WO1995022544A3 - Substituierte 1,3,8-triaza-spiro(4,5)-decan-4-on-derivate als vorstufen zur herstellung von pharmazeutika - Google Patents

Substituierte 1,3,8-triaza-spiro(4,5)-decan-4-on-derivate als vorstufen zur herstellung von pharmazeutika Download PDF

Info

Publication number
WO1995022544A3
WO1995022544A3 PCT/EP1995/000513 EP9500513W WO9522544A3 WO 1995022544 A3 WO1995022544 A3 WO 1995022544A3 EP 9500513 W EP9500513 W EP 9500513W WO 9522544 A3 WO9522544 A3 WO 9522544A3
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceuticals
production
triaza
decan
spiro
Prior art date
Application number
PCT/EP1995/000513
Other languages
English (en)
French (fr)
Other versions
WO1995022544A2 (de
Inventor
Wolfgang Brandau
Samuel Samnick
Original Assignee
Hoechst Ag
Wolfgang Brandau
Samuel Samnick
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag, Wolfgang Brandau, Samuel Samnick filed Critical Hoechst Ag
Priority to EP95908935A priority Critical patent/EP0745082A1/de
Publication of WO1995022544A2 publication Critical patent/WO1995022544A2/de
Publication of WO1995022544A3 publication Critical patent/WO1995022544A3/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Die Erfindung betrifft Verbindungen der allgemeinen Formel (I) als Vorstufen zur Herstellung neuer Pharmazeutika. Die genannten Pharmazeutika werden verwendet als Neuroleptika, Analgetika oder als Pharmaka in der Nuklearmedizin.
PCT/EP1995/000513 1994-02-18 1995-02-13 Substituierte 1,3,8-triaza-spiro(4,5)-decan-4-on-derivate als vorstufen zur herstellung von pharmazeutika WO1995022544A2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP95908935A EP0745082A1 (de) 1994-02-18 1995-02-13 Substituierte 1,3,8-triaza-spiro(4,5)-decan-4-on-derivate als vorstufen zur herstellung von pharmazeutika

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19944405178 DE4405178A1 (de) 1994-02-18 1994-02-18 Substituierte 1,3,8-Triaza-spiro(4,5)-decan-4-on-Derivate als Vorstufen zur Herstellung von Pharmazeutika
DEP4405178.6 1994-02-18

Publications (2)

Publication Number Publication Date
WO1995022544A2 WO1995022544A2 (de) 1995-08-24
WO1995022544A3 true WO1995022544A3 (de) 1996-09-26

Family

ID=6510551

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1995/000513 WO1995022544A2 (de) 1994-02-18 1995-02-13 Substituierte 1,3,8-triaza-spiro(4,5)-decan-4-on-derivate als vorstufen zur herstellung von pharmazeutika

Country Status (3)

Country Link
EP (1) EP0745082A1 (de)
DE (1) DE4405178A1 (de)
WO (1) WO1995022544A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2226058C (en) * 1997-01-30 2008-01-29 F. Hoffmann-La Roche Ag 8-substituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives
EP1087770A4 (de) 1998-06-15 2001-11-14 Merck & Co Inc Inhibitoren der prenyl-protein transferase
BRPI0417055A (pt) * 2003-12-02 2007-02-06 Pfizer Prod Inc processo para conversão de cetonas heterocìclicas em heterociclos amido-substituìdos
DE102005038141A1 (de) * 2005-08-12 2007-02-15 Grünenthal GmbH Substituierte 8-(3-Aminopropyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-on-Derivate

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155669A (en) * 1962-06-22 1964-11-03 Res Lab Dr C Janssen N V 2, 4, 8-triaza-spiro (4, 5) dec-2-enes
JPS49133380A (de) * 1973-04-25 1974-12-21
WO1989010759A1 (en) * 1988-04-29 1989-11-16 Mallinckrodt, Inc. Diaminedithiol chelating agents for radiopharmaceuticals

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155669A (en) * 1962-06-22 1964-11-03 Res Lab Dr C Janssen N V 2, 4, 8-triaza-spiro (4, 5) dec-2-enes
JPS49133380A (de) * 1973-04-25 1974-12-21
WO1989010759A1 (en) * 1988-04-29 1989-11-16 Mallinckrodt, Inc. Diaminedithiol chelating agents for radiopharmaceuticals

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 85, no. 13, 27 September 1976, Columbus, Ohio, US; abstract no. 94399s, page 641; *

Also Published As

Publication number Publication date
EP0745082A1 (de) 1996-12-04
DE4405178A1 (de) 1995-08-24
WO1995022544A2 (de) 1995-08-24

Similar Documents

Publication Publication Date Title
CA2130516A1 (en) New 11-benzaldoxime-estradiene derivatives, processes for their production and pharmaceuticals containing these substances
TW289020B (de)
AU6194894A (en) Bile acid derivatives, processes for their preparation and the use of these compounds as medicaments
AU661018B2 (en) Further novel 5-amino-4-hydroxyhexanoic acid derivatives as therapeutic agents
IE870610L (en) Hydroxylamine derivatives.
MY110110A (en) Pharmaceuticals in the treatment of gastrointestinal disorders, cardiovascular disorders and cns disorders
ZA965752B (en) Triphenylethylenes, process for their production, pharmaceutical preparations that contain these triphenylethylenes as well as their use for the production of pharmaceutical agents.
CA2262566A1 (en) Benzamidine derivatives and the use thereof as medicaments with ltb4-antagonistic effect
AU3548993A (en) Novel alkylenediammonium diclavulanate derivatives, a process for the preparation thereof as well as the use thereof
CA2138289A1 (en) N-substituted azabicycloheptane derivatives, the preparation and use thereof
AU7498494A (en) New bis-naphthalimides for the treatment of cancer
HUP0004588A3 (en) Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine-10-oles, method for the production and use thereof as medicaments and pharmaceutical compositions containing them
ZA941522B (en) New 4-aminopyridines - processes for their production as well as pharmaceutical agents containing them
TW241264B (de)
WO1995022544A3 (de) Substituierte 1,3,8-triaza-spiro(4,5)-decan-4-on-derivate als vorstufen zur herstellung von pharmazeutika
EP0618222A3 (en) Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid.
ZA949347B (en) 1,4,7,10-tetraazacyclododecane derivatives, their use, pharmaceutical agents containing these compounds and process for their production.
EP0487996B1 (de) 3-substituierte Cephalosporine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
HRP930131A2 (en) Amino-ascorbic acid derivatives, process for the preparation and use thereof
CA2292017A1 (en) Substituted cycloheptenes, their preparation and use
AU2886595A (en) Technetium-sulphonamide complexes, their use, pharmaceutical agents containing the latter, as well as process for the production of the complexes and agents
AU3574293A (en) Novel azole derivative, production thereof and pharmaceutical composition
EP0353631A3 (de) Isoxazolobenzoxazepine, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
EP0641764A3 (de) Verfahren zur Herstellung von Hydroxyalkylaminonitrobenzol-Derivaten.
AU6291794A (en) Pyridothiazineacetic acid compound, process for producing the same, and use thereof

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): CA FI JP NO US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 1995908935

Country of ref document: EP

AK Designated states

Kind code of ref document: A3

Designated state(s): CA FI JP NO US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

WWP Wipo information: published in national office

Ref document number: 1995908935

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: CA

WWW Wipo information: withdrawn in national office

Ref document number: 1995908935

Country of ref document: EP