IL160739A0 - Oxazolidinone and/or isoxazoline as antibacterial agents - Google Patents
Oxazolidinone and/or isoxazoline as antibacterial agentsInfo
- Publication number
- IL160739A0 IL160739A0 IL16073902A IL16073902A IL160739A0 IL 160739 A0 IL160739 A0 IL 160739A0 IL 16073902 A IL16073902 A IL 16073902A IL 16073902 A IL16073902 A IL 16073902A IL 160739 A0 IL160739 A0 IL 160739A0
- Authority
- IL
- Israel
- Prior art keywords
- isoxazoline
- oxazolidinone
- antibacterial agents
- antibacterial
- agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0121942A GB0121942D0 (en) | 2001-09-11 | 2001-09-11 | Chemical compounds |
GB0215420A GB0215420D0 (en) | 2002-07-04 | 2002-07-04 | Chemical compounds |
PCT/GB2002/004120 WO2003022824A1 (en) | 2001-09-11 | 2002-09-09 | Oxazolidinone and/or isoxazoline as antibacterial agents |
Publications (1)
Publication Number | Publication Date |
---|---|
IL160739A0 true IL160739A0 (en) | 2004-08-31 |
Family
ID=26246531
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16073902A IL160739A0 (en) | 2001-09-11 | 2002-09-09 | Oxazolidinone and/or isoxazoline as antibacterial agents |
Country Status (26)
Country | Link |
---|---|
US (2) | US7396847B2 (es) |
EP (1) | EP1427711B1 (es) |
JP (1) | JP2005507386A (es) |
KR (1) | KR20040044886A (es) |
CN (1) | CN1639136A (es) |
AR (1) | AR036778A1 (es) |
AT (1) | ATE299502T1 (es) |
AU (1) | AU2002329393B2 (es) |
BR (1) | BR0212458A (es) |
CA (1) | CA2459766A1 (es) |
CO (1) | CO5560609A2 (es) |
DE (1) | DE60205030T2 (es) |
DK (1) | DK1427711T3 (es) |
ES (1) | ES2244802T3 (es) |
HK (1) | HK1065789A1 (es) |
HU (1) | HUP0401005A3 (es) |
IL (1) | IL160739A0 (es) |
IS (1) | IS7175A (es) |
MX (1) | MXPA04002303A (es) |
NO (1) | NO327010B1 (es) |
NZ (1) | NZ531621A (es) |
PL (1) | PL369183A1 (es) |
PT (1) | PT1427711E (es) |
RU (1) | RU2004111285A (es) |
SI (1) | SI1427711T1 (es) |
WO (1) | WO2003022824A1 (es) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6667299B1 (en) * | 2000-03-16 | 2003-12-23 | Hollis-Eden Pharmaceuticals, Inc. | Pharmaceutical compositions and treatment methods |
EP1443930A1 (en) | 2001-10-25 | 2004-08-11 | AstraZeneca AB | Isoxazoline derivatives useful as antimicrobials |
IL163688A0 (en) | 2002-02-28 | 2005-12-18 | Astrazeneca Ab | 3-Cyclyl-5-(nitrogen-containing 5-membered ring)methyl-oxazolidinone derivatives and theiruse as antibacterial agents |
CA2477379A1 (en) | 2002-02-28 | 2003-09-04 | Astrazeneca Ab | Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them |
IL164487A0 (en) * | 2002-04-25 | 2005-12-18 | Basf Ag | 3-Heteroaryl substituted 5-methyloxymethyl isoxazolines used as herbicides |
US7091196B2 (en) | 2002-09-26 | 2006-08-15 | Rib-X Pharmaceuticals, Inc. | Bifunctional heterocyclic compounds and methods of making and using same |
US20060116400A1 (en) * | 2002-11-28 | 2006-06-01 | Astrazeneca Ab | Oxazolidinone and/or isoxazoline derivatives as antibacterial agents |
GB0227701D0 (en) * | 2002-11-28 | 2003-01-08 | Astrazeneca Ab | Chemical compounds |
EP1581524A2 (en) * | 2002-11-28 | 2005-10-05 | AstraZeneca AB | Oxazolidinones as antibacterial agents |
GB0229521D0 (en) * | 2002-12-19 | 2003-01-22 | Astrazeneca Ab | Chemical compounds |
GB0229522D0 (en) * | 2002-12-19 | 2003-01-22 | Astrazeneca Ab | Chemical compounds |
GB0229526D0 (en) * | 2002-12-19 | 2003-01-22 | Astrazeneca Ab | Chemical compounds |
TW200500360A (en) * | 2003-03-01 | 2005-01-01 | Astrazeneca Ab | Hydroxymethyl compounds |
GB0304723D0 (en) * | 2003-03-01 | 2003-04-02 | Astrazeneca Ab | Chemical compounds |
EP2492264A3 (en) | 2003-06-03 | 2012-12-19 | Rib-X Pharmaceuticals, Inc. | Biaryl Heterocyclic Compounds And Methods Of Making And Using The Same |
US8324398B2 (en) | 2003-06-03 | 2012-12-04 | Rib-X Pharmaceuticals, Inc. | Process for the synthesis of biaryl oxazolidinones |
EP1660465B1 (en) * | 2003-07-29 | 2014-12-17 | Melinta Therapeutics, Inc. | Process for the synthesis of biaryl oxazolidinones |
ES2536001T3 (es) * | 2003-07-29 | 2015-05-19 | Melinta Therapeutics, Inc. | Procedimiento para la síntesis de biariloxazolidinonas |
EP1713785A1 (en) | 2003-12-17 | 2006-10-25 | Rib-X Pharmaceuticals, Inc. | Halogenated biaryl heterocyclic compounds and methods of making and using the same |
KR100854211B1 (ko) | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
EP1723159B1 (en) | 2004-02-27 | 2019-06-12 | Melinta Therapeutics, Inc. | Macrocyclic compounds and methods of making and using the same |
JP2008500319A (ja) * | 2004-05-25 | 2008-01-10 | アストラゼネカ アクチボラグ | 細菌感染症の治療のためのmao阻害剤としての3−(4−(2−ジヒドロイソオキサゾール−3−イルピリジン−5−イル)フェニル−5−トリアゾール−1−イルメチルオキサゾリジン−2−オン誘導体 |
US20080064689A1 (en) * | 2004-05-25 | 2008-03-13 | Astrazeneca Ab | 3-[4-(6-Pyridin-3-Yl)-3-Phenyl] -5-(1H-1,2,3-Triazol-1-Ylmethyl)-1,3-Oxazolidin-2-Ones as Antibacterial Agents |
GB0411596D0 (en) * | 2004-05-25 | 2004-06-30 | Astrazeneca Ab | Chemical process |
DOP2005000123A (es) | 2004-07-02 | 2011-07-15 | Merck Sharp & Dohme | Inhibidores de cetp |
US20100286211A1 (en) * | 2004-10-08 | 2010-11-11 | Biswajit Das | Oxazolidinone derivatives as antimicrobials |
EP1874782A1 (en) | 2005-04-15 | 2008-01-09 | Ranbaxy Laboratories Limited | Oxazolidinone derivatives as antimicrobials |
WO2006133397A2 (en) | 2005-06-08 | 2006-12-14 | Rib-X Pharmaceuticals, Inc. | Process for the synthesis of triazoles |
JP2009506066A (ja) | 2005-08-24 | 2009-02-12 | リブ−エックス ファーマシューティカルズ,インコーポレイテッド | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
JP2009506063A (ja) | 2005-08-24 | 2009-02-12 | リブ−エックス ファーマシューティカルズ,インコーポレイテッド | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
CN106220621B (zh) * | 2008-10-10 | 2019-06-11 | 默沙东公司 | 制备噁唑烷酮类的方法及含有噁唑烷酮类的组合物 |
NZ594408A (en) | 2009-02-03 | 2014-03-28 | Trius Therapeutics | Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate |
US8580767B2 (en) | 2009-05-28 | 2013-11-12 | Trius Therapeutics, Inc. | Oxazolidinone containing dimer compounds, compositions and methods to make and use |
KR101561964B1 (ko) | 2013-11-15 | 2015-10-20 | 한국과학기술연구원 | 옥사졸리디논 화합물 및 이를 포함하는 c형 간염 예방 또는 치료용 약학 조성물 |
CN114874131A (zh) * | 2015-02-27 | 2022-08-09 | 海洋规划生物工厂株式会社 | Kakeromycin及其衍生物的制造方法 |
CN106083994B (zh) * | 2016-04-18 | 2019-12-06 | 南京曼杰生物科技有限公司 | 取代的噁唑烷酮水溶性衍生物及其应用 |
US20170333305A1 (en) * | 2016-05-23 | 2017-11-23 | Microban Products Company | Topical skin product having retention property |
WO2019118311A1 (en) | 2017-12-13 | 2019-06-20 | Merck Sharp & Dohme Corp. | Pharmaceutical compositions of tedizolid phosphate |
CN113149924B (zh) * | 2021-03-29 | 2023-11-03 | 苏州大学 | 一种异噁唑啉的简单制备方法 |
CN113831517A (zh) * | 2021-09-09 | 2021-12-24 | 万凯新材料股份有限公司 | 抗菌及抗紫外聚酯的制备方法 |
Family Cites Families (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5043443A (en) * | 1988-07-29 | 1991-08-27 | Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives |
US4948801A (en) | 1988-07-29 | 1990-08-14 | E. I. Du Pont De Nemours And Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
SK283420B6 (sk) * | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
GB9521508D0 (en) | 1995-10-20 | 1995-12-20 | Zeneca Ltd | Chemical compounds |
GB9601666D0 (en) | 1996-01-27 | 1996-03-27 | Zeneca Ltd | Chemical compounds |
GB9702213D0 (en) | 1996-02-24 | 1997-03-26 | Zeneca Ltd | Chemical compounds |
GB9604301D0 (en) | 1996-02-29 | 1996-05-01 | Zeneca Ltd | Chemical compounds |
GB9609919D0 (en) | 1996-05-11 | 1996-07-17 | Zeneca Ltd | Chemical compounds |
GB9614238D0 (en) | 1996-07-06 | 1996-09-04 | Zeneca Ltd | Chemical compounds |
GB9614236D0 (en) | 1996-07-06 | 1996-09-04 | Zeneca Ltd | Chemical compounds |
GB9717807D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
GB9717804D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
EP1007525A1 (en) | 1997-08-29 | 2000-06-14 | Zeneca Limited | Aminometyl oxooxazolidinyl benzene derivatives |
GB9725244D0 (en) | 1997-11-29 | 1998-01-28 | Zeneca Ltd | Chemical compounds |
WO1999033839A1 (en) | 1997-12-26 | 1999-07-08 | Cheil Jedang Corporation | Cephem derivatives and a method for producing the compounds and an antibacterial composition containing the compounds |
GB9812019D0 (en) | 1998-06-05 | 1998-07-29 | Zeneca Ltd | Chemical compounds |
CN1311787A (zh) | 1998-06-05 | 2001-09-05 | 阿斯特拉曾尼卡有限公司 | 噁唑烷酮衍生物、其制备方法以及含有它们的药物组合物 |
AU4543899A (en) | 1998-06-08 | 1999-12-30 | Advanced Medicine, Inc. | Multibinding inhibitors of microsomal triglyceride transferase protein |
GB9821938D0 (en) | 1998-10-09 | 1998-12-02 | Zeneca Ltd | Chemical compounds |
GB9928499D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical processes and intermediates |
GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
BR0111280A (pt) | 2000-06-05 | 2003-06-10 | Dong A Pharm Co Ltd | Novos derivados de oxazolidinona e um processo para a preparação dos mesmos |
DE10034624A1 (de) | 2000-07-17 | 2002-01-31 | Bayer Ag | Aryl-substituierte Thienyl-1,3-oxazolidin-2-one als Cytokin-Inhibitoren |
DE10034625A1 (de) | 2000-07-17 | 2002-01-31 | Bayer Ag | Heterocyclisch substituierte Thienyl-Phenyl-Oxazolidinone |
US20020115669A1 (en) * | 2000-08-31 | 2002-08-22 | Wiedeman Paul E. | Oxazolidinone chemotherapeutic agents |
YU52403A (sh) | 2000-12-26 | 2006-03-03 | Dr.Reddy's Research Foundation | Heterociklična jedinjenja koja imaju antibakterijsko dejstvo, postupak za njihovo dobijanje i farmaceutske smeše koje ih sadrže |
DE60212959T2 (de) | 2001-04-07 | 2007-02-15 | Astrazeneca Ab | Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika |
GB0108794D0 (en) | 2001-04-07 | 2001-05-30 | Astrazeneca Ab | Chemical compound |
GB0108793D0 (en) | 2001-04-07 | 2001-05-30 | Astrazeneca Ab | Chemical compounds |
GB0108764D0 (en) | 2001-04-07 | 2001-05-30 | Astrazeneca Ab | Chemical compounds |
GB0113298D0 (en) | 2001-06-01 | 2001-07-25 | Astrazeneca Ab | Purification process and intermediates |
GB0113299D0 (en) | 2001-06-01 | 2001-07-25 | Astrazeneca Ab | Chemical process & intermediates |
GB0113297D0 (en) | 2001-06-01 | 2001-07-25 | Astrazeneca Ab | Chemical Process |
GB0113300D0 (en) | 2001-06-01 | 2001-07-25 | Astrazeneca Ab | Purification process |
EP1451164A2 (en) | 2001-07-12 | 2004-09-01 | PHARMACIA & UPJOHN COMPANY | Amide derivatives having improved solubility |
GB0118407D0 (en) | 2001-07-27 | 2001-09-19 | Cipla Ltd | Oxazolidinone derivatives as antibacterial agents |
WO2003031443A1 (en) | 2001-10-04 | 2003-04-17 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety |
WO2003031441A1 (en) | 2001-10-04 | 2003-04-17 | Morphochen Aktiengesellschaft Für Kombinatorische Chemie | Multiple action compounds |
JP2005519870A (ja) | 2001-10-25 | 2005-07-07 | アストラゼネカ アクチボラグ | 抗菌活性をもつアリール置換オキサゾリジノン類 |
EP1443930A1 (en) | 2001-10-25 | 2004-08-11 | AstraZeneca AB | Isoxazoline derivatives useful as antimicrobials |
IL163688A0 (en) | 2002-02-28 | 2005-12-18 | Astrazeneca Ab | 3-Cyclyl-5-(nitrogen-containing 5-membered ring)methyl-oxazolidinone derivatives and theiruse as antibacterial agents |
CA2477379A1 (en) | 2002-02-28 | 2003-09-04 | Astrazeneca Ab | Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them |
JP2003335762A (ja) | 2002-05-20 | 2003-11-28 | Meiji Seika Kaisha Ltd | 新規ビフェニル誘導体 |
US7091196B2 (en) | 2002-09-26 | 2006-08-15 | Rib-X Pharmaceuticals, Inc. | Bifunctional heterocyclic compounds and methods of making and using same |
US20060116400A1 (en) * | 2002-11-28 | 2006-06-01 | Astrazeneca Ab | Oxazolidinone and/or isoxazoline derivatives as antibacterial agents |
-
2002
- 2002-09-09 PT PT02765019T patent/PT1427711E/pt unknown
- 2002-09-09 ES ES02765019T patent/ES2244802T3/es not_active Expired - Lifetime
- 2002-09-09 CA CA002459766A patent/CA2459766A1/en not_active Abandoned
- 2002-09-09 CN CNA028223276A patent/CN1639136A/zh active Pending
- 2002-09-09 SI SI200230188T patent/SI1427711T1/sl unknown
- 2002-09-09 KR KR10-2004-7003558A patent/KR20040044886A/ko not_active Application Discontinuation
- 2002-09-09 MX MXPA04002303A patent/MXPA04002303A/es active IP Right Grant
- 2002-09-09 DE DE60205030T patent/DE60205030T2/de not_active Expired - Fee Related
- 2002-09-09 AU AU2002329393A patent/AU2002329393B2/en not_active Ceased
- 2002-09-09 DK DK02765019T patent/DK1427711T3/da active
- 2002-09-09 IL IL16073902A patent/IL160739A0/xx unknown
- 2002-09-09 PL PL02369183A patent/PL369183A1/xx not_active Application Discontinuation
- 2002-09-09 NZ NZ531621A patent/NZ531621A/en unknown
- 2002-09-09 JP JP2003526899A patent/JP2005507386A/ja active Pending
- 2002-09-09 US US10/489,266 patent/US7396847B2/en not_active Expired - Fee Related
- 2002-09-09 EP EP02765019A patent/EP1427711B1/en not_active Expired - Lifetime
- 2002-09-09 RU RU2004111285/04A patent/RU2004111285A/ru not_active Application Discontinuation
- 2002-09-09 HU HU0401005A patent/HUP0401005A3/hu unknown
- 2002-09-09 BR BR0212458-0A patent/BR0212458A/pt not_active IP Right Cessation
- 2002-09-09 WO PCT/GB2002/004120 patent/WO2003022824A1/en active IP Right Grant
- 2002-09-09 AT AT02765019T patent/ATE299502T1/de not_active IP Right Cessation
- 2002-09-11 AR ARP020103440A patent/AR036778A1/es unknown
-
2004
- 2004-03-09 CO CO04021466A patent/CO5560609A2/es not_active Application Discontinuation
- 2004-03-10 IS IS7175A patent/IS7175A/is unknown
- 2004-04-05 NO NO20041428A patent/NO327010B1/no not_active IP Right Cessation
- 2004-10-29 HK HK04108506A patent/HK1065789A1/xx not_active IP Right Cessation
-
2008
- 2008-05-28 US US12/128,135 patent/US20100137243A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
RU2004111285A (ru) | 2005-10-10 |
DK1427711T3 (da) | 2005-10-17 |
EP1427711B1 (en) | 2005-07-13 |
CO5560609A2 (es) | 2005-09-30 |
NZ531621A (en) | 2005-06-24 |
CA2459766A1 (en) | 2003-03-20 |
US20100137243A1 (en) | 2010-06-03 |
IS7175A (is) | 2004-03-10 |
DE60205030T2 (de) | 2006-04-20 |
MXPA04002303A (es) | 2004-06-29 |
PT1427711E (pt) | 2005-11-30 |
PL369183A1 (en) | 2005-04-18 |
CN1639136A (zh) | 2005-07-13 |
HUP0401005A3 (en) | 2007-11-28 |
US7396847B2 (en) | 2008-07-08 |
HUP0401005A2 (hu) | 2004-08-30 |
HK1065789A1 (en) | 2005-03-04 |
NO20041428L (no) | 2004-06-08 |
KR20040044886A (ko) | 2004-05-31 |
ATE299502T1 (de) | 2005-07-15 |
EP1427711A1 (en) | 2004-06-16 |
AR036778A1 (es) | 2004-10-06 |
ES2244802T3 (es) | 2005-12-16 |
BR0212458A (pt) | 2004-10-19 |
DE60205030D1 (de) | 2005-08-18 |
SI1427711T1 (sl) | 2005-12-31 |
WO2003022824A1 (en) | 2003-03-20 |
NO327010B1 (no) | 2009-04-06 |
JP2005507386A (ja) | 2005-03-17 |
AU2002329393B2 (en) | 2008-06-12 |
US20050107435A1 (en) | 2005-05-19 |
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