗培南的制备方法
CN103570720B (zh) * 2012-07-31 2016-02-10 新乡海滨药业有限公司 一种美罗培南原料药、其制备方法及包含其的药物组合物
CN103570719B (zh) * 2012-07-31 2016-03-02 深圳市海滨制药有限公司 一种美罗培南原料药、其制备方法及包含其的药物组合物
CN103570718B (zh) * 2012-07-31 2016-06-29 深圳市海滨制药有限公司 一种美罗培南原料药、其制备方法及包含其的药物组合物
KR101331762B1 (ko) * 2012-12-28 2013-11-20 주식회사 대웅제약 메로페넴의 삼수화물의 제조방법
CN103044429B (zh) * 2013-01-28 2015-04-01 苏州二叶制药有限公司 一种美罗培南的制备方法
CA2899339C (en) 2013-02-01 2021-07-06 Ocularis Pharma, Llc Aqueous ophthalmic solutions of phentolamine and medical uses thereof
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KR102144777B1 (ko) 2013-06-19 2020-08-18 제이더블유중외제약 주식회사 결정형 메로페넴 삼수화물의 제조방법
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Also Published As

Publication number Publication date
HK169595A (en) 1995-11-10
DE3781980D1 (de) 1992-11-05
FI88037C (fi) 1993-03-25
DK399087A (da) 1988-01-31
AU596857B2 (en) 1990-05-17
NO165543C (no) 1991-02-27
NO1997013I1 (no) 1997-10-17
HU199473B (en) 1990-02-28
IL83372A0 (en) 1987-12-31
JPS6434986A (en) 1989-02-06
DK172666B1 (da) 1999-05-10
ES2052524T3 (es) 1994-07-16
DE3781980T2 (de) 1993-02-18
NZ221224A (en) 1989-10-27
GR3006254T3 (cs) 1993-06-21
EP0256377B1 (en) 1992-09-30
PH24710A (en) 1990-10-01
US4888344A (en) 1989-12-19
LU88635I2 (fr) 1995-12-01
NO873205L (no) 1988-02-01
HUT44553A (en) 1988-03-28
FI88037B (fi) 1992-12-15
FI873299A0 (fi) 1987-07-29
EP0256377A1 (en) 1988-02-24
JP2665767B2 (ja) 1997-10-22
IE60588B1 (en) 1994-07-27
MX7534A (es) 1993-10-01
MX173359B (es) 1994-02-23
FI873299L (fi) 1988-01-31
CA1322371C (en) 1993-09-21
NO873205D0 (no) 1987-07-30
DK399087D0 (da) 1987-07-30
IE871959L (en) 1988-01-30
NO165543B (no) 1990-11-19
AU7619687A (en) 1988-03-03
AR243189A1 (es) 1993-07-30

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