IL143730A0 - Blood pool agents for nuclear magnetic resonance diagnostics - Google Patents

Blood pool agents for nuclear magnetic resonance diagnostics

Info

Publication number
IL143730A0
IL143730A0 IL14373099A IL14373099A IL143730A0 IL 143730 A0 IL143730 A0 IL 143730A0 IL 14373099 A IL14373099 A IL 14373099A IL 14373099 A IL14373099 A IL 14373099A IL 143730 A0 IL143730 A0 IL 143730A0
Authority
IL
Israel
Prior art keywords
magnetic resonance
nuclear magnetic
blood pool
pool agents
resonance diagnostics
Prior art date
Application number
IL14373099A
Other languages
English (en)
Original Assignee
Bracco Imaging Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Imaging Spa filed Critical Bracco Imaging Spa
Publication of IL143730A0 publication Critical patent/IL143730A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/927—Diagnostic contrast agent
    • Y10S977/928—X-ray agent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/927—Diagnostic contrast agent
    • Y10S977/929—Ultrasound contrast agent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/927—Diagnostic contrast agent
    • Y10S977/93—MRI contrast agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL14373099A 1998-12-23 1999-12-16 Blood pool agents for nuclear magnetic resonance diagnostics IL143730A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI002802A IT1304501B1 (it) 1998-12-23 1998-12-23 Uso di derivati di acidi biliari coniugati con complessi metallicicome "blood pool agents" per l'indagine diagnostica tramite risonanza
PCT/EP1999/010002 WO2000038738A1 (en) 1998-12-23 1999-12-16 Blood pool agents for nuclear magnetic resonance diagnostics

Publications (1)

Publication Number Publication Date
IL143730A0 true IL143730A0 (en) 2002-04-21

Family

ID=11381326

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14373099A IL143730A0 (en) 1998-12-23 1999-12-16 Blood pool agents for nuclear magnetic resonance diagnostics
IL143730A IL143730A (en) 1998-12-23 2001-06-13 Blood factors for diagnosis using nuclear magnetic resonance

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL143730A IL143730A (en) 1998-12-23 2001-06-13 Blood factors for diagnosis using nuclear magnetic resonance

Country Status (20)

Country Link
US (1) US6461588B1 (https=)
EP (2) EP1935435B1 (https=)
JP (1) JP4733271B2 (https=)
KR (1) KR100736298B1 (https=)
CN (2) CN100450996C (https=)
AT (1) ATE405296T1 (https=)
AU (1) AU773876B2 (https=)
CA (1) CA2355888C (https=)
CZ (1) CZ302195B6 (https=)
DE (1) DE69939398D1 (https=)
HK (1) HK1042432B (https=)
HU (1) HU228048B1 (https=)
IL (2) IL143730A0 (https=)
IT (1) IT1304501B1 (https=)
MX (1) MXPA01006344A (https=)
NO (1) NO322551B1 (https=)
PL (1) PL196474B1 (https=)
RU (2) RU2395490C2 (https=)
WO (1) WO2000038738A1 (https=)
ZA (1) ZA200104820B (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW319763B (https=) * 1995-02-01 1997-11-11 Epix Medical Inc
KR20010030854A (ko) 1997-10-02 2001-04-16 로퍼, 랜달 비. 인터벤셔날 요법을 모니터하기 위한 콘트라스트 강화된진단 영상화 방법
IT1317862B1 (it) * 2000-02-29 2003-07-15 Bracco Spa Coniugati di acidi biliari con chelati complessi di ioni metallici eloro uso.
IT1318485B1 (it) * 2000-04-21 2003-08-25 Bracco Spa Uso di derivati di acidi biliari coniugati con complessi di ionimetallici nella visualizzazione diagnostica di sistemi microvascolari
EP1361847A2 (en) * 2000-10-06 2003-11-19 Xenoport, Inc. Bile-acid conjugates for providing sustained systemic concentrations of drugs
EP1229041A1 (en) * 2001-02-05 2002-08-07 Bracco Imaging S.p.A. A process for the preparation of 3-Glutamido bile ester derivatives using N-tBoc methyl pyroglutamate
US7053076B2 (en) 2001-08-29 2006-05-30 Xenoport, Inc. Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs
EP1302465A1 (en) 2001-10-11 2003-04-16 BRACCO IMAGING S.p.A. Enhanced substrate imaging by reversible binding to a paramagnetic complex
US7850947B2 (en) 2003-01-13 2010-12-14 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7226577B2 (en) * 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
US7611692B2 (en) * 2003-01-13 2009-11-03 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
CA2512310C (en) * 2003-01-13 2012-09-25 Bracco Imaging S.P.A. Improved linkers for radiopharmaceutical compounds
US7922998B2 (en) 2003-01-13 2011-04-12 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US8420050B2 (en) * 2003-01-13 2013-04-16 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
CA2549318A1 (en) * 2003-12-24 2005-07-28 Enrico Cappelletti Improved gastrin releasing peptide compounds
RU2425831C2 (ru) * 2005-12-02 2011-08-10 Джи-И Хелткер АС Мультимерные контрастные агенты для магнитного резонанса
WO2009009760A1 (en) 2007-07-11 2009-01-15 Board Of Regents, The University Of Texas System Seeds and markers for use in imaging
CN101845112B (zh) * 2010-06-02 2011-09-14 华东理工大学 一种基于高分子纳米粒子的高灵敏性核磁共振成像造影剂的制备方法
CN103442737B (zh) 2011-01-20 2017-03-29 得克萨斯系统大学董事会 Mri标记、递送和提取系统及其制造方法和用途
AU2013229631B2 (en) 2012-03-05 2017-09-14 Bracco Imaging Spa Dynamic Contrast Enhanced MRI method and agents for the assessment of the macromolecular transport within pathologic tissues
CN102766188B (zh) * 2012-07-24 2016-01-13 上海交通大学 胆固醇衍生物、螯合物、重组高密度脂蛋白及其用途
GB201421163D0 (en) * 2014-11-28 2015-01-14 Ge Healthcare As Formulations of metal complexes
US10093741B1 (en) 2017-05-05 2018-10-09 Fusion Pharmaceuticals Inc. IGF-1R monoclonal antibodies and uses thereof
KR102612882B1 (ko) 2017-05-05 2023-12-11 센터 포 프로브 디벨롭먼트 앤드 커머셜리제이션 이관능성 킬레이트 및 그의 용도의 약동학적 증진
CA3062538A1 (en) 2017-05-05 2018-11-08 Fusion Pharmaceuticals Inc. Igf-1r monoclonal antibodies and uses thereof
JP7463006B2 (ja) * 2018-05-30 2024-04-08 トランスレイト バイオ， インコーポレイテッド ステロイド性部分を含むカチオン性脂質
EP4377323B1 (en) * 2021-07-27 2025-07-02 Bracco Imaging SPA Manufacturing of dimeric contrast agents
WO2025163025A1 (en) 2024-01-31 2025-08-07 Bracco Imaging Spa Pyridophane macrocyclic ligands and fe(iii) complexes thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1213029B (it) * 1986-01-30 1989-12-07 Bracco Ind Chimica Spa Chelati di ioni metallici paramagnetici.
US5057302A (en) * 1987-02-13 1991-10-15 Abbott Laboratories Bifunctional chelating agents
US5227474A (en) * 1987-02-13 1993-07-13 Abbott Laboratories Bifunctional chelating agents
DE440606T1 (de) * 1987-12-24 1992-02-27 Bracco Industria Chimica S.P.A., Mailand / Milano Macrocyclische chelatisierungsmittel und daraus hergestellte chelate.
DE3930696A1 (de) * 1989-09-14 1991-03-28 Hoechst Ag Gallensaeurederivate, verfahren zu ihrer herstellung, verwendung als arzneimittel
NO940115D0 (no) * 1994-01-13 1994-01-13 Nycomed Imaging As Kontrastmidler for roentgen- og magnettomografisk avbildning
JPH09512265A (ja) * 1994-04-20 1997-12-09 ニコムド サルター アイエヌシー コントラスト剤
IT1269839B (it) * 1994-05-26 1997-04-15 Bracco Spa Coniugati di acidi biliari, loro derivati con complessi metallici e relativi usi
US5833948A (en) * 1995-06-15 1998-11-10 Bracco Research S.A. Blood-pool imaging composition comprising micelles containing a lipophilic chelating agent and a non-ionic surfactant
JPH11116542A (ja) * 1997-10-06 1999-04-27 Sogo Pharmaceut Co Ltd γ−グルタミン酸アミド類の製造法

Also Published As

Publication number Publication date
WO2000038738A1 (en) 2000-07-06
RU2250765C2 (ru) 2005-04-27
RU2395490C2 (ru) 2010-07-27
EP1935435A3 (en) 2009-01-21
PL196474B1 (pl) 2008-01-31
EP1140209A1 (en) 2001-10-10
CA2355888C (en) 2009-02-24
AU773876B2 (en) 2004-06-10
ATE405296T1 (de) 2008-09-15
HK1042432B (zh) 2007-01-26
ITMI982802A1 (it) 2000-06-23
CZ302195B6 (cs) 2010-12-08
NO20013154D0 (no) 2001-06-22
HK1042432A1 (zh) 2002-08-16
KR20010099889A (ko) 2001-11-09
AU1980700A (en) 2000-07-31
CZ20012330A3 (cs) 2002-01-16
CN1263515C (zh) 2006-07-12
NO20013154L (no) 2001-08-23
HU228048B1 (en) 2012-09-28
ZA200104820B (en) 2002-06-13
RU2004127136A (ru) 2006-02-27
HUP0104715A2 (hu) 2002-04-29
EP1140209B1 (en) 2008-08-20
KR100736298B1 (ko) 2007-07-06
NO322551B1 (no) 2006-10-23
CN1854122A (zh) 2006-11-01
EP1935435A2 (en) 2008-06-25
IT1304501B1 (it) 2001-03-19
EP1935435B1 (en) 2017-09-06
HUP0104715A3 (en) 2005-11-28
CA2355888A1 (en) 2000-07-06
IL143730A (en) 2007-09-20
CN1333695A (zh) 2002-01-30
CN100450996C (zh) 2009-01-14
US6461588B1 (en) 2002-10-08
MXPA01006344A (es) 2002-06-04
JP4733271B2 (ja) 2011-07-27
PL349488A1 (en) 2002-07-29
JP2002533420A (ja) 2002-10-08
DE69939398D1 (de) 2008-10-02

Similar Documents

Publication Publication Date Title
IL143730A0 (en) Blood pool agents for nuclear magnetic resonance diagnostics
NO301829B1 (no) 2-pyridylmetylenpolyazamakrocyklo-fosfonsyrer, komplekser og farmasöytiske preparater basert på disse
NO954441D0 (no) Tricyklopolyazamakrocyklofosfonsyrer, komplekser og derivater derav for anvendelse som kontrastmidler
IS4172A (is) Joðuð meðseglandi chelates, aðferð til framleiðslu þeirra, notkun efnanna og aðferðir til að auka virkni efnanna
DK0560910T3 (da) I molekylsigte indesluttet paramagnetisk ion for diagnose
EP0463644A3 (en) Use of chelate complexes
ATE99544T1 (de) Liposomale radiologische kontrastmittel.
DK1110963T3 (da) Chlorin- og bakteriochlorinbaserede aminophenyl DTPA-konjugater til MR-kontraststoffer og radiofarmaka
AU4064401A (en) Bile acids conjugates with metal ion chelates and the use thereof
AU6061394A (en) Methods for the in vivo measurement of the concentration of NMR-detectable xenobiotic compounds
DE68926913D1 (de) Chelatbildende Verbindungen, die eine ortho-bindende Gruppe besitzen und ihre Komplexe
EP0579802A4 (en) Bicycle-polyazamacrocyclocarboxylic acid complexes, conjugates, preparation and use as contrast agents
ZA929576B (en) Bicyclopolyazamacrocyclophosphonic acids their complexes and conjugates for use as contrast agents and processes for their preparation
WO1991015466A3 (en) Aminopolycarboxylic acid chelating agents
WO2002066075A3 (en) Biotin-derivatives and their conjugates with chelating agents
FI933506L (fi) Bisyklopolyatsamakrosyklokarboksyylihappokomplekseja, niiden konjugaatteja, menetelmä niiden valmistamiseksi ja käyttö varjoaineina
FI933507L (fi) Bisyklopolyatsamakrosyklofosfonihappoja, niiden komplekseja ja konjugaatteja käytettäväksi varjoaineina ja menetelmä niiden valmistamiseksi
WO1995022544A3 (de) Substituierte 1,3,8-triaza-spiro(4,5)-decan-4-on-derivate als vorstufen zur herstellung von pharmazeutika
EP1234828A4 (en) MEANS TO IMPROVE LEARNING OR MEMORY

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed