IL152804A0 - Methods for refolding proteins containing free cysteine residues - Google Patents
Methods for refolding proteins containing free cysteine residuesInfo
- Publication number
- IL152804A0 IL152804A0 IL15280401A IL15280401A IL152804A0 IL 152804 A0 IL152804 A0 IL 152804A0 IL 15280401 A IL15280401 A IL 15280401A IL 15280401 A IL15280401 A IL 15280401A IL 152804 A0 IL152804 A0 IL 152804A0
- Authority
- IL
- Israel
- Prior art keywords
- methods
- cysteine residues
- proteins containing
- containing free
- free cysteine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/515—Angiogenesic factors; Angiogenin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormones [GH] (Somatotropin)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20461700P | 2000-05-16 | 2000-05-16 | |
PCT/US2001/016088 WO2001087925A2 (en) | 2000-05-16 | 2001-05-16 | Methods for refolding proteins containing free cysteine residues |
Publications (1)
Publication Number | Publication Date |
---|---|
IL152804A0 true IL152804A0 (en) | 2003-06-24 |
Family
ID=22758675
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15280401A IL152804A0 (en) | 2000-05-16 | 2001-05-16 | Methods for refolding proteins containing free cysteine residues |
IL152804A IL152804A (en) | 2000-05-16 | 2002-11-12 | Methods for refolding proteins containing free cysteine residues |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL152804A IL152804A (en) | 2000-05-16 | 2002-11-12 | Methods for refolding proteins containing free cysteine residues |
Country Status (13)
Country | Link |
---|---|
US (3) | US7306931B2 (xx) |
EP (1) | EP1284987B1 (xx) |
JP (2) | JP4873818B2 (xx) |
CN (1) | CN1318443C (xx) |
AT (1) | ATE367398T1 (xx) |
AU (2) | AU2001274853B2 (xx) |
CA (1) | CA2408851C (xx) |
DE (1) | DE60129432T2 (xx) |
ES (1) | ES2290142T3 (xx) |
HK (1) | HK1050014A1 (xx) |
IL (2) | IL152804A0 (xx) |
NZ (1) | NZ522847A (xx) |
WO (1) | WO2001087925A2 (xx) |
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2001
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- 2001-05-16 JP JP2001585144A patent/JP4873818B2/ja not_active Expired - Fee Related
- 2001-05-16 WO PCT/US2001/016088 patent/WO2001087925A2/en active IP Right Grant
- 2001-05-16 IL IL15280401A patent/IL152804A0/xx unknown
- 2001-05-16 US US10/276,358 patent/US7306931B2/en not_active Expired - Lifetime
- 2001-05-16 DE DE60129432T patent/DE60129432T2/de not_active Expired - Lifetime
- 2001-05-16 AU AU2001274853A patent/AU2001274853B2/en not_active Ceased
- 2001-05-16 ES ES01941504T patent/ES2290142T3/es not_active Expired - Lifetime
- 2001-05-16 AT AT01941504T patent/ATE367398T1/de not_active IP Right Cessation
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- 2001-05-16 CN CNB018128556A patent/CN1318443C/zh not_active Expired - Fee Related
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ES2290142T3 (es) | 2008-02-16 |
JP5517991B2 (ja) | 2014-06-11 |
CN1318443C (zh) | 2007-05-30 |
CN1443194A (zh) | 2003-09-17 |
US8932828B2 (en) | 2015-01-13 |
JP4873818B2 (ja) | 2012-02-08 |
NZ522847A (en) | 2004-11-26 |
US20110189124A1 (en) | 2011-08-04 |
CA2408851C (en) | 2011-07-12 |
AU7485301A (en) | 2001-11-26 |
WO2001087925A3 (en) | 2002-08-01 |
US20090269804A1 (en) | 2009-10-29 |
DE60129432D1 (de) | 2007-08-30 |
US20040018586A1 (en) | 2004-01-29 |
EP1284987B1 (en) | 2007-07-18 |
ATE367398T1 (de) | 2007-08-15 |
US7306931B2 (en) | 2007-12-11 |
IL152804A (en) | 2010-11-30 |
JP2004508014A (ja) | 2004-03-18 |
JP2011173911A (ja) | 2011-09-08 |
EP1284987A2 (en) | 2003-02-26 |
HK1050014A1 (en) | 2003-06-06 |
AU2001274853B2 (en) | 2007-03-22 |
DE60129432T2 (de) | 2008-04-17 |
AU2001274853C1 (en) | 2001-11-26 |
WO2001087925A2 (en) | 2001-11-22 |
CA2408851A1 (en) | 2001-11-22 |
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