HK1075039A1 - Short-acting sedative hypnotic agents for anesthesia and sedation - Google Patents
Short-acting sedative hypnotic agents for anesthesia and sedationInfo
- Publication number
- HK1075039A1 HK1075039A1 HK05107428.2A HK05107428A HK1075039A1 HK 1075039 A1 HK1075039 A1 HK 1075039A1 HK 05107428 A HK05107428 A HK 05107428A HK 1075039 A1 HK1075039 A1 HK 1075039A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- sedation
- anesthesia
- short
- hypnotic agents
- sedative hypnotic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C219/14—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
- C07C235/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35138502P | 2002-01-25 | 2002-01-25 | |
| US37921902P | 2002-05-09 | 2002-05-09 | |
| PCT/US2003/002227 WO2004037750A2 (en) | 2002-01-25 | 2003-01-24 | Short-acting sedative hypnotic agents for anesthesia and sedation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1075039A1 true HK1075039A1 (en) | 2005-12-02 |
Family
ID=32179539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK05107428.2A HK1075039A1 (en) | 2002-01-25 | 2005-08-24 | Short-acting sedative hypnotic agents for anesthesia and sedation |
Country Status (22)
| Country | Link |
|---|---|
| US (4) | US6887866B2 (pt) |
| EP (1) | EP1509492B1 (pt) |
| KR (2) | KR100951846B1 (pt) |
| CN (1) | CN1257152C (pt) |
| AT (1) | ATE522498T1 (pt) |
| AU (1) | AU2003299453B2 (pt) |
| BR (1) | BRPI0307017B1 (pt) |
| CA (1) | CA2474262C (pt) |
| CY (1) | CY1112487T1 (pt) |
| DK (1) | DK1509492T3 (pt) |
| ES (1) | ES2371461T3 (pt) |
| HK (1) | HK1075039A1 (pt) |
| IL (3) | IL162862A0 (pt) |
| MX (1) | MXPA04007023A (pt) |
| NZ (1) | NZ534012A (pt) |
| PL (1) | PL207038B1 (pt) |
| PT (1) | PT1509492E (pt) |
| RU (1) | RU2315037C2 (pt) |
| SI (1) | SI1509492T1 (pt) |
| TW (1) | TWI290466B (pt) |
| WO (1) | WO2004037750A2 (pt) |
| ZA (1) | ZA200405561B (pt) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1509492T3 (da) * | 2002-01-25 | 2011-11-28 | Theravance Inc | Sedative hypnotiske midler med kort virkningsvarighed til anæstesi og sedation |
| US7790766B2 (en) * | 2003-07-23 | 2010-09-07 | Theravance, Inc. | Pharmaceutical compositions of short-acting sedative hypnotic agent |
| US8329744B2 (en) * | 2005-11-02 | 2012-12-11 | Relmada Therapeutics, Inc. | Methods of preventing the serotonin syndrome and compositions for use thereof |
| US9125833B2 (en) * | 2005-11-02 | 2015-09-08 | Relmada Therapeutics, Inc. | Multimodal abuse resistant and extended release opioid formulations |
| WO2007087452A2 (en) * | 2006-01-27 | 2007-08-02 | Theraquest Biosciences, Llc | Abuse resistant and extended release formulations and method of use thereof |
| US20090286832A1 (en) * | 2008-05-15 | 2009-11-19 | Kiichiro Nabeta | Narcotic emulsion formulations for treatment of surgical pain |
| ES2742728T3 (es) | 2009-07-22 | 2020-02-17 | PureTech Health LLC | Composiciones para el tratamiento de trastornos mejorados por la activación del receptor muscarínico |
| CN102190580A (zh) * | 2010-03-12 | 2011-09-21 | 重庆欣欣向荣精细化工有限公司 | 乙基香兰素合成中间体3-乙氧基-4-羟基扁桃酸的制备方法 |
| US20130236501A1 (en) * | 2010-05-13 | 2013-09-12 | Astrazeneca Ab | Injectable Emulsion of Sedative Hypnotic Agent |
| CN102863353A (zh) * | 2012-07-27 | 2013-01-09 | 华中科技大学 | 取代的苯基乙酸酯化合物及其应用 |
| CN103450009B (zh) * | 2013-09-02 | 2015-04-22 | 江苏宝众宝达药业有限公司 | 一种对羟基苯乙酸的制备方法 |
| CN105272871B (zh) * | 2014-06-20 | 2017-08-22 | 济南蓝丹医药科技有限公司 | 具有提高的药代动力学性能和麻醉性能的苯基乙酸酯类化合物 |
| CN104211615B (zh) * | 2014-08-12 | 2017-11-03 | 武汉珈瑜科技有限公司 | 苯基氟取代的苯乙酸酯化合物及其应用 |
| CN104262292B (zh) * | 2014-09-08 | 2019-02-22 | 武汉珈瑜科技有限公司 | 苯乙酸酯化合物及其应用 |
| CN104622806B (zh) * | 2015-02-04 | 2018-03-16 | 北京蓝丹医药科技有限公司 | 一种丙泮尼地药物组合物及其制备方法 |
| CN104887628A (zh) * | 2015-06-02 | 2015-09-09 | 北京蓝丹医药科技有限公司 | 一种稳定的苯基乙酸酯类药物脂肪乳 |
| CN104887629A (zh) * | 2015-06-09 | 2015-09-09 | 北京蓝丹医药科技有限公司 | 一种稳定的丙泮尼地脂肪乳 |
| AU2019346626B2 (en) | 2018-09-28 | 2022-06-02 | Karuna Therapeutics, Inc. | Compositions and methods for treating disorders ameliorated by muscarinic receptor activation |
| US20230167045A1 (en) | 2020-04-27 | 2023-06-01 | Symrise Ag | Method for producing esters of homovanillic acid |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3086976A (en) | 1959-01-23 | 1963-04-23 | Egyt Gyogyszervegyeszeti Gyar | Benzoic acid derivatives and process for producing same |
| DE1134981B (de) | 1960-05-06 | 1962-08-23 | Bayer Ag | Verfahren zur Herstellung von N-substituierten 3-Methoxy-4-carbamidomethoxyphenylessigsaeurealkyl- und alkenylestern |
| US3086978A (en) * | 1960-05-06 | 1963-04-23 | Bayer Ag | 3-methoxy-4-carbamidomethoxy-phenylacetic acid esters |
| US3088978A (en) * | 1960-09-12 | 1963-05-07 | Walter H Brunner | Catalytic hydrogenation of 2, 4-dinitrophenylamines |
| NL284933A (pt) | 1961-10-31 | |||
| NL286944A (pt) | 1961-12-20 | |||
| CH432494A (de) | 1964-01-10 | 1967-03-31 | Geigy Ag J R | Verfahren zur Herstellung neuer Aryloxyessigsäureamide |
| US3510559A (en) * | 1964-01-10 | 1970-05-05 | Geigy Chem Corp | 2-alkoxyphenoxy-acetamides as anesthetics agents |
| US3511877A (en) * | 1964-02-11 | 1970-05-12 | Geigy Chem Corp | Phenoxyacetic acid diethylamides |
| DE1249851B (de) * | 1964-02-11 | 1967-09-14 | J R Geigy A G Basel (Schweiz) | Morel Ariesheim (Schweiz) j Verfahren zur Herstellung neuer Phenoxyessigsäure amide |
| DE1518819B1 (de) | 1965-04-03 | 1969-12-04 | Basf Ag | Loesungsvermittler fuer pharmazeutische Zwecke |
| US3484537A (en) | 1969-03-03 | 1969-12-16 | American Mach & Foundry | Photocontrol enclosure and support |
| US4798846A (en) | 1974-03-28 | 1989-01-17 | Imperial Chemical Industries Plc | Pharmaceutical compositions |
| GB1571395A (en) | 1976-07-12 | 1980-07-16 | Delmar Chem | Substituted phenyl acetic acid esters |
| JPS5699440A (en) * | 1980-01-11 | 1981-08-10 | Ube Ind Ltd | Preparation of 3-alkoxy-4-hydroxyphenylacetic acid |
| EP0054635B1 (de) | 1980-12-23 | 1985-02-13 | Dr. Franz Köhler Chemie GmbH | Protektive Lösung für Herz und Niere und Verfahren zu deren Herstellung |
| JPS6038343A (ja) * | 1983-08-11 | 1985-02-27 | Mitsubishi Petrochem Co Ltd | フエニル酢酸誘導体の製造方法 |
| DE3339236A1 (de) * | 1983-10-28 | 1985-05-09 | Bayer Ag | Arzneimittelzubereitung |
| US4918092A (en) * | 1983-12-21 | 1990-04-17 | Merck Frosst Canada, Inc. | Leukotriene antagonists |
| IT1204778B (it) | 1986-02-04 | 1989-03-10 | Mazzarella Basilio | Formulazioni farmaceutiche iniettabili di principi attivi ad attivita' anestetica generale |
| US5092838A (en) | 1989-11-30 | 1992-03-03 | Baxter International Inc. | Histidine buffered peritoneal dialysis solution |
| US4981092A (en) * | 1989-11-17 | 1991-01-01 | R. G. Barry Corporation | Fabric clamping device for embroidery machines |
| US5242944A (en) * | 1991-06-20 | 1993-09-07 | Korea Research Institute Of Chemical Technology | Phenylacetamide derivatives and pharmaceutical compositions thereof |
| US20020173547A1 (en) | 1994-03-22 | 2002-11-21 | Jones Christopher Buchan | Pharmaceuticals compositions |
| GB9405593D0 (en) | 1994-03-22 | 1994-05-11 | Zeneca Ltd | Pharmaceutical compositions |
| ZA962214B (en) | 1995-04-10 | 1996-10-07 | Farmarc Nederland Bv | Pharmaceutical composition |
| JPH0926544A (ja) * | 1995-07-10 | 1997-01-28 | Nikon Corp | 顕微鏡用中間鏡筒 |
| US6281175B1 (en) | 1997-09-23 | 2001-08-28 | Scimed Life Systems, Inc. | Medical emulsion for lubrication and delivery of drugs |
| PT1052975E (pt) | 1998-02-10 | 2007-10-29 | Sicor Inc | Composição de propofol que contém sulfito |
| US6028108A (en) | 1998-10-22 | 2000-02-22 | America Home Products Corporation | Propofol composition comprising pentetate |
| US6140374A (en) | 1998-10-23 | 2000-10-31 | Abbott Laboratories | Propofol composition |
| US6140373A (en) | 1998-10-23 | 2000-10-31 | Abbott Laboratories | Propofol composition |
| US6177477B1 (en) | 1999-03-24 | 2001-01-23 | American Home Products Corporation | Propofol formulation containing TRIS |
| WO2001097779A2 (en) | 2000-06-16 | 2001-12-27 | Rtp Pharma Inc. | Improved injectable dispersions of propofol |
| DK1509492T3 (da) | 2002-01-25 | 2011-11-28 | Theravance Inc | Sedative hypnotiske midler med kort virkningsvarighed til anæstesi og sedation |
-
2003
- 2003-01-24 DK DK03799743.4T patent/DK1509492T3/da active
- 2003-01-24 PT PT03799743T patent/PT1509492E/pt unknown
- 2003-01-24 WO PCT/US2003/002227 patent/WO2004037750A2/en active Application Filing
- 2003-01-24 US US10/350,624 patent/US6887866B2/en not_active Expired - Fee Related
- 2003-01-24 AT AT03799743T patent/ATE522498T1/de active
- 2003-01-24 CN CNB038026910A patent/CN1257152C/zh not_active Expired - Fee Related
- 2003-01-24 KR KR1020087016567A patent/KR100951846B1/ko not_active IP Right Cessation
- 2003-01-24 ES ES03799743T patent/ES2371461T3/es not_active Expired - Lifetime
- 2003-01-24 CA CA2474262A patent/CA2474262C/en not_active Expired - Fee Related
- 2003-01-24 NZ NZ534012A patent/NZ534012A/en not_active IP Right Cessation
- 2003-01-24 KR KR1020047011420A patent/KR100925790B1/ko not_active IP Right Cessation
- 2003-01-24 IL IL16286203A patent/IL162862A0/xx unknown
- 2003-01-24 SI SI200332070T patent/SI1509492T1/sl unknown
- 2003-01-24 PL PL373420A patent/PL207038B1/pl unknown
- 2003-01-24 AU AU2003299453A patent/AU2003299453B2/en not_active Ceased
- 2003-01-24 RU RU2004125854/04A patent/RU2315037C2/ru not_active IP Right Cessation
- 2003-01-24 EP EP03799743A patent/EP1509492B1/en not_active Expired - Lifetime
- 2003-01-24 BR BRPI0307017A patent/BRPI0307017B1/pt not_active IP Right Cessation
- 2003-05-27 TW TW092114270A patent/TWI290466B/zh not_active IP Right Cessation
-
2004
- 2004-07-05 IL IL162862A patent/IL162862A/en not_active IP Right Cessation
- 2004-07-13 ZA ZA2004/05561A patent/ZA200405561B/en unknown
- 2004-07-20 MX MXPA04007023A patent/MXPA04007023A/es active IP Right Grant
- 2004-11-03 US US10/980,067 patent/US7015346B2/en not_active Expired - Fee Related
-
2005
- 2005-08-24 HK HK05107428.2A patent/HK1075039A1/xx not_active IP Right Cessation
-
2006
- 2006-01-13 US US11/332,409 patent/US7514425B2/en not_active Expired - Fee Related
-
2009
- 2009-03-10 US US12/400,942 patent/US7939689B2/en not_active Expired - Fee Related
- 2009-10-19 IL IL201639A patent/IL201639A/en not_active IP Right Cessation
-
2011
- 2011-11-07 CY CY20111101067T patent/CY1112487T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20180124 |