IL159014A0 - Use of il-18 inhibitors for treating or preventing cns injuries - Google Patents
Use of il-18 inhibitors for treating or preventing cns injuriesInfo
- Publication number
- IL159014A0 IL159014A0 IL15901402A IL15901402A IL159014A0 IL 159014 A0 IL159014 A0 IL 159014A0 IL 15901402 A IL15901402 A IL 15901402A IL 15901402 A IL15901402 A IL 15901402A IL 159014 A0 IL159014 A0 IL 159014A0
- Authority
- IL
- Israel
- Prior art keywords
- inhibitors
- treating
- cns injuries
- preventing cns
- preventing
- Prior art date
Links
- 230000006378 damage Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01112067 | 2001-05-25 | ||
| PCT/EP2002/005666 WO2002096456A1 (en) | 2001-05-25 | 2002-05-23 | Use of il-18 inhibitors for treating or preventing cns injuries |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL159014A0 true IL159014A0 (en) | 2004-05-12 |
Family
ID=8177454
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15901402A IL159014A0 (en) | 2001-05-25 | 2002-05-23 | Use of il-18 inhibitors for treating or preventing cns injuries |
| IL159014A IL159014A (en) | 2001-05-25 | 2003-11-23 | Use of IL-18 inhibitors for the manufacture of a medicament for the treatment and / or prevention of traumatic brain injury |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL159014A IL159014A (en) | 2001-05-25 | 2003-11-23 | Use of IL-18 inhibitors for the manufacture of a medicament for the treatment and / or prevention of traumatic brain injury |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US7655616B2 (de) |
| EP (1) | EP1390070B1 (de) |
| JP (1) | JP4344142B2 (de) |
| KR (1) | KR20040030625A (de) |
| CN (1) | CN1305529C (de) |
| AU (1) | AU2002314103B2 (de) |
| BG (1) | BG66395B1 (de) |
| BR (1) | BR0210007A (de) |
| CA (1) | CA2445664C (de) |
| CY (1) | CY1119190T1 (de) |
| CZ (1) | CZ307321B6 (de) |
| DK (1) | DK1390070T3 (de) |
| EA (1) | EA006744B1 (de) |
| EE (1) | EE05263B1 (de) |
| ES (1) | ES2617084T3 (de) |
| HR (1) | HRP20030842B1 (de) |
| HU (1) | HU230294B1 (de) |
| IL (2) | IL159014A0 (de) |
| LT (1) | LT1390070T (de) |
| ME (1) | ME00550B (de) |
| MX (1) | MXPA03010743A (de) |
| NO (1) | NO331882B1 (de) |
| PL (1) | PL216228B1 (de) |
| PT (1) | PT1390070T (de) |
| RS (1) | RS56006B1 (de) |
| SK (1) | SK288413B6 (de) |
| UA (1) | UA80396C2 (de) |
| WO (1) | WO2002096456A1 (de) |
| ZA (1) | ZA200308172B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5074030B2 (ja) | 2003-05-13 | 2012-11-14 | メルク セローノ ソシエテ アノニム | Ｉｌ−１８結合タンパク質の活性変異体とその医学的応用 |
| AU2005258569B2 (en) * | 2004-06-30 | 2012-05-03 | Atsuo Sekiyama | Indicator agent for noninflammatory stress response and use thereof |
| AU2006254103B2 (en) | 2005-06-03 | 2012-09-06 | Ares Trading S.A. | Production of recombinant IL-18 binding protein |
| SI1888100T1 (sl) * | 2005-06-03 | 2012-01-31 | Merck Serono Sa | Uporaba izooblik il-18pb za zdravljenje in/ali prepreäśevanje nevroloĺ kih vnetnih bolezni |
| ATE529433T1 (de) | 2005-06-10 | 2011-11-15 | Ares Trading Sa | Verfahren zur reinigung eines il-18-bindenden proteins |
| US8685400B2 (en) | 2007-07-30 | 2014-04-01 | University Of Miami | Modulating inflammasome activity and inflammation in the central nervous system |
| PH12016500425B1 (en) * | 2013-09-05 | 2022-07-29 | Ab2 Bio Sa | Il-18 binding protein (il-18bp) in inflammatory diseases |
| JP7274259B2 (ja) * | 2015-03-05 | 2023-05-16 | エイビー２ バイオ ソシエテアノニム | 炎症性疾患におけるｉｌ－１８結合タンパク質（ｉｌ－１８ｂｐ）および抗体 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0873453A (ja) * | 1994-09-02 | 1996-03-19 | Otsuka Pharmaceut Co Ltd | サイトカイン阻害剤 |
| IL121860A0 (en) * | 1997-08-14 | 1998-02-22 | Yeda Res & Dev | Interleukin-18 binding proteins their preparation and use |
| DE69925581T2 (de) * | 1998-03-09 | 2006-04-27 | Vertex Pharmaceuticals Inc., Cambridge | 1,2-diazepanderivate als inhibitoren des interleukin-1beta umwandelnden enzyms |
| CA2276216A1 (en) * | 1998-06-24 | 1999-12-24 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | An artificial peptide capable of neutralizing the biological activity of interleukin-18 |
| KR100798545B1 (ko) * | 2000-05-05 | 2008-01-28 | 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. | 죽상경화증의 치료 또는 예방을 위한 ｉｌ-18 저해물질의용도 |
| AU2001266289A1 (en) * | 2000-06-23 | 2002-01-02 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | 2-arachidonylglycerol (2-ag) - an inhibitor of tumor necrosis factor -alfa and neuroprotector of brain in closed head injury |
| AU2002224417A1 (en) * | 2000-10-18 | 2002-04-29 | Immunex Corporation | Methods for treating il-18 mediated disorders |
| US6671553B1 (en) * | 2001-05-23 | 2003-12-30 | Pacesetter, Inc. | Implantable cardiac lead having terminating connector strain relief and method of manufacture |
-
2002
- 2002-05-23 ME MEP-2008-618A patent/ME00550B/me unknown
- 2002-05-23 CZ CZ2003-3268A patent/CZ307321B6/cs not_active IP Right Cessation
- 2002-05-23 EA EA200301299A patent/EA006744B1/ru not_active IP Right Cessation
- 2002-05-23 DK DK02740641.2T patent/DK1390070T3/en active
- 2002-05-23 RS YU89403A patent/RS56006B1/sr unknown
- 2002-05-23 ES ES02740641.2T patent/ES2617084T3/es not_active Expired - Lifetime
- 2002-05-23 CA CA2445664A patent/CA2445664C/en not_active Expired - Lifetime
- 2002-05-23 MX MXPA03010743A patent/MXPA03010743A/es active IP Right Grant
- 2002-05-23 JP JP2002592965A patent/JP4344142B2/ja not_active Expired - Lifetime
- 2002-05-23 AU AU2002314103A patent/AU2002314103B2/en not_active Expired
- 2002-05-23 HU HU0304067A patent/HU230294B1/hu unknown
- 2002-05-23 WO PCT/EP2002/005666 patent/WO2002096456A1/en not_active Ceased
- 2002-05-23 PT PT2740641T patent/PT1390070T/pt unknown
- 2002-05-23 US US10/478,614 patent/US7655616B2/en not_active Expired - Lifetime
- 2002-05-23 SK SK1603-2003A patent/SK288413B6/sk not_active IP Right Cessation
- 2002-05-23 IL IL15901402A patent/IL159014A0/xx unknown
- 2002-05-23 EP EP02740641.2A patent/EP1390070B1/de not_active Expired - Lifetime
- 2002-05-23 PL PL367545A patent/PL216228B1/pl unknown
- 2002-05-23 EE EEP200300582A patent/EE05263B1/xx unknown
- 2002-05-23 LT LTEP02740641.2T patent/LT1390070T/lt unknown
- 2002-05-23 BR BR0210007-0A patent/BR0210007A/pt not_active Application Discontinuation
- 2002-05-23 HR HRP20030842AA patent/HRP20030842B1/hr not_active IP Right Cessation
- 2002-05-23 KR KR10-2003-7015310A patent/KR20040030625A/ko not_active Ceased
- 2002-05-23 UA UA20031212328A patent/UA80396C2/uk unknown
- 2002-05-23 CN CNB028147510A patent/CN1305529C/zh not_active Expired - Lifetime
-
2003
- 2003-10-21 ZA ZA200308172A patent/ZA200308172B/xx unknown
- 2003-11-20 NO NO20035160A patent/NO331882B1/no not_active IP Right Cessation
- 2003-11-23 IL IL159014A patent/IL159014A/en active IP Right Grant
- 2003-12-15 BG BG108451A patent/BG66395B1/bg unknown
-
2017
- 2017-05-08 CY CY20171100494T patent/CY1119190T1/el unknown
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