IL162862A0 - Short-acting sedative hypnotic agents for anesthesia and sedation - Google Patents
Short-acting sedative hypnotic agents for anesthesia and sedationInfo
- Publication number
- IL162862A0 IL162862A0 IL16286203A IL16286203A IL162862A0 IL 162862 A0 IL162862 A0 IL 162862A0 IL 16286203 A IL16286203 A IL 16286203A IL 16286203 A IL16286203 A IL 16286203A IL 162862 A0 IL162862 A0 IL 162862A0
- Authority
- IL
- Israel
- Prior art keywords
- sedation
- anesthesia
- short
- hypnotic agents
- sedative hypnotic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C219/14—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
- C07C235/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35138502P | 2002-01-25 | 2002-01-25 | |
US37921902P | 2002-05-09 | 2002-05-09 | |
PCT/US2003/002227 WO2004037750A2 (en) | 2002-01-25 | 2003-01-24 | Short-acting sedative hypnotic agents for anesthesia and sedation |
Publications (1)
Publication Number | Publication Date |
---|---|
IL162862A0 true IL162862A0 (en) | 2005-11-20 |
Family
ID=32179539
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16286203A IL162862A0 (en) | 2002-01-25 | 2003-01-24 | Short-acting sedative hypnotic agents for anesthesia and sedation |
IL162862A IL162862A (en) | 2002-01-25 | 2004-07-05 | Short-acting sedative hypnotic agents for anesthesia and sedation and pharmaceutical compositions containing them |
IL201639A IL201639A (en) | 2002-01-25 | 2009-10-19 | Intermediates for the preparation of hypnotic sedatives in the short term |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL162862A IL162862A (en) | 2002-01-25 | 2004-07-05 | Short-acting sedative hypnotic agents for anesthesia and sedation and pharmaceutical compositions containing them |
IL201639A IL201639A (en) | 2002-01-25 | 2009-10-19 | Intermediates for the preparation of hypnotic sedatives in the short term |
Country Status (22)
Country | Link |
---|---|
US (4) | US6887866B2 (pt) |
EP (1) | EP1509492B1 (pt) |
KR (2) | KR100951846B1 (pt) |
CN (1) | CN1257152C (pt) |
AT (1) | ATE522498T1 (pt) |
AU (1) | AU2003299453B2 (pt) |
BR (1) | BRPI0307017B1 (pt) |
CA (1) | CA2474262C (pt) |
CY (1) | CY1112487T1 (pt) |
DK (1) | DK1509492T3 (pt) |
ES (1) | ES2371461T3 (pt) |
HK (1) | HK1075039A1 (pt) |
IL (3) | IL162862A0 (pt) |
MX (1) | MXPA04007023A (pt) |
NZ (1) | NZ534012A (pt) |
PL (1) | PL207038B1 (pt) |
PT (1) | PT1509492E (pt) |
RU (1) | RU2315037C2 (pt) |
SI (1) | SI1509492T1 (pt) |
TW (1) | TWI290466B (pt) |
WO (1) | WO2004037750A2 (pt) |
ZA (1) | ZA200405561B (pt) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE522498T1 (de) | 2002-01-25 | 2011-09-15 | Theravance Inc | Sedative hypnotisch wirkende verbindungen mit kurzer wirkungsdauer zur anaesthesie und sedierung |
ES2332514T3 (es) | 2003-07-23 | 2010-02-08 | Theravance, Inc. | Composiciones farmaceuticas de un agente hipnotico sedante de accion corta. |
US8329744B2 (en) * | 2005-11-02 | 2012-12-11 | Relmada Therapeutics, Inc. | Methods of preventing the serotonin syndrome and compositions for use thereof |
US20090082466A1 (en) * | 2006-01-27 | 2009-03-26 | Najib Babul | Abuse Resistant and Extended Release Formulations and Method of Use Thereof |
US9125833B2 (en) * | 2005-11-02 | 2015-09-08 | Relmada Therapeutics, Inc. | Multimodal abuse resistant and extended release opioid formulations |
US20090286832A1 (en) * | 2008-05-15 | 2009-11-19 | Kiichiro Nabeta | Narcotic emulsion formulations for treatment of surgical pain |
US20110020423A1 (en) | 2009-07-22 | 2011-01-27 | Puretech Ventures | Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation |
CN102190580A (zh) * | 2010-03-12 | 2011-09-21 | 重庆欣欣向荣精细化工有限公司 | 乙基香兰素合成中间体3-乙氧基-4-羟基扁桃酸的制备方法 |
WO2011149412A1 (en) * | 2010-05-13 | 2011-12-01 | Astrazeneca Ab | Injectable emulsion of sedative hypnotic agent |
CN102863353A (zh) * | 2012-07-27 | 2013-01-09 | 华中科技大学 | 取代的苯基乙酸酯化合物及其应用 |
CN103450009B (zh) * | 2013-09-02 | 2015-04-22 | 江苏宝众宝达药业有限公司 | 一种对羟基苯乙酸的制备方法 |
CN105272871B (zh) * | 2014-06-20 | 2017-08-22 | 济南蓝丹医药科技有限公司 | 具有提高的药代动力学性能和麻醉性能的苯基乙酸酯类化合物 |
CN104211615B (zh) * | 2014-08-12 | 2017-11-03 | 武汉珈瑜科技有限公司 | 苯基氟取代的苯乙酸酯化合物及其应用 |
CN104262292B (zh) * | 2014-09-08 | 2019-02-22 | 武汉珈瑜科技有限公司 | 苯乙酸酯化合物及其应用 |
CN104622806B (zh) * | 2015-02-04 | 2018-03-16 | 北京蓝丹医药科技有限公司 | 一种丙泮尼地药物组合物及其制备方法 |
CN104887628A (zh) * | 2015-06-02 | 2015-09-09 | 北京蓝丹医药科技有限公司 | 一种稳定的苯基乙酸酯类药物脂肪乳 |
CN104887629A (zh) * | 2015-06-09 | 2015-09-09 | 北京蓝丹医药科技有限公司 | 一种稳定的丙泮尼地脂肪乳 |
IL295341A (en) | 2018-09-28 | 2022-10-01 | Karuna Therapeutics Inc | Compositions and methods for the treatment of diseases improved by the activation of muscarinic receptors |
US20230167045A1 (en) | 2020-04-27 | 2023-06-01 | Symrise Ag | Method for producing esters of homovanillic acid |
Family Cites Families (35)
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US3086976A (en) | 1959-01-23 | 1963-04-23 | Egyt Gyogyszervegyeszeti Gyar | Benzoic acid derivatives and process for producing same |
US3086978A (en) * | 1960-05-06 | 1963-04-23 | Bayer Ag | 3-methoxy-4-carbamidomethoxy-phenylacetic acid esters |
DE1134981B (de) * | 1960-05-06 | 1962-08-23 | Bayer Ag | Verfahren zur Herstellung von N-substituierten 3-Methoxy-4-carbamidomethoxyphenylessigsaeurealkyl- und alkenylestern |
US3088978A (en) * | 1960-09-12 | 1963-05-07 | Walter H Brunner | Catalytic hydrogenation of 2, 4-dinitrophenylamines |
BE624258A (pt) | 1961-10-31 | |||
NL286944A (pt) | 1961-12-20 | |||
CH432494A (de) | 1964-01-10 | 1967-03-31 | Geigy Ag J R | Verfahren zur Herstellung neuer Aryloxyessigsäureamide |
US3510559A (en) | 1964-01-10 | 1970-05-05 | Geigy Chem Corp | 2-alkoxyphenoxy-acetamides as anesthetics agents |
DE1249851B (de) | 1964-02-11 | 1967-09-14 | J R Geigy A G Basel (Schweiz) | Morel Ariesheim (Schweiz) j Verfahren zur Herstellung neuer Phenoxyessigsäure amide |
US3511877A (en) | 1964-02-11 | 1970-05-12 | Geigy Chem Corp | Phenoxyacetic acid diethylamides |
DE1518819B1 (de) | 1965-04-03 | 1969-12-04 | Basf Ag | Loesungsvermittler fuer pharmazeutische Zwecke |
US3484537A (en) * | 1969-03-03 | 1969-12-16 | American Mach & Foundry | Photocontrol enclosure and support |
US4798846A (en) | 1974-03-28 | 1989-01-17 | Imperial Chemical Industries Plc | Pharmaceutical compositions |
GB1571395A (en) | 1976-07-12 | 1980-07-16 | Delmar Chem | Substituted phenyl acetic acid esters |
JPS5699440A (en) | 1980-01-11 | 1981-08-10 | Ube Ind Ltd | Preparation of 3-alkoxy-4-hydroxyphenylacetic acid |
ATE11736T1 (de) | 1980-12-23 | 1985-02-15 | Dr. Franz Koehler Chemie Gmbh | Protektive loesung fuer herz und niere und verfahren zu deren herstellung. |
JPS6038343A (ja) * | 1983-08-11 | 1985-02-27 | Mitsubishi Petrochem Co Ltd | フエニル酢酸誘導体の製造方法 |
DE3339236A1 (de) | 1983-10-28 | 1985-05-09 | Bayer Ag | Arzneimittelzubereitung |
US4918092A (en) * | 1983-12-21 | 1990-04-17 | Merck Frosst Canada, Inc. | Leukotriene antagonists |
IT1204778B (it) | 1986-02-04 | 1989-03-10 | Mazzarella Basilio | Formulazioni farmaceutiche iniettabili di principi attivi ad attivita' anestetica generale |
US5092838A (en) | 1989-11-30 | 1992-03-03 | Baxter International Inc. | Histidine buffered peritoneal dialysis solution |
US4981092A (en) * | 1989-11-17 | 1991-01-01 | R. G. Barry Corporation | Fabric clamping device for embroidery machines |
US5242944A (en) * | 1991-06-20 | 1993-09-07 | Korea Research Institute Of Chemical Technology | Phenylacetamide derivatives and pharmaceutical compositions thereof |
GB9405593D0 (en) | 1994-03-22 | 1994-05-11 | Zeneca Ltd | Pharmaceutical compositions |
US20020173547A1 (en) | 1994-03-22 | 2002-11-21 | Jones Christopher Buchan | Pharmaceuticals compositions |
ZA962214B (en) | 1995-04-10 | 1996-10-07 | Farmarc Nederland Bv | Pharmaceutical composition |
JPH0926544A (ja) * | 1995-07-10 | 1997-01-28 | Nikon Corp | 顕微鏡用中間鏡筒 |
US6281175B1 (en) | 1997-09-23 | 2001-08-28 | Scimed Life Systems, Inc. | Medical emulsion for lubrication and delivery of drugs |
NZ505948A (en) | 1998-02-10 | 2003-10-31 | Sicor Inc | Propofol composition containing sulfite as a preservative to prevent bacterial growth of Staphylococcus, Escherichia, Pseudomonas and Candida |
US6028108A (en) | 1998-10-22 | 2000-02-22 | America Home Products Corporation | Propofol composition comprising pentetate |
US6140373A (en) | 1998-10-23 | 2000-10-31 | Abbott Laboratories | Propofol composition |
US6140374A (en) | 1998-10-23 | 2000-10-31 | Abbott Laboratories | Propofol composition |
US6177477B1 (en) | 1999-03-24 | 2001-01-23 | American Home Products Corporation | Propofol formulation containing TRIS |
US6726919B2 (en) | 2000-06-16 | 2004-04-27 | Rtp Pharma, Inc. | Injectable dispersion of propofol |
ATE522498T1 (de) | 2002-01-25 | 2011-09-15 | Theravance Inc | Sedative hypnotisch wirkende verbindungen mit kurzer wirkungsdauer zur anaesthesie und sedierung |
-
2003
- 2003-01-24 AT AT03799743T patent/ATE522498T1/de active
- 2003-01-24 DK DK03799743.4T patent/DK1509492T3/da active
- 2003-01-24 PL PL373420A patent/PL207038B1/pl unknown
- 2003-01-24 NZ NZ534012A patent/NZ534012A/en not_active IP Right Cessation
- 2003-01-24 CN CNB038026910A patent/CN1257152C/zh not_active Expired - Fee Related
- 2003-01-24 CA CA2474262A patent/CA2474262C/en not_active Expired - Fee Related
- 2003-01-24 KR KR1020087016567A patent/KR100951846B1/ko not_active IP Right Cessation
- 2003-01-24 ES ES03799743T patent/ES2371461T3/es not_active Expired - Lifetime
- 2003-01-24 KR KR1020047011420A patent/KR100925790B1/ko not_active IP Right Cessation
- 2003-01-24 SI SI200332070T patent/SI1509492T1/sl unknown
- 2003-01-24 IL IL16286203A patent/IL162862A0/xx unknown
- 2003-01-24 AU AU2003299453A patent/AU2003299453B2/en not_active Ceased
- 2003-01-24 EP EP03799743A patent/EP1509492B1/en not_active Expired - Lifetime
- 2003-01-24 US US10/350,624 patent/US6887866B2/en not_active Expired - Fee Related
- 2003-01-24 WO PCT/US2003/002227 patent/WO2004037750A2/en active Application Filing
- 2003-01-24 PT PT03799743T patent/PT1509492E/pt unknown
- 2003-01-24 RU RU2004125854/04A patent/RU2315037C2/ru not_active IP Right Cessation
- 2003-01-24 BR BRPI0307017A patent/BRPI0307017B1/pt not_active IP Right Cessation
- 2003-05-27 TW TW092114270A patent/TWI290466B/zh not_active IP Right Cessation
-
2004
- 2004-07-05 IL IL162862A patent/IL162862A/en not_active IP Right Cessation
- 2004-07-13 ZA ZA2004/05561A patent/ZA200405561B/en unknown
- 2004-07-20 MX MXPA04007023A patent/MXPA04007023A/es active IP Right Grant
- 2004-11-03 US US10/980,067 patent/US7015346B2/en not_active Expired - Fee Related
-
2005
- 2005-08-24 HK HK05107428.2A patent/HK1075039A1/xx not_active IP Right Cessation
-
2006
- 2006-01-13 US US11/332,409 patent/US7514425B2/en not_active Expired - Fee Related
-
2009
- 2009-03-10 US US12/400,942 patent/US7939689B2/en not_active Expired - Fee Related
- 2009-10-19 IL IL201639A patent/IL201639A/en not_active IP Right Cessation
-
2011
- 2011-11-07 CY CY20111101067T patent/CY1112487T1/el unknown
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