IL77577A - Cyclic imide derivatives of 2-(-4-butylpiperazin-1-yl)pyridines,their preparation and pharmaceutical compositions containing them - Google Patents

Cyclic imide derivatives of 2-(-4-butylpiperazin-1-yl)pyridines,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL77577A
IL77577A IL77577A IL7757786A IL77577A IL 77577 A IL77577 A IL 77577A IL 77577 A IL77577 A IL 77577A IL 7757786 A IL7757786 A IL 7757786A IL 77577 A IL77577 A IL 77577A
Authority
IL
Israel
Prior art keywords
butylpiperazin
pyridines
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL77577A
Other languages
English (en)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IL77577A publication Critical patent/IL77577A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL77577A 1985-01-16 1986-01-13 Cyclic imide derivatives of 2-(-4-butylpiperazin-1-yl)pyridines,their preparation and pharmaceutical compositions containing them IL77577A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/691,952 US4619930A (en) 1985-01-16 1985-01-16 Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use

Publications (1)

Publication Number Publication Date
IL77577A true IL77577A (en) 1990-02-09

Family

ID=24778661

Family Applications (1)

Application Number Title Priority Date Filing Date
IL77577A IL77577A (en) 1985-01-16 1986-01-13 Cyclic imide derivatives of 2-(-4-butylpiperazin-1-yl)pyridines,their preparation and pharmaceutical compositions containing them

Country Status (29)

Country Link
US (1) US4619930A (de)
JP (1) JPH0780873B2 (de)
KR (1) KR900000366B1 (de)
CN (1) CN1016691B (de)
AT (1) AT391698B (de)
AU (1) AU591473B2 (de)
BE (1) BE904047A (de)
CA (1) CA1284325C (de)
CH (1) CH666269A5 (de)
DE (1) DE3601143C2 (de)
DK (1) DK19286A (de)
EG (1) EG17759A (de)
ES (2) ES8705869A1 (de)
FI (1) FI90077C (de)
FR (1) FR2580282B1 (de)
GB (1) GB2191772B (de)
HU (1) HU198202B (de)
IE (1) IE58866B1 (de)
IL (1) IL77577A (de)
IT (1) IT1214497B (de)
LU (1) LU86248A1 (de)
NL (1) NL8600071A (de)
NZ (1) NZ214790A (de)
OA (1) OA08187A (de)
PT (1) PT81843B (de)
SE (1) SE466310B (de)
SU (1) SU1521282A3 (de)
YU (1) YU45757B (de)
ZA (1) ZA859692B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4677104A (en) * 1985-05-06 1987-06-30 Bristol-Myers Company Antipsychotic fused-ring pyridinylpiperazine derivatives
US4812567A (en) * 1985-10-16 1989-03-14 American Home Products Corporation Polycyclic spiroimides with psychotropic activity
MX174210B (es) * 1987-02-17 1994-04-28 Pfizer Procedimiento para la preparacion de compuestos arilpiperazinil-alquilenfenil-p-heterociclicos
US4748240A (en) * 1987-04-03 1988-05-31 American Home Products Corporation Psychotropic bicyclic imides
DE3875073T2 (de) * 1987-11-20 1993-03-11 Hoechst Roussel Pharma 3-(4(1-substituierte-4-piperazinyl)butyl)-4-thiazolidinone, verfahren zu deren herstellung und ihre anwendung als arzneimittel.
US4880930A (en) * 1987-11-30 1989-11-14 New James S Psychotropic acyclic amide derivatives
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US5116970A (en) * 1988-02-18 1992-05-26 New James S Psychotropic heterobicycloalkylpiperazine derivatives: 2. fused pyridazinones
ES2084763T3 (es) * 1990-10-23 1996-05-16 Akzo Nobel Nv 4-(4- o 6-(2-trifluormetil piridinil))1-piperazinilalquilo lactamas sustituidas.
EP2919788A4 (de) 2012-11-14 2016-05-25 Univ Johns Hopkins Verfahren und zusammensetzungen zur behandlung von schizophrenie
CN104230915B (zh) * 2014-08-29 2016-08-17 南京大学 含噻唑烷二酮的苯基哌嗪衍生物及其制备方法与用途
CN104513198A (zh) * 2014-11-29 2015-04-15 南京红太阳生物化学有限责任公司 一种2-氯烟酸的合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US3976776A (en) * 1972-12-06 1976-08-24 Mead Johnson & Company Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
AT330777B (de) * 1973-09-08 1976-07-26 Thomae Gmbh Dr K Verfahren zur herstellung von neuen isochinolinderivaten und deren salzen
US4305944A (en) * 1980-09-08 1981-12-15 Mead Johnson & Company N-[(4-[3-cyano substituted pyridyl]piperazino)alkyl]-azaspirodecanediones
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
US4456756A (en) * 1981-08-03 1984-06-26 Mead Johnson & Company Spirothiazolidinyl piperazine derivatives
DE3135532A1 (de) * 1981-09-08 1983-03-24 NPL po Dvigateli s Vatrešno Gorene, Varna Brennkraftmaschine
US4361565A (en) * 1981-12-28 1982-11-30 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines
JPS5976059A (ja) * 1982-10-21 1984-04-28 Sumitomo Chem Co Ltd 環状イミド誘導体及びその酸付加塩
JPS61238784A (ja) * 1985-04-17 1986-10-24 Sumitomo Seiyaku Kk コハク酸イミド誘導体及びその酸付加塩
DE3529872A1 (de) * 1985-08-21 1987-02-26 Kali Chemie Pharma Gmbh Neue tetraoxoverbindungen

Also Published As

Publication number Publication date
FI90077B (fi) 1993-09-15
FI860136A (fi) 1986-07-17
GB8614686D0 (en) 1986-07-23
AU591473B2 (en) 1989-12-07
OA08187A (fr) 1987-10-30
FI860136A0 (fi) 1986-01-13
JPS61167682A (ja) 1986-07-29
ES557390A0 (es) 1988-02-16
IE58866B1 (en) 1993-11-17
IT8619081A0 (it) 1986-01-15
DK19286D0 (da) 1986-01-15
NL8600071A (nl) 1986-08-18
ATA10086A (de) 1990-05-15
CA1284325C (en) 1991-05-21
AU5229486A (en) 1986-07-24
KR860005808A (ko) 1986-08-13
ZA859692B (en) 1986-07-14
ES8801822A1 (es) 1988-02-16
DE3601143C2 (de) 1994-05-11
BE904047A (fr) 1986-07-15
SU1521282A3 (ru) 1989-11-07
US4619930A (en) 1986-10-28
IE860125L (en) 1986-07-16
GB2191772B (en) 1990-05-23
HUT39743A (en) 1986-10-29
YU4186A (en) 1987-10-31
AT391698B (de) 1990-11-12
PT81843B (pt) 1988-05-27
GB2191772A (en) 1987-12-23
ES8705869A1 (es) 1987-05-16
FR2580282B1 (fr) 1992-10-16
CH666269A5 (de) 1988-07-15
PT81843A (en) 1986-02-01
DK19286A (da) 1986-07-17
JPH0780873B2 (ja) 1995-08-30
SE466310B (sv) 1992-01-27
NZ214790A (en) 1989-04-26
YU45757B (sh) 1992-07-20
CN86100224A (zh) 1986-11-19
ES550829A0 (es) 1987-05-16
KR900000366B1 (ko) 1990-01-25
FI90077C (fi) 1993-12-27
DE3601143A1 (de) 1986-07-17
CN1016691B (zh) 1992-05-20
HU198202B (en) 1989-08-28
EG17759A (en) 1991-03-30
IT1214497B (it) 1990-01-18
LU86248A1 (fr) 1986-08-04
FR2580282A1 (fr) 1986-10-17
SE8600173L (sv) 1986-07-17
SE8600173D0 (sv) 1986-01-15

Similar Documents

Publication Publication Date Title
IL80403A (en) Heterocyclic analogs of mevalonolactone and derivatives thereof,their preparation and pharmaceutical compositions containing them
IL80404A0 (en) Quinoline derivatives,their preparation and pharmaceutical compositions containing them
IL80411A0 (en) Preparation of dibenzopyranol derivatives and pharmaceutical compositions containing them
IL80296A (en) Phenylpyridone derivatives,their preparation and pharmaceutical compositions containing them
IL78581A0 (en) Imidazoquinoline derivatives,their preparation and pharmaceutical compositions containing them
IL82246A0 (en) Quinoline derivatives,their preparation and pharmaceutical compositions containing them
IL79309A (en) (heterocyclic substituted-phenoxy)alkyl-isoxazoles and-furans,their preparation and pharmaceutical compositions containing them
IL78970A0 (en) Heteroaromatic amine derivatives,their preparation and pharmaceutical compositions containing them
IL81611A (en) N-cycloalkano(1,2-b)indole derivatives of aryl-sulfonamides,their preparation and medicaments containing them
IL78942A0 (en) Thiazolidinecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL79401A (en) Distamycin derivatives,their preparation and pharmaceutical compositions containing them
CS357991A3 (en) Benzimidazole derivatives, process of their preparation and pharmaceutical compositions comprising said derivatives
IL80339A0 (en) Benzimidazole derivatives,their preparation and pharmaceutical compositions containing them
IL87089A (en) Derivatives of n-aminobutyl-n- phenylarylamides, their preparation and pharmaceutical compositions containing them
IL77577A (en) Cyclic imide derivatives of 2-(-4-butylpiperazin-1-yl)pyridines,their preparation and pharmaceutical compositions containing them
IL79402A (en) Poly-4-aminopyrrole-2-carboxamido derivatives,their preparation and pharmaceutical compositions containing them
IL84380A0 (en) Dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL82860A0 (en) Dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL79351A0 (en) Diazinylpiperidine derivatives of cyclic amides and imides,their preparation and pharmaceutical compositions containing them
IL80658A0 (en) 6,7,8,9-tetrahydro-10-methyl-pyrido(1,2-a)indol-9-amines and derivatives thereof,their preparation and pharmaceutical compositions containing them
ZA86301B (en) 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL80542A0 (en) Hexahydro-(1)-benzo-,-pyrano-and-thiopyrano(4,3-c)pyridines,their preparation and pharmaceutical compositions containing them
IL80540A0 (en) Dihydropyridine derivatives and pharmaceutical compositions containing them
IL82995A0 (en) Annelated dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL88003A0 (en) Quinoline derivatives,their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
KB Patent renewed
FF Patent granted
KB Patent renewed
KB Patent renewed
EXP Patent expired