IT8619081A0 - Derivati con immidi cicliche di 2-(4-butilpiperazin-1-il)piridine antipsicotici. - Google Patents

Derivati con immidi cicliche di 2-(4-butilpiperazin-1-il)piridine antipsicotici.

Info

Publication number
IT8619081A0
IT8619081A0 IT8619081A IT1908186A IT8619081A0 IT 8619081 A0 IT8619081 A0 IT 8619081A0 IT 8619081 A IT8619081 A IT 8619081A IT 1908186 A IT1908186 A IT 1908186A IT 8619081 A0 IT8619081 A0 IT 8619081A0
Authority
IT
Italy
Prior art keywords
immides
butylpiperazin
antipsychotics
pyridine
cyclic
Prior art date
Application number
IT8619081A
Other languages
English (en)
Other versions
IT1214497B (it
Inventor
James Stewart New
Walter G Lobeck
Josepch P Yevich
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IT8619081A0 publication Critical patent/IT8619081A0/it
Application granted granted Critical
Publication of IT1214497B publication Critical patent/IT1214497B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
IT8619081A 1985-01-16 1986-01-15 Derivati con immidi cicliche di 2-(4-butilpiperazin-1-il)piridine antipsicotici. IT1214497B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/691,952 US4619930A (en) 1985-01-16 1985-01-16 Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use

Publications (2)

Publication Number Publication Date
IT8619081A0 true IT8619081A0 (it) 1986-01-15
IT1214497B IT1214497B (it) 1990-01-18

Family

ID=24778661

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8619081A IT1214497B (it) 1985-01-16 1986-01-15 Derivati con immidi cicliche di 2-(4-butilpiperazin-1-il)piridine antipsicotici.

Country Status (29)

Country Link
US (1) US4619930A (it)
JP (1) JPH0780873B2 (it)
KR (1) KR900000366B1 (it)
CN (1) CN1016691B (it)
AT (1) AT391698B (it)
AU (1) AU591473B2 (it)
BE (1) BE904047A (it)
CA (1) CA1284325C (it)
CH (1) CH666269A5 (it)
DE (1) DE3601143C2 (it)
DK (1) DK19286A (it)
EG (1) EG17759A (it)
ES (2) ES8705869A1 (it)
FI (1) FI90077C (it)
FR (1) FR2580282B1 (it)
GB (1) GB2191772B (it)
HU (1) HU198202B (it)
IE (1) IE58866B1 (it)
IL (1) IL77577A (it)
IT (1) IT1214497B (it)
LU (1) LU86248A1 (it)
NL (1) NL8600071A (it)
NZ (1) NZ214790A (it)
OA (1) OA08187A (it)
PT (1) PT81843B (it)
SE (1) SE466310B (it)
SU (1) SU1521282A3 (it)
YU (1) YU45757B (it)
ZA (1) ZA859692B (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4677104A (en) * 1985-05-06 1987-06-30 Bristol-Myers Company Antipsychotic fused-ring pyridinylpiperazine derivatives
US4812567A (en) * 1985-10-16 1989-03-14 American Home Products Corporation Polycyclic spiroimides with psychotropic activity
MX174210B (es) * 1987-02-17 1994-04-28 Pfizer Procedimiento para la preparacion de compuestos arilpiperazinil-alquilenfenil-p-heterociclicos
US4748240A (en) * 1987-04-03 1988-05-31 American Home Products Corporation Psychotropic bicyclic imides
EP0316723B1 (en) * 1987-11-20 1992-09-30 Hoechst-Roussel Pharmaceuticals Incorporated 3-[4(1-Substituted-4-piperazinyl)butyl]-4-thiazolidinones a process for their preparation and their use as medicaments
US4880930A (en) * 1987-11-30 1989-11-14 New James S Psychotropic acyclic amide derivatives
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US5116970A (en) * 1988-02-18 1992-05-26 New James S Psychotropic heterobicycloalkylpiperazine derivatives: 2. fused pyridazinones
DK0482696T3 (da) * 1990-10-23 1996-05-20 Akzo Nobel Nv 4-(4- eller 6-(trifluormethyl-2-pyridinyl))-1-piperazinylalkyl-substituerede lactamer
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物
CN104230915B (zh) * 2014-08-29 2016-08-17 南京大学 含噻唑烷二酮的苯基哌嗪衍生物及其制备方法与用途
CN104513198A (zh) * 2014-11-29 2015-04-15 南京红太阳生物化学有限责任公司 一种2-氯烟酸的合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US3976776A (en) * 1972-12-06 1976-08-24 Mead Johnson & Company Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
AT330777B (de) * 1973-09-08 1976-07-26 Thomae Gmbh Dr K Verfahren zur herstellung von neuen isochinolinderivaten und deren salzen
US4305944A (en) * 1980-09-08 1981-12-15 Mead Johnson & Company N-[(4-[3-cyano substituted pyridyl]piperazino)alkyl]-azaspirodecanediones
US4456756A (en) * 1981-08-03 1984-06-26 Mead Johnson & Company Spirothiazolidinyl piperazine derivatives
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
DE3135532A1 (de) * 1981-09-08 1983-03-24 NPL po Dvigateli s Vatrešno Gorene, Varna Brennkraftmaschine
US4361565A (en) * 1981-12-28 1982-11-30 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines
JPS5976059A (ja) * 1982-10-21 1984-04-28 Sumitomo Chem Co Ltd 環状イミド誘導体及びその酸付加塩
JPS61238784A (ja) * 1985-04-17 1986-10-24 Sumitomo Seiyaku Kk コハク酸イミド誘導体及びその酸付加塩
DE3529872A1 (de) * 1985-08-21 1987-02-26 Kali Chemie Pharma Gmbh Neue tetraoxoverbindungen

Also Published As

Publication number Publication date
ZA859692B (en) 1986-07-14
JPH0780873B2 (ja) 1995-08-30
HU198202B (en) 1989-08-28
FR2580282A1 (fr) 1986-10-17
AU5229486A (en) 1986-07-24
FI90077C (fi) 1993-12-27
AT391698B (de) 1990-11-12
GB8614686D0 (en) 1986-07-23
ES8801822A1 (es) 1988-02-16
BE904047A (fr) 1986-07-15
FI860136A0 (fi) 1986-01-13
CH666269A5 (de) 1988-07-15
SU1521282A3 (ru) 1989-11-07
ES557390A0 (es) 1988-02-16
DK19286A (da) 1986-07-17
IE860125L (en) 1986-07-16
DK19286D0 (da) 1986-01-15
IL77577A (en) 1990-02-09
GB2191772B (en) 1990-05-23
NZ214790A (en) 1989-04-26
HUT39743A (en) 1986-10-29
OA08187A (fr) 1987-10-30
YU45757B (sh) 1992-07-20
ATA10086A (de) 1990-05-15
SE466310B (sv) 1992-01-27
DE3601143C2 (de) 1994-05-11
DE3601143A1 (de) 1986-07-17
CA1284325C (en) 1991-05-21
FR2580282B1 (fr) 1992-10-16
JPS61167682A (ja) 1986-07-29
US4619930A (en) 1986-10-28
IT1214497B (it) 1990-01-18
PT81843A (en) 1986-02-01
SE8600173D0 (sv) 1986-01-15
EG17759A (en) 1991-03-30
KR860005808A (ko) 1986-08-13
FI90077B (fi) 1993-09-15
CN1016691B (zh) 1992-05-20
PT81843B (pt) 1988-05-27
CN86100224A (zh) 1986-11-19
AU591473B2 (en) 1989-12-07
LU86248A1 (fr) 1986-08-04
NL8600071A (nl) 1986-08-18
SE8600173L (sv) 1986-07-17
ES8705869A1 (es) 1987-05-16
FI860136A (fi) 1986-07-17
IE58866B1 (en) 1993-11-17
KR900000366B1 (ko) 1990-01-25
ES550829A0 (es) 1987-05-16
YU4186A (en) 1987-10-31
GB2191772A (en) 1987-12-23

Similar Documents

Publication Publication Date Title
IT8519773A0 (it) Derivati di 1-fluorofenilbutil-4-(2-pirimidinil) piperazina antipsicotici.
DE3689288D1 (de) Substituierte Pyridinderivate.
IT8619361A0 (it) Androstendione derivati 4-sostituiti e procedimento per laloro preparazione.
IT8521865A0 (it) Derivati di etilendiamminomonoammidi.
IT8619081A0 (it) Derivati con immidi cicliche di 2-(4-butilpiperazin-1-il)piridine antipsicotici.
IT8421273A1 (it) "derivati furanici con attivita' antiulcera"
IT1187714B (it) Tenisoattivi derivati da idrossiacidi bicarbossilici
IT1231238B (it) Derivati ammidinici
IT1203608B (it) Derivati di prolina
IT1231237B (it) Derivati eterociclici
IT8621049A0 (it) Derivati di diazinilpiperidina di ammidi ed immidi cicliche ad azione psicogeriatrica.
IT8619481A0 (it) Derivati eterociclici.
IT8620667A0 (it) Derivati della chinolina
IT8620666A0 (it) Derivati del fenantrene.
DK79986A (da) Pyridinderivater
IT1206736B (it) Complesso con beta-ciclodestrina di derivati della benzensolfonilurea.
IT8619486A0 (it) Derivati eterociclici.
IT8622453A0 (it) Impiego fungicida di derivati della tetraidrobenzotienilurea.
IT8522392A0 (it) Pantotenil derivati.
IT1216787B (it) Immunosoppressori contenenti derivati della chinolina
IT1216999B (it) Derivati di prolina.
IT8619482A0 (it) Derivati eterociclici.
IT8619485A0 (it) Derivati eterociclici.
IT8619487A0 (it) Derivati eterociclici.
IT8619480A0 (it) Derivati eterociclici.

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960129