DE60205030D1 - Oxazolidinon- und/oder isoxazolinderivate als antibakterielle mittel - Google Patents

Oxazolidinon- und/oder isoxazolinderivate als antibakterielle mittel

Info

Publication number
DE60205030D1
DE60205030D1 DE60205030T DE60205030T DE60205030D1 DE 60205030 D1 DE60205030 D1 DE 60205030D1 DE 60205030 T DE60205030 T DE 60205030T DE 60205030 T DE60205030 T DE 60205030T DE 60205030 D1 DE60205030 D1 DE 60205030D1
Authority
DE
Germany
Prior art keywords
oxazolidinone
antibacterial agents
isoxazoline derivatives
isoxazoline
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60205030T
Other languages
English (en)
Other versions
DE60205030T2 (de
Inventor
Barry Gravestock
James Hales
Lingard Swain
Irene Hauck
Dennett Mills
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0121942A external-priority patent/GB0121942D0/en
Priority claimed from GB0215420A external-priority patent/GB0215420D0/en
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of DE60205030D1 publication Critical patent/DE60205030D1/de
Application granted granted Critical
Publication of DE60205030T2 publication Critical patent/DE60205030T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE60205030T 2001-09-11 2002-09-09 Oxazolidinon- und/oder isoxazolinderivate als antibakterielle mittel Expired - Fee Related DE60205030T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0121942 2001-09-11
GB0121942A GB0121942D0 (en) 2001-09-11 2001-09-11 Chemical compounds
GB0215420 2002-07-04
GB0215420A GB0215420D0 (en) 2002-07-04 2002-07-04 Chemical compounds
PCT/GB2002/004120 WO2003022824A1 (en) 2001-09-11 2002-09-09 Oxazolidinone and/or isoxazoline as antibacterial agents

Publications (2)

Publication Number Publication Date
DE60205030D1 true DE60205030D1 (de) 2005-08-18
DE60205030T2 DE60205030T2 (de) 2006-04-20

Family

ID=26246531

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60205030T Expired - Fee Related DE60205030T2 (de) 2001-09-11 2002-09-09 Oxazolidinon- und/oder isoxazolinderivate als antibakterielle mittel

Country Status (26)

Country Link
US (2) US7396847B2 (de)
EP (1) EP1427711B1 (de)
JP (1) JP2005507386A (de)
KR (1) KR20040044886A (de)
CN (1) CN1639136A (de)
AR (1) AR036778A1 (de)
AT (1) ATE299502T1 (de)
AU (1) AU2002329393B2 (de)
BR (1) BR0212458A (de)
CA (1) CA2459766A1 (de)
CO (1) CO5560609A2 (de)
DE (1) DE60205030T2 (de)
DK (1) DK1427711T3 (de)
ES (1) ES2244802T3 (de)
HK (1) HK1065789A1 (de)
HU (1) HUP0401005A3 (de)
IL (1) IL160739A0 (de)
IS (1) IS7175A (de)
MX (1) MXPA04002303A (de)
NO (1) NO327010B1 (de)
NZ (1) NZ531621A (de)
PL (1) PL369183A1 (de)
PT (1) PT1427711E (de)
RU (1) RU2004111285A (de)
SI (1) SI1427711T1 (de)
WO (1) WO2003022824A1 (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6667299B1 (en) * 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
US7022705B2 (en) 2001-10-25 2006-04-04 Astrazeneca Ab Isoxazoline derivatives useful as antimicrobials
NZ535591A (en) 2002-02-28 2006-07-28 Astrazeneca Ab Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them
BR0308056A (pt) * 2002-02-28 2004-12-07 Astrazeneca Ab Composto, pró-droga, método para a produção de um efeito antibacteriano em um animal de sangue quente, uso de um composto, composição farmacêutica, e, processo para a preparação de um composto
MXPA04010099A (es) * 2002-04-25 2004-12-13 Basf Ag Isoxazolinas sustituidas por 3 - heteroarilo.
TW200420573A (en) * 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
AU2003302404B2 (en) * 2002-11-28 2008-06-19 Astrazeneca Ab Oxazolidinone and / or isoxazoline derivatives as antibacterial agents
GB0227701D0 (en) * 2002-11-28 2003-01-08 Astrazeneca Ab Chemical compounds
CA2507628A1 (en) * 2002-11-28 2004-06-10 Astrazeneca Ab Oxazolidinones as antibacterial agents
GB0229522D0 (en) * 2002-12-19 2003-01-22 Astrazeneca Ab Chemical compounds
GB0229521D0 (en) * 2002-12-19 2003-01-22 Astrazeneca Ab Chemical compounds
GB0229526D0 (en) * 2002-12-19 2003-01-22 Astrazeneca Ab Chemical compounds
GB0304723D0 (en) * 2003-03-01 2003-04-02 Astrazeneca Ab Chemical compounds
TW200500360A (en) 2003-03-01 2005-01-01 Astrazeneca Ab Hydroxymethyl compounds
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
WO2005012271A2 (en) * 2003-07-29 2005-02-10 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
PT1656370E (pt) 2003-06-03 2012-11-29 Rib X Pharmaceuticals Inc Compostos biaril-heterocíclicos e métodos de os produzir e de os utilizar
ES2536001T3 (es) * 2003-07-29 2015-05-19 Melinta Therapeutics, Inc. Procedimiento para la síntesis de biariloxazolidinonas
TW200526649A (en) 2003-12-17 2005-08-16 Rib X Pharmaceuticals Inc Halogenated biaryl heterocyclic compounds and methods of making and using the same
KR100854211B1 (ko) * 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
US8202843B2 (en) 2004-02-27 2012-06-19 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
GB0411596D0 (en) * 2004-05-25 2004-06-30 Astrazeneca Ab Chemical process
US20080064689A1 (en) * 2004-05-25 2008-03-13 Astrazeneca Ab 3-[4-(6-Pyridin-3-Yl)-3-Phenyl] -5-(1H-1,2,3-Triazol-1-Ylmethyl)-1,3-Oxazolidin-2-Ones as Antibacterial Agents
CA2567457A1 (en) * 2004-05-25 2005-12-08 Astrazeneca Ab 3- (4- (2-dihydroisoxazol-3-ylpyridin-5-yl) phenyl) -5-triazol-1-ylmethyloxazolidin-2-one derivaives as mao inhibitors for the treatment of bacterial infections
DOP2005000123A (es) 2004-07-02 2011-07-15 Merck Sharp & Dohme Inhibidores de cetp
EP1799677A1 (de) * 2004-10-08 2007-06-27 Ranbaxy Laboratories Limited Oxazolidinon-derivate mit antimikrobieller funktion
US7592335B2 (en) 2005-04-15 2009-09-22 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
ATE496914T1 (de) 2005-06-08 2011-02-15 Rib X Pharmaceuticals Inc Verfahren zur synthese von triazolen
DK1934238T3 (en) 2005-08-24 2017-09-18 Melinta Therapeutics Inc TRIAZOL COMPOUNDS AND METHODS FOR THE PREPARATION AND USE OF THESE
US8470985B2 (en) 2005-08-24 2013-06-25 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
WO2010042887A2 (en) 2008-10-10 2010-04-15 Trius Therapeutics Methods for preparing oxazolidinones and compositions containing them
AU2010210627B2 (en) 2009-02-03 2016-03-03 Merck Sharp & Dohme Llc Crystalline form of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate
US8580767B2 (en) 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use
KR101561964B1 (ko) 2013-11-15 2015-10-20 한국과학기술연구원 옥사졸리디논 화합물 및 이를 포함하는 c형 간염 예방 또는 치료용 약학 조성물
WO2016136963A1 (ja) * 2015-02-27 2016-09-01 彰彦 石川 カケロマイシンおよびその誘導体の製造方法
CN106083994B (zh) * 2016-04-18 2019-12-06 南京曼杰生物科技有限公司 取代的噁唑烷酮水溶性衍生物及其应用
US20170333305A1 (en) * 2016-05-23 2017-11-23 Microban Products Company Topical skin product having retention property
US11452719B2 (en) 2017-12-13 2022-09-27 Merck Sharp & Dohme Llc Pharmaceutical compositions of tedizolid phosphate
CN113149924B (zh) * 2021-03-29 2023-11-03 苏州大学 一种异噁唑啉的简单制备方法
CN113831517A (zh) * 2021-09-09 2021-12-24 万凯新材料股份有限公司 抗菌及抗紫外聚酯的制备方法

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4948801A (en) 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US5043443A (en) * 1988-07-29 1991-08-27 Du Pont Merck Pharmaceutical Company Aminomethyloxooxazolidinyl arylbenzene derivatives
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
GB9521508D0 (en) 1995-10-20 1995-12-20 Zeneca Ltd Chemical compounds
GB9601666D0 (en) 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9604301D0 (en) 1996-02-29 1996-05-01 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
GB9614236D0 (en) 1996-07-06 1996-09-04 Zeneca Ltd Chemical compounds
GB9614238D0 (en) 1996-07-06 1996-09-04 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
JP2001514259A (ja) 1997-08-29 2001-09-11 ゼネカ・リミテッド アミノメチルオキソオキサゾリジニルベンゼン誘導体
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
WO1999033839A1 (en) 1997-12-26 1999-07-08 Cheil Jedang Corporation Cephem derivatives and a method for producing the compounds and an antibacterial composition containing the compounds
GB9812019D0 (en) 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds
TR200003595T2 (tr) 1998-06-05 2001-07-23 Astrazeneca Ab Kimyasal bileşikler
CA2319495A1 (en) 1998-06-08 1999-12-16 Advanced Medicine, Inc. Multibinding inhibitors of microsomal triglyceride transferase protein
GB9821938D0 (en) 1998-10-09 1998-12-02 Zeneca Ltd Chemical compounds
GB9928499D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical processes and intermediates
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
EP1289984A4 (de) 2000-06-05 2004-11-24 Dong A Pharm Co Ltd Neue oxazolidinderivate und ein verfahren zu ihrer herstellung
DE10034625A1 (de) 2000-07-17 2002-01-31 Bayer Ag Heterocyclisch substituierte Thienyl-Phenyl-Oxazolidinone
DE10034624A1 (de) 2000-07-17 2002-01-31 Bayer Ag Aryl-substituierte Thienyl-1,3-oxazolidin-2-one als Cytokin-Inhibitoren
US20020115669A1 (en) * 2000-08-31 2002-08-22 Wiedeman Paul E. Oxazolidinone chemotherapeutic agents
YU52403A (sh) 2000-12-26 2006-03-03 Dr.Reddy's Research Foundation Heterociklična jedinjenja koja imaju antibakterijsko dejstvo, postupak za njihovo dobijanje i farmaceutske smeše koje ih sadrže
GB0108794D0 (en) 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compound
ES2268011T3 (es) 2001-04-07 2007-03-16 Astrazeneca Ab Oxazolidinonas que contienen un grupo sulfonimida como antibioticos.
GB0108793D0 (en) 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
GB0108764D0 (en) 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
GB0113299D0 (en) 2001-06-01 2001-07-25 Astrazeneca Ab Chemical process & intermediates
GB0113297D0 (en) 2001-06-01 2001-07-25 Astrazeneca Ab Chemical Process
GB0113298D0 (en) 2001-06-01 2001-07-25 Astrazeneca Ab Purification process and intermediates
GB0113300D0 (en) 2001-06-01 2001-07-25 Astrazeneca Ab Purification process
US7049443B2 (en) 2001-07-12 2006-05-23 Pharmacia & Upjohn Company Amide-containing compound having improved solubility and method of improving the solubility of an amide-containing compound
GB0118407D0 (en) 2001-07-27 2001-09-19 Cipla Ltd Oxazolidinone derivatives as antibacterial agents
WO2003031443A1 (de) 2001-10-04 2003-04-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Dual action antibiotics
WO2003031441A1 (en) 2001-10-04 2003-04-17 Morphochen Aktiengesellschaft Für Kombinatorische Chemie Multiple action compounds
US20050043374A1 (en) 2001-10-25 2005-02-24 Gravestock Michael Barry Aryl substituted oxazolidinones with antibacterial activity
US7022705B2 (en) 2001-10-25 2006-04-04 Astrazeneca Ab Isoxazoline derivatives useful as antimicrobials
NZ535591A (en) 2002-02-28 2006-07-28 Astrazeneca Ab Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them
BR0308056A (pt) 2002-02-28 2004-12-07 Astrazeneca Ab Composto, pró-droga, método para a produção de um efeito antibacteriano em um animal de sangue quente, uso de um composto, composição farmacêutica, e, processo para a preparação de um composto
JP2003335762A (ja) 2002-05-20 2003-11-28 Meiji Seika Kaisha Ltd 新規ビフェニル誘導体
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
AU2003302404B2 (en) * 2002-11-28 2008-06-19 Astrazeneca Ab Oxazolidinone and / or isoxazoline derivatives as antibacterial agents

Also Published As

Publication number Publication date
WO2003022824A1 (en) 2003-03-20
ES2244802T3 (es) 2005-12-16
PL369183A1 (en) 2005-04-18
IL160739A0 (en) 2004-08-31
HK1065789A1 (en) 2005-03-04
AU2002329393B2 (en) 2008-06-12
EP1427711B1 (de) 2005-07-13
US7396847B2 (en) 2008-07-08
SI1427711T1 (sl) 2005-12-31
CN1639136A (zh) 2005-07-13
NO327010B1 (no) 2009-04-06
NZ531621A (en) 2005-06-24
BR0212458A (pt) 2004-10-19
KR20040044886A (ko) 2004-05-31
US20050107435A1 (en) 2005-05-19
CO5560609A2 (es) 2005-09-30
US20100137243A1 (en) 2010-06-03
JP2005507386A (ja) 2005-03-17
EP1427711A1 (de) 2004-06-16
HUP0401005A3 (en) 2007-11-28
ATE299502T1 (de) 2005-07-15
NO20041428L (no) 2004-06-08
RU2004111285A (ru) 2005-10-10
DK1427711T3 (da) 2005-10-17
IS7175A (is) 2004-03-10
DE60205030T2 (de) 2006-04-20
CA2459766A1 (en) 2003-03-20
HUP0401005A2 (hu) 2004-08-30
MXPA04002303A (es) 2004-06-29
AR036778A1 (es) 2004-10-06
PT1427711E (pt) 2005-11-30

Similar Documents

Publication Publication Date Title
ATE299502T1 (de) Oxazolidinon- und/oder isoxazolinderivate als antibakterielle mittel
IL168747A0 (en) Oxazolidinone and/or isoxazoline derivatives as antibacterial agents
ATE398110T1 (de) 3-aminochinazolin-2,4-dione als antibakterielle mittel
DE60214413D1 (de) Thiophen- und thiazolsulfonamide als antineoplastische mittel
DE602004012891D1 (de) Pyrido- und pyrimidopyrimidinderivate als anti-proliferative mittel
ATE457641T1 (de) Synergistische herbizide mittel
DE60026540D1 (de) Mutilin-derivate und ihre anwendung als antibakterielle mittel
FR14C0066I2 (fr) 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles
DE60142180D1 (de) Lichtstabilisierte antimikrobielle mittel
DE60238194D1 (de) Isoxazolinderivate und herbizide
DE60317711D1 (de) Kationische porphyrin-derivate als antibakterielle mittel
GB0303836D0 (en) Oxazolidinones and their use as antibacterial agents
BR0205514B1 (pt) processos de tratamento de cabelo
DE60304188D1 (de) Ä1,4ÜDIAZOCINOÄ7,8,1-hiÜINDOLDERIVATE ALS ANTIPSYCHOTISCHE MITTEL UND MITTEL GEGEN OBESITÄT
DE50115239D1 (de) Herbizide Mittel
EE200400004A (et) Oksasolidinoonide derivaadid kui antibakteriaalsed ained
ATE437860T1 (de) 2-hydroxy-mutilin-carbamat derivate und ihre anwendung als antibakterielle mittel
ATE246189T1 (de) Bizyklische oxazolidinone als antibakterielle mittel
AU2003292422A1 (en) Oxazolidinone derivatives and their use as antibacterial agents
ATE326452T1 (de) Piperidinyloxy- und pyrrolidinyloxyphenyloxazolidinone als antibakterielle mittel
DE60223576D1 (de) Hautbehandlungszusammensetzung
FR2813777B1 (fr) Gant reversible jetable
ATE337322T1 (de) Isoxazolin-derivate als antidepressiva
DE60207318D1 (de) Festes kosmetisches Mittel
DE60230470D1 (de) Festes kosmetisches Mittel

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee